scholarly journals The prevalence, distribution and impact of peripheral neuropathy among Danish patients with cancer – A population-based cross-sectional study.

2021 ◽  
Author(s):  
Sebastian Werngreen Nielsen ◽  
Christina H. Ruhlmann ◽  
Lise Eckhoff ◽  
Jørn Herrstedt ◽  
Susanne O. Dalton
Keyword(s):  
Peripheral Neuropathy ◽  
Population Based ◽  
Cross Sectional Study ◽  
Summary Score ◽  
Outpatient Services ◽  
Cross Sectional Survey ◽  
Related Factors ◽  
Cross Sectional ◽  
Eortc Qlq C30 ◽  
Eortc Qlq

Abstract Purpose: Prevalence of peripheral neuropathy (PN) has been studied in patients undergoing treatment with taxanes, platinums and vinca alkaloids. The prevalence is unknown in the general oncological cancer population, characterized by advanced age, comorbidities and heterogeneous treatments.Methods: A cross-sectional survey was administered to all adult patients, attending outpatient services at three Danish departments of oncology. The survey contained the EORTC-QLQ-C30, the EORTC-CIPN20, the GAD7 and PHQ9 questionnaires. A high PN symptom score was defined as a summary score ≥ 30 points on the CIPN20.Results: With an overall response rate of 83% (2839 patients), prevalence of PN was 17% overall, varying from 15 to 30% between diagnosis groups.Conclusion: Symptoms of PN are experienced widely across cancer groups in the oncology setting and symptoms are correlated with patient-related factors as living alone, various comorbidities, polypharmacy, and cannabis use.

scholarly journals Psychometric validation of the Moroccan version of the EORTC QLQ-C30 in colorectal Cancer patients: cross-sectional study and systematic literature review

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yacir El Alami ◽  
Hajar Essangri ◽  
Mohammed Anass Majbar ◽  
Saber Boutayeb ◽  
Said Benamr ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Discriminant Validity ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Related Quality ◽  
Eortc Qlq C30 ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients

Abstract Background Health-related quality of life is mainly impacted by colorectal cancer which justified the major importance addressed to the development and validation of assessment questionnaires. We aimed to assess the validity and reliability of the Moroccan Arabic Dialectal version of the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Core Questionnaire (QLQ-C30) in patients with colorectal cancer. Methods We conducted a cross-sectional study using the Moroccan version of the EORTC QLQ-C30 on colorectal cancer patients from the National Oncology Institute of Rabat, in the period from February 2015 to June 2017. The QLQ-C30 was administered to 120 patients. Statistical analysis included reliability, convergent, and discriminant validity as well as known-groups comparisons. Results In total, 120 patients with colorectal cancer were included in the study with 38 (32%) patients diagnosed with colon cancers. Eighty-two patients (68%) had rectal cancer, among which 29 (24%) patients with a stoma. The mean age of diagnosis was 54 years (+/− 13.3). The reliability and validity of the Arabic dialectal Moroccan version of the EORTC QLQ-C30 were satisfactory. [Cronbach’s alpha (α =0.74)]. All items accomplished the criteria for convergent and discriminant validity except for question number 5, which did not complete the minimum required correlation with its own scale (physical functioning). Patients with rectal cancer presented with bad Global health status and quality of life (GHS/QOL), emotional functioning as well as higher fatigue symptoms compared to patients with colon cancer. The difference between patients with and without stoma was significant for diarrhea and financial difficulty. Conclusions The Moroccan Arabic Dialectal version of the QLQ-C30 is a valid and reliable measure of health-related quality of life (HRQOL) in patients with colorectal cancer.

scholarly journals Self‐reported visual difficulties in Europe and related factors: a European population‐based cross‐sectional survey

2020 ◽  
Author(s):  
Nicolas Leveziel ◽  
Simon Marillet ◽  
Tasanee Braithwaite ◽  
Tunde Peto ◽  
Pierre Ingrand ◽  
...  
Keyword(s):  
Population Based ◽  
European Population ◽  
Cross Sectional Survey ◽  
Related Factors ◽  
Cross Sectional

scholarly journals Delays to diagnosis among people with severe mental illness in rural Vietnam, a population-based cross-sectional survey

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Trang Nguyen ◽  
Thach Tran ◽  
Sally Green ◽  
Arthur Hsueh ◽  
Tuan Tran ◽  
...  
Keyword(s):  
Mental Health ◽  
Mental Illness ◽  
Severe Mental Illness ◽  
Financial Burden ◽  
National Policy ◽  
Mental Health Program ◽  
Population Based ◽  
Cross Sectional Study ◽  
Cross Sectional Survey ◽  
Cross Sectional

Abstract Background People with severe mental illness (SMI) living in low and middle-income countries can experience extended delays to diagnosis, which hinder access to medical treatment. The aims of this study were to describe the interval to diagnosis among these people in rural Vietnam and its associated factors. Methods A population-based cross-sectional study was conducted among people with SMI in two provinces in Vietnam. The delay to diagnosis was defined as the time between the first abnormal behaviour being observed by family members and the formal diagnosis of psychosis. A multilevel linear regression was used to examine the factors associated with the delay to diagnosis. Results Among 404 people with SMI from 370 households, the median delay to diagnosis was 11.5 months (IQR 0–168.0). Overall, 53.7% had a delay to diagnosis of less than one year (95% CI: 48.81–58.54). The financial burden of these people on their families was nearly USD 470/year. After adjusting for other factors at individual and household levels, living in a Northern province; older age, and having psychotic diagnosis before the implementation of the National Community Mental Health program (2003) were associated with a delay of more than twelve months to diagnosis. Conclusions These data indicate that the implementation of a national policy for community-based care has been effective in reducing the delay to diagnosis in rural Vietnam. Therefore, there is a need for strengthening the program and mental health policies, focusing on public communication to improve mental health literacy and reduce stigma against SMI.

Public knowledge about dementia in South Korea: a community-based cross-sectional survey

2014 ◽  
Vol 27 (3) ◽  
pp. 463-469 ◽  
Author(s):  
Hyun-Ju Seo ◽  
Dong Young Lee ◽  
Mi Ra Sung
Keyword(s):  
South Korea ◽  
Quantitative Methods ◽  
The Elderly ◽  
Population Based ◽  
Cross Sectional Study ◽  
Public Knowledge ◽  
Cross Sectional Survey ◽  
Community Based ◽  
Cross Sectional ◽  
General Populations

ABSTRACTBackground:The highest increase in the prevalence of dementia in the elderly population is expected in South Korea than in any other country in the world. However, there is no assessment of the community-based general populations’ understanding of dementia in South Korea, in spite of the increasing burden of dementia. Thus, this study assessed the public knowledge about dementia.Methods:This is a population-based, cross-sectional study of 2,189 participants, aged 10 years or older, and living in Seoul, South Korea. A 12-item questionnaire with true/false responses was used to assess the knowledge about dementia from June to November 2011. The data obtained were analyzed using quantitative methods.Results:The mean score for the knowledge about dementia was 9.0 ± 2.1 points out of 12 points. More than half of the respondents (52.7%) reported that dementia is not treatable, and one-third of the participants did not know that Alzheimer's disease is the most common cause of dementia. The level of dementia knowledge was negatively associated with increasing age, and positively associated with higher education level.Conclusions:Our results suggest that although laypersons had a fair knowledge about dementia, further educational programs and campaigns are needed to improve knowledge about dementia, more focusing on elderly adults as the target audience and emphasizing the causes and treatments of dementia as educational contents.

scholarly journals Understanding determinants of unequal distribution of stillbirth in Tehran, Iran: a concentration index decomposition approach

BMJ Open ◽  
2017 ◽  
Vol 7 (5) ◽  
pp. e013644 ◽  
Author(s):  
Amir Almasi-Hashiani ◽  
Mahdi Sepidarkish ◽  
Saeid Safiri ◽  
Esmaeil Khedmati Morasae ◽  
Yahya Shadi ◽  
...  
Keyword(s):  
Concentration Index ◽  
Economic Status ◽  
Principal Component ◽  
Population Based ◽  
Cross Sectional Study ◽  
Related Factors ◽  
Negative Contribution ◽  
Cross Sectional ◽  
Unequal Distribution ◽  
Decomposition Approach

ObjectiveThe present inquiry set to determine the economic inequality in history of stillbirth and understanding determinants of unequal distribution of stillbirth in Tehran, Iran.MethodsA population-based cross-sectional study was conducted on 5170 pregnancies in Tehran, Iran, since 2015. Principal component analysis (PCA) was applied to measure the asset-based economic status. Concentration index was used to measure socioeconomic inequality in stillbirth and then decomposed into its determinants.ResultsThe concentration index and its 95% CI for stillbirth was −0.121 (−0.235 to −0.002). Decomposition of the concentration index showed that mother’s education (50%), mother’s occupation (30%), economic status (26%) and father’s age (12%) had the highest positive contributions to measured inequality in stillbirth history in Tehran. Mother’s age (17%) had the highest negative contribution to inequality.ConclusionsStillbirth is unequally distributed among Iranian women and is mostly concentrated among low economic status people. Mother-related factors had the highest positive and negative contributions to inequality, highlighting specific interventions for mothers to redress inequality.

QOLP-22. THE PSYCHO-ONCOLOGICAL BURDEN OF PATIENTS WITH AGGRESSIVE MENINGIOMA – RESULTS FROM A RETROSPECTIVE CROSS-SECTIONAL STUDY

2021 ◽  
Vol 23 (Supplement_6) ◽  
pp. vi187-vi187
Author(s):  
Christine Jungk ◽  
Madlen Raedel ◽  
Julia Mattern-Tremper ◽  
Rolf Warta ◽  
Christel Herold-Mende ◽  
...  
Keyword(s):  
Internal Control ◽  
Multivariate Regression Analysis ◽  
Extent Of Resection ◽  
Cross Sectional Study ◽  
Related Factors ◽  
Cross Sectional ◽  
Who Grade ◽  
Eortc Qlq ◽  
The Impact

Abstract Despite the perception of meningioma as a benign disease, up to 35% of patients experience a clinically aggressive course with debilitating treatment and poor outcome. In contrast to the growing interest in novel therapies, the impact on health-related quality of life (HRQoL) is still understudied. Here, we analysed the psycho-oncological burden of patients with aggressive meningioma. Our institutional cohort was searched for meningioma patients with surgery as first intervention and HRQoL was assessed retrospectively at one time point with standardized self-assessment questionnaires (HADS-D, EORTC-QLQ-C30). Aggressive meningioma was defined as WHO grade 2 or 3 or recurrence of a WHO grade 1 meningioma within 5 years after index surgery. Results were correlated with demographic, tumor- and treatment-related factors by multivariate linear regression and compared to internal control patients (WHO grade 1 meningioma, no recurrence within the first 5 years). 400 out of 653 patients returned the questionnaires (62%). Of those, 95 patients (24%) were classified as aggressive meningioma while 305 patients served as internal control. Patients with and without aggressive meningioma differed with regard to sex (p=0.019), age (p=0.015), extent of resection (p< 0.0001) and adjuvant radiotherapy (p< 0.0001) at index surgery and KPS at 1st follow-up (p=0.037). 34% and 24% of aggressive meningioma patients were screened positive on the anxiety and depression subscales of HADS-D as opposed to 33% and 23% of internal controls (not significant). Aggressive meningioma patients fared significantly worse on most of the function scales of QLQ-C30 (QL: p=0.004; PF: p=0.049; RF: p=0.003; CF: p=0.01; SF: p=0.018) and reported more financial difficulties (FI: p=0.015). In multivariate regression analysis, female sex, KPS at 1st follow-up < 70 and aggressive meningioma were independent factors of impaired HRQoL. This cross-sectional analysis demonstrates that HRQoL is impaired in aggressive meningioma patients who should be screened and treated for their psycho-oncological needs.

scholarly journals Epilepsy lifetime prevalence in Iran: a large population- based national survey

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hossein Pakdaman ◽  
Ali Amini Harandi ◽  
Koroush Gharagozli ◽  
Farshid Alaeddini ◽  
Akram Esfandani ◽  
...  
Keyword(s):  
Large Population ◽  
Life Time ◽  
Febrile Convulsion ◽  
Population Based ◽  
Cross Sectional Study ◽  
Survey Method ◽  
Two Phase ◽  
Related Factors ◽  
Cross Sectional ◽  
Health Related

AbstractEpilepsy has garnered increased public health focus because patients who suffer from epilepsy experience pronounced and persistent health and socioeconomic disparities despite treatment and care advances. The epidemiology of epilepsy is diverse in different countries and regions. This nationwide population-based cross-sectional study was conducted to determine the life time prevalence and health related factors of epilepsy for the first time in Iran through a two-phase door-to-door survey method. In phase I, a screening for epilepsy was performed on 68,035 people. Then in phase II, after the neurological evaluation of participants and reviewing medical records, 1130 subjects with epilepsy was confirmed. The life time prevalence of epilepsy was achieved to be 16.6 per 1000 people (95% CI 15.4–17.8) with the average age onset 19.1 ± 21.1 (active prevalence 9.5 per 1000 people). Focal seizure (59.3%), generalized epilepsy (38%) and unknown types of epilepsy (2.7%) were detected among participants. The overall life time prevalence of febrile convulsion was 4.1 per 1000 people. The frequency of attacks per year and per month were 3.0 ± 1.6 and 0.5 ± 0.1, respectively. Age-specific life time prevalence was highest among the age group of 15–19 years old [32.7 per 1000 persons (95% CI 29.1–36.8)] and it was higher in male (53.8%) than female (46.2%) participants. Our results showed that the life time prevalence of epilepsy in Iran is higher than worldwide average.

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