The fluctuations of melatonin and copeptin levels in blood serum, during surgical stress regarding the pediatric population.

2021 ◽  
Vol 17 ◽  
Author(s):  
Maria Dragoumi ◽  
Dimitrios Dragoumis ◽  
Sotirios Karatzoglou ◽  
Ioannis Spiridakis ◽  
Areti Chitoglou-Makedou ◽  
...  
Keyword(s):  
Surgical Stress ◽  
Pediatric Population ◽  
Age Groups ◽  
Underlying Disease ◽  
Diagnostic Value ◽  
The Body ◽  
Age Group ◽  
Post Surgery ◽  
Significant Difference ◽  
Group 3

Introduction: Copeptin is known to be associated with heart damage, while melatonin is a regulatory hormone associated with circadian rhythm and represents the levels of inflammation in the body. Methods and patients: The aim of the study was to measure in different surgeries the levels of copeptin and melatonin at different times before and after surgery in 56 patients aged from 5 days to 13.6 years. We measured copeptin in 50-microL serum and plasma samples from patients before surgery, immediately after surgery, and 24 hours after surgery. The measured levels are aligned with the published GC / MS data and the sensitivity of the analysis is such that serum and plasma levels can only be measured by rapid extraction. The measurement was made before surgery, immediately after surgery and 24 hours after surgery. Results: The multifactorial statistical analysis revealed a statistically significant difference between the 24-hour postoperative copeptin values in group 1 (mild-moderate gravity surgery) and group 2 (severe surgery) of the severity of the surgery. Post-hoc tests with Tukey correction for age groups in multiple comparisons of multifactorial analysis revealed a statistically significant difference (p <0.05) between 24-hour postoperative melatonin values in age group 3 (3-6 years) and 5 (6-12 years old). The age group 3 showed significantly (p <0.05) lower 24 hours postoperative melatonin values compared to the age group 5 (6-12 years). Again, these 3-6 year olds were more likely to have inflammation due to the severity of the surgery and the presence of inflammation after the surgery. Discussion: In summary, copeptin is a reliable biomarker for assessing a patient's health both preoperatively and postoperatively. Copeptin and melatonin are two independent agents and are not related to each other, and more studies will be needed with more patients of the same age and with the same underlying disease to assess their diagnostic value. Finally, melatonin could be considered an indicator of inflammation on its own and based on pre- and post-surgery values to assess a patient's health status and take appropriate actions.

scholarly journals Interaction Between Age and Change in Velocity During a Baseball Training Program

2020 ◽  
Vol 8 (6) ◽  
pp. 232596712092793
Author(s):  
Christopher Antonacci ◽  
Thomas R. Atlee ◽  
Peter N. Chalmers ◽  
Christopher Hadley ◽  
Meghan E. Bishop ◽  
...  
Keyword(s):  
Training Program ◽  
Age Groups ◽  
Maximum Velocity ◽  
Age Group ◽  
Significant Difference ◽  
Group 3 ◽  
Baseball Pitchers ◽  
Group 2 ◽  
The Relationship ◽  
Group 1

Background: Pitching velocity is one of the most important metrics used to evaluate a baseball pitcher’s effectiveness. The relationship between age and pitching velocity after a lighter ball baseball training program has not been determined. Purpose/Hypothesis: The purpose of this study was to examine the relationship between age and pitching velocity after a lighter ball baseball training program. We hypothesized that pitching velocity would significantly increase in all adolescent age groups after a lighter baseball training program, without a significant difference in magnitude of increase based on age. Study Design: Cohort study; Level of evidence, 2. Methods: Baseball pitchers aged 10 to 17 years who completed a 15-week training program focused on pitching mechanics and velocity improvement were included in this study. Pitchers were split into 3 groups based on age (group 1, 10-12 years; group 2, 13-14 years; group 3, 15-17 years), and each group trained independently. Pitch velocity was assessed at 4 time points (sessions 3, 10, 17, and 25). Mean, maximum, and mean change in pitch velocity between sessions were compared by age group. Results: A total of 32 male baseball pitchers were included in the analysis. Mean/maximum velocity increased in all 3 age groups: 3.4/4.8 mph in group 1, 5.3/5.5 mph in group 2, and 5.3/5.2 mph in group 3. While mean percentage change in pitch velocity increased in all 3 age groups (group 1, 6.5%; group 2, 8.3%; group 3, 7.6%), the magnitude of change was not significantly different among age groups. Program session number had a significant effect on mean and maximum velocity, with higher mean and maximum velocity seen at later sessions in the training program ( P = .018). There was no interaction between age and program session within either mean or maximum velocity ( P = .316 and .572, respectively). Conclusion: Age had no significant effect on the magnitude of increase in maximum or mean baseball pitch velocity during a velocity and mechanics training program in adolescent males.

Suitability of the Subaxial Cervical Laminae for Laminar Screws in the Pediatric Population: A Radiologic Anatomical Study

2021 ◽  
pp. 1-7
Author(s):  
Feyza Karagoz Guzey ◽  
Ilker Gulec ◽  
Burak Eren
Keyword(s):  
Pediatric Patients ◽  
Pediatric Population ◽  
Spinous Process ◽  
Age Groups ◽  
Anatomical Study ◽  
Age Group ◽  
Safety And Efficacy ◽  
Laminar Screw ◽  
Significant Difference ◽  
Laminar Thickness

<b><i>Introduction:</i></b> The laminar screw method was popularized during recent years. Since no data exist in the literature on its suitability for subaxial levels in the pediatric population, a radiologic anatomical study was planned to evaluate the suitability of the laminae for laminar screws in children. <b><i>Methods:</i></b> The laminar thicknesses from C3 to C7 were measured in axial sections in 120 pediatric patients using computed tomography. The patients were divided into 3 age-groups: ages 4–6, 7–9, and 10–12. Each age-group consisted of 20 boys and 20 girls. The suitability of the laminae was evaluated for 3.5-mm-thick commercially available screws and also for the 3-mm screws that could be produced in the future. If the height of the base of the spinous process is ≥ 9 mm, the segment was accepted as suitable for the bilateral screw, and ≥5 mm is for the unilateral screw. Additionally, laminar thickness and length were measured for possible short screws longer than 15 mm in the laminae that were distally thin but proximally thick. <b><i>Results:</i></b> The C4 and C5 levels had the thinnest (2.77 ± 0.6 mm and 2.81 ± 0.6 mm, respectively) and C7 had the thickest laminae (4.66 ± 0.6 mm) in all age-groups. No significant differences were found between boys and girls and right and left laminae. According to the age-groups, an increase in laminar thickness was possible by growing, but only C7 laminae thickness was statistically different between 10–12 and 4–6 age-groups (<i>p</i> &#x3c; 0.001). The last rate of the suitability was 9.1% for the 3.5-mm-thick screws and 13.75% for the 3-mm-thick screws after deletion of the bilateral insertion due to the short base of the spinous process and adding the possible short screws in the distally thin but proximally thick laminae. The rates increased with age, but the only statistically significant difference was found between 4–6- and 10–12-year-old age-groups (<i>p</i> &#x3c; 0.001). <b><i>Conclusions:</i></b> Laminar screws may be suitable for some levels of C7, C6, and C3 even in the young pediatric population. The use of thinner screws (3 mm) may increase the suitability rate. Therefore, laminar screw choice may be considered as a salvage method in pediatric patients, and all laminae may be evaluated individually for suitability. This study did not evaluate the safety and efficacy of the method in children, and these issues must be studied further.

Clinical Measurement of Maximum Mouth Opening in Children Aged 6–12

2021 ◽  
Vol 45 (3) ◽  
pp. 216-220
Author(s):  
Syed Aliya ◽  
Harsimran Kaur ◽  
Nishita Garg ◽  
Rishika ◽  
Ramakrishna Yeluri
Keyword(s):  
Age Groups ◽  
Mouth Opening ◽  
Age Group ◽  
Significance Level ◽  
Significant Difference ◽  
Group 3 ◽  
Bonferroni Test ◽  
The Mean ◽  
Group 2 ◽  
Post Hoc

Objective: To evaluate the clinical maximum mouth opening in children and its correlation with age, and sex. Study Design: Three hundred children of age 6–12 years, from different schools of Moradabad city were included. The participants were divided into three groups based on their age i.e Group 1 (n=100) 6–8 years, Group 2 (n=100) 8–10 years and Group 3 (n=100) 10–12 yrs. Three recordings of maximum mouth opening (MMO) were obtained using digital vernier caliper and the mean of three was considered as the MMO of that child. The data was analyzed using Spearman correlation, ANOVA with post- hoc Bonferroni test. The significance level was predetermined at p≤0.05 .Results: The mean MMO for children of Moradabad of aged 6–8yrs in boys is 39.87 ± 4.91 mm and in girls is 36.85± 4.09 mm. In 8–10 yeas age group, the MMO in boys is 44.5± 5.1 mm and in girls 41.77± 5.24 mm. In 10–12 year age group, the MMO in boys is 49.63± 5.56 mm and in girls is 49.33±5.32 mm respectively. The MMO was found to be higher in boys in all the three age groups. Conclusions: There was a significant difference in values of MMO in all the three age groups with boys having higher MMO values when compared to girls. Varying range of MMO values was observed within three age groups.

The influence of osteopathic correction on the rate of various rhythms of the body

2019 ◽  
pp. 64-71 ◽  
Author(s):  
A. E. Chernikova ◽  
Yu. P. Potekhina
Keyword(s):  
Heart Rate ◽  
Respiratory Rate ◽  
Age Groups ◽  
Biomechanical Properties ◽  
Dispersion Analysis ◽  
The Body ◽  
Body Tissues ◽  
Age Related ◽  
Significant Difference ◽  
Before And After

Introduction. An osteopathic examination determines the rate, the amplitude and the strength of the main rhythms (cardiac, respiratory and cranial). However, there are relatively few studies in the available literature dedicated to the influence of osteopathic correction (OC) on the characteristics of these rhythms.Goal of research — to study the influence of OC on the rate characteristics of various rhythms of the human body.Materials and methods. 88 adult osteopathic patients aged from 18 to 81 years were examined, among them 30 men and 58 women. All patients received general osteopathic examination. The rate of the cranial rhythm (RCR), respiratory rate (RR) heart rate (HR), the mobility of the nervous processes (MNP) and the connective tissue mobility (CTM) were assessed before and after the OC session.Results. Since age varied greatly in the examined group, a correlation analysis of age-related changes of the assessed rhythms was carried out. Only the CTM correlated with age (r=–0,28; p<0,05) in a statistically significant way. The rank dispersion analysis of Kruskal–Wallis also showed statistically significant difference in this indicator in different age groups (p=0,043). With the increase of years, the CTM decreases gradually. After the OC, the CTM, increased in a statistically significant way (p<0,0001). The RCR varied from 5 to 12 cycles/min in the examined group, which corresponded to the norm. After the OC, the RCR has increased in a statistically significant way (p<0,0001), the MNP has also increased (p<0,0001). The initial heart rate in the subjects varied from 56 to 94 beats/min, and in 15 % it exceeded the norm. After the OC the heart rate corresponded to the norm in all patients. The heart rate and the respiratory rate significantly decreased after the OC (р<0,0001).Conclusion. The described biorhythm changes after the OC session may be indicative of the improvement of the nervous regulation, of the normalization of the autonomic balance, of the improvement of the biomechanical properties of body tissues and of the increase of their mobility. The assessed parameters can be measured quickly without any additional equipment and can be used in order to study the results of the OC.

scholarly journals Secular Trends of Underweight, Overweight, and Obesity in Children and Adolescents from Ukraine

2021 ◽  
Vol 18 (6) ◽  
pp. 3302
Author(s):  
Katarzyna Dereń ◽  
Justyna Wyszyńska ◽  
Serhiy Nyankovskyy ◽  
Olena Nyankovska ◽  
Marta Yatsula ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Age Groups ◽  
Overweight And Obesity ◽  
The Body ◽  
World Health ◽  
Public Health Issue ◽  
Significant Difference ◽  
Significant Public Health ◽  
Health Organization ◽  
Obesity In Children

Overweight and obesity, as well as underweight in children and adolescents, pose a significant public health issue. This study aimed to investigate the secular trend of the incidence of underweight, overweight, and obesity in children from Ukraine in 2013/2014 and 2018/2019. The studies were conducted in randomly selected primary and secondary schools in Ukraine. In total, 13,447 children (6468 boys and 6979 girls) participated in the study in 2013/2014 and 18,144 children (8717 boys and 9427 girls) participated in 2018/2019. Measurements of body weight and height were performed in triplicate. Underweight, overweight, and obesity were diagnosed according to the standards of the World Health Organization (WHO). In the group of girls, a significant difference between 2013/2014 and 2018/2019 measurements was found only among 7-year-olds. The percentage of girls at this age exceeding the body mass index (BMI) norm was lower in the 2018/2019 study. In boys, a significant difference was also found in 7-year-olds, and, as in girls, a lower share of overweight and obesity was found in 2018/2019. But for the ages of 12, 13, and 15, the significant differences had a different character—more overweight or obese boys were found in the 2018/2019 study. The proportion of underweight children was similar for the majority of age groups in both genders and did not differ in a statistically significant way.

scholarly journals National Surveillance of Injury in the Republic of Korea: Increased Injury Vulnerability in the Late Middle Age

2021 ◽  
Vol 18 (3) ◽  
pp. 1210
Author(s):  
Hansol Chang ◽  
Ji Young Min ◽  
Dajeong Yoo ◽  
Se Uk Lee ◽  
Sung Yeon Hwang ◽  
...  
Keyword(s):  
Middle Age ◽  
Age Groups ◽  
Admission Rate ◽  
Age Group ◽  
National Surveillance ◽  
Early Prevention ◽  
Group 4 ◽  
Group 3 ◽  
Prevention Methods ◽  
Injury Outcomes

Surveillance of injury patterns and comparisons among different age groups help develop a better understanding of recent injury trends and early prevention. This study conducted a national surveillance of injury by age group. Data were collected retrospectively from Emergency Department-Based Injury In-Depth Surveillance (EDIIS) in South Korea, between January 2011 and December 2017. Patients were divided into the following four groups by age: Group 1–18 to 34 years, Group 2–35 to 49 years, Group 3–50 to 64 years, and Group 4—≥65 years. A total of 1,221,746 patients were included in the study. Findings revealed that, each year, the injury rate increased in the population aged ≥65 years. The place and mechanism of injury in Group 3 were similar to those in younger age groups, while injury outcomes and injured body parts were similar to those in Group 4. Further, hospital admission rate, ICU admission rate, hospital death, traumatic brain injury, and injury severity increased with an increase in age. In our study, each age group showed diverse characteristics pertaining to the mechanism, place, time, and outcomes of injuries. Interestingly, Group 3, which represented the late middle age, exhibited increased vulnerability to injury, and emerged as a gray zone between the young and old age groups. Therefore, different injury prevention methods are needed for each age group. Specifically, early prevention methods need to be implemented from the late middle age to improve the old age group’s injury outcomes.

scholarly journals The Accuracy of Broselow Tape Weight Estimate among Pediatric Population

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Turki M. AlHarbi ◽  
Abdullaziz AlGarni ◽  
Fasial AlGamdi ◽  
Mona Jawish ◽  
Tariq Ahmad Wani ◽  
...  
Keyword(s):  
Body Weight ◽  
Pediatric Population ◽  
Body Height ◽  
Age Groups ◽  
Cross Sectional Study ◽  
The Body ◽  
Accurate Estimation ◽  
Cross Sectional ◽  
Actual Weight ◽  
Medical City

Objective.To determine the accuracy of the Broselow Tape (BT) versions 2007 and 2011 in estimating weight among pediatric population.Methods.A cross-sectional study was conducted at King Fahad Medical City and six schools across Riyadh province on 1–143-month-old children. BT 2007 and 2011 estimated weights were recorded. Both tapes via the child’s height produce an estimated weight, which was compared with the actual weight.Results.A total of 3537 children were recruited. The height (cm) of the subjects was97.7±24.1and the actual weight (kg) was16.07±8.9, whereas the estimated weight determined by BT 2007 was15.87±7.56and by BT 2011 was16.38±7.95. Across all the five age groups, correlation between actual weight and BT 2007 ranged between 0.702 and 0.788, while correlation between actual weight and BT 2011 ranged between 0.698 and 0.788. Correlation between BT 2007 and BT 2011 across all the five age groups ranged from 0.979 to 0.989. Accuracy of both the tape versions was adversely affected when age was >95 months and body weight was >26 kilograms.Conclusions.Our study showed that BT 2007 and 2011 provided accurate estimation of the body weight based on measured body height. However, 2011 version provided more precise estimate for weight.

scholarly journals The Effect of Exercise on the Total Leukocyte, Absolute Neutrophil, Lymphocyte and Platelet Counts among Sudanese Football Players

2021 ◽  
Vol 11 (6-S) ◽  
pp. 26-32
Author(s):  
Nihad Elsadig Babiker ◽  
Raheeg Mubark Anwer
Keyword(s):  
Physiological Stress ◽  
Hematological Parameters ◽  
Venous Blood ◽  
Age Groups ◽  
The Body ◽  
Case Group ◽  
Football Players ◽  
Platelet Counts ◽  
Significant Difference ◽  
Age Variation

Background: Aerobic exercise induces physiological stress on the body and brings changes in hematological parameters. This study aimed to determine the effect of playing football as an exercise on the total white blood cell count, absolute Neutrophil, lymphocyte and Platelet counts among Sudanese football players. Material and method:  This was a descriptive case control study, done on a number of football players in Khartoum state, Sudan and conducted within the period from August 2021 to October 2021. Three ml of venous blood samples had been collected from every participant in the study, parameters had been measured and calculated using blood cells counter (Sysmex KX-21N).                                                           Results: When compared the TWBCs, Absolute Neutrophil, Lymphocytes and platelet counts between cases and control there was a significant differences with (P ≤0.05). Also there was a significant difference in the case group before and after one hour of exercise with (P =0.00), and in significant differences between different age groups with (P ≥0.05). Conclusion: Playing football for 1 hour cause a significant increase in the TWBCs, absolute Neutrophils, absolute Lymphocytes and Platelets counts. Age variation has no effect on the measured parameters Keywords: Football, TWBCs, Neutrophils, Lymphocytes and Platelets.

scholarly journals The burden of the current curative expenditure of injury in Dalian, China-A study based on “System of Health Accounts 2011”

2020 ◽  
Author(s):  
Shu Sun ◽  
Liuna Yang ◽  
Xinzhu Hu ◽  
Yalan Zhu ◽  
Boxi Liu ◽  
...  
Keyword(s):  
Foreign Body ◽  
Lower Limb ◽  
Control Strategies ◽  
Age Groups ◽  
The Body ◽  
Age Group ◽  
Curative Care ◽  
Health Accounts ◽  
System Of Health Accounts ◽  
The Cost

Abstract Background Injury is one of the major public health problems, which causes more than 5 million deaths in the world every year. Cases of specific types of injury put a tremendous threat to human health and also add a heavy medical burden on individuals and societies. This study was to calculate and analyze the current curative expenditure (CCE) of injury in Dalian and consequently to provide control strategies for decision-makers. Main text: A total of 565 medical institutions were selected with multistage stratified cluster random sampling, containing 4,375,351 valid samples. Subsequently, the distribution of injury CCE in different dimensions (including age and site of injury) was analyzed under the framework of System of Health Accounts 2011(SHA 2011) using the established database. There were increases from 32.36/100,000 in 2006 to 37.34/100,000 in 2017 and from 46.12/100,000 in 2006 to 54.48/100,000 in 2017 in urban and rural residents respectively. The study found that the CCE of injury in Dalian had reached 1572.73 million RMB, accounting for 7.45% of the total curative care expenditure. In the 15–25 age group, the cost of injury accounts for a larger proportion of CCE than other age groups. Among the injuries in different regions of the body, injuries to the spine, lower limb, head and foreign body entering cost the most. Conclusions Dalian has a relatively serious burden of injury costs. The essential and primary goal is to reduce the cost and increase the benefit of attending to patients with injuries. Specific control strategies should be tilted toward the age group 15–25. Injuries to the spine, lower limb, head and foreign body entering also should be priorities of interventions.

scholarly journals ULTRASOUND;

2012 ◽  
Vol 19 (02) ◽  
pp. 187-192
Author(s):  
EJAZ HUSSAIN SIDDIQUI ◽  
SAAD SIDDIQUI ◽  
NOREEN SHAH
Keyword(s):  
Pediatric Population ◽  
Adult Population ◽  
Age Groups ◽  
X Rays ◽  
Geriatric Population ◽  
Cross Sectional ◽  
Study Results ◽  
Significant Difference ◽  
Ultrasound Findings ◽  
Hepatobiliary Diseases

Objectives: To assess common presenting features and the role of Ultrasound in evaluation of Hepatobiliary diseases in ourpopulation. Design: Cross sectional study. Setting: Khyber X rays, Khyber Medical Centre, Peshawar. Period: August 2010 to December2010. Material and Methods: Data from patients presenting for evaluation of Hepatobiliary diseases was analyzed for presenting complaintsand ultrasound findings according to objectives of the study. Results: In total 197 cases were included in the study. The age wise categorizationincluded pediatric population (6.1%) adult population (87.3%) and geriatric population (6.6%). Upper abdominal pain was the most commonpresenting feature in all age groups as well as in both genders. Cholelithiasis with or without cholecystitis was the most common ultrasoundfinding in all age groups. No statistically significant difference was found between presenting features or ultrasound findings in different agegroups as well as across gender. Conclusions: Hepatobiliary diseases are among major illnesses in our region. Ultrasound is a sensitive anduseful tool for screening and evaluation of Hepatobiliary disorders.

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