scholarly journals Non hormonal management options for menstrual cycle irregularities

2019 ◽  
pp. 16-27 ◽  
Author(s):  
I. V. Kuznetsova

Menstrual rhythm disorders and symptoms associated with the menstrual cycle are one of the main reasons for women to make an appointment with a gynecologist. After the endocrinopathies and organic substrates of menstrual irregularities are excluded, the doctor is faced with the difficult task to treat conditions that reflect the functional dysfunction of the body and its adaptation to high stress load. It is beyond argument that hormone therapy is the main resource of a gynecologist, but it is not always acceptable and does not solve all the problems of normalizing psychoneuroendocrine status. The dependence of functional disorders on environmental stress factors allows a doctor to use lifestyle correction, including rational nutrition and adding various micronutrients, in a program to improve the quality of life, eliminate psychoemotional symptoms and symptoms of autonomic dysfunction. In turn, the restoration of the adaptive reserve of the body becomes key to the recovery of menstrual function.

2021 ◽  
Vol 1 (2) ◽  
pp. 11-18
Author(s):  
Yu. V. Petrova ◽  
◽  
V. A. Popova ◽  
T. O. Azarnova ◽  
S. V. Pozyabin ◽  
...  

Turkey breeding is one of the most stress loaded areas of poultry farming. In order to remedy negative conditions caused by the stress factors associated with artificial incubation, the team of authors suggests transovarian use of a promising and all-pervasive antioxidant in the body – Glutathione. The article presents evidence of the presence of such properties in the claimed tripeptide, which was expressed in a decrease in the products of the peroxide cascade and an increase in the antioxidant activity of blood serum. It is proved that their implementation determines conditions to obtain biologically adequate offspring, promotes an implementation of their productive qualities in further ontogenesis. According to the results of the meat Biosafety study, it is recognized that glutathione does not negatively affect the quality and safety of meat.


2020 ◽  
Vol 22 (3) ◽  
pp. 68-71
Author(s):  
A. M. Schegol’kov ◽  
A. A. Blaginin ◽  
A. Ya. Fisun ◽  
D. V. Cherkashin ◽  
R. G. Makiev ◽  
...  

Abstract. Factors of disadaptation of pilots after combat stress are analyzed as one of the main factors in the development of post-traumatic stress disorder. It was found that the effects of combat stress have a great impact on young, thin pilots, with a predominance of the parasympathetic division of the autonomic nervous system and a reduced basic metabolism of the body. The data obtained allow for early diagnosis and identification of functional disorders in pilots for their medical and psychological rehabilitation. The use of the proposed discriminant function can be divided into adapted and unadapted (differently processing traumatic experience), for the development of appropriate rehabilitation programs within their medical and psychological rehabilitation. The revealed decrease in the reserve capabilities of the Central nervous system and the adaptive capabilities of the body of pilots subsequently leads to a decrease in the reliability of the professional activity of the pilot with an increase in its physiological price. In terms of methodology, understanding the postponement of the negative impact of combat stress factors on the pilots body requires constant measures for early detection and correction of emerging functional disorders. The consequences of combat stress are considered as an integral reaction of the body to the complex impact of various factors of combat stress, which is manifested at the psychophysiological and somatic levels and leads to early disqualification of pilots for medical reasons.


Author(s):  
Serbenuyk A. V. ◽  
Kaminskiy V. V.

The article presents an analysis of literature data and the results of our own retrospective studies of the characteristics of the menstrual cycle in female combatants who have undergone concussion. Clinical and anamnestic factors have been identified that negatively affect the menstrual function of women of reproductive age, who received contusions during hostilities. The relationship between the state of mental health of women and menstrual irregularities has been established. Aim: to identify and evaluate changes in the menstrual function of women - veterans of reproductive age. Also, to establish the relationship between menstrual irregularities in women - veterans of reproductive age who have undergone contusion, and the state of their somatic and mental health.Materials and method: The research was conducted at the Department of Obstetrics, Gynecology and Reproductology of the National University of Health of Ukraine named after P.L. Shupika. To achieve this goal, a comprehensive clinical and laboratory examination was performed in 567 women of reproductive age (main group and comparison group) who participated in hostilities and suffered contusions, the average age of the subjects was 27.08 ± 4.23 years.The period of stay in the combat zone is 29.34 ± 9.21 months, the time from the moment of receiving a mild traumatic brain injury (contusion) is 18.8 ± 9.2 months. Group I - 399 fertile women who suffered contusions during the fighting with PKS. Group II - 168 women of childbearing age who suffered contusions during hostilities without PKS (mean age 32.21 ± 7.32 years).Results: The results of the studies revealed statistically significant deviations in the characteristics of the menstrual cycle of women who participated in hostilities who were injured with PKS, compared with women without PKS. It has been proven that women-viskovosluzhvits more often develop menstrual irregularities, namely a decrease or increase in the number, lengthening or shortening of the menstrual cycle by 7 days. Taking into account the revealed menstrual irregularities in the women under study, it can be argued that the detected changes are due to the influence of both craniocerebral trauma and stress factors associated with military service. This justifies the need to develop a program for monitoring and supporting the reproductive health of women-viyskovoservices, as well as medical and psychological rehabilitation of veterans, aimed at their full adaptation to a peaceful life.


2020 ◽  
Vol 5 (3) ◽  
pp. 39-45 ◽  
Author(s):  
Nina Chupsheva ◽  
Sergey Karamaev ◽  
Anna Karamayeva

The research goal is to increase the duration of the period of productive use of cows in modern complexes for milk production. The object of research is cows of the newly created intra-breed middle Volga type of black-and-white breed, culled for various reasons from the herd in the period from 2016 to 2018. All animals for further statistical processing of the studied indicators were divided into four groups, taking into account the type of stress resistance according to the method of E. p. Kokorina in the modification described by E. N. Letyagina. It was found that all hematological indicators decrease with increasing stress resistance in cows, except for the content of white blood cells. An increase in the concentration of white blood cells in the blood by 6.8-41.9% is probably a protective reaction of the body. Different reactivity of cows to the action of stress factors has an impact on the natural resistance of their body. A decrease in BASC by 3.2-10.5% was found, LASC – by 3.5-9.0%, FUNK-by 1.8-7.3%. When stress resistance decreases, the concentration of immunoglobulins in the blood decreases: IgG-by 3.9 – 11.2%, IgM-by 1.1 – 22.5%, IgA-by 3.4 – 24.1%. Studies have shown that cows of the first type of stress was superior to their peers with high stress-STU life expectancy at 262,6-1264,8 day (11,6-100%; P<0,05-0,001); in the long-STI period of productive use – on 0,2-2,5 lactation (4,7-125%; P<0.001); the magnitude of the average milk yield per lactation on 487-2175 kg of milk (8,5-53.6 percent; P<0,05-0,001); the value of lifetime milk yield – for 3340-19924 kg of milk (13.5-245.5%; P<0.01-0.001); for milk yield per 1 day of life-0.2-4.7 kg (1,8-73,4%; P<0,001), on the 1st day of lactation – 2,3-5,5 kg (13,9-41,4%; P<0,001). It is recommended that the" breeding core " of the herd be equipped with animals of types I and II of stress resistance. When using type II stress resistance cows, additional attention should be paid to the milk productivity of their mothers when selecting breeding bulls.


Author(s):  
Bárbara Pessali-Marques

The physiological alterations due to the variation in female hormones' concentrations, oestrogen and progesterone, will allow pregnancy or the period to occur. However, this hormone fluctuation across the menstrual cycle phases may affect way more than only the ability to get pregnant. Although the female hormones' primary action is related to the ovum's maturation and implantation, their variation causes many physiological and emotional secondary effects. It is expected that this interaction may, in turn, influence exercise performance, including dance performance; therefore, it is essential to understand better what happens in the body during the menstrual cycle. This understanding may allow better awareness and control of the symptoms, bringing a better quality of life and more remarkable dance performance.


Introduction. One of the common chronic dermatoses that have a direct impact on the quality of life of patients is acne. The occurrence of psycho-emotional disorders due to the location of elements in the open areas of the body. Given the high prevalence of acne in puberty (up to 85 % of adolescents have episodes of acne of varying severity), there is a need to find new algorithms for acne treatment to prevent the progression of social maladaptation and depressive states. Materials and methods. The study included 140 patients who were divided into 3 groups depending on the presence of comorbid pathology and treatment methods: group 1 — patients with acne who were underwent standard treatment for 60 days, group 2 — patients with acne in comorbidity with demodecosis, group 3 — patients with acne in comorbidity with demodecosis and functional disorders of the digestive system, who were additionally treated with a laser therapy. Treatment efficacy was evaluated using the GAGS scale and the DLQI questionnaire on days 14, 28 and 60 of therapy. Results. Evaluation of the results on day 60 shows a decrease in the manifestations of inflammation by 50 % in groups 2 and 3, and by 29 % in the standard therapy group. Improving of the quality of life in groups 2 and 3 was by 70 %, while in the group 1 — by 35 %. The following correlations were established: r = + 0.9 — between the severity of VC manifestations and the presence of comorbid pathology, r = + 0.71 — between the severity of VC and the assessment of quality of life, r = + 0.69 — between the presence of acne comorbidity with demodecosis and FDGBS and the effect on quality of life (p < 0.005). Conclusions. Optimization of the treatment algorithm for acne patients in comorbidity with demodecosis and functional disorders of the hepatobiliary system is achieved by the use of combined treatment using laser therapy, which significantly improves the quality of life of patients.


2019 ◽  
Vol 96 (5) ◽  
pp. 414-417
Author(s):  
Yu. D. Gubernskiy ◽  
V. N. Fedoseeva ◽  
A. K. Makovetskaya ◽  
N. V. Kalinina ◽  
T. G. Fedoskova

There are considered ecological-hygienic aspects of the sensitization rate of population in residential environmental. The considerable part of the life of a person passes in conditions of residential environmental, he is exposed to the whole complex of sensitizing factors, with the house dust being the most important among these factors. Results. According to results of our research, the greatest number of allergic reactions was noted under the contact with domestic, pollen and epidermal allergens. In the structure of allergic diseases in the population the most frequent were allergic rhinitis and allergic rhinoconjunctivitis. The overwhelming majority of observed cases was shown to suffer from functional disorders of the autonomic nervous system, gastrointestinal tract, and there was also observed the presence of chronic foci of inflammation. As a result of the executed comprehensive hygienic evaluation of the quality of residential environment there was established that in conditions of residential and public buildings the array of chemicals also had allergical effect on population. Discussion. The complex chemical pollutants of the residential environment in isolation was shown to fail to exert anaphylactogenic activity, whereas in complex with house dust allergen there are revealed the decline in immunological indices of the nonspecific resistance and inhibition of functional activity of T-suppressors, and amplification of immediate hypersensitivity in condition of impact of allergical complex of domestic dust. The existence of disorders of different functional systems of organism also provokes the development of the state of the hypersensitivity of population. Conclusions. The sensitization of the population was shown to be directly affected by the combined effect on human sensitization with allergenic components of house dust and chemical pollutants. Factors contributing to the development and occurrence of allergic pathologies among the population include: the level of chemical contamination of residential environment, various functional disorders of the body systems, which give rise in increased sensitization of the population.


2019 ◽  
Vol 9 (2) ◽  
pp. 239-245
Author(s):  
N. V. Bogolyubov ◽  
M. G. Chabaev ◽  
Yu. P Fomichev ◽  
E. Yu. Tsis ◽  
A. A. Semenova ◽  
...  

Modern intensive technologies for handling and growing highly productive animals are accompanied by significant changes in their homeostasis causing stress and adversely affecting their health and the quality of the products obtained from them. Depending on the cause, stress is classified as social (technological), environmental, dietary, and immunological. Various types of stress adversely affect the body and contribute to endocrine, energy balance, and carbohydrate-lipid metabolism disturbances, which adversely affects the animal resistance to diseases, productivity and reproductive characteristics. Stress leads to metabolic disorders and changes in the ratio of muscle and fatty tissues. Every year, the manifestations of antemortem and postmortem pathological changes in the microstructure of animal muscle tissue are increasingly noted. Moreover, the affected structures of muscle fibers are characterized by hyper contraction, disruption of cell membranes, and formation of extracellular protein substance represented by denatured forms of proteins reducing the nutritional value and consumer characteristics of the final product. The use of antioxidants in pig diets, including natural ones, helps to reduce the impact of environmental stress factors on animals and increase their adaptive capacity. This review focuses on the ways to reduce stress and the effect of flavonoids, including quercetin, whose properties have been extensively studied in recent years, in order to increase the resistance of highly productive animals to various stress factors.


2007 ◽  
Author(s):  
Winslow G. Gerrish ◽  
M. Kathleen B. Lustyk ◽  
Nate Reiss ◽  
Karen C. Olson

2007 ◽  
Author(s):  
Winslow G. Gerrish ◽  
Andrea C. Miller ◽  
M. Kathleen B. Lustyk ◽  
Karen C. Olson

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