scholarly journals Morphological characteristics of uterine tubes ampullae in elderly females

Author(s):  
Irina A. Balandina ◽  
Anna M. Nekrasova

The aim of the study is to determine the size and to identify the features of histoarchitectonics of the uterine tube ampulla of an old-aged female. Materials and methods. The ampulla of both uterine tubes was examined in 26 nulliparous and 78 giving birth elderly women using morphometric, histological, immunohistochemical, and micrometric research methods. Results. The length and outer diameter of uterine tubes at the points of transition of isthmus into the ampulla and ampulla into the infundibulum as well as in the central part of ampulla are characterized by the absence of a statistically significant difference in parameters in nulliparous and giving birth women. The histoarchitectonic features of the ampullae of the uterine tubes in nulliparous and giving birth women in old age consist in the flattening of the epithelium of the mucous membrane, which forms many closely spaced thickened folds that create an uneven narrowing of the ampulla lumen, and the proliferation of connective tissue between the bundles of muscle fibers of the muscular membrane. The presence of Ki-67 expression in single cells of less than 1%, as well as a thin layer of epithelial membrane antigen in the epithelium of the ampulla along with the complete absence of its expression in the stroma reflect normal tissue regeneration and act as an equivalent to the anatomical norm in elderly females. When comparing lumen areas of ampulla and its wall at mid-section as well as the circumference of epithelial lining, a predominance of parameters in the right uterine tube was revealed (p<0.01). Conclusion. The study showed the similar qualitative and quantitative morphological characteristics of the uterine tube ampullae both in nulliparous and giving birth females in old age.

2021 ◽  
Vol 28 (4) ◽  
pp. 68-72
Author(s):  
Anatoly A. Balandin ◽  
Lev M. Zheleznov ◽  
Irina A. Balandina ◽  
Valery S. Shelud'ko

Investigation which devoted to the study of the age characteristics of the human body are becoming increasingly important. Magnetic resonance tomography is the most informative diagnostic method for intravital visualization of tissues and structures of the brain. It also allows you to more accurately see the picture of morphological features with age-associated changes. The aim of the study was to carry out a comparative analysis of the age-related morphometric characteristics of the cerebellum in male with mesocranic type of cranium in young and old age according to the data of magnetic resonance tomography. The analysis of the results of a morphometric study of the cerebellum on tomograms of 91 men examined for medical reasons was carried out. Depending on the age, the subjects were divided into two groups. Group I included 52 young men (22–27 years old, inclusive), group II included 39 elderly men (from 78 to 83 years old, inclusive). The transverse, longitudinal and vertical dimensions of the cerebellum were determined. When comparing the parameters of the linear dimensions of the cerebellum in the studied age groups of men, a statistically significant decrease in all indicators in old age compared with young age was revealed (p=0.042). There was no statistically significant difference between the parameters of the longitudinal and vertical sizes of the cerebellar hemispheres in individuals of each age group (p>0.05); there is a tendency for these sizes to prevail in the right cerebellar hemisphere. The results obtained can serve as the equivalent of the age-related anatomical norm of the cerebellum in young and old men, which will make it possible to use these data in basic and clinical research, as well as in medical practice.


2021 ◽  
Vol 2 (6) ◽  
pp. 01-03
Author(s):  
Wang Xiaoying

Objective: To investigate the incidence of plicae palmatae in uterus didelphys and its morphological characteristics on MR imaging. Methods: We retrospectively collected 37 consecutive female pelvic MR images diagnosed with uterus didelphys between August 2012 and November 2020. Patients with the following conditions were excluded: (a) repeated examination; (b) poor image quality; (c) cervical disease. Axial and coronal T2-weight images and axial three-dimensional (3D) volumetric isotropic T2-weighted acquisition (VISTA) were used to evaluate the ridge of plicae palmatae (RPP). A multiplanar reformation of the cervical axis from 3D-VISTA sequence was performed to measure the height and width of RPP. Non-normal variables based on the Kruskal-Wallis H test was used for statistical analysis. A two-tailed test where P < 0.05 was considered statistically significant. Results: Twenty-six cases were finally included in the statistics. The average age was 25.7±9.0 years (range, 10-45 years). RPP was observed on both cervices in 16 patients (61.5%), only on the left cervix in 3 patients (11.5%), and only on the right cervix in 4 patients (15.4%). There were 3 cases with no RPP observed in any of their cervix (11.5%).All RPP appear symmetrically on the anterior and posterior walls of the cervix. There was no statistically significant difference in height, width, and height/width of the RPP in the left and right cervix (p>0.05). Conclusions: RPP is encountered in 88.5% patients with duplicated uterine cervices in our cohort. This incidence is similar to that reported in women with normal uterus of reproductive age.


2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Tanya Bozhkova ◽  
Nina Musurlieva ◽  
Diyan Slavchev

Introduction. The wide variety of methods for recording occlusal contacts and the contradictory data on the interpretation of the obtained markings provoked us to make a comparative laboratory study between different occlusal indicators. Purpose. Evaluation of a qualitative and quantitative method for registration of occlusal contacts in static occlusion in laboratory conditions. Materials and Methods. In completion of the objective, we designed an apparatus for registration of the occlusal contacts (AROC) in static occlusion which is used, corresponding to the MIP in clinical conditions. The occlusal indicators that were included in the study were articulating paper 100 μ, articulating foil 12 μ, and T-Scan Novus system with a sensor thickness of 100 μ. The collected primary statistical information was entered and processed with the statistical package SPSS Statistics 19.0, and the graphs were prepared using Microsoft Office 2019. We performed descriptive statistical analysis in this study. Comparisons were performed using one-way analysis of variance (ANOVA), Student’s t -test, and Pearson coefficient method. For a significance level, p < 0.05 was chosen. Result and Discussion. With quality occlusal indicators, it is possible only to visually determine the size, number, and intensity of the marked contacts. After the statistical processing of the obtained data on the number of registered contacts, a significant difference is found in the number of contacts of certain teeth (18, 24, 25, 28, 38, 35, 34, 33, 44, 45, and 48) registered with articulating paper and articulating foil. The maximum force that is reported during the study with the T-Scan system is 93.72% and the forces in the right half of the dentition are 51.7% and in the left 48.9%. To visualize the location of the registered occlusal contacts with the system, it is intraoral to use a quality indicator and we recommend the use of articulating foil. Conclusion. Based on findings from the current in vitro simulation, we can conclude that the type of occlusal indicator influences the registration of contacts, and therefore, we propose as a method of choice to achieve a balanced occlusion in clinical practice to combine the use of one conventional and one quantitative method.


10.14341/7704 ◽  
2017 ◽  
Vol 20 (2) ◽  
pp. 135-141 ◽  
Author(s):  
Elena Yur'evna Komelyagina ◽  
Eugenia Alexandrovna Kogan ◽  
Mikhail Borisovich Antsiferov

Aim. To assess the clinical and morphological characteristics of neuropathic diabetic foot ulcers (DFUn) Materials and Methods.Forty-three specimens of DFUn were analysed. Depending on the outcome, samples were divided into 2 groups: group 1healed ulcers (30 samples), group 2unhealed ulcers (13 samples). The following characteristics were analysed: age, sex, glycated haemoglobin (HbA1c), ulcer duration, time of admission to the specialised clinic, severity of neuropathy, presence of late complications, plantar localisation, percentage of necrotic tissue, granulation and fibrotic tissue and, Ki-67expression. Results. Patients were similar in age, HbA1c, severity of late complications and plantar localisation. There was a significant difference in the time of admission to the specialised clinic [50 vs 132 days, p = 0.03], percentage of granulation [61 25 vs 32 21 %, р = 0.001] and fibrotic tissue [24 24 vs 49 22 %, р = 0.002], the granulation/fibrosis coefficient [7.5 8.1 vs 1.9 4.6 (%), р = 0,02] and expression of Ki-67 [15 8 vs 21 (%), р = 0.001] between groups. A multidimensional model revealed granulation tissue as the main parameter influencing healing. The probability of healing was 1.0 if the percentage of granulation tissue was 50%. If the percentage of granulation tissue was 50%, the prognosis of healing was determined by the expression of Ki-67. When Ki-67 levels were 7%, the probability of healing was 0.75. For Ki-67 levels 7%, the probability of healing was 0.17 and the probability of not healing was 0.83. Conclusion. The time at which a patient was admitted to the specialised clinic and the percentage of granulation tissue were key factors affecting the prognosis of wound healing in DFUn.


2020 ◽  
pp. 69-74
Author(s):  
А. А. Романенко ◽  
С. Н. Деревцова

Цель - изучение качественных и количественных показателей папиллярных узоров дистальных фаланг пальцев рук у женщин пожилого возраста. Материал и методы. С помощью аппаратно-программного комплекса (АПК) «Малахит» определены типы кожного узора (дуга, радиальная петля, ульнарная петля и завиток), распространенность каждого типа на пальцах правой и левой руки, симметричность на гомологичных пальцах у 169 женщин пожилого возраста. Составлены формулы распределения для каждого типа узора на пальцах обеих рук. Статистический анализ результатов обследования проведен с использованием пакета прикладных программ SPSS 22.0. Результаты. Чаще регистрировались ульнарные петли, вторую группу по распространенности составили завитковые узоры, радиальные петли и дуги вошли в группу наиболее редких узоров. Выявлены статистически значимые билатеральные различия в распространенности завитковых и дуговых узоров на пальцах правой и левой кисти: наибольшее количество завитков зарегистрировано на пальцах правой кисти, дуговых узоров - на пальцах левой кисти. Чаще всего симметричные узоры регистрировали на V пальцах, значимо реже на II пальцах. Выводы. Изученные признаки папиллярных узоров являются маркерами, характеризующими особенности рельефа гребешковой кожи на дистальных фалангах пальцев рук у женщин пожилого возраста. Objective - to study the qualitative and quantitative indicators of papillary patterns of the elderly women distal phalanges. Material and methods. Papillary patterns were studied with the help of the «Malachite» software-hardware complex. Types of friction ridge patterns (arc, radial and ulnar loops, whorl) were determined; the prevalence of each type of pattern on all fingers of the right and left hands and the symmetry of friction ridge patterns on homologous fingers were studied in 169 elderly women. Formulas for each type of pattern on the fingers of both hands were developed. Statistical analysis of the study results was performed using the SPSS 22.0 software Results. The ulnar loops were recorded most frequently; the second most frequently found were whorls and radial loops, and radial loops and arcs were the rarest patterns. Statistically significant bilateral differences were found in the prevalence of whorls and arcs on fingers of left and right hands: the largest number of whorls was recorded on the fingers of the right hand, the largest number of arcs - on the fingers of the left hand. The symmetrical patterns were most frequently found on the fifth fingers, and significantly less frequent - on the second fingers. Conclusions. The studied features of skin patterns are markers that are characteristic for the ridged skin of the distal phalanges of elderly women.


Author(s):  
Ipsita Sahu ◽  
Sailabala Mohanty ◽  
Suchismita Pahantasingh

Background: Elderly women residing in old age home requires greater adaptability. Prevalence of depression, low self-esteem and feelings of loneliness are more among them. RGT has proven as a most effective alternative intervention especially for elderly at minimizing these above outcomes. Therefore, the present study assessed the effect of RGT on depression, self-esteem and loneliness among elderly women residing in old age home.Methods: Quantitative Research approach and quasi- experimental design was adopted. A total of 50 elderly women aged ³60yrs residing in Nirmal Hriday, Missionaries of charity old age home, Bhubaneswar were selected for experimental (N=25) and control (N=25) group by using purposive sampling. Baseline data were collected by using Socio demographic data Performa, Geriatric depression scale, Rosenberg self-esteem scale and UCLA loneliness scale after getting written informed consent from each participant. Total 3 biweekly reminiscence sessions for 45 minutes was held by dividing the experimental group into 4 groups.Results: Analysis revealed that after RGT, the experimental group showed that level of depression was decreased (before intervention 10.08±1.41 and after intervention 6.36±1.38), self-esteem was improved (before intervention 23.4±2.69 and after intervention 29.56±2.58) and loneliness was reduced (before intervention 36.92±4.57 and after intervention 20.96±5.09) significantly. There was a statistically significant difference found in depression, self-esteem and loneliness scores among experimental group as compared to control group (p<0.0001).Conclusions: On the findings of the study it was concluded that RGT yielded positive effects among elderly women residing in old age home.


2016 ◽  
Vol 97 (4) ◽  
pp. 550-555
Author(s):  
A P Dmitrenko

Aim. To determine lateral differences of breast cancer proliferative activity Ki-67.Methods. According to immunohistochemical study protocols analysis of material of 500 patients with breast cancer was conducted. In primary tumors estrogen and progesterone receptors expression, Ki-67, C-erbB-2 was studied.Results.Using two-way analysis of variance, it was found that Ki-67 index was significantly influenced by both side of the tumor lesion (p=0.009) and age of patients (p=0.0002). A higher Ki-67 corresponded to right-sided cancer localization. Statistically significant age differences of Ki-67 index are marked only in right-sided cancer (pConclusion. Statistically significant difference of Ki-67 index in right- and left-sided breast cancer was found, significantly higher Ki-67 was detected in the right-sided tumors, Ki-67 are present only in patients before 60 years.


1983 ◽  
Vol 245 (5) ◽  
pp. H891-H896 ◽  
Author(s):  
L. H. Silver ◽  
E. L. Hemwall ◽  
T. A. Marino ◽  
S. R. Houser

A technique has been developed for isolating a high yield of Ca2+-tolerant rod-shaped myocytes from the right and left ventricles of cat myocardial tissue. Myocytes were prepared by retrograde perfusion of the coronary arteries via the aorta with a nominally Ca2+-free (20-30 microM) modified Krebs-Henseleit buffer containing 0.12% collagenase. After exposure to physiological levels of Ca2+ (1-2.5 mM), the cells retained rod-shaped morphology, exhibited clear cross striations, and excluded the dye trypan blue (0.4%). Initial percents of viable Ca2+-tolerant rod-shaped cells were 58.6 +/- 3.4 (SE) and 51.8 +/- 3.5 for right and left ventricular cells, respectively. Viability studies demonstrated that these values decreased approximately 10% at the conclusion of a 2-h incubation in 1 mM Ca2+. The total numbers of rod-shaped myocytes obtained were 4.48 X 10(7) and 3.89 X 10(7) in nominal (8-10 microM) and 1 mM Ca2+-containing buffer, respectively. A total of 3.44 +/- 0.40 X 10(6) rod-shaped Ca2+-tolerant myocytes was initially isolated per gram of tissue wet weight. Measurements of cell length, width, and sarcomere length demonstrated no significant differences between right and left ventricular cells suspended in nominal (8-10 microM) and 1 mM Ca2+-containing buffer. No significant difference was found in the percent of binucleate cells when right and left ventricular myocytes were compared. These results demonstrate that a stable population of Ca2+-tolerant myocytes with similar morphological characteristics can be isolated from the right and left ventricles of cat myocardium.


2021 ◽  
Vol 29 (1) ◽  
pp. 43-48
Author(s):  
Anna M. Nekrasova ◽  
Irina A. Balandina

The study of the age-related anatomical variability, its exact morphological characteristics in adulthood, established using modern research methods, are needed, which can serve as a criterion for a conditional norm. The aim of the study is to determine the macro- and micro-morphometric parameters of the ampulla of the fallopian tubes of women in the first period of adulthood using prosection material and their morphological characteristics. The ampulla of both fallopian tubes of 44 nulliparous and 58 giving birth women of the first period of adulthood (from 21 to 35 years) were examined. Organometric, histological, immunohistochemical and macro- and micro-morphometric research methods were used. It determined the length of the ampoules, their outer diameter at the junction of the isthmus in the ampoule, in the central part of the ampoule and at the junction of the ampoule in the funnel. Histological sections were stained with hematoxylin and eosin, picro fuchsin according to van Gieson. In the immunohistochemical study of the samples, antibodies against vimentin and the CD68 marker were used. The area of ​​the lumen of the ampulla of the fallopian tube and the area of ​​its wall was calculated, and the circumference of the epithelial lining was measured. As a result, it was found that the outer diameter of the fallopian tubes at the junction of the isthmus into the ampulla and the ampoule into the funnel, as well as in the central part of the ampoule, is characterized by the absence of a statistically significant difference in parameters in nulliparous and giving birth women. The histological picture of the ampulla of the fallopian tubes both in nulliparous and in women giving birth in the first period of adulthood is of the same type and is represented by a mucous membrane that forms many thin papillary folds, internal circular and external longitudinal layers of smooth muscle tissue of the muscular membrane and the serous membrane. The detection in the tissues of the ampulla of the fallopian tubes in nulliparous and giving birth women in a moderate amount of CD68-immunopositive macrophages, the concentration of which increases in the epithelium and near it, as well as the expression of vimentin in the vessel walls and individual fibroblasts, indicates the presence of physiological tissue regeneration processes. Analysis of the indicators of the areas of the lumen of the ampoule and its wall at the median section, as well as the circumference of the epithelial lining, allows us to conclude that these parameters predominate in the right fallopian tube.


Crisis ◽  
2001 ◽  
Vol 22 (1) ◽  
pp. 15-19 ◽  
Author(s):  
Andrée Fortin ◽  
Sylvie Lapierre ◽  
Jacques Baillargeon ◽  
Réal Labelle ◽  
Micheline Dubé ◽  
...  

The right to self-determination is central to the current debate on rational suicide in old age. The goal of this exploratory study was to assess the presence of self-determination in suicidal institutionalized elderly persons. Eleven elderly persons with serious suicidal ideations were matched according to age, sex, and civil status with 11 nonsuicidal persons. The results indicated that suicidal persons did not differ from nonsuicidal persons in level of self-determination. There was, however, a significant difference between groups on the social subscale. Suicidal elderly persons did not seem to take others into account when making a decision or taking action. The results are discussed from a suicide-prevention perspective.


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