Faktor Risiko Kematian Neonatal Dini di Rumah Sakit Bersalin

Angka kematian bayi di Indonesia masih tergolong tinggi, kematian neona- tal 50% terjadi pada bayi berat lahir rendah (BBLR) dan lebih dari 50% ke- matian bayi adalah kematian neonatal dini. Penelitian ini bertujuan untuk mengetahui faktor-faktor antenatal care (ANC), status imunisasi Tetanus Toxoid (TT) ibu hamil, anemia pada saat hamil, berat lahir, status paritas, dan status hipotermia terhadap kematian neonatal dini. Penelitian meng- gunakan desain penelitian case control di Rumah Sakit Bersalin Kota Makassar dengan sampel 40 kasus dan 120 kontrol. Data diperoleh melalui wawancara langsung dengan responden. Hasil penelitian menunjukkan bahwa faktor risiko kejadian kematian neonatal dini meliputi ANC (nilai p = 0,000; odds ratio, OR = 7,333; CI 95% = 2,966 - 18,129), status imunisasi TT (nilai p = 0,000; OR = 19,205; CI 95% = 7,902 - 46,678), anemia ibu hamil (nilai p = 0,000; OR = 32,818; CI 95% = 7,549 - 142,674), berat lahir (nilai p = 0,000; OR = 122,212; CI 95% = 32,324 - 462,068), status paritas (nilai p = 0,000; OR = 5,537; CI 95% = 2,029 - 15,111), status asfiksia (ni- lai p = 0,000; OR = 8,197; CI 95% = 0,452 - 2,745). Status hipotermia bukan merupakan faktor risiko kematian neonatal dini (nilai p = 0,815; OR = 1,114; CI 95% = 3,646 mukan bahwa berat lahir bayi merupakan faktor yang paling berisiko ter- hadap kematian neonatal dini (nilai p = 0,000). Kata kunci: Faktor risiko kematian, neonatal dini, angka kematian bayi, bayi berat lahir rendahAbstractInfant mortality rate in Indonesia is still high. Fifty percent of the neonatal mortality occurred among low birth weight infants (LBWI) and neonatal mortality within 7 days of life accounted for 50% of total infant mortalities. This study was aimed to examine the extent of early neonatal mortality risk by antenatal care (ANC), Tetanus Toxoid (TT) immunization status of pregnant women, anemia during pregnancy, birth weight of neonatal, parity status, and hypothermia status.This study was a case control study with direct interview to respondents, conducted in the Maternity Hospital of Makassar with 40 cases and 120 controls. Samples were selected by purposive sam- pling. Study results indicated that risk factor of early neonatal mortality were ANC (p value = 0,000; odds ratio, OR = 7,33; CI 95% = 2,966 - 18,129), TT immunization status (p value = 0,000; OR = 19,205; CI 95% = 7,902 - 46,678), pregnancy anemia (p value = 0,000; OR = 32,818; CI 95% = 7,549 - 142,674), birth weight (p value = 0,000; OR = 122,212; CI 95% = 32,324 - 462,068), parity status (p value = 0,000; OR = 5,537; CI 95% = 2,029 - 15,111), asphyxia status (p value = 0,000; OR = 8,197; CI 95% = 0,452 - 2,745), whereas hypothermia status (p value = 0,815; OR = 1,114; 0,452 - 2,745) was not a risk factor. Results of logistic regression multivariate analysis indicated that infant’s birth weight was the most risk factor of early neonatal mortality (p value = 0,000). Specific surveillance program for high risk neonatal needed to be arranged in all health centers.Key words: Mortality risk factor, early neonatal, infant mortality rate, low birth weight infants

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Early neonatal mortality rate and the risk factors in Wangaya hospital

Paediatrica Indonesiana ◽

10.14238/pi48.5.2008.306-11 ◽

2016 ◽

Vol 48 (5) ◽

pp. 306

Author(s):

Made Lndah Nastiti Utami Budha ◽

Wayan Retayasa ◽

Made Kardana

Keyword(s):

Risk Factors ◽

Birth Weight ◽

Mortality Rate ◽

Neonatal Mortality ◽

Gestational Age ◽

Neonatal Death ◽

Early Neonatal Death ◽

Neonatal Mortality Rate ◽

Early Neonatal Mortality ◽

Early Neonatal Mortality Rate

Background The first week of life of a neonate is a critical period.In Asia, early neonatal mortality rate remains high.Objective To investigate early neonatal mortality rate and the riskfactors in Wangaya Hospital.Methods A cross sectional study was carried out retrospectivelyon neonates registered at Perinatology Unit, Wangaya HospitalDenpasar, Bali since January 2006. The study was done fromOctober to November 2007. Data was obtained from medicalrecord, analyzed as univariate using chi-square test or Fisher'sexact test and multivariate logistic regression analysis model.Results Early neonatal mortality rate in Wangaya Hospital was 38.7per 1000 livebirths. Univariate analyses showed that there werefive significant risk factors of early neonatal death, i.e., respiratorydistress, asphyxia, birth weight less than 2500 grams, sepsis, andgestational age less than 3 7 weeks. Multivariate analysis showedthat those five variables were significant as risk factors of earlyneonatal death i.e., OR (95% confidence interval) for respiratorydistress: 16.8 (3.7 to 76.6)], asphyxia: 13.5 (6.1 to 29.9)], birthweight <2500 grams: 8.1 (3.3 to 19.9)], sepsis: 7.3 (3.1 to 17.1),and gestational age <37 weeks: 3.5 (1.6 to 7.8)].Conclusions Early neonatal mortality rate in Wangaya Hospitalremains high. Respiratory distress, asphyxia, birth weight <2500gram, sepsis, and gestational age <37 weeks were independent riskfactors of early neonatal death.

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Study of correlation between gestational age and new-born foot length and chest circumference

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20183523 ◽

2018 ◽

Vol 5 (5) ◽

pp. 1875 ◽

Cited By ~ 1

Author(s):

Aayush Gupta ◽

Gunjan Kela Mehrotra ◽

Swati Mulye

Keyword(s):

Birth Weight ◽

Mortality Rate ◽

Neonatal Mortality ◽

Child Mortality ◽

Gestational Age ◽

Chest Circumference ◽

P Value ◽

Positive Correlation ◽

New Born ◽

Foot Length

Background: Globally, in 2015, 1 million children died on first day of their life. The neonatal mortality rate is declining less rapidly than the mortality rate for children between 1month and 5 years of age. Thus, contribution of the neonatal mortality to the under-five deaths is increasing. Usually as average income of a country increases, it leads to decline in child mortality yet some countries in the fast lane for global economic growth such as India have been in the slower lane for child mortality reduction.Methods: This study was conducted at Sri Aurobindo Medical College and PG Institute, Indore from October 2015 to March 2017 for period of 18 months. Total of 800 live new-borns were included in this study by simple random technique. The statistical analysis of data was done using SPSS for Windows (Version 20.0) software. The correlation of gestational age with new-born foot length and new-born chest circumference was analysed by applying correlation and regression analysis.Results: Foot length is significantly correlated with both gestational age and birth weight with p value of < 0.05 and highly positive correlation coefficient. Chest circumference is significantly correlated with both gestational age and birth weight with p value of < 0.05 and highly positive correlation coefficient.Conclusions: This study tried to identify anthropometric parameter (foot length and chest circumference) which allows for rapid evaluation of the infant for gestational age and provide at risk infants with timely care.

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THE RISK FACTOR TOWARDS CHILDBIRTH WITH CAESAREAN (SECTION)

10.31227/osf.io/zfa5v ◽

2018 ◽

Author(s):

ANDI NURAINA SUDIRMAN

Keyword(s):

Logistic Regression ◽

Risk Factor ◽

Caesarean Section ◽

Antenatal Care ◽

Control Design ◽

Case Control ◽

P Value ◽

Regression Result ◽

Statistic Analysis ◽

Logistic Regression Result

Caesarean (section) is one way of childbirth by giving the surgery acted. According to the Base of Heath Research (Riskesdas) 2010, the number of Caesarean (section) in Indonesia has passed maximal limit of WHO standard that is 5 – 15 %. Therefore, a research has been held to see the risk factor towards childbirth with Caesarean (section) at Sitti Khadijah mom and baby hospital, Gorontalo. Type of this research is analytic by using case control design with sample is that consist of 68 cases and 68 control. The data is analyzed by statistic analysis logistic regression. Result of the research shows that parity, distance between pregnancy, check-up of antenatal care and disease complication history have risk towards childbirth with Caesarean (section). The variable that is more risky towards childbirth with Caesarean (section) is the disease complication history with p value = 0,000 (Cl 95 %) and OR value = 9,430 (3,861 – 23,035). Suggested for health parties to be more active in promotion program about childbirth, check-up of antenatal care, etc. in the way of deciding the policy in selecting Caesarean (section).

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Hubungan Frekuensi Kunjungan Antenatal Care (ANC) dengan Kejadian Prematur

Jurnal Ners dan Kebidanan Indonesia ◽

10.21927/jnki.2014.2(1).27-31 ◽

2016 ◽

Vol 2 (1) ◽

pp. 27

Author(s):

Evi Esti Utami ◽

Susi Ernawati ◽

Winda Irwanti

Keyword(s):

Birth Weight ◽

Antenatal Care ◽

Total Population ◽

Perinatal Death ◽

Control Design ◽

Case Control ◽

Premature Baby ◽

P Value ◽

Statistic Analysis ◽

Control Groups

<p>The cause of infant mortality is mostly due to perinatal matters. Almost 2-27% of all perinatal death is caused by prematurity with low birth weight (BBLR). Reducing mortality rate on perinatal can be achieved by observing all pregnant women and ﬁ nding as well as addressing inﬂ uenced factors of neonatal safety. This research aims to identify correlation between frequencies of Antenatal Care (ANC) with incidence of prematurity. This is an observational study with case-control design using retrospective approach. Total population was 1335 and of 156 was choosen as research respondents deviding into 78 as case respondents and 78 as control groups. The result of statistic analysis showed that p value=0,837 (p>0,05) means frequencies of ANC did not have correlation with prematurity. Conclusion, (1) during the period of 1 January 2011 and 29 February 2012, it found 207 (8,13%) premature baby delivered, (2) at about 80,8% mother who delivered premature baby had normal ANC 4 times or more with the pattern 1-1-2 in every semester, (3) statistically ANC was not having correlation with premature baby.</p>

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Myelodysplastic Syndromes and Acute Myelogenous Leukemia Resulting from Therapy for Autoimmune Disease, a Case-Control Cohort Study

Blood ◽

10.1182/blood.v126.23.5636.5636 ◽

2015 ◽

Vol 126 (23) ◽

pp. 5636-5636

Author(s):

Natalie Ertz-Archambault ◽

Heidi Kosiorek ◽

Janna Castro ◽

Gretchen Taylor ◽

Robert Marino ◽

...

Keyword(s):

Risk Factor ◽

Mayo Clinic ◽

Odds Ratio ◽

Conditional Logistic Regression ◽

Case Control ◽

Myelogenous Leukemia ◽

Cytotoxic Agents ◽

Control Group ◽

P Value ◽

Seer Data

Abstract Background Cytotoxic agents are a well-established risk factor for therapy related myeloid neoplasms (t-MN). The incidence of t-MN in patients (pts) with autoimmune diseases (AID) treated with cytotoxic and immuno-modulatory agents are not well described in the literature. Most case series assess an MDS/AML population and co-occurrence with an AID. To our knowledge, there exists no large case-control studies evaluating a primary AID population that developed therapy-related MDS or AML, and the relationship to detailed therapeutic intervention for AID. Our study queries the association of cytotoxic and immune-modulating agents to treat AID as risk factor for developing MDS or AML. Methods Between 2004-2014, 23,671 pts with an ICD-9 coded AID were seen at Mayo Clinic Arizona; 148 pts from this population had a concomitant coded diagnosis of MDS/AML. In an IRB approved, retrospective chart review we confirmed 61 cases meeting strict inclusion criteria. We performed a case-control match from the same primary AID population for age, gender, and autoimmune specific diagnosis at a 2:1 ratio. AML/MDS cases were compared to controls by use of chi-square test for frequency data. Odds ratios with 95% confidence interval were constructed using conditional logistic regression. Case incidence was compared to SEER data for the general population Results Of 61 cases 33 were MDS, 20 de-novo AML, and 8 MDS transformed to AML. Psoriasis 16 (26.2%) and rheumatoid arthritis 14 (23.0%) were the most common autoimmune diagnoses, followed by systemic lupus 11 (18%), Crohn's disease 7 (11.5%), and ulcerative colitis 5 (8.2%). 39 out of 61 cases (63.9%) received either a cytotoxic or immune modulating agent for AID, compared to 64/122 (52.5%) in the control group; p=0.140. 7/61 cases (11.5%) received both a cytotoxic and immune modulating agent as compared to 16/122 (13.1%) in controls; p=0.753. Overall, the case population received more agents than controls. No cytotoxic or immune-modulating treatment was documented in 16% of cases and 36% controls. Exposures to cytotoxic and immune-modulating agents were similar in both case and control cohorts. Exposure time was not statistically significant. Azathioprine was the only statistically significant agent exposure observed more often in the case cohort than control. Per SEER data, over a 10-year period in a general age-matched population that is comparable to our AID population cohort, we would expect 54 MDS and 35 AML cases. Table 1. Exposures and Timeline Cases (n=61) Controls (n=122) P value * Number of Systemic Agents, Total None 1 2 3 4+ - 10 (16.4%) 26 (42.6%) 12 (19.7%) 7 (11.5%) 6 (9.8%) - 44 (36.1%) 32 (26.2%) 31 (25.4%) 9 (7.4%) 6 (4.9%) 0.020 Exposure to Cytotoxic agent < 1 year 2-5 years 6-10 years 11 years or more Unknown (n=26) 7 (26.9%) 6 (23.1%) 5 (19.2%) 3 (11.5%) 5 (19.2%) (n=43) 5 (11.6%) 8 (18.6%) 6 (13.9%) 12 (27.9%) 12 (27.9%) 0.276 Exposure to Immune modulating agent < 1 year 2-5 years 6-10 years 11 years or more Unknown (n=20) 6 (30%) 6 (30%) 3 (15%) 1 (5%) 4 (20%) (n=37) 6 (16.2%) 10 (27.0%) 5 (13.5%) 3 (8.1%) 13 (35.1%) 0.661 Table 2. Treatments and Odds Ratio Odds Ratio 95% CI for OR P value * Cytotoxic OVERALLAzathioprine Cyclophosphamide Methotrexate Mitoxantrone 6-MP Mycophenolate 1.39 4.16 1.28 0.74 2.73 1.00 1.21 0.72, 2.67 1.29, 13.44 0.24, 6.89 0.29, 1.88 0.23, 33.0 0.23, 4.35 0.28, 5.21 0.322 0.017 0.773 0.528 0.429 0.999 0.803 Immune modulating agent OVERALLAnti-TNF Leflunomide Plaquenil 1.19 0.73 2.00 2.73 0.52, 2.73 0.24, 2.24 0.40, 9.91 0.80, 8.33 0.672 0.585 0.396 0.077 Discussion Treatment of AID does not seem to increase the incidence of MDS or AML. Furthermore, the incidence of myeloid neoplasm occurring in association with treatment of AID is not higher than expected in the general SEER population. However, the case cohort was exposed to more agents overall and more likely to have exposure to azathioprine than controls. Limitations of our study are associated with its retrospective nature, possible associated underrepresentation of t-MN, and autoimmune population profile. Nevertheless, this is the largest case study with detailed drug exposures with timelines for pts with AID, contributing to a better understanding regarding possible risk of developing MDS/AML in pts treated for AID. Confirmation of the same study at Mayo Clinic Rochester and Florida are ongoing. Disclosures Al-Kali: Novartis: Research Funding.

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Pengaruh Perawatan Metode Kanguru (PMK) terhadap Pencegahan Hipotermi pada Bayi Baru Lahir

Jurnal Bidan Cerdas (JBC) ◽

10.33860/jbc.v2i2.56 ◽

2020 ◽

Vol 2 (2) ◽

pp. 66-71

Author(s):

Parti ◽

Sumiati Malik ◽

Nurhayati

Keyword(s):

Birth Weight ◽

Infant Mortality ◽

Low Birth Weight ◽

Health Workers ◽

Kangaroo Mother Care ◽

Infant Mortality Rate ◽

P Value ◽

Low Birth Weight Infants ◽

Low Birth Weight Babies ◽

Before And After

Most causes of infant death are problems that occur in newborn/neonatal (0-28 days old), Low Birth Weight Babies (LBW) is one of the factors which has a contribution to infant mortality, especially in the neonatal period. Infant Mortality Rate (IMR) is a benchmark in determining the degree of public health, both at the National and Provincial levels. This study aimed to determine the effect of the Kangaroo Mother Care Method (KMC) on the prevention of hypothermia in low birth weight infants at Morowali District Hospital in 2019. The type of research used was a quasi-experiment. The population is all low birth weight babies born from May to July 2019. The sample in this study was all newborns with low birth weight born from May to July 2019, totaling 30 babies. There is a difference (influence) on the baby's body temperature before and after KMC with a p-value=0,000. The kangaroo mother care can continue to be affiliated considering its benefits for both infants and mothers, as well as increasing the ability of health workers in conducting KMC so that they can provide in-house training for mothers to be carried out at home.

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FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN BBLR DI RUMAH SAKIT UMUM DAERAH PALEMBANG BARI TAHUN 2013

Jurnal Kebidanan : Jurnal Medical Science Ilmu Kesehatan Akademi Kebidanan Budi Mulia Palembang ◽

10.35325/kebidanan.v4i2.60 ◽

2019 ◽

Vol 4 (2) ◽

Author(s):

Juliana Widyastuti Wahyuningsih Juliana Widyastuti Wahyuningsih

Keyword(s):

Birth Weight ◽

Mortality Rate ◽

Low Birth Weight ◽

Random Sampling ◽

Maternal Age ◽

Univariate Analysis ◽

Infant Mortality Rate ◽

Survey Method ◽

P Value ◽

Chi Square

ABSTRACT Low birth weight (LBW) infants with birth weight is less than 2500 grams, regardless of gestational age. Statistically showed 90 % incidence of LBW obtained in developing countries with a mortality rate 35 times higher tinggi.Di South Sumatra Province Infant Mortality Rate ( IMR ) is 29 per 1,000 live births. In Palembang BARI hospitals incidence of LBW in 2013 amounted to 317 cases . The purpose of this study is to determine is there a relationship between the factors of age, education, and parity with the incidence of Low Birth Weight in Palembang BARI hospitals in 2013. This study used survey method crosss sectional analytic approach. The study population was all women who gave birth and was admitted to hospital obstetrics Palembang BARI installations in 2013 amounted to 901. This research was conducted in February 2014. Samples were taken with a random sampling method sistematic. Analyze data using statistical test Chi - Square. Results of univariate analysis of this study showed that 193 (69.4 %) of the respondents had low birth weight, and 85 (30.6 %) respondents had BBLN. 63 (22.7 %) of respondents with a high risk of maternal age and 215 (77.3 %) of respondents with a low risk of maternal age. 157 (56.5 %) respondents with low education mothers and 121 (43.5 %) of respondents with higher education mothers. 48 (17.3 %) respondents with high parity mothers and 230 (82.7 %) respondents with low parity mothers. So the bivariate analysis showed no significant association between maternal age with the incidence of LBW with P value = 0.035, no significant association between education and the incidence of LBW with P value = 0.006, and no significant relationship between the incidence of low birth weight with parity P value = 0.041. It is recommended for health care workers (midwives) hospital in order to be used as material information regarding the occurrence of LBW and as an input as well as the evaluation of success in good health or when needed to do counseling and care of LBW, especially to mothers who give birth to low birth weight baby. ABSTRAK Berat badan lahir rendah (BBLR) adalah bayi dengan berat lahir kurang dari 2500 gram tanpa memandang masa gestasi. Secara statistik menunjukkan 90% kejadian BBLR didapatkan di negara berkembang dengan angka kematiannya 35 kali lebih tinggi.Di Propinsi Sumatera Selatan Angka Kematian Bayi (AKB) sebesar 29 per 1.000 kelahiran hidup. Di RSUD Palembang BARI Tahun 2013 angka kejadian BBLR berjumlah 317 kasus. Tujuan Penelitian ini adalah untuk mengetahui adakah hubungan antara faktor umur, pendidikan, dan paritas dengan kejadian Berat Badan Lahir Rendah di RSUD Palembang BARI Tahun 2013. Penelitian ini menggunakan metode survey analitik dengan pendekatan crosss sectional. Populasi penelitian ini adalah semua ibu yang melahirkan dan dirawat inap di instalasi kebidanan RSUD Palembang BARI Tahun 2013 berjumlah 901. Penelitian ini dilakukan pada bulan Februari 2014. Sampel penelitian diambil dengan metode sistematic random sampling. Analisa data menggunakan uji statistik Chi – Square. Hasil penelitian analisis univariat ini menunjukkan bahwa 193 (69,4%) responden mengalami BBLR, dan 85 (30,6%) responden mengalami BBLN. 63 (22,7%) responden dengan umur ibu resiko tinggi dan 215 (77,3%) responden dengan umur ibu resiko rendah. 157 (56,5%) responden dengan ibu pendidikan rendah dan 121 (43,5%) responden dengan ibu pendidikan tinggi. 48 (17,3%) reponden dengan ibu paritas tinggi dan 230 (82,7%) responden dengan ibu paritas rendah. Sehingga analisa bivariat menunjukkan ada hubungan yang bermakna antara umur ibu dengan kejadian BBLR dengan P value = 0,035, ada hubungan yang bermakna antara pendidikan dengan kejadian BBLR dengan P value = 0,006 dan ada hubungan yang bermakna antara paritas dengan kejadian BBLR dengan P value = 0,041. Disarankan bagi petugas kesehatan (bidan) rumah sakit agar dapat dijadikan sebagai bahan informasi mengenai terjadinya BBLR dan sebagai bahan masukan serta evaluasi keberhasilan dalam pelayanan kesehatan yang baik atau bila perlu dilakukannya penyuluhan serta asuhan tentang BBLR khususnya kepada ibu yang melahirkan Bayi dengan BBLR.

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