Helicobacter pylori infection and its correlates among the patients of peptic perforation and gastric carcinoma

2020 ◽  
Author(s):  
Subhendu Bikas Saha ◽  
Sabyasachi Bakshi ◽  
Tapas Mandal

Abstract Background: Presence of H. pylori infection was found associated with peptic perforation and gastric carcinoma. Present study tried to estimate the prevalence of H. pylori infection in those patients and to find out the correlates of H. pylori infection.Methods: After matching the inclusion and exclusion criteria, all cases of diagnosed peptic perforation and gastric carcinoma were taken for this prospective, single center, observational study.Results: Among the study population, gastric carcinoma was found in higher age group; whereas peptic perforation was found in lower age group; male and female ratio was 2:1 in both groups of patient. Laborer and housewives were mostly affected in both cases. Gastric carcinoma was more prevalent in urban residents, opposite was seen in peptic perforation. Most patients in two groups had no previous co-morbid condition. Use of NSAIDs was found in high frequency in both groups. Most of the patients were chronic alcoholic and chronic smoker, and most of them had history of taking spicy foods more than twice in a week.Conclusions: H. pylori infection was found in high frequency in both group of patients, and it was higher in peptic perforation. The study establishes the association of H. pylori with the gastric carcinoma and peptic perforation.

2020 ◽  
Vol 7 (5) ◽  
pp. 1518
Author(s):  
Subhendu Bikas Saha ◽  
Sabyasachi Bakshi ◽  
Tapas Mandal

Background: Presence of H. pylori infection was found associated with peptic perforation and gastric carcinoma. Present study tried to estimate the prevalence of H. pylori infection in those patients and to find out the correlates of H. pylori infection.Methods: After matching the inclusion and exclusion criteria, all cases of diagnosed peptic perforation and gastric carcinoma were taken for this prospective, single center, observational study.Results: Among the study population, gastric carcinoma was found in higher age group; whereas peptic perforation was found in lower age group; male and female ratio was 2:1 in both groups of patient. Laborer and housewives were mostly affected in both cases. Gastric carcinoma was more prevalent in urban residents, opposite was seen in peptic perforation. Most patients in two groups had no previous co-morbid condition. Use of NSAIDs was found in high frequency in both groups. Most of the patients were chronic alcoholic and chronic smoker, and most of them had history of taking spicy foods more than twice in a week.Conclusions: H. pylori infection was found in high frequency in both group of patients, and it was higher in peptic perforation. The study establishes the association of H. pylori with the gastric carcinoma and peptic perforation.


2020 ◽  
Vol 7 (11) ◽  
pp. 1619
Author(s):  
Solaiman Mia ◽  
Goutam Kumar Acherjya ◽  
Paritosh Kumar Ghosh ◽  
Mahfuzur Rahman ◽  
Quazi S. Islam

Background: We aimed to find out the age-related differences in risk profile among Bangladeshi adults suffering from stable angina.Methods: An observational study was conducted in three different districts in Bangladesh (Feni, Noakhali and Chandpur) through the medical camps during the period from 1st February 2018 to 31st July 2018. Data of 764 stable angina patients was analysed.Results: The male to female ratio in both groups was 4:1. The mean age of the study population in younger group was 34.0±5.2 years and in older group 57.0±6.3 years. Smokers were more in younger group (70.0% vs. 46.0%; p=0.032). Hypertension was less in the younger group (38.0% vs. 58.0%) (p=0.045). Presence of diabetes was higher in the older age group (34.0% vs. 4.0%) (p=0.001). The total cholesterol was higher in older group (182.9±33.1) vs. (171.1±24.8 mg/dl) (p=0.047). 68% of patients of older group and 38% of younger group had stenosis in left anterior descending artery (p=0.003). The involvement of left circumflex and right coronary artery in older age group were higher (56% and 66% respectively) than those in younger group (36% and 40% respectively) (p=0.045 and p=0.009). Patients had multiple risk factors like hypertension, family history of cardiovascular disease, smoking and ischemic heart disease (IHD).Conclusions: This study found that the incidence of IHD is very among the district-level diabetic patients of Bangladesh and this incidence increases with the rise of age.


Author(s):  
Aastha N. Patel ◽  
Shankar S. Ganvit

 Background: An occupational hazard is a hazard experienced in the workplace. This includes many types of hazards like chemical hazards, biological hazards, psychosocial hazards and physical hazards. Occupational ocular trauma holds significant proportion of visual morbidity worldwide. This can be prevented with the use of proper protective eyewear and strict compliance. This survey was conducted to study occupational related ocular hazard in our tertiary health care system hospital having patients involved in various occupations.Methods: A total of 90 occupational ocular injuries were recorded during study period. The age group of the patients to be studied was between 20 to 60 years. Brief history of present complaints, detailed clinical history and occupation history as like type of work, working environment, place, working hours was recorded. Required ophthalmological check-up was done. All valid responses were tabulated and analysed. Appropriate treatment was given.Results: Our study showed that majority (85.6%) of patients were not wearing protective eye equipment. Male to female ratio was approximately 3:1. Major age group affected was between 31-40 years (41.1%). Welders (40%) were more prone to injury occupation wise.Conclusions: Occupational eye injury is often severe and it contributes to significant loss. Incompliance of appropriate protective eye wear can lead to potential eye damage and permanent blindness.


Author(s):  
Nayanna Karodpati ◽  
Vinayak Kuradagi ◽  
Paresh Chavan ◽  
Rishikesh Pawar ◽  
Lakshmi Sravya Kakollu

<p><strong>Background:</strong> Deep neck space infections are usually due to excessive growth of normal flora, mostly of polymicrobial in origin. Patients present acutely with complaints of, throat and neck pain, raised body temperature. The clinical presentation depends on the deep neck space affected.<strong></strong></p><p><strong>Methods:</strong>  Current study was carried out in 25 patients who were diagnosed to have various deep neck infections</p><p><strong>Results:</strong> It was observed that the maximum number of cases were seen in the age group of 31-40 at 28%, followed by 21-30 age group at 20%, 16% each between 41-50 years and above 60 years. The male to female ratio is 1:0.78. The most common presenting complaints included fever (24 patients; 96%) and dysphagia (18 patients; 72%). 13 patients (52%) had associated systemic disease, 5 patients (20%) had history of diabetes mellitus and were on irregular treatment, 4 patients (16%) was on treatment for hypertensive. The most common infection was Ludwig’s angina seen in 13 patients (52%), followed by peritonsillar abscess 4 patients (16%). Out of 25 patients, 20 (80%) cases were treated successfully by incision and drainage. No growth was observed in 32% of the patients.</p><p><strong>Conclusions:</strong> Early diagnosis of deep neck space infection based on symptoms in susceptible patients is advisable to prevent complications and early recovery.</p>


2018 ◽  
Vol 5 (2) ◽  
pp. 363 ◽  
Author(s):  
Mary James ◽  
Poornima K. N. ◽  
Praveen Jacob Ninan

Background: Pediatricians often encounter children with heart murmurs during routine follow up visits or while assessment of intercurrent illness. Clinical differentiation between pathologic and innocent murmurs would be important. It is important to identify those children who need further evaluation. The aim of the study was to evaluate whether Nadas criteria can be applied as a screening test to decide on further workup.Methods: This was a prospective descriptive study done in Government T. D. Medical College, Alappuzha over a period of 12 months from July 2013 to June 2014. All children in the age group one month to 12 years, attending the outpatient department were screened for presence of murmur of grade 2 and more. They were further evaluated carefully. They were also studied for association of variables like maternal age, birthweight, dysmorphism and family history of heart disease. Nadas criteria was then applied to the study population. A score of 2 and 1 were given to major and minor criteria respectively.Results: 3070 children were screened. 150 children were detected to have murmur of grade2 and more.66 children were detected to have a structural heart disease by an echo study.74% of the study population in the age group <1 year had a heart disease.8 out of 78 children with a Nadas score of 1 and 10 out of 24 with a score of 2 had a heart disease. All with a score 3 and more had congenital heart disease (CHD).Conclusions: Nadas criteria can be used as screening test with a sensitivity of 87% and specificity of 83%. 


Author(s):  
Dayanand Raikar ◽  
Mohammed Waseem Javed ◽  
Anant Arunrao Takalkar

<p class="abstract"><strong>Background:</strong> Facial pigmentary disorders are a group of heterogenous entities, sharing a common clinical feature of altered pigmentation of the face and thus easily visible cosmetic disfigurement. Although the increased melanin provides protection from harmful effects of UV radiation, including photodamage and skin cancers, it also makes darkly pigmented skin more vulnerable to post-inflammatory dyspigmentation. The importance of these disorders is growing, as they form the major percentage of dermatology consultations. The objective of the study was to assess the clinical profile of patients with facial hyperpigmentation.</p><p class="abstract"><strong>Methods:</strong> The present cross-sectional hospital based observational study was conducted at Dermatology Department of during the period of June 2017 to December 2017 including patients with diagnosis of facial hyperpigmentation. Data analysed with SPSS 24 version.<strong></strong></p><p class="abstract"><strong>Results:</strong> 29% were from 21 to 30 years age group followed by 25% from 31 to 40 years age group. Mean age of the study population was 28.4±11.8 years. 76% were female patients. Commonly observed facial hyperpigmentation type was melasma in our study i.e. 46%. It is followed by post inflammatory hyperpigmentation (PIH) in 16% and ephilides in 8%. Rehl's melanosis and drug induced melanosis was seen in 7% each of the patients. Ephilides, Rehl's melanosis and drug induced was seen in 7% each of the patients. Family history of pigmentaory disorder was found in melasma, PIH and ephilides in our study.</p><p class="abstract"><strong>Conclusions:</strong> Commonly reported age group was 20-40 with female preponderance. Commonly observed facial hyperpigmentation type was melasma (46%), PIH (16%) and ephilides (8%).</p>


2015 ◽  
Vol 4 (2) ◽  
Author(s):  
Putri Yuriandini Yulsam ◽  
Fadil Oenzil ◽  
Efrida Efrida

AbstrakPenyakit jantung koroner (PJK) merupakan salah satu penyakit non-infeksi yang menjadi sorotan dunia. Hal ini terkait dengan adanya perubahan gaya hidup seiring dengan perkembangan zaman. WHO pada tahun 2008 memperkirakan 17,3 juta jiwa meninggal akibat penyakit kardiovaskular, 7,3 juta jiwa diakibatkan oleh PJK dan 6,2 juta akibat strok. Tujuan penelitian ini adalah untuk mengetahui gambaran insidens riwayat hipertensi dan diabetes melitus pada pasien PJK di RS. Dr. M. Djamil Padang. Ini merupakan penelitian deskriptif dengan rancangan potong lintang yang dilakukan di Bagian Rekam Medik RS. Dr. M. Djamil Padang yang berlangsung dari Februari 2012 sampai Maret 2013. Populasi penelitian sebanyak 184 rekam medik, tetapi yang memenuhi kriteria inklusi dan eksklusi sebanyak 124 sampel Pengolahan data dilakukan secara manual dan ditampilkan dalam bentuk tabel distribusi frekuensi. Hasil penelitian menunjukkan distribusi frekuensi pasien PJK berdasarkan usia yaitu kelompok usia 51-56 tahun sebesar 30,64% dan sebagian besar adalah laki-laki (75%). Prevalensi riwayat hipertensi pada pasien PJK didapatkan sebesar 46,77%, sedangkan riwayat diabetes melitus sebesar 10,48%.Kata kunci: penyakit jantung koroner, hipertensi, diabetes mellitus AbstractCoronary heart disease (CHD) is one of the non-infectious disease that become the world spotlight. It is associated with a change in lifestyle paralel to the era development. WHO in 2008 estimated that 17,3 million people died from cardiovascular disease, 7,3 million attributable to CHD, and 6,2 million died due to stroke. The objective of this study was to describe the incident history of hypertension and diabetes mellitus in patient with CHD in Dr. M. Djamil Hospital Padang. This was a descriptive study with cross sectional design which carried out in Medical Record of Dr. M. Djamil Hospital Padang from February 2012 until March 2013. The population in this study were 184 medical record, but the samples had the inclusion and exclusion criteria were 124 medical record. All data were processed and analysed by manually and then the data shown by frequency distribution table. The result showed the highest distribution of CHD patient based on age is in the age group of 51-56 years, and majority were male (75%). The prevalence of hipertension history in CHD patient is 46.77% while a history of diabetes mellitus is 10,48%.Keyword: coronary heart disease, hypertension, diabetes mellitus.


Author(s):  
J. Sushma ◽  
B. V. S. Kartheek ◽  
A. Bhagya Lakshmi

Background: Gastric cancer represents one of the most frequent neoplasias. Although its incidence decreased over the last few decades in industrialized countries, it still represents nowadays a major cause of death through cancer throughout the world. The purpose of this study was to identify clinicopathological parameters in gastric carcinoma.Methods: A total of 115 gastrectomy specimen received in 5 year period at a tertiary care center was analyzed. The clinical data was recorded. After fixing the specimen in 10% formal saline for 24 hours the gross appearance of the specimen was studied. The gross findings were recorded following Borrmann classification. The tissue blocks were routinely processed and stained with H&E stain. The results were tabulated.Results: The prevalence of gastric carcinoma was 4.46%, with male: female ratio of 3:1 and mean age of 50years.The prevalence of carcinoma stomach was more common in rural areas and poor socio economic status. Sixty percent of patients who consumed mixed diet suffered from carcinoma and 82.8% had history of intake of alcohol. Carcinoma stomach was more common in A blood group. The tumor was more common in pyloric antrum (73.04%). According to Borrmann classification type II tumour was the commonest (66.09%) of the lesions. Commonest histological pattern was adenocarcinoma; intestinal type (86.72%).Conclusions: The prevalence of carcinoma stomach in the present study was 4.46%. High prevalence of gastric carcinoma was seen in patients with history of smoking, intake of alcohol and consumption of mixed diet. Carcinoma stomach was more common in A blood group followed by B blood group. Adenocarcinoma of intestinal type was the commonest.


2019 ◽  
Vol 16 (2) ◽  
pp. 60-64
Author(s):  
Tahmida Firdousi ◽  
Taslima Begum ◽  
Shimul Akter ◽  
Nur Mohammad

Background: Foetal weight detection can vary by examining clinically. Objective: The purpose of the present study was to see the variation of clinical foetal weight among the newborn infant. Methodology: This prospective cohort study was carried out in the Department of Obstetrics & Gynaecology at Rajshahi Medical Hospital, Rajshahi, Bangladesh from July 2012 to June 2014 for a period of 2(two) years. Pregnant women with known gestational age at term (38 to 40 weeks of pregnancy), singleton pregnancy with longitudinal lie were included in this study. The clinical estimation of foetal weight was done. Actual birth weights of babies were measured soon after their birth. This weight was measured within the first hour of life. They were weighed naked. Result: A total number of 245 pregnant women in term pregnancy were recruited as per inclusion and exclusion criteria. Majority of the women [91(37.1%)] belonged to the age group 25 to 29 years, 83 (33.9%) in the age group 19 to 24 years. Low Birth Weight was found 14(5.7%) cases in clinical examination and 15(6.0%) cases in actual cases. Normal birth weight was found 215(87.8%) cases and 221(90.3%) cases in clinical examination and actual weight respectively. The mean with SD of foetal weight among the study population were 3283.27±461.05 gm and 2936.20±456.71 gram in clinical examination and actual weight respectively (p < 0.05). Conclusion: In conclusion there is a significant variation of clinical estimation of foetal weight Journal of Science Foundation 2018;16(2):60-64


2017 ◽  
Vol 29 (2) ◽  
pp. 5-8
Author(s):  
Jahangir Alam Mazumder ◽  
Rafiqul Islam Sarker ◽  
AHM Delwar ◽  
Kamrunnahar

Ear foreign body is a common ENT emergency and a challenge also to otolaryngologist worldwide. Prompt and appropriate management of it can reduce the morbidity. An observational retrospective study of 148 cases of foreign body in the ear done in Comilla Medical College Hospital and two upazilla health complexes (Nangalkot and Chowddagram) of Bangladesh within the period of January 2014 to December 2014 to evaluate the nature, mode of presentation, technique of removal and outcome of it. Data were collected from hospital records including age, sex of patient and mode and time of presentation, nature of foreign body, management outcome and complication, and the result showed that children o funder 15 year age group were mostly affected (60%), among them highest incidence were in 5-10 year age group (25%) with male to female ratio 1:1.28. The most common foreign body was the seeds of various vegetables (25.67%) followed by plastic beads (18.24%) and cotton bud (15.54%), the right ear affected more (54%). Almost half of them (47.97%) presented with history of insertion of a foreign body and most of them (91.98%) were removed in OPD or emergency department under direct vision and remaining required general anesthesia. Despite a high proportion of cases managed in the office setting, complication rates were within acceptable level. It is inversely proportional to the skill of the personnel, number of attempts &availability of equipment. Key to successful outcome are prompt help by well-trained doctor and otolaryngological equipment set up.Medicine Today 2017 Vol.29(2): 5-8


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