Anti-Aging Drugs – Prospect of Longer Life?

2018 ◽  
Vol 25 (17) ◽  
pp. 1946-1953 ◽  
Author(s):  
Blanka Klimova ◽  
Michal Novotny ◽  
Kamil Kuca
Keyword(s):  
Aging Process ◽  
Human Life ◽  
Special Focus ◽  
Human Beings ◽  
Organ Function ◽  
Drug Candidates ◽  
Randomized Control ◽  
Physical Resistance ◽  
Prolonged Life Expectancy

Background: Aging is a natural part of human life. However, recent discoveries indicate that pharmacological approaches used for the improvement and possibly, for the delay of the aging process, might shed a new light on this topic. This might obviously contribute to the extension of the active life of older people and maintenance of their quality of life, which could consequently reduce both social and economic burden of each country, especially the developed ones. Objective: The purpose of this study is to explore pharmacological discoveries which may help to the delay or improvement of the aging process. More specifically, the authors focus on three anti-aging drugs candidates: metformin, rapamycin and resveratrol and one anti-aging component NAD+ precursors whose randomized control trials on animals have appeared to provide some efficacy in this respect and they seem to be promising in the aging process of human beings. Methods: This was done by conducting a literature review of available sources describing the issue of aging process with special focus on those anti-aging drug candidates. Results: The results of this study indicate that promising anti-aging candidates seem to be metformin, especially as far as cardiovascular or cancer mortality is concerned, and NAD+ precursors since they appear to promote better organ function, increased physical resistance, disease resistance and prolonged life expectancy. Conclusion: There is a call for more longitudinal clinical trials, which would prove the efficacy of the promising anti-aging drugs candidates in humans.

The Prospects for Holy War

2016 ◽  
Vol 36 (2) ◽  
pp. 195-217
Author(s):  
Terence J. Martin
Keyword(s):  
Quality Of Life ◽  
Human Life ◽  
Human Beings ◽  
Literary Creation ◽  
Specific Question ◽  
Holy War ◽  
Moral Quality

This essay offers a reading of “A Most Useful Discussion Concerning Proposals for War against the Turks.” What we have in the “Useful Discussion” is a mock consultation, a literary creation in which Erasmus appears to offer judicious advice on how Christendom might wage a successful war against the Turks, only to undercut the very prospects for such a war by means of various strategies of indirection, hesitation, and ironic reversal. Erasmus works critically and ironically on several levels at once—unsettling the dogmatism of war-mongers, surprising Luther and his critics, frustrating the interests of the powerful, and nudging everyone to think seriously about fundamental questions of human life. Though the “Useful Discussion” may appear to address a specific question about a specific war, it in fact speaks—in its pendular and ironic manner—to more basic questions, inviting readers to reflect with amazement and remorse upon the numbness and deafness of human beings before God; and, on that basis, to work to enhance the moral quality of life.

THE PROBLEMS OF PESANTREN EDUCATION IN IMPROVING HUMAN ACADEMIC QUALITY IN THE GLOBAL-MULTICULTURAL ERA

2021 ◽  
Vol 9 (1) ◽  
pp. 165-186
Author(s):  
Qolbi Khoiri ◽  
Ani Aryati
Keyword(s):  
Human Resource ◽  
Strong Influence ◽  
Human Life ◽  
Scientific Work ◽  
Human Beings ◽  
Academic Quality ◽  
Community Members ◽  
The West ◽  
Left Behind

This scientific work outlines the obstacles facing Pesantren education in improving academic human beings' global-multicultural era. Pesantren global currents can cause paradox or symptoms of counter-morality. So does the pattern of life in the West, even significantly affect the moral decay, moral and human behavior. With this condition, the influence is considerable on human life, both physical and spiritual. Thus, Pesantren education faced various challenges with developing education models in the era of globalization implemented by community members, such as system problems, human resource problems, and curriculum development. Therefore, to improve the quality of academic humanity in the global-multicultural era, Pesantren have problems exploring all the resources they have. Because Pesantren education is less concerned with the situation, human resource problem, a strong influence of western culture in domination and imperialization of information, and the current culture of globalization can lead to paradox or symptoms of counter-morality. With this problem, a Pesantren can devote all the power, effort, and ability to innovate. Finding something new can help a student's life for the better. However, if Pesantren does not dig all his skills, he will be left behind by the ever-evolving era.

scholarly journals TRABALHO DOCENTE: REFLEXÕES SOBRE A SAÚDE E O SOFRIMENTO PSÍQUICO DO PROFESSOR

2020 ◽  
Vol 1 ◽  
pp. 16 ◽  
Author(s):  
Glaé Corrêa Machado ◽  
Andréia Mendes dos Santos ◽  
Renata Santos da Silva
Keyword(s):  
Quality Of Life ◽  
Interpersonal Relationships ◽  
Basic Education ◽  
Human Life ◽  
Work Conditions ◽  
Daily Routine ◽  
Human Beings ◽  
Work Activity ◽  
Starting Point

Este texto versa sobre as implicações do trabalho docente na saúde e qualidade de vida do professor. A partir da concepção de que o trabalho é uma atividade fundamental para o desenvolvimento dos seres humanos, consideramos que o ato de trabalhar transforma a si mesmo no e pelo trabalho, relacionando-se diretamente com identidade social. Por outro lado, observa-se também que a centralidade que este ocupa na rotina cotidiana da vida humana, em especial da categoria, impõe uma relação conflituosa, pois, apesar de carregada de diferentes investimentos, as condições e as exigências do trabalho também são causas de doenças físicas e mentais. Nesta atividade laboral, articulam-se diretamente relações interpessoais, envolvendo experiências emocionais constantes. É um campo profissional onde a subjetividade dos afetos emerge no cotidiano, em relações diárias, envolvendo, na maioria das situações, crianças e jovens em desenvolvimento. Como tese, sustenta-se que estes movimentos, que possuem reflexo direto na organização dos processos de trabalho, produzem graves consequências sobre a saúde dos professores, em seus aspectos físicos ou psíquicos. Como ponto de partida, consideramos os resultados de um estudo que analisou aspectos referentes à saúde dos docentes da educação básica de sete estados brasileiros, entre outros, articulando uma discussão com uma análise qualitativa de diários de estágio em Psicologia Escolar. Nossas considerações ampliam as questões que se impõe ao docente na contemporaneidade e que lhes causam desgaste e consequente sofrimento psíquico.Palavras-chave: Trabalho docente. Saúde do trabalhador. Qualidade de vida.ABSTRACTThis text deals with the implications of teaching work on the teacher's health and quality of life. From the conception that work is a fundamental activity for the development of human beings, we consider that the act of working transforms itself into and through work, relating directly to social identity. On the other hand, it is also observed that the centrality it occupies in the daily routine of human life, especially in the category, imposes a conflicting relationship, because despite being loaded with different investments, work conditions and demands are also causes of illness. physical and mental. In this work activity, interpersonal relationships are directly articulated, involving constant emotional experiences. It is a professional field where the subjectivity of affections emerges in daily life, in daily relationships, involving in most situations children and young people in development. As a thesis, it is argued that these movements, which have a direct reflection on the organization of work processes, have serious consequences on teachers' health, in their physical or mental aspects. As a starting point, we consider the results of a study that analyzed aspects related to the health of basic education teachers from seven Brazilian states, among others, articulating a discussion with a qualitative analysis of internship diaries in School Psychology. Our considerations broaden the questions that are imposed on the teacher in contemporary times that cause them to wear and consequent psychic suffering.Keywords: Teaching work. Worker's health. Quality of life.

scholarly journals The Concept of Peace in the Al-Qur'an Pespective

2018 ◽  
Vol 1 (3) ◽  
pp. 30-41
Author(s):  
Mukhtar Nuhung ◽  
Abdul Rahim
Keyword(s):  
Qualitative Data ◽  
Human Life ◽  
Human Beings ◽  
Peace Of Mind ◽  
Know How ◽  
Textual Interpretation ◽  
Library Research ◽  
Or Groups ◽  
The Stability

Conflicts, disputes, and acts of terrorism have become a daily scene, both in the nature of individuals, communities, tribes, religions, and even between nations. Al-Quran as a way of live always leads Muslims to live safely and peace away from the conflict. Thus, the main problem arising from this research is how the concept of peace in the Qur'an. This discussion aims to know how the nature of peace, how the form of peace, and how the goals and benefits of peace according to the Qur'an. It is intended to provide a comprehensive understanding of the concept of peace that exists in the Quran. The research is a library research which is qualitative. Data and information obtained through several literatures were analyzed using content analysis. The approach used was the "science of interpretation" with the method maud} u> i> / thematic. In interpreting the data, some interpretation techniques were used: textual interpretation, linguistic, socio-historical, systemic, and logical interpretation, The results show that there were verses in the Qur'an that explains about peace meaning human being free from conflict and war, free from civil instability and free from disturbance of riot, violence and so on. The concept of the Quran on peace is the order of peace (is} la> h}), and the command to reconcile conflicting people or groups. The object of peace is humanity as a whole. Peace aims to stop conflict between human beings. Both reconcile directly between the conflict, as well as peace through the mediator. The benefits of peace are; ensuring the stability of security and economy, the creation of a sense of peace of mind in marriage, community and nation, The implications of the study emphasize that the study of verses on the concept of peace in the Qur'an includes the needs of human life in national and state society, so it needs to be developed primarily in the current era of globalization, because the analysis of the verses of peace can provide motivation, inspiration and innovative spirit to elaborate the values of togetherness in living life in various aspects which in turn mankind can improve the quality of life in qur'ani. This study is not only limited to knowing and understanding but by applying it in everyday life by minimizing the occurrence of conflict, violence, discrimination, injustice so as to realize safe and peaceful people who love togetherness in knitting life in this world that is safe, happy and prosperous .

Protest Views of Singer

PEDIATRICS ◽  
1984 ◽  
Vol 73 (2) ◽  
pp. 260-261
Author(s):  
ALBERT S. CALLIE
Keyword(s):  
Quality Of Life ◽  
Special Form ◽  
Human Life ◽  
Image Of God ◽  
Human Beings ◽  
Philosophical Foundations ◽  
Sanctity Of Life ◽  
The Image Of God ◽  
Made In

To the Editor.— Singer, in his article "Sanctity of Life or Quality of Life?" (Pediatrics 1983;72:128-129) has rejected the "sanctity-of-life view"—as he defines it. He calls it "the obsolete and erroneous notion of the sanctity of all human life." He states that "the philosophical foundations of this view have been knocked asunder." He adds "We can no longer base our ethics on the idea that human beings are a special form of creation made in the image of God."

scholarly journals MEMBANGUN FIQH EKOLOGI BERBASIS MASLAHAH

2016 ◽  
Vol 10 (1) ◽  
pp. 145-162
Author(s):  
Rahwan Rahwan
Keyword(s):  
Islamic Law ◽  
Code Of Ethics ◽  
Human Life ◽  
Human Beings ◽  
Human Relationships ◽  
High Concern ◽  
General Principles Of Law ◽  
The Right ◽  
Conducive Environment

Talking about the environment, it means talking about the environment around us, covering the entire ecosystem. Environment consists of flora and fauna, biotic and abiotic (and inanimate objects). Life environment are interdependent with each other. Human small part of the environment. This environment will determine the fate of human life. Will provide a conducive environment and secure quality of life, on the contrary, if the environment is less conducive it will result in insecure or lacking in quality even really threaten the safety of humans and the entire ecosystem in the world. Fiqh as Islamic law governing the pattern of human relationships with God and neighbor, and also discuss the human relationship with the environment. The share issue fiqh in an effort to maintain harmonious environment by providing rules or code of ethics of human relationships with the environment. As the ban on harming the environment and the obligation of preserving the environment. This environmental management is based to the proposition - proposition tipsily, namely al-Qur'an, al-Hadith, and the general principles of law legeslasi. When fiqh took part in preserving the environment, then the whole mukallaf particular awareness of environmental issues related to land, air and sea. So they have a high concern for the environment. Giving rights owned by the environment, such as the right to life and the right to expand, not plunder and exploit. With so environment remain stable, beautiful and conducive. Along with other human beings be peaceful. Based on the above views of researchers seeks to conduct research in matters of environmental jurisprudence. With the aim of formulating a comprehensive environmental fiqh, systematic, and akuntebel and can deal with the issue of global warming.

scholarly journals Strategies for organizing and improving urban space (Case study: from Mahbas intersection to Mission intersection, Ahmad Shah Baba Mineh town)

2021 ◽  
Vol 2 (3) ◽  
pp. 36-48
Author(s):  
Parviz Akhtar Jaheed ◽  
Hamid Reza Ameri Siahvi ◽  
Asadollah Movahedi
Keyword(s):  
Urban Space ◽  
Public Transportation ◽  
Human Life ◽  
Public Spaces ◽  
Human Beings ◽  
Space Case ◽  
Transportation Routes ◽  
The City

The city is a place for human life, where all the components necessary for human life must be present in the city so that human beings can live physically and mentally in peace. The cities of Afghanistan, especially the residential town of Ahmad Shah Baba Mina, are facing many problems. The purpose of this research was to investigate the problems of this town and to provide suggestions for its improvement and organization. The method of this research is library, perception and field considerations. Targeted interviews were conducted with 12 people who were familiar with urban design and urban planning issues. The analysis was performed by SWOT technique and space arrangement. The research results show that this town is faced with challenges such as transportation problems, lack of proper sidewalks, lack of urban furniture, visual personality and identity issues, environmental challenges, lack of proper distribution of land uses, congestion in public spaces. And there are issues that have changed the physical appearance and public spaces. During this research, suggestions for setting up public transportation routes, setting up vendors and new neighborhoods for their activities, Create special bike lanes, Improving the quality of public spaces has been provided to create public activities, improve public spaces as well as promote sensory richness.

scholarly journals ANALYSIS OF THE QUALITY OF LIFE IN THE REPUBLIC OF NORTH MACEDONIA

2019 ◽  
Vol 34 (1) ◽  
pp. 49-54
Author(s):  
Irena Lekoska
Keyword(s):  
Quality Of Life ◽  
Clinical Medicine ◽  
Global Financial Crisis ◽  
Human Life ◽  
Complex Problem ◽  
Living Standard ◽  
Special Focus ◽  
Quality Life ◽  
Life Itself

Nowadays, when the world economies are not yet completely released from the destructive effects of the last global financial crisis and still are feeling intensely the shocks caused by daily economic events, the dilemma arises whether humanity as a whole has a satisfactory quality of life, or whether it lives within dignified human existence. This dilemma is particularly present in small emerging economies, with a special focus on transitional economies, which are still at the beginning of a bumpy road to economic development and prosperity.In recent years, the issue of quality of life has become quite an interesting topic and has been the subject of research in the fields of economics, psychology, clinical medicine, health care, philosophy and sociological sciences. Understanding and evaluating this concept has gone through a long period of evolution. Over the years, the term of quality of life, standard of living, and welfare have been perceived as identical terms, even today their connection is so strong that it is almost impossible to talk about one term without mentioning the others.The question of the quality of human life is an inexhaustible source, so, that is, the inspiration of numerous scientists from all fields of science, with a particular emphasis on economists. To perceive or measure the quality of human life is a complex problem that can never be completely exhausted or clarified with certainty. This is due to the fact that the term "quality of life" itself has a multidimensional character and it is extremely difficult to find all the indicators that would explain this concept and determine its true value.Therefore, the goal of this paper is to analyze certain economic indicators that will enable us to make an adequate assessment, or measure the quality of life. The main emphasis of the paper is on the evaluation of relevant indicators of quality of life in North Macedonia and based on comparative analysis has been concluded that our country is positioned on the lower margins of dignified and quality life. Because of this situation, certain measures have been taken, in order to identify the most important strategic priorities of our country. The realization of these strategic priorities and the appropriate allocation of budget funds will ensure higher growth rates of the Macedonian economy in the coming period, with simultaneous improving of the quality of life and living standard of the population.

Using Economic Instruments for Urban Environment Management in Vietnam

China Report ◽  
2017 ◽  
Vol 53 (3) ◽  
pp. 386-399 ◽  
Author(s):  
Nguyen Thi Ngoc
Keyword(s):  
Urban Environment ◽  
Urban Areas ◽  
Load Capacity ◽  
Human Life ◽  
Global Scale ◽  
Human Beings ◽  
Economic Instruments ◽  
Environment Management ◽  
The Government

The environment and the economy are basic and inseparable elements. The environment is the locus and support for the activities of human life. These activities are related to the creation and supply of resources necessary for the economy. They generate large amounts of waste, while the load capacity of the environment is limited. When economic operations go beyond certain limits, then the environment cannot sustain them. This could lead to economic crisis on a global scale. The problem is how to protect the environment, maintain economic operations and improve the lives of human beings, or in other words, find the ways to harmonise environmental factors with the needs of the economy. Vietnam and other developing nations are facing serious problems of environmental degradation, especially in urban areas. Many solutions have been tried, of which the use of economic instruments has received much attention on the part of the government and leaders of Vietnam. This article focuses on the use of economic instruments in urban environment management in Vietnam. The objectives of this article are to explore how economic instruments are being used for urban environment management and to point out the issues and difficulties emerging in the process of using this tool to control environmental pollution and to improve the quality of the environment.

scholarly journals Jakość życia seniorów w pedagogicznej odsłonie

2020 ◽  
Vol 17 ◽  
pp. 217-230
Author(s):  
Aldona Rumińska-Szalska
Keyword(s):  
Quality Of Life ◽  
Elderly People ◽  
Old Age ◽  
Aging Process ◽  
Human Life ◽  
The Elderly ◽  
Point Of View ◽  
Social Environments ◽  
Priority Task

In the light of contemporary socio-demographic changes and humanistic ide-as, the issues of aging and old age gain noteworthy signifi cance. Everyone, especially the elderly, should be treated subjectively due to the consequences of the aging process. Taking into account the sense of quality of life of an el-derly person becomes a priority task and challenge for social environments in which the senior lives. This problem seems to be interesting, especially from the pedagogical point of view in the context of improvement, development, self-creation and accomplishment. Research on the quality of life of seniors is widely popular among Polish and foreign authors. It results from the thor-oughly represented science by researchers and their cognitive interests. The results od those studies should be updated and disseminated to increase the meaning and quality of human life. The article is a review of selected pedagog-ical concepts regarding the sense of quality of life among elderly people and conducted research on the topic.

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