Clinical Evaluation of Febrile Thrombocytopenia in Western Rajasthan - a Hospital-based Study

2020 ◽  
Vol 20 (5) ◽  
pp. 718-723
Author(s):  
Sahadev Choudhary ◽  
Deepak Kumar ◽  
Gopal K. Bohra ◽  
Alok Gupta ◽  
Durga S. Meena ◽  
...  
Keyword(s):  
Dengue Fever ◽  
Clinical Evaluation ◽  
Liver Dysfunction ◽  
Febrile Illness ◽  
Common Symptom ◽  
Number Of Patients ◽  
Common Causes ◽  
Common Etiology ◽  
Bleeding Manifestation ◽  
The Common

: A number of patients of febrile thrombocytopenia increase during monsoon and postmonsoon period. Diseases like dengue fever, malaria, chikungunya fever, etc. are responsible for the clustering of febrile thrombocytopenia cases during this period. The diagnosis of fever with thrombocytopenia cases can be challenging and physicians should be aware of the regional and endemic seasonal cause of this syndrome. Study Design: It is a prospective observational study. Material and Methods: The study included 103 consecutive patients. The patients admitted with acute febrile illness defined by a duration of less than 2 weeks with thrombocytopenia were evaluated. Results: The present study included 103 consecutive cases of febrile thrombocytopenia. Out of these, 71.84% were male and 28.16% were female. The most common etiology for febrile thrombocytopenia was dengue fever (44.66%) and malaria (31.06%). Among clinical evaluation of the cases, fever was the inclusion criteria. Myalgia was the most common symptom found after fever, which was observed in 83.5% of the patients. The most common bleeding manifestation was petechiae/ purpura (12.62%) followed by hematuria (6.80%). Renal dysfunction was present in all 8(100%) cases of sepsis, followed by 14(43.75%) cases of malaria. All sepsis cases also had liver dysfunction, followed by 91.3% cases in dengue fever and 90.62 % cases in malaria had liver dysfunction. Conclusion: The study showed that acute febrile thrombocytopenia is an important seasonal syndrome. The common causes are dengue fever and malaria. Early identification of these diseases and prompt treatment decreases complications and reduces mortality.

scholarly journals A study of dengue and hepatopathy

2017 ◽  
Vol 5 (6) ◽  
pp. 2625
Author(s):  
Surendra Kumar ◽  
Rajkumar Lakhiwal ◽  
Vinod Aswal ◽  
Suresh Gajraj ◽  
Ishan Patel ◽  
...  
Keyword(s):  
Dengue Fever ◽  
Liver Dysfunction ◽  
Complete Blood Count ◽  
Early Recognition ◽  
Severe Disease ◽  
Health Concern ◽  
Bleeding Tendency ◽  
Function Tests ◽  
Number Of Patients ◽  
Body Ache

Background: Dengue is a major international health concern that is prevalent in tropical and sub-tropical countries. It is 2nd most common arthropod borne disease in India. There are certain clinical features that are associated with Dengue in addition of the classical features. Previously organ impairment has been only considered under set up of severe disease. On the recent years, several studies have suggested the possibility of early involvement of the liver in dengue. Further due to its atypical presentation often dengue missed out as a differential diagnosis.Methods: A total of 50 patients were selected to be a part of study after applying inclusion and exclusion criteria. Only those patients were included in the study who had classical features of dengue- fever with chills, body ache, headache, rash, bleeding manifestations and thrombocytopenia and had a positive ELISA test i.e. IgM antibodies against dengue virus. Patients who had malaria and enteric fever were excluded from the study. All patients were subjected to a detailed history and a thorough clinical examination. A complete blood count, liver function tests, renal function tests, chest X-ray and USG abdomen were also done.Results: An analysis of 50 patients suffering from dengue showed liver dysfunction was present in all patients. Vomiting was an important symptom present upto 70% of patients. SGOT levels were higher than SGPT levels. Hepatosplenomegaly and ascitis were also present in significant number of patients. An analysis of these patients revealed that patients typically demonstrate high grade fever, body ache, rash, thrombocytopenia and bleeding tendency, there were other features such as liver dysfunction including a preferential rise of SGOT, hepatosplenomegaly, ascitis, pleural effusion and leucopoenia.Conclusions: This study showed that dengue fever was seen in the third decade and that AST and ALT levels were raised in the majority of these patients. It was also found that AST levels were more than ALT levels. So, AST and ALT can be a useful early marker to assess the severity of the disease which can thus lead to early recognition of high risk cases. The presence of raised liver enzymes in all patients, ascitis, hepatosplenomegaly, elevation of SGOT more than SGPT, should be kept in mind when evaluating patients with suspected dengue.

scholarly journals Dengue and Scrub Typhus Coinfection in a Patient Presenting with Febrile Illness

2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Surendra Sapkota ◽  
Sudeep Bhandari ◽  
Subash Sapkota ◽  
Rabin Hamal
Keyword(s):  
Dengue Fever ◽  
Scrub Typhus ◽  
Febrile Illness ◽  
Acute Febrile Illness ◽  
Laboratory Parameters ◽  
Vector Borne Diseases ◽  
Common Causes ◽  
Vector Borne ◽  
High Degree ◽  
Timely Treatment

Dengue fever and scrub typhus are common causes of acute febrile illness of unclear origin in Asia. Though coinfections of many vector-borne diseases have been described, articles on dengue and scrub typhus coinfection are distinctly limited. In case of coinfection with dengue and scrub typhus, vigilant monitoring of vitals, platelets transfusion, and timely treatment with doxycycline are necessary. High degree of suspicion has to be made for coinfection in a patient presenting with febrile illness with thrombocytopenia and deranged laboratory parameters in postmonsoon season in endemic regions in Asia.

scholarly journals Clinical study of central serous chorioretinopathy presenting in a tertiary care centre

2019 ◽  
Vol 7 (11) ◽  
pp. 4200
Author(s):  
Ramamani Dalai ◽  
Rajashree Rout ◽  
Manjula Pradhan ◽  
Prasanta Kumar Nanda
Keyword(s):  
Central Serous Chorioretinopathy ◽  
Tertiary Care ◽  
Population Based ◽  
Tertiary Care Centre ◽  
Population Based Study ◽  
Medical College ◽  
Number Of Patients ◽  
Department Of Ophthalmology ◽  
Common Causes ◽  
The Common

Background: Central Serous chorioretinopathy (CSCR) is one of the common causes of visual handicap affecting young people of highly intellectual professionals at the peak of their career which can lead to irrecoverable loss of vision.Methods: The present prospective observational population-based study was conducted in the Department of Ophthalmology, S.C.B. Medical College, Cuttack, Odisha from October 2013 to September 2015. The total number of patients attended the Outpatient Department (OPD) during the study period were 1,83,199. Amongst which 123 patients diagnosed to have CSCR were selected for the present study.Results: Incidence of CSCR during in this study period was 0.06%. The age group most commonly affected was 31 to 40 years. Males were affected 7 times more commonly than females. Increased incidence was noticed in bank employees (21.1 %) and IT professionals (17.8%).Conclusions: There was increased incidence of the disease in people under stressful life condition.

scholarly journals Causes of Hoarseness of Voice Based on Fiber Optic Laryngoscopy (FOL): Our Experiences in ENT OPD of a Peripheral Military Hospital

2021 ◽  
Vol 33 (1) ◽  
pp. 34-37
Author(s):  
Mohammad Misbah Al Kabir Sumon ◽  
Abu Hasanat Md Habibur Rahman ◽  
Sultana Dil Afsana ◽  
Md Belal Hossain
Keyword(s):  
Fiber Optic ◽  
Vocal Cord Palsy ◽  
Military Hospital ◽  
Common Symptom ◽  
Basic Tool ◽  
Vocal Polyp ◽  
Common Causes ◽  
Chronic Laryngitis ◽  
The Common ◽  
Medicine Today

Introduction: This study was aimed to determine the common causes of hoarseness of voice in ENT OPD of a military hospital. Materials and Methods: This was an observational study carried out on 93 patients presented with hoarseness of voice in ENT OPD CMH Momenshahi, a peripheral military hospital, for a period of 2 years, from 1st April 2017 to 30th April 2019. Only Fiber Optic Laryngoscopy (FOL) findings were evaluated to diagnose the causes of hoarseness. Data were obtained from FOL findings documentation register. All data were analyzed using IBM SPSS version 25.0. Patients consent was taken. Results: Total 93 cases were studied irrespective of age and sex. Among them 34 (36.60%) were males and 59 (63.40%) were females. Commonly affected age group was 21-30 years. With a mean age of 33.34 years. Majority of the cases were housewife 44 (44.10%). The most common cause of hoarseness was Chronic Laryngitis 25 (26.9%). The other causes were vocal polyp 17 (18.30%), VC nodule 13 (14%), Incomplete Glottal closure 14 (18.30%), leukoplakia of VC 5 (5.40%) and Vocal cord palsy 3 (3.20%). Normal findings were found in 11 (11.80%) cases. Conclusion: Hoarseness is a common symptom of laryngeal dysfunction. Military personnel are frequently affected like general population. Common causes are almost same with a very few variations. FOL should be the basic tool to diagnose the causes of hoarseness. Medicine Today 2021 Vol.33(1): 34-37

scholarly journals A study of etiology, clinical profile and outcome in children aged 1-12 years presenting with fever of 1-3 weeks duration in a tertiary hospital

2019 ◽  
Vol 6 (2) ◽  
pp. 569
Author(s):  
Kavitha Devarajulu ◽  
Prabu Velusamy
Keyword(s):  
Tract Infection ◽  
Tertiary Care ◽  
Febrile Illness ◽  
Signs And Symptoms ◽  
Tertiary Hospital ◽  
Connective Tissue Disorder ◽  
Cns Infection ◽  
Common Symptom ◽  
Different Types ◽  
The Common

Background: The objective of the study was to find out the etiology, associated signs and symptoms of fever of 1-3 weeks in the age group of 1-12 years and their outcome following treatment in a tertiary care hospital.Methods: This was an observational prospective study conducted at Institute of child health and hospital for children, Egmore, Chennai during the period from January 2011 to October 2012. A total of 621 children aged 1-12 years with 1-3 weeks of fever were included in the study. Demographic, clinical and diagnostic data were collected and analyzed for each patient and outcome was assessed for different types of febrile illness.Results: Out of 621 patients enrolled in the study, enteric fever was diagnosed in majority cases followed by respiratory tract infection, urinary  tract  infection  in  102  (16.4%), leptospirosis in 78 (12.6%), malaria in 60(9.7%), dengue fever in 8 (7.7%) rickettsia infection in 36 (5.8%), tuberculosis in 24 (3.9%), CNS infection in 18 (2.9%), viral hepatitis in12 (1.9%), malignancy in 5(0.8%), connective tissue disorder in 4 (0.6%), localized infection in 2 (0.3%) cases. The incidence was unknown in 10 patients (1.6%). Fever and vomiting were the common symptom seen in all the patients. Mortality was observed 18 (2.94%) cases.Conclusions: The similarity of illness and complexity in etiological conditions demonstrates the complications of diagnosis and treatment of fevers. The present study findings provided rationale information for development of guidelines necessary for treatment and thereby reducing the mortality rate in children of age 1-12 years with incidence of febrile illness.

scholarly journals Chronic Cough in Thymoma

2010 ◽  
Vol 49 (178) ◽  
Author(s):  
K K Agrawal ◽  
SS Dhakal ◽  
N Bhatta ◽  
B Pradhan ◽  
RK Chaurasia ◽  
...  
Keyword(s):  
Primary Care ◽  
Chronic Cough ◽  
Primary Care Physicians ◽  
Symptomatic Treatment ◽  
Anterior Mediastinum ◽  
Medical Attention ◽  
Common Symptom ◽  
Common Causes ◽  
The Common ◽  
Lung Infections

Cough is one of the most common symptom for which patients seek medical attention from primary care physicians and pulmonologists. Although tuberculosis and other lung infections are common throughout the developing world, they are not among the most common causes of chronic cough. We report a case of a 23 years old male who presenting to the outpatient clinic with chronic cough not responding to regular and symptomatic treatment that was diagnosed to have thymoma. After all the common causes for chronic cough have been ruled out, unusual causes should also be considered in the differential diagnosis. KEYWORDS: Chronic cough, Thymoma, Anterior Mediastinum.

scholarly journals Variability of Presentations and CT-Scan Findings in Children with Neurocysticercosis

2012 ◽  
Vol 9 (2) ◽  
pp. 17-21 ◽  
Author(s):  
E Gauchan ◽  
T Malla ◽  
S Basnet ◽  
K S Rao
Keyword(s):  
First Episode ◽  
Parietal Region ◽  
Significant Morbidity ◽  
Number Of Patients ◽  
Common Causes ◽  
The Common ◽  
Psychiatric Manifestations ◽  
The Brain ◽  
Afebrile Seizure

Background Neurocysticercosis is one of the common neurological morbidities in childhood. Objectives To find the commonest mode of presentation of this disorder in children. The study also aims to find out the age at which it commonly occurs, commonest site affected in the brain and the ethnic group and region most commonly affected in Western Nepal. Methods Retrospective hospital based study carried out in the Department of Pediatrics, Manipal Teaching Hospital, Pokhara from June 2004 to June 2009. Results Over the period of five years, 678 patients were admitted for seizures; out of which 109 patients were diagnosed as having neurocysticercosis (16%). Out of them, 66 (60.5%) were males and 43 (39.4%) were females. The age of presentation varied from 18 months to 16 years, with mean age 9.77 years. The most common age of presentation was between 6-10 years (n=47; 43.1%) and 11-15 years (n=47; 43.1%).Maximum number of patients were from Kaski district (n=41; 37.6%) followed by Syangja (n=34; 31.1%).The commonest presentation was with seizures (n=85; 77.9 %); generalised seizures was present in 45 patients (52%). Psychiatric manifestations were present in 3 patients (2.7%). The lesions were found mostly in the parietal region (n=65; 59.6 %). Most of the lesions were single (n=89; 81.6%). Out of 109 patients, 74 patients (67.8%) improved without any recurrence of symptoms on two years follow-up. ConclusionNeurocysticercosis is a preventable zoonotic disease which results in significant morbidity in children where sanitary measures are inadequate. Any child presenting with a first episode, afebrile seizure should be screened for neurocysticercosis provided other common causes are ruled out.DOI: http://dx.doi.org/10.3126/kumj.v9i2.6281 Kathmandu Univ Med J 2011;9(2):17-21 

Common causes and treatment of hypoglycemia in older patients with diabetes at Thanh Nhan hospital

2021 ◽  
Vol 25 (2) ◽  
pp. 76-85
Author(s):  
Trung Anh Nguyen ◽  
Thi Thu Huong Nguyen ◽  
Thi Thanh Huyen Vu
Keyword(s):  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Insulin Regimen ◽  
Cross Sectional ◽  
Common Cause ◽  
Glucose Injection ◽  
Number Of Patients ◽  
Common Causes ◽  
Patients With Diabetes ◽  
The Common

Objectives: To determine common causes and treatment of hypoglycemia in oler patients with diabetes at Thanh Nhan hospital. Methods: A cross-sectional study on 1215 diabetic patients treated at Thanh Nhan Hospital from November 2018 to May 2019. Subjects were interviewed according to a uniform medical record. Hypoglycemia was diagnosed according to the ADA 2018 criteria: blood glucose ≤ 3.9 mmol/l. Results: the most common cause of hypoglycemia was a reduced diet (49.6%); eating late (24.1%); skipping meals (9.3%); overdose, wrong insulin regimen due to patients (7.4%); overdose and wrong insulin regimen by doctor (4.2%). The proportion of patients receiving intravenous hypertonic glucose injection/infusion was 7.7%; eating foods containing glucose was 63.1%; eating foods containing carbonhydrat was 29.2%. The majority of patients with symptoms of hypoglycemia lasting within 15 minutes accounted for 56.3%, the number of patients with hypoglycemia lasting more than 60 minutes accounted for 0.9%. Conclusions: The common cause of hypoglycemia in the study subjects was mainly related to the patient's diet. The treatment of the patient's hypoglycemia was not completely correct. Therefore, medical staff should have measures to advise and educate about the causes as well as how to manage hypoglycemia for this subject regularly

scholarly journals Dengue Fever and its Dermatological Changes

2020 ◽  
Vol 3 (1) ◽  
pp. 11-14
Author(s):  
Mohan Kumar R ◽  
Muddu Surendra Nehru
Keyword(s):  
Dengue Fever ◽  
Clinical Features ◽  
Skin Rash ◽  
Dengue Infection ◽  
Clinical Manifestations ◽  
General Medicine ◽  
Febrile Illness ◽  
Medical Sciences ◽  
Trial Analysis ◽  
Common Causes

Background: Around the world dengue incidence has dramatically grown with a large number of asymptomatic cases. Worldwide about 390 million dengue infections were occurring per year, among them 96 million people were developing clinical manifestations with varied severity. About 3.9 billion people residing in 128 countries, were at-risk of dengue virus infection. Dengue fever (DF) is one of the common causes of acute febrile illness. In half the patients with dengue fever skin involvement occurs. Aim & Objectives: To study the socio-demographic parameters, clinical features and laboratory parameters among the patients with and without skin rash in dengue infection. Also determine outcome among the patients with dengue fever and its association with skin rash. Subjects and Methods: A hospital-based, analytical prospective study was conducted in the Department of General Medicine, Sapthagiri Institute of Medical Sciences and Research Center, Bangalore. Patients older than 16 years of age with clinical features and laboratory reports suggestive of dengue infection were included. The study was conducted for a period of 12 months from 1st December 2014 to 30th November 2015. These patients were further divided based on the skin rash presence and absence. The data obtained was entered in Microsoft Excel and analyzed in SPSS version-22 trial. Analysis was done using unpaired students t-test, ANOVA. Results: In total 97 patients with dengue fever were enrolled into the study. About 14.4 p.c (14) patients were with skin rash. The patients with skin rash were found to have lower platelet levels during the disease course. Patients with skin rash had higher percentage of platelet transfusion which was statistically significant. Conclusion: A cutaneous involvement may facilitate clinical diagnosis but it may not be present among all the patients.

The Utility of Non-invasive Tests for Detection of Previous Proximal-vein Thrombosis

1995 ◽  
Vol 73 (04) ◽  
pp. 592-596 ◽  
Author(s):  
Sabina Villalta ◽  
Paolo Prandoni ◽  
Alberto Cogo ◽  
Paola Bagatella ◽  
Andrea Piccioli ◽  
...  
Keyword(s):  
Clinical Evaluation ◽  
Femoral Vein ◽  
Clinical Score ◽  
Diagnostic Methods ◽  
Popliteal Vein ◽  
Venous Reflux ◽  
Study Objective ◽  
Vein Thrombosis ◽  
Non Invasive ◽  
The Common

SummaryBackground. Despite the availability of several diagnostic methods for the detection of deep-vein thrombosis (DVT), the identification of previous episodes of DVT remains a diagnostic challenge.Study objective. To assess the reliability of a combination of a standardized clinical score with three non-invasive tests: compression ultrasonography (CUS), Doppler ultrasound (DUS), and photoplethysmography (PPG), in determining the presence or the absence of previous proximal DVT.Methods. One hundred consecutive unselected outpatients were identified, who had undergone contrast venography six to nine years previously because of the clinical suspicion of DVT (confirmed in 43). They were blindly reinvestigated by a panel of trained operators unaware of venography results. They underwent a clinical evaluation of the lower limb, by applying a standardized score to five symptoms and six signs (grading each item from 0 to 3); a PPG test to determine the venous refilling time; a DUS test to determine the venous reflux separately in the common femoral and the popliteal vein; and a CUS test to determine vein compressibility in the same regions.Results. An abnormal CUS test and/or the demonstration of venous reflux in the popliteal region and/or a high clinical score (≥ 8) identified twenty-four of the 43 (56%) DVT + patients with a specificity of 89%. The combination of normal CUS with the absence of venous reflux in both the common femoral and popliteal vein and a low clinical score excluded previous thrombosis in 45 (79%) of the 57 DVT- patients (negative predictive value, 78%). Abnormal venous reflux in the isolated common femoral vein did not reliably predict the presence or absence of previous DVT. However, this occurred in only 13 (13%) patients. The PPG determination of venous refilling time did not improve the results obtained with the other tests.Conclusions. The combination of a standardized clinical evaluation with the results of CUS and DUS can reliably diagnose or exclude previous proximal-vein thrombosis in almost 90% of patients with previous episodes of suspected DVT.

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