scholarly journals Contrasting SARS-CoV-2 epidemics in Singapore: Cohort studies in migrant workers and the general population

Author(s):  
Hannah E Clapham ◽  
Wan Ni Chia ◽  
Linda Wei Lin Tan ◽  
Vishakha Kumar ◽  
Jane M Lim ◽  
...  

Abstract From January 2020, Singapore implemented comprehensive measures to suppress SARS-CoV-2. Community transmission has been limited, although explosive outbreaks have occurred in migrant worker dormitories. We conducted longitudinal SARS-CoV-2 serology studies among 478 residents of a SARS-CoV-2 affected migrant worker dormitory between May and July 2020, and 937 community-dwelling adult Singapore residents with sera collected before September 2019 and in November/December 2020. By end 2020, <2 per 1000 (0.16%, 95% CrI: 0.008% - 0.72%) adult residents in the community were infected with SARS-CoV-2, approximately 4 times higher than the national notified case incidence. In contrast, in the migrant worker cohort, nearly two-thirds 63.8% (95% CrI: 57.9% - 70.3%) had been infected by July 2020; no symptoms were reported in >90% of these infections. SARS-CoV-2 suppression is feasible with rapid implementation of comprehensive control measures. However, the risk of large-scale epidemics in densely-populated environments requires specific consideration in preparedness planning.

2021 ◽  
Author(s):  
Ben Cooper ◽  
Stephanie Evans ◽  
Yalda Jafari ◽  
Thi Mui Pham ◽  
Cherry Lim ◽  
...  

Abstract Hospital-based transmission played a dominant role in MERS-CoV and SARS-CoV epidemics but large-scale studies of its role in the SARS-CoV-2 pandemic are lacking. Such transmission risks spreading the virus to the most vulnerable individuals and can have wider-scale impacts through hospital-community interactions. Using data from acute hospitals in England we quantify within-hospital transmission, evaluate likely pathways of spread and factors associated with heightened transmission risk, and explore the wider dynamical consequences. We show that hospital transmission is likely to have been a major contributor to the burden of COVID-19 in England. We estimate that between June 2020 and March 2021 between 95,000 and 167,000 patients acquired SARS-CoV-2 in hospitals with nosocomially-infected patients likely to have been the main sources of transmission to other patients. Increased transmission to patients was associated with hospitals having fewer single rooms and lower heated volume per bed. Moreover, we show that reducing hospital transmission could substantially enhance the efficiency of punctuated lockdown measures in suppressing community transmission. These findings reveal the previously unrecognised scale of hospital transmission, have direct implications for targeting of hospital control measures, and highlight the need to design hospitals better-equipped to limit the transmission of future high consequence pathogens.


Author(s):  
Hannah E. Clapham ◽  
Wan Ni Chia ◽  
Linda Wei Lin Tan ◽  
Vishakha Kumar ◽  
Jane M. Lim ◽  
...  

2017 ◽  
Vol 4 (1) ◽  
pp. 61
Author(s):  
Pradip Barde ◽  
Mohit Shahi ◽  
Nayana Pawar ◽  
Akshay Bhagat

Aim: To determine prevalence of Pre-hypertension in migrant worker population. Methods and Materials: An observational study were conducted on migrant workers from various types of working sites like construction, hotels and restaurants, industry in municipal limits of Nashik. Study Duration was six months with estimated sample size 1000. Body weight, height and blood pressure were recorded. Result: Of the 959 migrant workers (male and female) 809 (84.35%) belonged to 10-40 years age group, in which 22 % was female. We found that 30% of total population was overweight (BMI more than 25) and 63% workers are having abnormal blood pressure. The overall prevalence of hypertension in migrant population was 18.44%. 27% migrant populations were pre-hypertensive while 8% have Stage I Hypertension and 1% of total have Stage II hypertension. Conclusion: The prevalence of pre hypertension in migrant worker population was higher than prevalence in general population.


2021 ◽  
Author(s):  
Hannah E. Clapham ◽  
Wan Ni Chia ◽  
Linda WL Tan ◽  
Vishakha Kumar ◽  
Jane M. Lim ◽  
...  

2021 ◽  
Vol 17 (4) ◽  
pp. 431-441
Author(s):  
Stanislav Alkhasov ◽  
Sergey Ryazantsev

Amur Region (also named Amur Oblast) is a border region of Russia, characterized by socio-economic disadvantages (low standard of living, high prices) and unfavorable climatic conditions in part of the territory. Major projects in the field of construction, transportation, industrial production, fuel, and energy are being implemented in this region: the Vostochny Cosmodrome, the Amur Gas Processing Plant, etc. Territories of accelerated socioeconomic development (the Russian acronym is TOR) are being created. The regional government is making efforts to increase the investment attractiveness of the region, which is of interest to the business communities of neighboring countries. We formulate the portrait of a typical potential migrant worker who is ready to relocate to work in the Amur Region. According to the data of Internet recruitment, we show that the migration inflow prevails for the purpose of rotational basis (temporary) work. We identify the most significant donor regions, popular industries, and median salary expectations of potential migrant workers. We pay attention to the fact that the salaries of rotational basis workers are, on average, noticeably higher than the salaries of the local population: it becomes an additional factor of social tension. The incomes of rotational basis workers increase the values of regional average salaries, but in reality, this money does not remain inside Amur Region. Disproportions in the labour market are one more factor in the growth of inequality in the region, which additionally provokes the outflow of the local population from the region. Accordingly, the implementation of large-scale construction and fuel and energy projects in its current form is unable to overcome negative demographic trends, because it cannot individually solve the complex problems of socio-economic development of the Russian Amur river region. Social programs, such as «Zemsky Teacher» and «Zemsky Doctor», are not of a systematic nature. Ultimately, the social sector continues to degrade and does not receive a meaningful inflow of new highly qualified specialists (doctors, teachers, scientists, etc.) from outside.


2021 ◽  
Author(s):  
Young Ern Saw ◽  
Edina YQ Tan ◽  
P Buvanaswari ◽  
Kinjal Doshi ◽  
Jean CJ Liu

SummaryBackgroundIn the COVID-19 pandemic, international migrant workers have faced increased vulnerability on account of their status. This study examined the mental health burden of COVID-19 amongst low-waged migrant workers involved in large-scale dormitory outbreaks within Singapore.MethodsBetween 22 June to 11 October 2020, questionnaires were distributed in-person and online to 1011 migrant workers undergoing movement restrictions. Mental health symptoms were measured using the 21-item Depression, Anxiety and Stress Scale (DASS-21). As covariates, we assessed participants’ socio-demographics, quarantine status, COVID-19 health concerns, financial stability, and exposure to news and misinformation. Linear regression models were fitted to identify factors associated with each DASS-21 subscale.FindingsComplete movement restrictions were associated with increased depression and stress symptoms, while being diagnosed with COVID-19 was associated with increased anxiety. Participants who harboured fears about their health or job, perceived their health to be poorer, or had greater exposure to COVID-19 rumours reported higher depression, anxiety, and stress levels. Across the cohort, rates of severe or extremely severe depression (3.1%, 95% CI: 2.1-4.3%), anxiety (4.1%, 95% CI: 2.9-5.5%), and stress (1.3%, 95% CI: 0.7-2.2%) were similar to those observed in the general population for the host country (Singapore).InterpretationThe risk factors identified underscore how the ongoing pandemic may impact the mental health of migrant workers. At the same time, we observed resilience within the cohort, with no evidence of increased symptomology (relative to the general population).FundingJY Pillay Global Asia GrantResearch in ContextEvidence before this studyWe searched PubMed and Google Scholar for articles published in English between Jan 1, 2020 and Feb 20, 2021 using the following keywords: (“COVID*” OR “coronavirus”) AND (“mental*” OR “psychiatr*”) AND (“labo*r migra*” OR “migrant work” OR “foreign-work” OR “immigrant work” OR “economic migra*” OR “economic immigra*”). Focusing on international migrant workers employed in low-wage manual labour positions, we identified commentaries and interview-based studies describing the stressors faced by workers during the COVID-19 pandemic. However, we found no study documenting mental health symptoms within this group.Added value of this studyTo our knowledge, this is the first mental health survey of low-wage migrant workers during the COVID-19 pandemic. We observed that the mental health burden was highest amongst participants who encountered pandemic-related adversities (complete movement restrictions, testing positive for COVID-19), perceived the situation negatively (being fearful of their health or job, or judging their health to be poorer), or had higher exposure to COVID-19 rumours.Implications of the available evidenceOur findings provide a basis to identify and support at-risk migrant workers during the pandemic. Although we did not observe elevated rates of depression, anxiety, and stress symptoms within the migrant worker cohort, individual workers who experience poor mental health may find it harder to access health-care services (relative to the general population). Correspondingly, targeted support for at-risk migrant workers may serve to reduce mental health inequalities.


Author(s):  
A. Babirad

Cerebrovascular diseases are a problem of the world today, and according to the forecast, the problem of the near future arises. The main risk factors for the development of ischemic disorders of the cerebral circulation include oblique and aging, arterial hypertension, smoking, diabetes mellitus and heart disease. An effective strategy for the prevention of cerebrovascular events is based on the implementation of large-scale risk control measures, including the use of antiagregant and anticoagulant therapy, invasive interventions such as atheromectomy, angioplasty and stenting. In this connection, the efforts of neurologists, cardiologists, angiosurgery, endocrinologists and other specialists are the basis for achieving an acceptable clinical outcome. A review of the SF-36 method for assessing the quality of life in patients with the effects of transient ischemic stroke is presented. The assessment of quality of life is recognized in world medical practice and research, an indicator that is also used to assess the quality of the health system and in general sociological research.


Author(s):  
K. . Togawa

Agricultural workers can be exposed to a wide variety of agents (e.g. pesticides), some of which may have adverse health effects, such as cancer. To study the health effects of agricultural exposures, an international consortium of agricultural cohort studies, AGRICOH, was established. The present analysis compared cancer incidence between the AGRICOH cohorts and the general population and found lower overall cancer incidence in the AGRICOH cohorts, with some variation across cohorts for specific cancer types. The observed lower cancer incidence may be due to healthy worker bias or lower prevalence of risk factors in the agricultural populations. Further analysis is underway.


Author(s):  
Eliza R. Thompson ◽  
Faith S. Williams ◽  
Pat A. Giacin ◽  
Shay Drummond ◽  
Eric Brown ◽  
...  

Abstract Objective: To assess extent of a healthcare-associated outbreak of SARS-CoV-2 and evaluate effectiveness of infection control measures, including universal masking Design: Outbreak investigation including 4 large-scale point-prevalence surveys Setting: Integrated VA Health Care System with 2 facilities and 330 beds Participants: Index patient and 250 exposed patients and staff Methods: We identified exposed patients and staff and classified them as probable and confirmed cases based on symptoms and testing. We performed a field investigation and assessment of patient and staff interactions to develop probable transmission routes. Infection prevention interventions implemented included droplet and contact precautions, employee quarantine, and universal masking with medical and cloth facemasks. Four point-prevalence surveys of patient and staff subsets were conducted using real-time reverse-transcriptase polymerase chain reaction for SARS-CoV-2. Results: Among 250 potentially exposed patients and staff, 14 confirmed cases of Covid-19 were identified. Patient roommates and staff with prolonged patient contact were most likely to be infected. The last potential date of transmission from staff to patient was day 22, the day universal masking was implemented. Subsequent point-prevalence surveys in 126 patients and 234 staff identified 0 patient cases and 5 staff cases of Covid-19, without evidence of healthcare-associated transmission. Conclusions: Universal masking with medical facemasks was effective in preventing further spread of SARS-CoV-2 in our facility in conjunction with other traditional infection prevention measures.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Qing Cheng ◽  
Zeyi Liu ◽  
Guangquan Cheng ◽  
Jincai Huang

AbstractBeginning on December 31, 2019, the large-scale novel coronavirus disease 2019 (COVID-19) emerged in China. Tracking and analysing the heterogeneity and effectiveness of cities’ prevention and control of the COVID-19 epidemic is essential to design and adjust epidemic prevention and control measures. The number of newly confirmed cases in 25 of China’s most-affected cities for the COVID-19 epidemic from January 11 to February 10 was collected. The heterogeneity and effectiveness of these 25 cities’ prevention and control measures for COVID-19 were analysed by using an estimated time-varying reproduction number method and a serial correlation method. The results showed that the effective reproduction number (R) in 25 cities showed a downward trend overall, but there was a significant difference in the R change trends among cities, indicating that there was heterogeneity in the spread and control of COVID-19 in cities. Moreover, the COVID-19 control in 21 of 25 cities was effective, and the risk of infection decreased because their R had dropped below 1 by February 10, 2020. In contrast, the cities of Wuhan, Tianmen, Ezhou and Enshi still had difficulty effectively controlling the COVID-19 epidemic in a short period of time because their R was greater than 1.


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