Determining Some Factors Affecting the Longevity of Hemodialysis Patients. Using Survival Analysis

2019 ◽  
Author(s):  
Shideh Rafati ◽  
Laleh Hassani ◽  
Mohamad Tamaddondar ◽  
Abdolnabi Sabili
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Survival Time ◽  
Proportional Hazards Model ◽  
Cox Model ◽  
The Body ◽  
Dialysis Session ◽  
Dialysis Unit ◽  
Risk Of Death ◽  
Risk Of Mortality

Abstract Background Dialysis is a method for removing excess fluid and uremic waste from the body of chronic renal-failure patients. In patients with CRF, blood dialysis stops death. Hemodialysis prevents the death of patients with chronic renal failure. Various factors can affect the survival of patients undergoing dialysis treatment. The current study aimed to determine such factors.Methods This descriptive-analytic study examined 252 patients undergoing dialysis from 2010 to 2016 in all of hospitals in Bandar Abbas- Iran, whose data had been recorded in the dialysis unit or it was possible to get their files. The study used Lasso Regression in Cox's proportional hazards model in case with multi variables, background diseases, Body Mass Index,…… The collected data was analyzed using SPSS software and through installing glmnet and survival packages in R software.Results In this study, 35 (13.9%) death events and 217 (86.1%) censored events were observed. The mean survival time of 252 patients was equal to 10.93 ± 7.82 years and the median survival time of these patients was calculated to be ten years. Based on the results of the Cox model under the penalized method of Lasso, The risk of mortality for patients with diploma degree was by 49% lower than that of the illiterate group (HR = 0.51). The risk of death for unemployed patients and farmers was equal to 0.66 (HR = 1.66) and 0.29 (HR = 1.29), respectively, higher than that of employees. Another significant factor in this study is the duration of each dialysis session. The risk of mortality has been reduced by 0.34 (HR = 0.66) for a single increase during dialysis.Conclusions Apart from congenital and underlying diseases which early diagnosis will prevent kidney failure, the risk of mortality will be reduced by training behavioral issues in patients undergoing dialysis such as dialysis at predetermined hours and times and appropriate nutritional behaviors.

scholarly journals Expected ages in the patients of chronic diseases

2016 ◽  
Vol 10 (4) ◽  
Author(s):  
Intesaruk Rashid Khan ◽  
Ahmed Imran Siddiqui ◽  
Wafa Aftab
Keyword(s):  
Heart Failure ◽  
Renal Failure ◽  
Retrospective Study ◽  
Chronic Disease ◽  
Chronic Renal Failure ◽  
Hepatic Cirrhosis ◽  
Disease Process ◽  
Chronic Illnesses ◽  
The Body ◽  
Medical Wards

This retrospective study was conducted to find out the expected ages in the patients of hepatic cirrhosis, chronic renal failure and heart failure. This study thus covers most of the patients of out medical wards presenting with chronic illnesses. On comparison of these expected ages it is also found that the expected age in all these three groups is not much different. So, the disease process or the mechanism of the chronic disease in the body may be different, but somehow the final out come is not much different in terms of life span.

scholarly journals CHRONIC KIDNEY DISEASE

2018 ◽  
Vol 25 (06) ◽  
pp. 887-891
Author(s):  
Tanveer Fatima ◽  
Aurangzeb Afzal ◽  
Sania Ashraf
Keyword(s):  
Renal Failure ◽  
The Body ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Waste Products ◽  
Dialysis Unit ◽  
Complex Procedure ◽  
Back Ache ◽  
Life Threatening ◽  
Stage Renal Disease

Introduction: Hemodialysis is a process of removal of waste products andtoxic substances from the body using an extracorporeal system. During the procedure, lotsof hemodynamic and metabolic changes occur in the body as a result of which patientsundergoing hemodialysis may suffer from complications both acutely during or just after dialysisas well as in long term. Objective: To determine the frequencies of various acute intradialyticcomplications in our hemodialysis patients. Study Design: Cross sectional survey. Setting:Lahore General Hospital, Lahore. Period: 3 months from May 2017 to July 2017. Method:End stage renal disease patients on regular hemodialysis in the dialysis unit of a tertiary carehospital. A total of 81 patients were included in the study. Patients with acute renal failure andacute on chronic renal failure were excluded from the survey. Results: Common complicationsobserved in our studied population included muscle cramps (70.7%), post dialysis fatigue(57.3%), back ache (56.1%), intradialytic shivering (57.3%), hypoglycemia (21.4%), hypotension(37.8%), hypertension (8.5%), headache (13.4%), vomiting (13.4%) and anaphylaxis in 2.4%.Conclusion: Hemodialysis is a complex procedure and can cause many complications mostof which are not life threatening. With proper monitoring and immediate treatment thesecomplications can be overcome without causing interruption in hemodialysis.

scholarly journals THE INNTERRELATED FACTORS OF ANEMIA LEVEL ON CHRONIC KIDNEY DISEASE PATIENTS POST DIALYSIS IN DIALYSIS UNIT OF BETHESDA HOSPITAL YOGYAKARTA

2017 ◽  
Author(s):  
Vivi Retno Intening
Keyword(s):  
Chronic Kidney Disease ◽  
Renal Failure ◽  
Logistic Regression ◽  
Chronic Renal Failure ◽  
Kidney Disease ◽  
Measurement Instrument ◽  
Nutrition Status ◽  
Cross Sectional ◽  
Dialysis Unit ◽  
Age Factor

Background of the Research: A Chronic Kidney Disease (CKD) is a kind of disease (or a renal failure) which shows significant number of rising evidence in recent years. A patient of chronic renal failure needs a renal succession therapy such as dialysis in order to make a longer life. When the disease is getting worst, the patient is generally suffering anemia as the effect of the renal damaged. The interrelated factors of the anemia level are: age, sex, the period of dialysis therapy, nutrition status, illness-stadium, and the enclose disease.Significance of the Research: This research is conducted in order to know the interrelated factors of anemia level in chronic renal failure patients post dialysis.Research Methods: This is a non-experiment correlation research with a cross sectional approximation. The research is conducted in the Dialysis Unit of Bethesda HospitalYogyakarta, from February to March 2009. The researcher uses purposive sampling with 30 respondents. The measurement instrument is observation sheets and hemoglobin tests. The data analysis is done through distribution frequency; Kolmogorov-Smirnov test for the bivariate analyses and Logistic Regression for the multivariate analyses.Research findings: The research which was conducted on 30 respondents showed result of 93, 3% easy-anemia patients’ sufferings. The age factor, sex, dialysis period, nutrition status, illness-stadium, and the enclose disease were statistically unrelated to the level of anemia, with p>0, 05. The statistic accounting of logistic regression showed that the illness-stadium was the most probable factor related to the level of anemia, with p=0, 09 ;CI=0, 734 – 73, 248; Exp (B) 7, 333.Conclusion: The age factor, sex, dialysis period, nutrition status, illness-stadium, and the enclose disease were statistically unrelated to the level of anemia, but the most probable factor related to the level of anemia was the illness-stadium.Keywords: Chronic Kidney Disease, Anemia Level, Dialysis

ANTITHROMBIN III AND HEPARIN COFACTOR II IN PATIENTS WITH CHRONIC RENAL FAILURE

1987 ◽  
Author(s):  
P Toulon ◽  
C Jacquot ◽  
M O Frydman ◽  
D Vignon ◽  
M Aiach
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Plasma Proteins ◽  
Blood Donors ◽  
Dermatan Sulfate ◽  
Control Group ◽  
Dialysis Session ◽  
Heparin Cofactor Ii ◽  
At Iii ◽  
Before And After

Anti thrombin III (AT III) and heparin cofactor II (HC II) were measured in 77 blood donors, 82 patients with chronic renal failure (CRF) undergoing regular hemodialysis and 36 undialyzed patients with CRF. AT III was measured as heparin cofactor and HC II as dermatan sulfate cofactor using amidolytic assays.The results (mean ± SD expressed in percentage of the in pooled normal plasma) are summurized in the table.Subnormal AT III levels were found in both dialyzed and undialyzed patients with CRF, while HC II was significantly (p < 0.001) reduced in dialyzed patients (12 of them were found to have HC II levels below to lowest value founded in our control group: 68 %).In order to explain this decrease of HC II level in dialyzed patients with CRF, we compared both AT III and HC II activities before and after a dialysis session in 24 patients (12 with a low and 12 with normal before dialysis HC II activity). AT III and HC II increased significantly (p < 0.01) in all patients after dialysis. When related to total plasma proteins in order to suppress the influence of hemoconcentration induced by dialysis, AT III decreased significantly (p < 0.01) in the 24 patients while HC II increased significantly (p < 0.01) only in patients with low before dialysis HC II levels (the increase in HC II activity was found significantly in the pooled 24 patients).

Abstract P017: Serum N-Carboxymethyl-Lysine and Risk of Mortality in Older Adults

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Mary Lou Biggs ◽  
David Benkeser ◽  
Joachim Ix ◽  
Jorge Kizer ◽  
Luc Djousse ◽  
...  
Keyword(s):  
Renal Failure ◽  
Mortality Risk ◽  
Community Dwelling ◽  
Cardiovascular Health Study ◽  
Risk Of Death ◽  
Risk Of Mortality ◽  
Organ Systems ◽  
Increased Risk ◽  
Carboxymethyl Lysine ◽  
The Mean

Advanced glycation end products (AGEs) are compounds formed by the non-enzymatic glycation of proteins, lipids, and nucleic acids, and are thought to play a role in the pathogenesis of diseases across multiple organ systems. Carboxymethyl-lysine (CML) is a dominant AGE found in tissue proteins and in the circulation, and a commonly used AGE biomarker. Only a few epidemiological studies have evaluated the association between circulating CML and mortality risk, and none have evaluated the association between CML and cause-specific non-CVD mortality. We measured CML by ELISA on serum specimens collected from 3,373 Cardiovascular Health Study participants in 1996. Participants were followed for death through 2010, and cause of death was classified using death certificates, medical records, and proxy interview. We used Cox regression to estimate the relative risk of total and cause-specific mortality associated with circulating CML, adjusting for confounders (Models 1 & 2) and estimated glomerular filtration rate (eGFR) as a potential mediator (Model 3). We tested whether sex or diabetes modified the association between CML and mortality. The mean age among participants was 78 years and 60% were women. The mean CML level among participants was 629 ng/mL. Over median follow-up of 10 years, 2,322 deaths occurred (73.4 per 1,000 person-years). After adjustment for confounders (Models 1 & 2), CML was associated with an increased risk of death from CVD, dementia, infection, fracture/trauma, and renal failure (Table). Aside from renal failure, adjustment for eGFR attenuated the HR estimates modestly. There was no evidence for effect modification of the association of CML and all-cause mortality risk by sex or diabetes. In a cohort of community-dwelling older individuals, elevated circulating CML was associated with increased risk of mortality from cardiovascular causes, dementia, infection, fracture/trauma, and renal failure. A portion of the increased risk may be mediated through decreased renal function.

Calciphylaxis in Renal Hyperparathyroidism: A Case-based Review

2016 ◽  
Vol 8 (2) ◽  
pp. 156-159
Author(s):  
Rajeev Parameswaran ◽  
Sandra Tan ◽  
Ngiam K Yuan ◽  
Diana GZ Lim
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
High Mortality ◽  
Severe Pain ◽  
Lower Extremities ◽  
The Body ◽  
Renal Hyperparathyroidism ◽  
Case Based

ABSTRACT Calciphylaxis is a rare fatal condition associated with chronic renal failure, with a prevalence of about 4%. The condition is associated with microcalcification of small- and medium-sized arteries, leading to skin ischemia, necrosis, and gangrene. Any part of the body may be involved, but it is predominant in the lower extremities. Severe pain is usually associated with ulcers and may be difficult to manage. Although parathyroidectomy may improve the symptoms, the prognosis remains dismal with a high mortality. We present a case of severe calciphylaxis associated with renal hyperparathyroidism and briefly review the literature on the condition. How to cite this article Tan S, Yuan NK, Lim DGZ, Parameswaran R. Calciphylaxis in Renal Hyperparathyroidism: A Case-based Review. World J Endoc Surg 2016;8(2):156-159.

scholarly journals Etiology and outcome of peritoneal dialysis in 100 patients with chronic renal failure in Al-Ramadi Teaching

2020 ◽  
Vol 7 (2) ◽  
pp. 41-48
Author(s):  
Haitham N. AL-Koubaisy
Keyword(s):  
Renal Failure ◽  
Peritoneal Dialysis ◽  
Chronic Renal Failure ◽  
Teaching Hospital ◽  
Obstructive Uropathy ◽  
The Body ◽  
Common Disease ◽  
Human Beings ◽  
Significant Difference ◽  
Common Causes

Chronic renal failure is fatal disease because it leads to failure of excretory ,metabolic and endocrine functions of the kidneys which lead to disturb all physiological functions of the body some of these derangements is fatal to human beings to save human these body disturbances by chronic renal failure is treated by renal transplant and dialysis in different ways including peritoneal dialysis (PD.). Chronic renal failure is a common disease in patients attending Ramadi teaching hospital whom treated by peritoneal dialysis (PD) with variable results . So this study is introduced to detect the health status for managing chronic renal failure treated by peritoneal dialysis. All patients were 100 patients (53 male and 47 female) with CRF who admitted to the medical word in Al-Ramadi teaching hospital during a period from November 2008 till July 2009. Thorough history, examination and investigations were done for them including: hemoglobin, ESR ,blood urea, serum creatinine, ECG and abdominal U/S then PD was done for them according to their indications. The study showed that male was 53% with the age between 13 and 87 years while the female was 47% with the age between 12 and 91 years. Diabetes mellitus (DM) and hypertension (HT) were the most common cause of CRF. The outcome was: 30%complete improvement, 21% partial improvement, 26% less responsive and 23% died. In the last months of my study there was significant improvement. Inconclusion; DM and HT were the most common causes of CRF respectively; however obstructive uropathy had a notable ratio. There was no significant difference regarding sex. The outcome of PD was poor early in my study with significant improvements later.

scholarly journals GRANTING OF EDUCATION STRUCTURED NUTRITION AND ELECTROLYTE (ESNE) ON CHANGING INTERDIALYTIC WEIGHT GAIN IN CHRONIC CALCULATION FAILURE PATIENTS

2019 ◽  
Vol 3 (2) ◽  
pp. 89-99
Author(s):  
Lutfi Wahyuni ◽  
Ika Ainur Rofiah ◽  
Mochammad Achwandi
Keyword(s):  
Chronic Kidney Disease ◽  
Renal Failure ◽  
Weight Gain ◽  
Chronic Renal Failure ◽  
Kidney Disease ◽  
Kidney Function ◽  
The Body ◽  
Artificial Kidney ◽  
Fluid Restriction ◽  
Interdialytic Weight Gain

ABSTRACT   GRANTING OF EDUCATION STRUCTURED NUTRITION AND ELECTROLYTE (ESNE) ON CHANGING INTERDIALYTIC WEIGHT GAIN IN CHRONIC CALCULATION FAILURE PATIENTS By Lutfi Wahyuni, Ika Ainur rofiah, Mochammad Achwandi Chronic kidney disease is a condition when kidney function begins to decline gradually. The condition of the decline in kidney function occurs due to many factors, one of which is because the kidney damage that has occurred intensely for many years. Patients with chronic renal failure need a management or hemodialysis therapy, which is the cleansing process of blood from waste substances, through a screening process outside the body using an artificial kidney in the form of a dialysis machine. Hemodialysis therapy is needed in the management of patients with chronic renal failure who cannot be treated again (terminal). The success of hemodialysis is based on various elements, one of which is compliance with fluid restrictions. Limitation of fluid intake in patients with chronic renal failure is very important. The provision of structured education can be given to patients with chronic kidney failure who are undergoing hemodialysis therapy. Education structured nutrition and electrolyte (ESNE) is a structured health education on nutrition and electrolyte management for chronic renal failure patients undergoing hemodialysis. ESNE is done to improve patients' understanding of diet and electrolyte compliance to prevent an increase in IDWG and to improve patient compliance with fluid restrictions. The stages of service activities that have been carried out are to explain fluid requirements and fluid restriction in patients with chronic renal failure using the Education structured nutrition and electrolyte (ESNE) method, the next recourse is an evaluation after continuous or ESNE administration of respondents given treatment and respondents who were not treated. Keywords: Diet, Chronic Kidney Disease, Hemodialysis 

scholarly journals Monitoring Nilai Kritis Tekanan Sistolik Dan Diastolik Pada Asuhan Keperawatan Gagal Ginjal Kronik Yang Dilakukan Hemodialisis Jenis Arteriovena Shunt Cimino Dan Akses Femoral Cephalica

2017 ◽  
Vol 6 (1) ◽  
Author(s):  
Martono Martono
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Design Research ◽  
Diastolic Pressure ◽  
Systolic Pressure ◽  
The Body ◽  
Dialysis Access ◽  
Cross Sectional ◽  
Femoral Access ◽  
Av Shunt

Abstract: Systolic Pressure, Diastolic, Hemodialysis. Renal function at a more serious stage of the remnants of the metabolism could not be removed from the body, besides that, however, the kidneys can no longer change K / H for Na that resulted in an increase in the amount of potassium that machine that later can be triggered the interruption the heart. Hemodialysis is one of the alternative solutions that can be done when the kidneys experiencing the inability to mengekresikan debris from the remnants of the metabolism of the body. This research aims to clarify the picture changes critical value systolic pressure and diastolic pressure that done arteriovenous Cimino shunt type of hemodialysis and femoral access cephalic nursing nursery on chronic renal failure. This is the explanatory research design research with cross-sectional approach. A sample of this research is to patients with chronic renal failure undergoing hemodialysis which numbered 44 samples with sampling techniques using purposive sampling. This research statistics tests using descriptive test with the level of the significance of 95 %. The results of the study showed that the patients who performed hemodialysis aged candidates are age ≥51 about 59 percent and the age of the youngest 29 years and oldest 77 years, which dominated gender male.57 percent patients who do good hemodialysis AV Shunt or dialysis access Cephalica Femoral most no change in systolic pressure and diastolic pressure or settled.

scholarly journals Quality of life of patients undergoing hemodialysis

2017 ◽  
Vol 3 (1) ◽  
pp. 61
Author(s):  
Georgia Garofyllou ◽  
Martha Kelesi ◽  
Georgia Gerogianni ◽  
Konstantinos Tsaras ◽  
Georgia Fasoi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Chronic Hemodialysis ◽  
World Health ◽  
Dialysis Unit ◽  
Holistic Treatment ◽  
Study Results ◽  
The Impact

Introduction: Chronic Renal Failure (CRF) is a chronic disease, which has a negative impact on the quality of patients’ life. The study of factors affecting the quality of life of these patients is necessary to investigate the impact of the disease in a biological, psychological and social level.Aim: The purpose of this research study was to investigate the satisfaction of patients undergoing chronic hemodialysis and their perceptions of their quality of life.Material and Method: The study sample consisted of patients undergoing chronic hemodialysis at a Dialysis Unit in Athens. The study lasted from January 2016 to March 2016. To measure the health related quality of patients’ life, the Greek version of the questionnaire WHOQOL-BREF of the World Health Organization was used. The completion of the questionnaires was made by the method of the structured interview. A total of 70 questionnaires were completed.Results: According to the study results, most of the patients considered the quality of their life as good (48.6%), while the 8.5% described it as bad or very bad. The lowest satisfaction rates associated with issues of physical health and independence with mean (12.89 ± 2.23) and the highest with social relations (14.68 ± 1.50).Conclusion: The effect of Chronic Renal Failure on the physical, psychological and social background of patients on dialysis is an essential factor in creating a tailor-made holistic treatment program, adjusted to the specific needs of each patient.

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