scholarly journals Variation of intraocular pressure comparing rebound (TONOVET Plus®) and applanation (TONO-PEN VET®) tonometry in New Zealand rabbits treated with Amlodipine®

2021 ◽  
Vol 16 (3) ◽  
pp. 10-27
Author(s):  
Javier Dario Murillo Arroyave ◽  
Sara M Robledo ◽  
Jaime Montaño ◽  
Sandra Patricia Acevedo
Keyword(s):  
Blood Pressure ◽  
Intraocular Pressure ◽  
New Zealand ◽  
Diastolic Pressure ◽  
Systolic Pressure ◽  
Systemic Blood Pressure ◽  
Applanation Tonometry ◽  
Control Group ◽  
New Zealand White Rabbits ◽  
New Zealand Rabbits

Rabbits have played an important role in ophthalmological research processes, however in the environment there has been a deficiency of sensitive equipment in measurement of intraocular pressure for this species. To compare intraocular pressure (IOP) measured with rebound (TONOVET Plus®) and applanation (TONO-PEN VET®) tonometry in healthy New Zealand rabbits treated with Amlodipine. Twelve healthy male New Zealand white rabbits, 5 months old; two groups with 6 individuals were used in this study. The experimental group was given Amlodipine® at a dose of 5 mg/kg, once a day for a month. Blood pressure and intraocular pressure were measurement before treatment and 6 h after treatment in a period of one month. A trend is noted where the group of animals treated with amlodipine® presents lower values than the control group, both in systolic and diastolic pressure. The systolic pressure of the control group showed an average of 116.5 ± 7.9 mmHg and 117.4 ± 8.9 mmHg and the treatment group showed an average of 113.6 ± 7.9 mmHg and 111.8 ± 10.0 mmHg (pretreatment and posttreatment respectively). Tonometry: the values obtained using the TONOVET Plus® (19 ± 3 mmHg) are on average higher than the values obtained using the TONO-PEN VET® (17 ± 3 mmHg). It was possible to demonstrate the relationship between systemic blood pressure and intraocular pressure in New Zealand white rabbits. Rebound tonometry showed less variability in results than applanation tonometry. This study confirmed that both tonometers are reliable for measuring IOP in rabbits.

Grape juice and aerobic exercise on blood pressure

2019 ◽  
Vol 50 (5) ◽  
pp. 987-998 ◽  
Author(s):  
Juliane Barroso Leal ◽  
Juçara Barroso Leal ◽  
Joaline Barroso Portela Leal ◽  
Yan de Lima Borges ◽  
Maria Ivone Leal de Moura ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Physical Exercise ◽  
Aerobic Exercise ◽  
Diastolic Pressure ◽  
Systolic Pressure ◽  
Grape Juice ◽  
Exercise Group ◽  
Control Group ◽  
Content Type ◽  
Before And After

Purpose This paper aims to verify the effect of 12 weeks of grape juice (GJ) consumption associated with aerobic exercise on the variation of the hypertensive elderly pressure. Design/methodology/approach A total of 45 hypertensive elderly of both sexes were distributed into: control group (CG, n = 10), exercise group (EG, n = 10), juice group (JG, n = 12) and juice and exercise group (JEG, n = 13). Blood pressure and heart rate were checked weekly before exercise in JG and JEG, and before and after intervention in all groups, with JG and JEG supplemented with 200 mL of GJ. Three weekly sessions of moderate walking were applied. Findings There was a reduction in EG, JG and JEG for systolic pressure and diastolic only for JG and JEG. The GJ consumption to the practice of aerobic exercise provided reductions in the arterial pressure of hypertensive, in addition to stabilization of the diastolic pressure. Research limitations/implications Although the objective of the study was to compare the effect and value of intervention with controls, the study had no intervention in food consumption, which could have led to more significant results. There was a limitation in the control drink, leading the study not to be blind, which may have impaired the results. However, it is probably not a bias, as the groups were divided by residence area, and therefore, had no direct contact with the other groups. Another limitation was that the sample size was still small, which would lead to more reliable results. Finally, although the existing limitations cannot be disregarded, the results of this research are very promising, especially when the objective is the effect of GJ and aerobic exercise on blood pressure, with the possibility of implementing supplemental GJ and the inclusion or not of exercise to the hypertensive elderly. Originality/value The paper deals with the benefits of GJ consumption associated with aerobic physical exercise on the blood pressure of elderly hypertensive patients. Considering that GJ along with physical exercise was enough to reduce the blood pressure of hypertensive elderly, this may be a new model to be used to reduce and/or control blood pressure, and GJ and the exercise to be part of the daily life of the population.

scholarly journals Diet Health Education Effect on Elderly Behavior with Hypertension

2018 ◽  
Vol 6 (6) ◽  
Author(s):  
Suratun Haryono ◽  
Paula Krisanty ◽  
Santa Manurung
Keyword(s):  
Blood Pressure ◽  
Health Education ◽  
Service Providers ◽  
Diastolic Pressure ◽  
Systolic Pressure ◽  
Sampling Technique ◽  
Patient Characteristics ◽  
Bivariate Analysis ◽  
Control Group ◽  
Hypertensive Patients

Hypertension is defined as a persistent blood pressure where the systolic pressure is above 140mmHg and the diastolic pressure is above 90 mmHg. Empowering patients by providing ongoing care services can create ongoing communication, building relationships between clients and service providers so that they will increase patients' confidence in overcoming problems. The visit of hypertensive patients has increased every month, health education about hypertension diet is generally carried out when the patient is diagnosed with hypertension and does not regularly monitor the implementation of the diet. The purpose of this study was to determine the difference in the effect of the approach to sustainable nursing services through health education about diet to changes in blood pressure of hypertensive patients. The research method uses a quasi-experimental design pre-post test with the control group. The study population was 108 respondents, the sampling technique used purposive sampling and obtained a sample of 33 respondents for each intervention and control group. Patient characteristics data were taken using a questionnaire, while blood pressure data was carried out by blood pressure examination. Data analysis used univariate, bivariate analysis with paired t-test statistical test. The results showed that there was a significant influence on diet health education on changes in elderly behaviour.  

THE BRACHIAL TO DIGITAL BLOOD PRESSURE GRADIENT IN NORMAL SUBJECTS AND IN PATIENTS WITH HIGH BLOOD PRESSURE

1958 ◽  
Vol 36 (9) ◽  
pp. 889-893 ◽  
Author(s):  
P. Gaskell ◽  
A. M. Krisman
Keyword(s):  
Blood Pressure ◽  
Pressure Gradient ◽  
Diastolic Pressure ◽  
Systolic Pressure ◽  
Normal Subjects ◽  
Normal Blood ◽  
Control Group ◽  
Normal Blood Pressure ◽  
Hypertensive Patients ◽  
Systolic Pressure Gradient

The brachial and digital blood pressures were estimated by auscultatory techniques in 10 patients with essential hypertension and in a group of 6 subjects with normal blood pressure who were in a state of regulated peripheral vasoconstriction and again when they were in a state of regulated vasodilatation. The brachial to digital systolic and diastolic pressure gradients in both control subjects and hypertensive patients were greater when the individuals were heated than when they were cooled. The brachial to digital diastolic pressure gradient in the hypertensive patients was not significantly different from that in the subjects with normal blood pressure. However, the systolic pressure gradient was greater in the hypertensive patients than in the control group both when the individuals were heated and when they were cooled.

Effects of low-dose ketanserin on atherosclerosis in rats and rabbits

2010 ◽  
Vol 88 (11) ◽  
pp. 1054-1060 ◽  
Author(s):  
Yong-Sheng Yu ◽  
He-Hui Xie ◽  
Ling Li ◽  
Shu-Wei Song ◽  
Ping Han ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Vitamin D ◽  
New Zealand ◽  
Treatment Group ◽  
Low Dose ◽  
Control Group ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
New Zealand White Rabbits

The present study was designed to test the hypothesis that a small dose of ketanserin, which enhances baroreflex activity, prevents the early lesions of atherosclerosis. In experiment 1, baroreflex sensitivity (BRS) was measured in 31 spontaneously hypertensive rats (SHRs) in a conscious state using a computerized blood pressure monitoring system. Four weeks later, the rats were administered vitamin D3 and fed a high-cholesterol diet for 8 weeks to induce atherosclerosis. Then their hearts and aortae were removed for pathological examination. A negative correlation was found between BRS and the scores of coronary (r = –0.460, P < 0.01) and aortic atherosclerosis (r = –0.448, P < 0.05) in SHR. In experiment 2, SHRs were divided into 3 groups (n = 10 in each group) and received a dose of ketanserin of 0.3, 1.0, and 3.0 mg/kg (i.g.), respectively. At the smallest dose (0.3 mg/kg), ketanserin did not lower blood pressure but enhanced BRS. In experiment 3, SHRs were administered vitamin D3, fed a high-cholesterol diet, and simultaneously treated with low-dose ketanserin. The atherosclerosis scores of the treatment group were significantly lower than those of the control group (coronary score: 0.90 ± 0.14 vs. 1.76 ± 0.27, P < 0.05; aortic scores: 1.00 ± 0.39 vs. 2.18 ± 0.41, P < 0.05). In experiment 4, male New Zealand White rabbits were fed a high-cholesterol diet and treated with low-dose ketanserin at the same time. The atherosclerosis scores of the treatment group were significantly lower than those of the control group (aortic scores: 0.26 ± 0.20 vs. 0.60 ± 0.31, P < 0.05). In conclusion, the present study demonstrated, for the first time, that low-dose ketanserin prevented the development of atherosclerosis independent of its blood pressure lowering action in SHRs and New Zealand White rabbits at least in part via enhancement of arterial baroreflex function.

scholarly journals Blood Pressure and Heart Rate Alterations through Music in Patients Undergoing Cataract Surgery in Greece

2015 ◽  
Vol 7 ◽  
pp. OED.S20960 ◽  
Author(s):  
Kyriakoula Merakou ◽  
Georgia Varouxi ◽  
Anastasia Barbouni ◽  
Eleni Antoniadou ◽  
Georgios Karageorgos ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Systolic Blood Pressure ◽  
Cataract Surgery ◽  
Coping Skills ◽  
Diastolic Pressure ◽  
Intervention Group ◽  
Systolic Pressure ◽  
Control Group ◽  
Stress Coping

Introduction Music has been proposed as a safe, inexpensive, nonpharmacological antistress intervention. The purpose of this study was to determine whether patients undergoing cataract surgery while listening to meditation music experience lower levels of blood pressure and heart rate. Methods Two hundred individuals undergoing cataract surgery participated in the study. Hundred individuals listened to meditation music, through headphones, before and during the operation (intervention group) and 100 individuals received standard care (control group). Patients stress coping skills were measured by the Sense of Coherence Scale (SOC Scale). Systolic and diastolic blood pressure and heart rate were defined as outcome measures. Results According to the SOC Scale, both groups had similar stress coping skills (mean score: 127.6 for the intervention group and 127.3 for the control group). Before entering the operating room (OR) as well as during surgery the rise in systolic and diastolic pressures was significantly lower in the intervention group ( P < 0.001). Among patients receiving antihypertensive therapy, those in the intervention group presented a lower increase only in systolic pressure ( P < 0.001) at both time recordings. For those patients in the intervention group who did not receive antihypertensive treatment, lower systolic blood pressure at both time recordings was recorded ( P < 0.001) while lower diastolic pressure was observed only during entry to the OR ( P = 0.021). Heart rate was not altered between the two groups in any of the recordings. Conclusions Meditation music influenced patients' preoperative stress with regard to systolic blood pressure. This kind of music can be used as an alternative or complementary method for blood pressure stabilizing in patients undergoing cataract surgery.

scholarly journals PENGARUH MASSAGE AROMATHERAPHY LAVENDER TERHADAP PERUBAHAN TEKANAN DARAH PADA IBU HAMIL DENGAN PREEKLAMPSIA DI PBM. LILIS SURYAWATI DESA SAMBONG DUKUH KECAMATAN JOMBANG KABUPATEN JOMBANG

2019 ◽  
Vol 5 (2) ◽  
pp. 27-34
Author(s):  
Any Isro'aini
Keyword(s):  
Blood Pressure ◽  
Pregnant Women ◽  
Diastolic Pressure ◽  
Blood Pressure Reduction ◽  
Systolic Pressure ◽  
Pharmacological Therapy ◽  
Control Group ◽  
P Value ◽  
Significant Difference ◽  
Experimental Group

Hypertension in preeclampsia is found in pregnant women with gestational age> 20 weeks. Hypertension is defined where systolic pressure above 140 mmHg and diastolic pressure above 90 mmHg. Handling hypertension in pregnant women up to now is still using pharmacological therapy or drugs by 100%. One nonpharmacological therapy that can lower blood pressure is aromatherapy lavender massage therapy. The purpose of this study was to determine the effect of lavender aromatherapy massage on blood pressure reduction in pregnant women with preeclampsia.The design of this study used the Quasy Experiment Design with the Control Time Series Design research design, where the study used two groups divided into experimental groups and control groups. In this study both groups were pre-tested and after being given treatment in the experimental group a post-test was carried out in both groups. The research sample amounted to 50 respondents, of which 25 respondents became the experimental group and 25 became the control group. This research took place at PBM. Lilis Suryawati, Sambong village, Dukuh, Jombang District, Jombang Regency. This research was conducted from February to April 201.                    The results showed a significant difference between the blood pressure of the experimental group who were treated and the control group that was not treated. The systolic blood pressure of both groups p-value 0.003 and the value of Z -4.007. While diastolic blood pressure in both groups p-value 0,000 and Z value -5,559.                    It is expected that the midwifery profession can provide information about the importance of aromatherapy lavender massage to reduce blood pressure in pregnant women with preeclampsia, so that it can minimize the occurrence of complications in pregnant women with preeclampsia.

scholarly journals EFEKTIFITAS AIR KELAPA HIJAU MUDA TERHADAP PENURUNAN TEKANAN DARAH TINGGI PADA LANSIA DI POSYANDU USILA PUSKESMAS PERAK TIMUR SURABAYA

2018 ◽  
Vol 11 (1) ◽  
Author(s):  
Ninik Ambar Sari ◽  
Dya Sustrami
Keyword(s):  
Blood Pressure ◽  
Treatment Group ◽  
High Blood Pressure ◽  
Diastolic Pressure ◽  
Systolic Pressure ◽  
T Test ◽  
The Body ◽  
Coconut Water ◽  
Control Group ◽  
Lower Systolic Blood Pressure

Hypertension is an increase in blood pressure where the systolic pressure is more than 140 mmHg and diastolic pressure is more than 90 mmHg. The cause of the onset of hypertension can be of age factor. Elderly who suffer from hypertension usually cause interruption of daily activities, so routine treatment is needed in order not to cause complications. Young coconut water contains potassium, magnesium and vitamin C which has benefits to help the body regulate blood pressure, so it can reduce hypertension. The purpose of this study was to determine the effect of young coconut water on the decrease of high blood pressure in the elderly. Experimental Quasy research design with Non-Equivalent Control Group Desaign approach. The population of this study is elderly who are not dependence of hypertension drugs as much as 32 people with the number of samples of 30 respondents selected by Probability Sampling with Simple Random Sampling approach. The independent variable is young coconut water therapy, the dependent variable is the decrease of high blood pressure. Data were collected using questionnaires and observations. Data were analyzed by using Paired t-test and Independent t-test. The results showed that the consumption of young coconut water as much as 250 ml morning and afternoon for 2 weeks in the treatment group can lower systolic blood pressure. The independent t test in the treatment group and the control group obtained the result p = 0.013 (p <a = 0.05). The implication of this study is that young coconut water can lower blood pressure in elderly people with hypertension, so that young coconut water treatment can be used as one of the non-pharmacological alternative to reduce blood pressure.  

Abstract 12973: Atrial Fibrillation is Associated With Increased Central Blood Pressure and Arterial Stiffness

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Priit Pauklin ◽  
Jaan Eha ◽  
Kaspar Tootsi ◽  
Rein Kolk ◽  
Rain Paju ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Blood Pressure ◽  
Arterial Stiffness ◽  
Pulse Pressure ◽  
Augmentation Index ◽  
Systolic Pressure ◽  
Applanation Tonometry ◽  
Central Blood Pressure ◽  
Control Group ◽  
Lack Of Information

Background: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in clinical practice, yet there is a lack of information about the hemodynamic profile and arterial stiffness of these patients. Purpose: The purpose of this study is to describe the differences in arterial stiffness and central blood pressures in patients with paroxysmal/persistent AF compared to a healthy control group. Methods: We included 76 patients with paroxysmal and persistent AF who underwent electrical cardioversion or pulmonary vein isolation (PVI) for AF. Carotid-femoral pulse wave velocity (cfPWV), augmentation index (AIx) and central blood pressure (cBP) were measured by applanation tonometry. All measurements were done in sinus rhythm (SR). We compared the results with 75 healthy age matched individuals. Results: Patients with a history of AF had higher cfPWV compared to the control group (8,0 m/s vs 7,2 m/s, p<0,001). AF patients also had higher central systolic blood pressure (cSBP) (118 mmHg vs 114 mmHg, p=0,03) and central pulse pressure (cPP) (39 mmHg vs 37 mmHg, p=0,03), without differences in peripheral systolic pressure (pSBP) (127 mmHg vs 123 mmHg, p=0,13), peripheral diastolic blood pressure (pDPB) (78 mmHg vs 76 mmHg, p=0,14) and peripheral pulse pressure (pPP) (48 mmHg vs 47 mmHg, p=0,37). There was no difference in heart rate (HR) (58 vs 61 bpm, p=0,08) (Table 1). In a multiple regression analysis (adjusted R 2 = 0,37) where cfPWV was set as the dependent variable and adjusting for age, sex, HR, weight, mean central arterial pressure (cMAP), estimated glomerular filtration rate (eGFR), the AF group remained to be an independent predictor for cfPWV (p=0,016). Conclusions: Patients with atrial fibrillation have a higher cSBP, cPP and cfPWV compared to healthy subjects without differences in peripheral blood pressure and HR. These findings support the hypothesis that arterial stiffness may play an important role in the development of atrial fibrillation.

scholarly journals Inter-relationship between ageing, body mass index, diabetes, systemic blood pressure and intraocular pressure in Asians: 6-year longitudinal study

2018 ◽  
Vol 103 (2) ◽  
pp. 196-202 ◽  
Author(s):  
Jacqueline Chua ◽  
Miao Li Chee ◽  
Calvin Woon Loong Chin ◽  
Yih Chung Tham ◽  
Nicholas Tan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Body Mass Index ◽  
Intraocular Pressure ◽  
Body Mass ◽  
Reference Group ◽  
Systemic Blood Pressure ◽  
Applanation Tonometry ◽  
Linear Regression Models

BackgroundTo investigate the biological effect of ageing on intraocular pressure (IOP) and risk factors in a population-based cohort study of Malay and Indian adults.MethodsParticipants aged 40–80 years were recruited for baseline and 6-year follow-up visits between 2004–2009 and 2010–2015, respectively. Blood pressure (BP) was measured with an automatic BP monitor and IOP were obtained by Goldmann applanation tonometry. Main outcome was change in IOP, defined as the difference between the 6-year IOP and the baseline IOP. Linear regression models were used to investigate the association of changes in IOP with risk factors.Results  Participants without a history of glaucoma or cataract surgery at baseline were included (n = 3188; mean age: 54±9 years) . Their average IOP was reduced (−0.5±3.1 mm Hg), except for those who developed hypertension at follow-up (0.0±3.1 mm Hg). After adjusting for covariates, changes in IOP were negatively associated with age (β=−0.07, 95% CI −0.13 to −0.01) and positively associated with body mass index, diabetes, hypertension (normotensive as reference group; newly developed hypertensive (β=0.67, 95% CI 0.39 to 0.95) and chronic hypertensive (β=0.46, 95% CI 0.22 to 0.70)), baseline systolic BP (SBP) (β=0.20, 95% CI 0.14 to 0.26) and diastolic BP (DBP) (β=0.33, 95% CI 0.22 to 0.44), as well as with 6-year increases in SBP (β=0.27, 95% CI 0.21 to 0.33) and DBP (β=0.52, 95% CI 0.41 to 0.63).ConclusionsNormal ageing and reduced systemic BP are associated with reduced IOP in Malay and Indian adults. Given that high IOP is a risk factor for glaucoma, our finding highlights the importance of controlling hypertension in older adults, where hypertension and glaucoma incidences are on a rise.

Central Blood Pressure and Heart Output in Surfaced and Submerged Frogs

1965 ◽  
Vol 42 (2) ◽  
pp. 339-357
Author(s):  
G. SHELTON ◽  
D. R. JONES
Keyword(s):  
Blood Pressure ◽  
Rana Pipiens ◽  
Pulse Wave ◽  
Diastolic Pressure ◽  
Peripheral Resistance ◽  
Systolic Pressure ◽  
Systemic Blood Pressure ◽  
Minute Volume ◽  
Central Blood Pressure ◽  
Systemic Blood

1. The systemic blood pressure of Rana pipiens and R. temporaria is slightly higher than the pulmocutaneous pressure at systole and much higher at diastole. The pulses differ in shape and a conus component can be seen in the systemic wave. 2. Submersion of the animal causes a fall in systolic pressure in both arches, the diastolic pressure remaining relatively constant. The shape of the pulse wave changes, the conus component being accentuated and visible in recordings from both arches. 3. Heart rate and stroke volume fall during submersion so that after 30 min. under water the minute volume may be 20-50% of the value at the surface. The heart becomes increasingly full of blood. 4. The differences in systemic and pulmocutaneous pressures are explained in terms of resistance, compliance and flow in lung and body circuits. The same general relationships persist during submersion but selective increases in peripheral resistance must occur to maintain the central blood pressure in face of falling heart output.

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