scholarly journals One-year Clinical Results of Restorations Using a Novel Self-adhesive Composite Hybrid

2021 ◽  
Author(s):  
Andreas Rathke ◽  
Frank Pfefferkorn ◽  
Michael McGuire ◽  
Rick Heard ◽  
Rainer Seemann
Keyword(s):  
Clinical Results ◽  
The United States ◽  
Class Ii ◽  
Class I ◽  
Research Network ◽  
Class V ◽  
Dental Practitioners ◽  
Practice Based Research ◽  
Dual Curing ◽  
One Year

Abstract This prospective study assessed the dual-curing self-adhesive composite hybrid Surefil one. The restorations were placed and reviewed by dental practitioners who are members of a practice-based research network in the United States. Seven practitioners filled 60 cavities (20 class I, 19 class II and 21 class V) in 41 patients with Surefil one without adhesive, according to the manufacturer’s instructions. The restorations were evaluated using modified rating criteria at baseline and after 3 months and 1 year. Patients were also contacted to report postoperative hypersensitivity 1 to 4 weeks after placement. Recall rates were 98% after 3 months and 82% after 1 year. The only patient that showed moderate hypersensitvity after 1 year had previously reported symptoms that were unlikely associated to the class I molar restoration. One class II restoration in a broken maxillary molar was partially lost. The remaining 48 restorations were found to be in clinically acceptable condition resulting in an annual failure rate of 2%. The lowest number of acceptable scores (88%) was for color match. Self-adhesive composite hybrid restorations showed promising results in stress-bearing class I and II as well as non-retentive class V cavities at 1-year recall.

Mild and Severe Obesity Reduce the Effectiveness of Lumbar Fusions: 1-Year Patient-Reported Outcomes in 8171 Patients

Neurosurgery ◽  
2020 ◽  
Author(s):  
Graham Mulvaney ◽  
Olivia M Rice ◽  
Vincent Rossi ◽  
David Peters ◽  
Mark Smith ◽  
...  
Keyword(s):  
Risk Factor ◽  
Surgical Complications ◽  
Surgical Complication ◽  
Lumbar Fusion ◽  
Class Ii ◽  
Class I ◽  
Class Iii ◽  
Class I Obesity ◽  
Patient Reported ◽  
One Year

Abstract BACKGROUND Elevated body mass index (BMI) is a well-known risk factor for surgical complications in lumbar surgery. However, its effect on surgical effectiveness independent of surgical complications is unclear. OBJECTIVE To determine increasing BMI’s effect on functional outcomes following lumbar fusion surgery, independent of surgical complications. METHODS We retrospectively analyzed a prospectively built, patient-reported, quality of life registry representing 75 hospital systems. We evaluated 1- to 3-level elective lumbar fusions. Patients who experienced surgical complications were excluded. A stepwise multivariate regression model assessed factors independently associated with 1-yr Oswestry Disability Index (ODI), preop to 1-yr ODI change, and achievement of minimal clinically important difference (MCID). RESULTS A total of 8171 patients met inclusion criteria: 2435 with class I obesity (BMI 30-35 kg/m2), 1328 with class II (35-40 kg/m2), and 760 with class III (≥40 kg/m2). Increasing BMI was independently associated with worse 12-mo ODI (t = 8.005, P < .001) and decreased likelihood of achieving MCID (odds ratio [OR] = 0.977, P < .001). One year after surgery, mean ODI, ODI change, and percentage achieving MCID worsened with class I, class II, and class III vs nonobese cohorts (P < .001) in stepwise fashion. CONCLUSION Increasing BMI is associated with decreased effectiveness of 1- to 3-level elective lumbar fusion, despite absence of surgical complications. BMI ≥ 30 kg/m2 is, therefore, a risk factor for both surgical complication and reduced benefit from lumbar fusion.

scholarly journals Symptom changes and crack progression in untreated cracked teeth: One-year findings from the National Dental Practice-Based Research Network

2020 ◽  
Vol 93 ◽  
pp. 103269 ◽  
Author(s):  
Thomas J. Hilton ◽  
Ellen Funkhouser ◽  
Jack L. Ferracane ◽  
Gregg H. Gilbert ◽  
Valeria V. Gordan ◽  
...  
Keyword(s):  
Research Network ◽  
Dental Practice ◽  
Practice Based Research ◽  
Crack Progression ◽  
One Year ◽  
Symptom Changes

Morphology classification of circulating tumor cells could be a predictor of recurrent disease in patients with non-small cell lung cancer after surgery.

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e15530-e15530
Author(s):  
Yun Wu ◽  
Yuxu Niu ◽  
Fanzhen Lv ◽  
Wen Gao ◽  
Xiaoyong Shen
Keyword(s):  
Lung Cancer ◽  
Recurrent Disease ◽  
Class Ii ◽  
Class I ◽  
Class Iii ◽  
Class V ◽  
Lung Cancer Patients ◽  
Increased Risk ◽  
Class Iv

e15530 Background: CTCs have been widely used in monitoring the efficacy and prognosis of lung cancer. However, CTCs number count alone cannot accurately predict the recurrent disease in patients. In this study, we investigate whether the morphology classification of CTCs could be as a prognostic marker for increased risk of recurrence after surgery. Methods: In this study, 105 lung cancer patients (median age 68y) who underwent surgery were prospectively enrolled in this study. Samples were obtained before, after, and serially up to 24 months after surgery. CTCs were collected and morphology classified by utilizing a CTC test workflow which uses negative enrichment and immunofluorescence methods to capture and identify CTCs from blood sample. Captured CTCs (epithelial type) were screened with a customized imaging analysis pipeline, a cytological profile of each CTC was created, including cell size, shape, fluorescent intensity and texture etc. Results: The CTC detection rate was 78.1% (78 of 105) prior to surgery, and a total of 726 CTCs were enumerated. Median CTC count number was 3. 5 classes of CTCs with distinct morphological features were observed in lung cancer patients’ CTC tests, briefly, CTC class I and class II possessed large nuclei but relatively lower epithelial expression level, CTC class III, IV, V possessed small nuclei but relatively higher epithelial expression level, CTC class III possessed irregular shaped nuclei, CTC class V possessed relatively lower nuclei/cytoplasm ratio. Class III accounted for the highest proportion of captured CTCs III, about 35.5% with Class I 14.8%, Class II 15.3%,Class IV 17.8% and Class 5 16.6%. Postoperative recurrence and metastasis were observed in 16 patients. CTCs positive were found in 14 patients (87.5%). 145 CTCs were collected, Median CTC count number was 3,Cluster III accounted for 47.3%, with Class I 11.8%,Class II 13.3%,Class IV 14.5% and Class V 11.8%; Patients with Cluster 3 dominant were associated with increased risk of local recurrence ( p < 0.05) and distant metastasis ( p < 0.05). Conclusions: Small and irregular nuclei CTC is significant associated with increased risk of recurrence disease. Morphology Classification of circulating tumor cells is feasible in monitoring the recurrence of disease and may potentially identify the patients who may benefit from further therapy.

A One-Year Clinical Evaluation of a High-Viscosity Glass Ionomer Cement in Primary Molars

2006 ◽  
Vol 7 (1) ◽  
pp. 71-78 ◽  
Author(s):  
Yucel Yilmaz ◽  
Özge Eyuboglu ◽  
Mutlu Elcin Kocogullari ◽  
Nihal Belduz
Keyword(s):  
Clinical Evaluation ◽  
Glass Ionomer Cement ◽  
Class Ii ◽  
High Viscosity ◽  
Class I ◽  
Primary Molars ◽  
Glass Ionomer ◽  
Significant Difference ◽  
One Year ◽  
Ionomer Cement

Abstract In this study one-year clinical results of high-viscosity glass ionomer cement (GIC) (Fuji IX, A3, GC, Japan) were determined in class I and class II restorations in 68 primary molars with occlusal or approximal caries. Following caries removal and cavity preparation, the teeth were restored with Fuji IX. The restorations were evaluated according to the U.S. Public Health Service's (USPHS) criteria at the end of one year. Statistical analyses of the data obtained were analyzed using the X2 test. The evaluations showed no statistically significant difference between class I and class II restorations in terms of the color mismatch, anatomic form, marginal adaptation, and secondary caries (P>0.05), but they were statistically significant with regard to cavosurface marginal discoloration (P<0.05). At the end of one year, the success rate of the class I and class II restorations of the primary molars restored with Fuji IX was 94%. Citation Yilmaz Y, Eyuboglu Ö, Kocogullari ME, Belduz M. A One-Year Clinical Evaluation of a High-Viscosity Glass Ionomer Cement in Primary Molars. J Contemp Dent Pract 2006 February;(7)1:071-078.

scholarly journals Clinical Evaluation of Resin-Based Composites in Posterior Restorations: 12-Month Results

2010 ◽  
Vol 04 (01) ◽  
pp. 057-065 ◽  
Author(s):  
Cigdem Celik ◽  
Neslihan Arhun ◽  
Kivanc Yamanel
Keyword(s):  
Clinical Performance ◽  
Clinical Results ◽  
Class Ii ◽  
Class I ◽  
Chi Square ◽  
Exact Test ◽  
Usphs Criteria ◽  
Nanohybrid Composite

ABSTRACTObjectives: The purpose of this study was to evaluate and compare the 12 month clinical performances of two different posterior composites in Class I and Class II restorations.Methods: Thirty-one patients (10 male, 21 female) were recruited into the study. A total of 82 Class I and Class II cavities were restored with either a nanohybrid composite (Grandio) or a low-shrinkage composite (Quixfil), using their self etch adhesives (Futura Bond and Xeno III) according to manufacturers’ instructions. The restorations were clinically evaluated 1 week after placement as baseline, and after 6 and 12 months post-operatively using modified USPHS criteria by two previously calibrated operators. Statistical analysis were performed using Pearson Chi-square and Fisher’s Exact Test (P<.05).Results: All patients attended the 12-month recall. Lack of retention was not observed in any of the restorations. With respect to color match, marginal adaptation, secondary caries and surface texture, no significant differences were found between two restorative materials tested after 12 months (P>.05). None of the restorations had marginal discoloration and anatomic form loss on the 12 month follow-up. Restorations did not exhibit post-operative sensitivity at any evaluation period.Conclusions: Clinical assessment of nanohybrid (Grandio) and low-shrinkage posterior composite (Quixfil) exhibited good clinical results with predominating alpha scores after 12 months. However; further evaluations are necessary for the long-term clinical performance of these materials. (Eur J Dent 2010;4:57-65)

scholarly journals Phylogenetic Diversity among Low-Virulence Newcastle Disease Viruses from Waterfowl and Shorebirds and Comparison of Genotype Distributions to Those of Poultry-Origin Isolates

2007 ◽  
Vol 81 (22) ◽  
pp. 12641-12653 ◽  
Author(s):  
L. Mia Kim ◽  
Daniel J. King ◽  
Phillip E. Curry ◽  
David L. Suarez ◽  
David E. Swayne ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Newcastle Disease ◽  
Bird Species ◽  
The United States ◽  
Class Ii ◽  
Genomic Diversity ◽  
Class I ◽  
Diagnostic Tools ◽  
Death Time ◽  
Matrix Gene

ABSTRACT Low-virulence Newcastle disease viruses (loNDV) are frequently recovered from wild bird species, but little is known about their distribution, genetic diversity, or potential to cause disease in poultry. NDV isolates recovered from cloacal samples of apparently healthy waterfowl and shorebirds (WS) in the United States during 1986 to 2005 were examined for genomic diversity and their potential for virulence (n = 249). In addition 19 loNDV isolates from U.S. live bird markets (LBMs) were analyzed and found to be genetically distinct from NDV used in live vaccines but related to WS-origin NDV. Phylogenetic analysis of the fusion protein identified nine novel genotypes among the class I NDV, and new genomic subgroups were identified among genotypes I and II of the class II viruses. The WS-origin viruses exhibited broad genetic and antigenic diversity, and some WS genotypes displayed a closer phylogenetic relationship to LBM-origin NDV. All NDV were predicted to be lentogenic based upon sequencing of the fusion cleavage site, intracerebral pathogenicity index, or mean death time in embryo assays. The USDA real-time reverse transcription-PCR assay, which targets the matrix gene, identified nearly all of the class II NDV tested but failed to detect class I viruses from both LBM and WS. The close phylogenetic proximity of some WS and LBM loNDV suggests that viral transmission may occur among wild birds and poultry; however, these events may occur unnoticed due to the broad genetic diversity of loNDV, the lentogenic presentation in birds, and the limitations of current rapid diagnostic tools.

scholarly journals New Zealand needs a Practice Based Research Network

2016 ◽  
Vol 8 (1) ◽  
pp. 9 ◽  
Author(s):  
Sharon Leitch
Keyword(s):  
New Zealand ◽  
Low Cost ◽  
Data Extraction ◽  
Research Capacity ◽  
The United States ◽  
Healthcare Research ◽  
Research Network ◽  
Practice Research ◽  
Research Information ◽  
Practice Based Research

ABSTRACT Practice Based Research Networks (PBRNs) are groups of general practices collaborating to produce research. Contemporary New Zealand health information technology systems are ideal for electronic data extraction for PBRN research. Stakeholders have a valuable, but typically underutilised, part to play in research. Development of an e-participation platform will facilitate stakeholder engagement. New Zealand is in a unique position to create an innovative, low cost, stakeholder-engaged PBRN. This type of PBRN would offer unparalleled research opportunities, and would strengthen New Zealand’s general practice research capacity. The more research information we have based on our New Zealand population, the more appropriate care we can provide. Establishing a stakeholder-engaged PBRN in New Zealand will promote and support transformational change within our health system. In June 2015 I had the privilege of attending the annual Practice Based Research Network (PBRN) Conference held in Bethesda, near Washington D.C. The conference is hosted by the North American Primary Care Research Group and the United States (US) Agency for Healthcare Research and Quality. In this article I draw on the knowledge I gained at that conference and discuss its translation to New Zealand.

scholarly journals Clinical and Radiographic Evaluation of Compomer and Composite used for Restoring Primary Teeth

2019 ◽  
Vol 26 (1) ◽  
pp. 37-49
Author(s):  
Omar A. El Meligy ◽  
Amani A. Al Tuwirqi
Keyword(s):  
Primary Teeth ◽  
Resin Composite ◽  
Class Ii ◽  
Class I ◽  
Radiographic Evaluation ◽  
Primary Molars ◽  
Tooth Structure ◽  
Patients Âgés ◽  
Group I ◽  
One Year

This study assessed different restorative materials in primary teeth over a one-year period. Sixty carious primary molars were selected from 30 patients; ages 5-10 years. Class I and II cavities were divided into four groups: Group I: 15 Class I cavities were restored with a compomer, Group II: 15 Class I cavities were restored with a resin composite, Group III: 15 Class II cavities were restored with a compomer and Group IV: 15 Class II cavities were restored with a resin composite. Each child had two teeth restored, one with compomer and the other with composite resin as control. Direct clinical and radiographic evaluations were performed by one examiner after 24 hours, 6- and 12-months. Indirect clinical evaluations were performed using a Scanning Electron Microscope after 24 hours and 12-months periodically. Clinical and radiographic evaluations revealed no significant differences between the compomer and resin composite at 6- and 12-months. Indirect clinical evaluation showed good marginal interfaces between the restorations and the tooth structure throughout the evaluation periods. Both materials presented significant clinical and radiographic performances in Class I and II restorations of primary molars after one year.

scholarly journals Practice-Based Research Networks and Massage Therapy: a Scoping Review

2020 ◽  
Vol 13 (4) ◽  
pp. 25-34
Author(s):  
Samantha Zabel, MA ◽  
Niki Munk, PhD, LMT
Keyword(s):  
Scientific Evidence ◽  
Massage Therapy ◽  
Professional Associations ◽  
The United States ◽  
Database Search ◽  
The Body ◽  
Research Network ◽  
Research Networks ◽  
Massage Therapist ◽  
Practice Based Research

Background: Practice-based research networks (PBRNs) are means to connect practitioners with researchers and increase the body of rigorous research. PBRNs have been used in medicine for decades, but efforts to create PBRNs in massage therapy (MT) are limited. Purpose: Examine and describe the amount of and nature of MT-related publications derived from PBRN-supported endeavors. Publication Selection: Databases: Scopus, CINAHL, PubMed, ClinicalKey, EMBASE, Google Scholar. Keywords: massage, massage therapy, practice-based research network, PBRN. Key items: publication year, operating PBRN, article type, study design, general theme, massage therapist involvement/MT application. Inclusion Criteria: studies conducted through a PBRN using MT/massage therapists as an investigated factor; articles/editorials focused on PBRN-related MT research. Results: Initial database search resulted in 444 records; 40 articles included in analysis from database search, PBRN website access, and PBRN staff contacts. Publication dates ranged from 2005 to 2019, with nearly all published since 2013. Nine PBRNs published 29 articles based on 20 studies and sub-studies as research papers (n=21) or poster/oral presentation abstracts (n=8), and articles discussing the need for PBRNs in MT (n=8). Most research studies were conducted as surveys (n=21), examining practice characteristics (n=9) and patient perspectives/utilization (n=7). Three articles discussing PBRNs in MT were not connected to any specific PBRN. Conclusion: The PBRN model holds promise to further the field of MT, but implementation needs significant development. Promoting the creation and growth of massage-specific PBRNs should be a focus of professional associations and research institutions to expand the body of scientific evidence supporting MT. While the United States has had the most PBRN-related research efforts, a sustainable implementation model is not evident as highlighted by inactivity from US-based PBRNs after initial productivity. An Australian PBRN may serve as a needed sustainability model for massage-related PBRNs in the US if their productivity trajectory continues.

scholarly journals Effects of orthodontic treatment after adenoidectomy on jaw relations in the sagittal plane

2005 ◽  
Vol 62 (4) ◽  
pp. 287-292 ◽  
Author(s):  
Jasmina Milic
Keyword(s):  
Orthodontic Treatment ◽  
Treatment Effects ◽  
Sagittal Plane ◽  
Class Ii ◽  
Open Bite ◽  
Class I ◽  
Group 2 ◽  
One Year ◽  
Group 1

Aim. To evaluate the orthodontic treatment effects, performed immediately after adenoidectomy, on lips relation, overjet and class (Angle). Methods. Three groups of patients, aged 6?17 years, were observed: group K - patients with oral respiration caused by adenoidal enlargement; group 1 - patients with adenoidectomy performed five and more years previously; group 2 - patients with one year of orthodontic treatment performed immediately after adenoidectomy. Lips and overjet status and class (Angle) was measured in the examined patients. Results. In all of the three examined groups, there was a statistically highly significant increase (p<0.01) of competent lips. In the patients of group K, the overjet values ranged from 1 mm up to 12 mm where 90% of them had overjet > 4 mm and 6% < 1 mm. The front open bite, low overbite and reversed overjet was found in the patients with low overjet in this group, as well. Overjet values in the patients of group 1 ranged from -2 mm up to 12 mm where 86% had overjet > 4 mm and 10% < 1 mm. Significantly higher increase (p<0.01) of overjet values (1?4 mm in 94% of patients) was observed in the patients of group 2 in comparison to the values found in the patients from groups 0 and 1. Class II (Angle) was recorded in 81% of the patients in group 0, and 79% in group 1, while class I (Angle) was observed 100% only in the patients of group 2. Conclusion. Orthodontic treatment immediately after adenoidectomy was necessary for achieving the competition lips relation, normal overjet and class I (Angle).

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