Clinical and etiological evaluation of secondary seizures by computed tomography and electroencephalogram

2016 ◽  
Vol 5 (10) ◽  
pp. 4982
Author(s):  
Archana Aher* ◽  
Satish Gore

This study was conducted to determine the clinical evaluation and various etiological factors of secondary seizures in patients admitted to Government Medical College, Nagpur. We evaluated 58 patients of secondary seizures from Dec 2011 to Oct 2013. Secondary seizures were defined as case of seizure with CT (brain) or MRI (brain) abnormality1. Out of 58 cases 35 were males and 23 were females. Mean age of study subjects was 34.85. The commonest presenting feature was generalized tonic clonic convulsions (42 patients) followed by focal seizures (16 patients).  Todd’s palsy was observed in 4 cases. Aura was present in 24 cases. According to CT brain scan the aetiology was – neurocysticercosis (34.48%), post stroke (27.59%), tuberculoma (24.14%). Space occupying lesions(SOLs) were present in 8 patients, out of whom 4 had brain tumour, 2 patients had brain abscess, 1 had hydatid cyst and 1 had metastasis. Majority of lesions were located in frontal region (58.62%), followed by in parietal region (44.83%), in temporal region (25.86%) and in occipital region (13.79 % patients). In our study neurocysticercosis was found to be the commonest cause of secondary seizures. As in a meta-analysis it was found that cysticidal drugs result in better outcome in patients of neurocysticecosis, we recommend that the patients of secondary seizures should be identified for the aetiology and treated at the earliest2.

Author(s):  
Sharmistha Sarkar ◽  
Dhruba Prasad Paul ◽  
Jayanta Ray

Background: Adverse maternal and perinatal outcomes are related to pregnancies spaced too closely together. Objective of present study was to compare the expulsion rate and complications between post placental IUCD insertion between caesarean section and vaginal delivery.Methods: This study was a prospective comparative study conducted in the department of Obstetrics and Gynecology, at Agartala Government Medical College over 1.5 Years (January 2016-June2017) All cases at term pregnancy delivering by caesarean section and vaginal delivery were divided into two different groups. Sample size of 105 in each group. Subjects recruited from-obstetrics OPD and casualty of Agartala Government Medical College (AGMC) and GB Pant Hospital expulsion rate and complications. Comparative evaluation of Expulsion rate and complications following post placental IUCD insertion between caesarean section and vaginal delivery at the end of six months, one year and one and half year.Results: There was no significant difference in either complications between the two groups (P value-.913) or outcomes (p value-.035). Expulsion rate 18.2% following vaginal delivery compared to those with intracaesarean insertion i.e 3.8%.Conclusions: The complications associated with postplacental Intrauterine device insertion is insignificant, still the awareness, acceptance and continuation are very low. Therefore Information, education Communication activity by the field workers must be enhanced to overcome this knowledge gap.


2009 ◽  
Author(s):  
Li Zhang ◽  
Qing Xu ◽  
Chong Chen ◽  
Carol L. Novak

2021 ◽  
pp. 17-21
Author(s):  
Debraj Saha ◽  
Aarti Anand ◽  
Jawahar Rathod ◽  
Prajwaleet Gour ◽  
Shivprasad Jaybhay ◽  
...  

Objective: To investigate the incidence and spectrum of neuroimaging ndings and their prognostic role in hospitalized COVID-19 patients in Government Medical College Nagpur along with their correlation with D-Dimer Values and GCS . Methods: This is a retrospective cohort study of 774 COVID-19 conrmed patients admitted to Government Medical College st st Nagpur between 1 April 2020 and 31 October 2020. Clinical data were extracted from electronic medical records, and particularly data of all neurological symptoms were extracted from the imaging reports. Four neuro-radiologists evaluated all neuroimaging studies for acute neuroimaging ndings related to COVID-19. Plasma D-dimer levels were measured using a particle-enhanced, immunoturbidimetric assay on admission in the 116 patients who came for evaluation of neurological symptoms. Moreover ,the patients were classied into different groups as mild, moderate and severe based on their GCS scores and was assessed with respect to their neuro-imaging ndings. Results: 15 % of the admitted patients suffered from neurological symptoms. Acute stroke was the most common nding in the patients with positive neuroimaging ndings resulting in 34.4% of the patients with positive neuroimaging ndings. Other ndings were subacute infarcts (13.8%), Chronic lacunar infarcts (20.6%) , Intraparenchymal hemorrhage in 10.4 %, hypertensive encephalopathy in 7 % and subarachanoid hemorrhage in 3.4 %. Plasma median D-dimer levels were signicantly (P฀ =฀ 0.000) higher in Acute stroke patients as compared to COVID 19 positive patients who had negative CT scan imaging features(0.88; interquartile range [IQR], 0.28–2.11 mg/L and 0.31; IQR, 0.17–0.74 mg/L). Patients who have positive neuroimaging ndings presented with a lower GCS whereas patients who had negative neuroimaging ndings presented with a higher GCS. Conclusions: Our study demonstrates acute stroke is the most common neuroloimaging nding in hospitalized COVID 19 Patients. Moreover D-Dimer values are highly predictive of acute ischemic stroke. Patients with positive neuro-imaging ndings have poor GCS scores.


PEDIATRICS ◽  
1979 ◽  
Vol 64 (2) ◽  
pp. 233-237
Author(s):  
K. S. Krishnamoorthy ◽  
D. C. Shannon ◽  
G. R. DeLong ◽  
I. D. Todres ◽  
K. R. Davis

We report our experience with the neurologic sequelae (at a mean follow-up of 24 months) among the 15 surviving infants who have had neonatal intraventricular hemorrhage (IVH) documented by computerized tomographic (CT) brain scan. Neurologically six infants (40%) are normal, six infants (40%) mildly impaired, and three infants (20%) moderate to severely impaired. The neurologic outcome correlated to the degree of hemorrhage seen in the CT scans when IVH was classified into four grades. None of the other neonatal factors examined showed significant correlation with the outcome.


2021 ◽  
Vol 10 (27) ◽  
pp. 2001-2006
Author(s):  
John Britto Augustin ◽  
Sureshbaboo Variamkandi

BACKGROUND Corneal ulcer is the leading cause of ocular morbidity and monocular blindness worldwide. To effectively prevent blindness in patients with corneal ulcer, a proper understanding of the risk factors predisposing to ulceration, its clinical and microbiological characteristics are essential. Timely identification of aetiological agents causing corneal ulcers and their prompt treatment helps to save the vision. We wanted to detect aetiological agents of corneal ulcer with special references to fungal causes and characterize the fungal aetiological agents to species level. METHODS This is a cross sectional study, conducted in Government Medical college, Kozhikode, between January 2016 and June 2017. All patients who were clinically diagnosed as cases of infectious corneal ulcer in the Ophthalmology department, Government Medical College, Kozhikode were included in the study. Corneal scrapings collected from the infected eye were subjected to microbiological examination and culture. A total of 120 cases were analysed. Each patient was examined with the slit lamp bio microscope after staining with fluorescein. Scrapings from cornea at the site of corneal ulcer were collected by ophthalmologist after a detailed clinical history and examination of the affected eye. The laboratory procedures used in the diagnosis of infectious keratitis were based on direct visualization of organisms by subjecting corneal scrapings to Gram stain and KOH wet mount and inoculation of material on to blood agar and Sabouraud dextrose agar. RESULTS Among the 120 cases, a total of 49 cases were culture positive. Twenty-one [17.5 %] were bacterial, twenty-two [18.34 %] were fungal and six [5.0 %] were poly microbial [bacteria and fungus]. Among the fungal aetiology, fusarium species was most common [32.14 %], followed by aspergillus species - 25.0 %. Trauma was the major risk factor. Diabetes mellitus, exposure keratitis were the other comorbidities / risk factors. CONCLUSIONS This study shows majority of infected corneal ulcers are associated with risk factors and the aetiology are mainly fungi. Microscopy, culture, and clinical correlation helped in adequate management. Thus, prognosis and outcome of corneal ulcers rely on timely identification of their aetiology and prompt treatment. KEY WORDS Corneal ulcer, Fungal Keratitis


Author(s):  
Khan I. Aqeel ◽  
S. K. Misra

Background: Internet has become an essential part of one’s life in this modern era where technology is taking over the world. Risk of Internet addiction (IA) has increased in this year 2020, due to Coronavirus disease 2019 (COVID-19) pandemic, where most of time students are restricted to their homes thus relying on social media to be in touch with outer world, moreover surfing of web, as well as online learning practices increased their screen and internet exposure time. Hence, we conducted a study to assess internet addiction among medical undergraduate students of Government Medical College in Agra.Methods: This descriptive cross-sectional study was conducted among 600 medical undergraduate students of S.N. Medical College, Agra. A self-administered, pre-validated questionnaire was used and a total of 488 students responded. E-questionnaire consist of questions about demographic information and internet usage pattern, it also contains Young’s IA test scale to measure internet addiction. Data obtained was analyzed and inferences were drawn.Results: The prevalence of IA was 61.5%. Mean ± Standard deviation (SD) age of the participants was 22.27±1.59 years and 48.36% were males. IA was significantly associated with male students, higher family income group and higher year of academic course. IA was also statistically significant with higher number of years since using internet, greater screen and internet usage time.Conclusion: Internet addiction is a growing problem among students of professional courses especially in medical colleges. IA has psychological, physical, and social impact on student’s life. So, it is necessary to develop strategies for prevention of internet addiction.


Author(s):  
Visakh T ◽  
Suresh Sukumar ◽  
Abhimanyu Pradhan

Objective: The objective of this study was to estimate the entrance surface radiation dose to the thyroid region in a computed tomography (CT) brain scan.Methods: Unfors Multi-O-Meter equipment was used to measure the entrance surface at the thyroid region of adult patients ranging from 18 to 70 years of age. A total of 115 patients were included in the study based on convenience sampling. The Multi-O-Meter was kept at the thyroid region during the scan, and the values for entrance surface dose (ESD) were noted from its monitor after the scan was complete.Results: The obtained data were analyzed and violate normal distribution; therefore, the median and quartiles were computed. The overall median (Q1, Q2), ESD of the patients, was 1.335 (1.213, 1.529) mGy. The minimum and maximum dose values recorded were 1.015 mGy and 1.964 mGy, respectively.Conclusions: The result showed a significant amount of entrance surface radiation dose to the thyroid region while taking a brain scan. This data can be used for optimization of radiation protection while undergoing CT scans of brain to reduce exposure to thyroid region.


2012 ◽  
Vol 1 (1) ◽  
pp. 65-67
Author(s):  
Dibya Tulachan ◽  
Rajesh Yadav ◽  
Bindu Gurung

Complex partial seizures are characterized by altered awareness of the self and the environment. Consciousness is retained unless secondary generalization occurs. Apart from the area and automatism patients may also experience odd disturbances of thought, emotion, deza vu, Jamai’s vu. depersonalization, derealization or even vivid hallucination of past experience (experiential phenomena). Here we report an adolescent lady presenting with non-convulsive status epileptics manifesting in the form of mood disorder with grandiose delusions of increased ability and identity as well as erotomania. Radio imaging and EEG revealed an epileptic focus originating from the parieto-temporal region. The case report cautions against an organic epileptic seizure that might be mistaken for dissociative, pseudodmentia, paranoid psychosis or even schizophrenia.DOI: http://dx.doi.org/10.3126/jonmc.v1i1.7290 Journal of Nobel Medical College Vol.1(1) 2011 65-67


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