Biological Activities and Pharmacological Applications of Cyclodextrins Complexed with Essential Oils and Their Volatile Components: A Systematic Review

AbstractThe rich and diversified Malaysian flora represents an excellent resource of new chemical structures with biological activities. The genus Xylopia L. includes aromatic plants that have both nutritional and medicinal uses. This study aims to contribute with information about the volatile components of three Xylopia species essential oils: Xylopia frutescens, Xylopia ferruginea, and Xylopia magna. In this study, essential oils were extracted from the leaves by a hydrodistillation process. The identification of the essential oil components was performed by gas chromatography (GC-FID) and gas chromatography–coupled mass spectrometry (GC-MS). The major components of the essential oils from X. frutescens were bicyclogermacrene (22.8%), germacrene D (14.2%), elemol (12.8%), and guaiol (12.8%), whereas components of the essential oils from X. magna were germacrene D (35.9%), bicyclogermacrene (22.8%), and spathulenol (11.1%). The X. ferruginea oil was dominated by bicyclogermacrene (23.6%), elemol (13.7%), guaiol (13.4%), and germacrene D (12.3%).

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Chemical Composition and Biological Activities of Essential Oils of Curcuma Species

Nutrients ◽

10.3390/nu10091196 ◽

2018 ◽

Vol 10 (9) ◽

pp. 1196 ◽

Cited By ~ 46

Author(s):

Noura Dosoky ◽

William Setzer

Keyword(s):

Essential Oils ◽

Biological Activities ◽

Volatile Components ◽

Health Maintenance ◽

Volatile Chemicals ◽

Oil Companies ◽

Beneficial Effects ◽

Inflammatory Conditions ◽

Potential Safety ◽

Health Related

Members of the genus Curcuma L. have been used in traditional medicine for centuries for treating gastrointestinal disorders, pain, inflammatory conditions, wounds, and for cancer prevention and antiaging, among others. Many of the biological activities of Curcuma species can be attributed to nonvolatile curcuminoids, but these plants also produce volatile chemicals. Essential oils, in general, have shown numerous beneficial effects for health maintenance and treatment of diseases. Essential oils from Curcuma spp., particularly C. longa, have demonstrated various health-related biological activities and several essential oil companies have recently marketed Curcuma oils. This review summarizes the volatile components of various Curcuma species, the biological activities of Curcuma essential oils, and potential safety concerns of Curcuma essential oils and their components.

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A Survey on Chemical Constituents and Indications of Aromatic Waters Soft Drinks (Hydrosols) Used in Persian Nutrition Culture and Folk Medicine for Neurological Disorders and Mental Health

Journal of Evidence-Based Complementary & Alternative Medicine ◽

10.1177/2156587217714145 ◽

2017 ◽

Vol 22 (4) ◽

pp. 744-752 ◽

Cited By ~ 6

Author(s):

Azadeh Hamedi ◽

Ardalan Pasdaran ◽

Zahra Zebarjad ◽

Mahmoodreza Moein

Keyword(s):

Cluster Analysis ◽

Essential Oils ◽

Biological Activities ◽

Chemical Constituents ◽

Water Soluble ◽

Gas Chromatography Mass Spectrometry ◽

Volatile Components ◽

Health Maintenance ◽

Lemon Balm ◽

Dog Rose

In Persian nutrition culture, drinking aromatic waters (hydrosols, distillate) has a long history as functional beverages or therapeutic remedies. The co-distilled water with essential oils, which contains partial amounts of more water-soluble volatile compounds are diluted and used as beverages. Since the solubility of volatile components is different in water, the overall composition, and thus the biological activities of aromatic waters seem to be different from the essential oils they were co-distilled with. Despite the essential oils, chemical constituents of many aromatic waters have not been evaluated scientifically. This research investigated hydrosols used for mental and neurological health maintenance in Persian nutrition culture and their chemical constituents. Constitutions of these hydrosols were extracted by liquid/liquid extraction method and identified by gas chromatography–mass spectrometry. Furthermore, cluster analysis was used to evaluate the relevance of these hydrosols chemical constituents. About 93 compounds were identified from 20 aromatic waters. the major or second major constituents were thymol (azarol howthorn, frankincense, lemon balm, valerian, shadab), phenethyl alcohol (damask rose, dog-rose, starflower), carvacrol (basil, creeping buttercup, lemon balm); eugenol (shadab, dog-rose, starflower, basil), camphor (yarrow and wormwood), carvone (oriental plane), caryophyllene (cuminum), cinnamaldehyde (Chinese cinnamon), p-cymen-7-ol (musk willow), limonene (lemon verbena), linalool and α-terpineol (bitter orange), menthol (date palm) and methyl 5-vinylnicotinate (olive). Although, these hydrosols prepared from plants belong to different genus and families, but cluster analysis showed obvious similarities between their chemical constituents. Results of this investigation showed in many cases that the constituents of aromatic waters are different from the pure essential oil.

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Essential Oils from Annonaceae Species from Brazil: A Systematic Review of Their Phytochemistry, and Biological Activities

International Journal of Molecular Sciences ◽

10.3390/ijms222212140 ◽

2021 ◽

Vol 22 (22) ◽

pp. 12140

Author(s):

Márcia Moraes Cascaes ◽

Odirleny dos Santos Carneiro ◽

Lidiane Diniz do Nascimento ◽

Ângelo Antônio Barbosa de Moraes ◽

Mozaniel Santana de Oliveira ◽

...

Keyword(s):

Systematic Review ◽

Essential Oils ◽

Raw Materials ◽

Biological Activities ◽

Biological Effects ◽

Economic Value ◽

Folk Medicine ◽

Cytotoxic Activities ◽

Reference Drug ◽

Annona Glabra

The present work involves a systematic review of the chemical composition and biological effects of essential oils from the Annonaceae species collected in Brazil from 2011 to 2021. Annonaceae is one of the most important botanical families in Brazil, as some species have economic value in the market as local and international fruit. In addition, the species have useful applications in several areas—for instance, as raw materials for use in cosmetics and perfumery and as medicinal plants. In folk medicine, species such as Annona glabra L. and Xylopia sericea A. St.-Hil. are used to treat diseases such as rheumatism and malaria. The species of Annonaceae are an important source of essential oils and are rich in compounds belonging to the classes of mono and sesquiterpenes; of these compounds, α-pinene, β-pinene, limonene, (E)-caryophyllene, bicyclogermacrene, caryophyllene oxide, germacrene D, spathulenol, and β-elemene are the most abundant. The antimicrobial, anti-inflammatory, antileishmania, antioxidant, antiproliferative, cytotoxic, larvicidal, trypanocidal, and antimalarial activities of essential oils from the Annonaceae species in Brazil have been described in previous research, with the most studies on this topic being related to their antiproliferative or cytotoxic activities. In some studies, it was observed that the biological activity reported for these essential oils was superior to that of drugs available on the market, as is the case of the essential oil of the species Guatteria punctata (Aubl.) R. A. Howard., which showed a trypanocidal effect that was 34 times stronger than that of the reference drug benznidazol.

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Chemical Composition and Biological Activities of Essential Oils in the Family Lauraceae: A Systematic Review of the Literature

Planta Medica ◽

10.1055/a-0943-1908 ◽

2019 ◽

Vol 85 (13) ◽

pp. 1054-1072 ◽

Cited By ~ 7

Author(s):

Carolina Sette Barbosa Damasceno ◽

Natasha Tiemi Fabri Higaki ◽

Josiane de Fátima Gaspari Dias ◽

Marilis Dallarmi Miguel ◽

Obdulio Gomes Miguel

Keyword(s):

Systematic Review ◽

Biological Activity ◽

Chemical Composition ◽

Essential Oil ◽

Essential Oils ◽

Web Of Science ◽

Biological Activities ◽

Review Of The Literature ◽

Inclusion Criteria ◽

The Family

AbstractThe Lauraceae family is predominantly found in Asia and in the rainforests of the Americas, and consists mostly of aromatic trees. Being an essential oil producer, this family is used in the food, pharmaceutical, and cosmetic industries. This work presents a systematic review of the chemical composition and bioactivity of the essential oils from the Lauraceae family. Medline, Scielo, Web of Science, Lilacs, and Scopus were employed to identify articles published between 2000 and 2018, using “Lauraceae”, “essential oil”, and “biological activity” as key words. From 177 studies identified, 53 met the inclusion criteria. These studies indicated a predominance of the compounds β-caryophyllene and 1,8-cineole in Lauraceae species, and highlighted the antioxidant, antifungal, antibacterial, and anti-inflammatory activities. Essential oils extracted from this family thus have high potential for pharmacological applications.

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Phytochemical aspects and biological activities of essential oil of species of the family Canellaceae: A review

Plant Science Today ◽

10.14719/pst.2019.6.3.585 ◽

2019 ◽

Vol 6 (3) ◽

pp. 315-320 ◽

Cited By ~ 1

Author(s):

Júlia Assunção de Castro Oliveira ◽

Rafaela Karin de Lima ◽

Erica Alves Marques ◽

Manuel Losada Gavilanes

Keyword(s):

Systematic Review ◽

Essential Oil ◽

Essential Oils ◽

Web Of Science ◽

Biological Activities ◽

Point Of View ◽

Phytochemical Analysis ◽

The Family ◽

New Research

Survey have proven the popular Canellaceae family use to treat various diseases such as: muscular pains, infections, stomatitis, anti-malaric, healing, among others. The main use of these species is in the extracts form and essential oils extracted from the leaves and stem. Highlighting the importance of this family on the pharmacological point of view and the fact that few studies in the literature have reported the characterization of the essential oils compounds and their respective biological activities. The objective of this study was to carry out a systematic review of previous studies on essential oils of the Canellaceae family species and their biological activities. The databases Scopus, Web of Science and PubMed were used for the search and a bibliographical manager was used. A total of 143 files were analyzed, of which 21 presented the phytochemical analysis and / or essential oils biological activities of these species. Few species have been studied so far, such as Canella winterana, Cinnamosma fragans, Cinnamosma madagascariensis, Cinnamodendron dinisii. It can be observed that the major constituents for these species essential oils were: 1,8-cineol, linalool, limonene, alpha and beta-pinene. And that the main proven activities were: antibiotic, antifungal, insecticide, larvicide, trypanocidal, cytotoxic, molluscicide, immunomodulatory, anti-inflammatory and anticonvulcionate. From this literature review, it was possible to identify species that have not yet started studies and possible activities of their essential oils, mainly due to the almost homogeneous presence of the major constituents, making possible new research as well as projects and programs.

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Biological Activities of Essential Oils

Planta Medica ◽

10.1055/s-0031-1282081 ◽

2011 ◽

Vol 77 (12) ◽

Author(s):

G Buchbauer

Keyword(s):

Essential Oils ◽

Biological Activities

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The Genus Haplophyllum Juss.: Phytochemistry and Bioactivities—A Review

Molecules ◽

10.3390/molecules26154664 ◽

2021 ◽

Vol 26 (15) ◽

pp. 4664

Author(s):

Majid Mohammadhosseini ◽

Alessandro Venditti ◽

Claudio Frezza ◽

Mauro Serafini ◽

Armandodoriano Bianco ◽

...

Keyword(s):

Organic Acids ◽

Essential Oils ◽

Web Of Science ◽

Biological Activities ◽

Scientific Information ◽

Comprehensive Review ◽

Scientific Databases ◽

Organic Extracts ◽

Chemical Profiles ◽

Therapeutic Properties

Herein, a comprehensive review is given focusing on the chemical profiles of the essential oils (EOs), non-volatile compounds, ethnobotany, and biological activities of different Haplophyllum (Rutaceae family) species. To gather the relevant data, all the scientific databases, including Scopus, ISI-WOS (Institute of Scientific Information-Web of Science), and PubMed and highly esteemed publishers such as Elsevier, Springer, Taylor and Francis, etc., were systematically retrieved and reviewed. A wide array of valuable groups of natural compounds, e.g., terpenoids, coumarins, alkaloids, lignans, flavonoids, and organic acids have been isolated and subsequently characterized in different organic extracts of a number of Haplophyllum species. In addition, some remarkable antimicrobial, antifungal, anti-inflammatory, anticancer, cytotoxic, antileishmanial, and antialgal effects as well as promising remedial therapeutic properties have been well-documented for some species of the genus Haplophyllum.

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Rose Flowers—A Delicate Perfume or a Natural Healer?

Biomolecules ◽

10.3390/biom11010127 ◽

2021 ◽

Vol 11 (1) ◽

pp. 127

Author(s):

Milka Mileva ◽

Yana Ilieva ◽

Gabriele Jovtchev ◽

Svetla Gateva ◽

Maya Margaritova Zaharieva ◽

...

Keyword(s):

Essential Oils ◽

Food Industry ◽

Raw Materials ◽

Biological Activities ◽

Biological Properties ◽

Rosa Damascena ◽

Oil Sand ◽

Rosa Gallica ◽

Therapeutic Properties ◽

Phytochemical Profile

Plants from the Rosacea family are rich in natural molecules with beneficial biological properties, and they are widely appreciated and used in the food industry, perfumery, and cosmetics. In this review, we are considering Rosa damascena Mill., Rosa alba L., Rosa centifolia L., and Rosa gallica L. as raw materials important for producing commercial products, analyzing and comparing the main biological activities of their essential oils, hydrolates, and extracts. A literature search was performed to find materials describing (i) botanical characteristics; (ii) the phytochemical profile; and (iii) biological properties of the essential oil sand extracts of these so called “old roses” that are cultivated in Bulgaria, Turkey, India, and the Middle East. The information used is from databases PubMed, Science Direct, and Google Scholar. Roses have beneficial healing properties due to their richness of beneficial components, the secondary metabolites as flavonoids (e.g., flavones, flavonols, anthocyanins), fragrant components (essential oils, e.g., monoterpenes, sesquiterpenes), and hydrolysable and condensed tannins. Rose essential oils and extracts with their therapeutic properties—as respiratory antiseptics, anti-inflammatories, mucolytics, expectorants, decongestants, and antioxidants—are able to act as symptomatic prophylactics and drugs, and in this way alleviate dramatic sufferings during severe diseases.

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Impact of Altitudinal Variation on the Phytochemical Profile, Anthelmintic and Antimicrobial Activity of Two Pinus Species

Molecules ◽

10.3390/molecules26113170 ◽

2021 ◽

Vol 26 (11) ◽

pp. 3170

Author(s):

Wafaa M. Elkady ◽

Mariam H. Gonaid ◽

Miriam F. Yousif ◽

Mahmoud El-Sayed ◽

Hind A. N. Omar

Keyword(s):

Antimicrobial Activity ◽

Essential Oils ◽

Pinus Halepensis ◽

Biological Activities ◽

Anthelmintic Activity ◽

Antimicrobial Activities ◽

Pinus Pinea ◽

Active Components ◽

Pinus Species ◽

Bacteria And Fungi

Active components from natural sources are the current focus in most pharmacological research to provide new therapeutic agents for clinical use. Essential oils from the Pinus species have been traditionally used in medicine. This study aimed to investigate the chemical profile of two Pinus species, Pinus halepensis L. and Pinus pinea Mill, from different altitudes in Libya and study the effect of environmental conditions on the biological activities of essential oils. A clevenger apparatus was used to prepare the essential oils by hydrodistillation. Analyses were done using GC/MS. Anthelmintic and antimicrobial activities were tested against the earthworm Allolobophora caliginosa, gram-positive bacteria, gram-negative bacteria, and fungi. Different chemical profiles were observed among all tested essential oils, and terpenes were the most dominant class. All studied essential oils from the Pinus species exhibited a remarkable anthelmintic activity compared to the standard piperazine citrate drug. Pinus halepensis from both altitudes showed broad-spectrum antimicrobial activity against all tested microorganisms, while Pinus pinea was effective against only Escherichia coli. From these findings, one can conclude that there are variations between studied species. The essential oil compositions are affected by environmental factors, which consequently affect the anthelmintic and antimicrobial activity.

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