Local hospital experience of emergency management in the response to SARS (Preprint)

2020 ◽  
Author(s):  
Ying Yan
Keyword(s):  
Emergency Management ◽  
Infection Prevention ◽  
Public Health Emergency ◽  
The Novel ◽  
Prevention Measures ◽  
Hospital Emergency ◽  
Local Hospital ◽  
Referral Network ◽  
Novel Coronavirus ◽  
Hospital Transmission

UNSTRUCTURED The ongoing outbreak of SARS-CoV-2 infection was first identified in Wuhan, China at the late of 2019. Following the acceleration of the novel coronavirus spreading, person-person transmissions in family residences, hospitals and other public environments have led to a major public hazard in China. Currently, the SARS-CoV-2 outbreak has been further developed into a public health emergency of international concern. In response to an occurring pandemic, hospitals need an emergency strategy and plan to manage their space, staff, and other essential resources, therefore, to provide optimum care to patients involved. In addition, infection prevention measures urgently need to be implemented to reduce in-hospital transmission and avoid the occurrence of virus super-spreading. For hospitals without capacity to manage severe patients, a referral network is often needed. We present our successful field experience regarding hospital emergency management and local hospitals network model in response to SARS-CoV-2 emerging epidemic.

scholarly journals SARS-CoV-2/DENV co-infection: a series of cases from the Federal District, Midwestern Brazil

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Heidi Luise Schulte ◽  
José Diego Brito-Sousa ◽  
Marcus Vinicius Guimarães Lacerda ◽  
Luciana Ansaneli Naves ◽  
Eliana Teles de Gois ◽  
...  
Keyword(s):  
Clinical Signs ◽  
Federal District ◽  
Therapeutic Interventions ◽  
Diagnostic Process ◽  
The Novel ◽  
Prevention Measures ◽  
Laboratory Findings ◽  
Novel Coronavirus ◽  
The Impact

Abstract Background Since the novel coronavirus disease outbreak, over 179.7 million people have been infected by SARS-CoV-2 worldwide, including the population living in dengue-endemic regions, particularly Latin America and Southeast Asia, raising concern about the impact of possible co-infections. Methods Thirteen SARS-CoV-2/DENV co-infection cases reported in Midwestern Brazil between April and September of 2020 are described. Information was gathered from hospital medical records regarding the most relevant clinical and laboratory findings, diagnostic process, therapeutic interventions, together with clinician-assessed outcomes and follow-up. Results Of the 13 cases, seven patients presented Acute Undifferentiated Febrile Syndrome and six had pre-existing co-morbidities, such as diabetes, hypertension and hypopituitarism. Two patients were pregnant. The most common symptoms and clinical signs reported at first evaluation were myalgia, fever and dyspnea. In six cases, the initial diagnosis was dengue fever, which delayed the diagnosis of concomitant infections. The most frequently applied therapeutic interventions were antibiotics and analgesics. In total, four patients were hospitalized. None of them were transferred to the intensive care unit or died. Clinical improvement was verified in all patients after a maximum of 21 days. Conclusions The cases reported here highlight the challenges in differential diagnosis and the importance of considering concomitant infections, especially to improve clinical management and possible prevention measures. Failure to consider a SARS-CoV-2/DENV co-infection may impact both individual and community levels, especially in endemic areas.

scholarly journals Impact of joint management of a COVID-19 mother and her newborn on the virus transmission: a case report

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Maria Chiara De Nardo ◽  
Anna Rita Bellomo ◽  
Francesca Perfetti ◽  
Francesco Antonino Battaglia ◽  
Miriam Lichtner ◽  
...  
Keyword(s):  
Infection Prevention ◽  
Virus Transmission ◽  
The Novel ◽  
Transplacental Transmission ◽  
Prevention Measures ◽  
Infected Mother ◽  
Case Presentation ◽  
Joint Management ◽  
Healthy Neonate

Abstract Background Since last year, COVID-19, the disease caused by the novel Sars-Cov-2 virus, has been globally spread to all the world. COVID-19 infection among pregnant women has been described. However, transplacental transmission of Sars-Cov-2 virus from infected mother to the newborn is not yet established. The appropriate management of infants born to mothers with confirmed or suspected COVID-19 and the start of early breastfeeding are being debated. Case presentation We report a case of the joint management of a healthy neonate with his mother tested positive for Covid-19 before the delivery and throughout neonatal follow-up. The infection transmission from the mother to her baby is not described, even after a long period of contact between them and breastfeeding. Conclusion It may consider an appropriate practice to keep mother and her newborn infant together in order to facilitate their contact and to encourage breastfeeding, although integration with infection prevention measures is needed.

scholarly journals Cutaneous presentation of COVID-19 Case Report

2020 ◽  
Vol 3 (3) ◽  
pp. 01-02
Author(s):  
Khadiga Ismail
Keyword(s):  
Public Health Emergency ◽  
World Health ◽  
The Novel ◽  
Scientific Journals ◽  
Global Public Health ◽  
The World ◽  
Global Spread ◽  
Novel Coronavirus ◽  
Health Organization ◽  
Recent Attention

COVID-19 has high transmissibility and infectivity among human. On January 30, 2020, the World Health Organization (WHO) in an effort to slow down the global spread of the virus declared the outbreak, “A global public health emergency of international concern". The skin manifestations of the novel coronavirus COVID-19 were not recognized at the early stages of the pandemic but have received much recent attention in scientific journals. Reported manifestations range from pseudo-chilblains to a morbilliform (measles-like) exanthem, urticaria, vesicular eruptions, a dengue-like petechial rash and ovate scaling macules, and plaques mimicking pityriasis rosea.

scholarly journals Structure-based Design of Prefusion-stabilized SARS-CoV-2 Spikes

2020 ◽  
Author(s):  
Ching-Lin Hsieh ◽  
Jory A. Goldsmith ◽  
Jeffrey M. Schaub ◽  
Andrea M. DiVenere ◽  
Hung-Che Kuo ◽  
...  
Keyword(s):  
Room Temperature ◽  
Protein A ◽  
Public Health Emergency ◽  
High Yield ◽  
The Novel ◽  
Yield Production ◽  
Novel Coronavirus ◽  
Serological Diagnostics ◽  
High Yield Production

ABSTRACTThe COVID-19 pandemic caused by the novel coronavirus SARS-CoV-2 has led to accelerated efforts to develop therapeutics, diagnostics, and vaccines to mitigate this public health emergency. A key target of these efforts is the spike (S) protein, a large trimeric class I fusion protein that is metastable and difficult to produce recombinantly in large quantities. Here, we designed and expressed over 100 structure-guided spike variants based upon a previously determined cryo-EM structure of the prefusion SARS-CoV-2 spike. Biochemical, biophysical and structural characterization of these variants identified numerous individual substitutions that increased protein yields and stability. The best variant, HexaPro, has six beneficial proline substitutions leading to ∼10-fold higher expression than its parental construct and is able to withstand heat stress, storage at room temperature, and multiple freeze-thaws. A 3.2 Å-resolution cryo-EM structure of HexaPro confirmed that it retains the prefusion spike conformation. High-yield production of a stabilized prefusion spike protein will accelerate the development of vaccines and serological diagnostics for SARS-CoV-2.

scholarly journals Detecting Twitter's Impact on COVID-19 Pandemic in India

2020 ◽  
Vol 9 (8) ◽  
pp. 815-819
Keyword(s):  
Social Media ◽  
Large Population ◽  
Signs And Symptoms ◽  
Public Health Emergency ◽  
Prevention Measures ◽  
The World ◽  
National Unit ◽  
System 2 ◽  
Novel Coronavirus ◽  
Global Solidarity

India has etched a higher place in the economy as a fast growing country with a large population. India is one of the leading Twitter usage countries, with 13.15 million users as ofApril2020[1].A novel coronavirus(COVID-19), which is a pand emic, has been threatening nearly everywhere. This terrible disea se started at the end of 2019 from WUHAN in China and is sprea ding very quickly virtually all over the world. This disease's whist leblower Dr. Li Wenliang also died from coronavirus on Feb 7, 2 020.According to the WHO, on 30 January 2020, the outbreak w as declared a public health emergency. In response to COVID19 he called for National Unit and Global Solidarity. All the countries in the world are linked with each other due to globalization, the proportion of labor finances migrating economically. In this paper, Twitter reflects the reality of the world. The main issue like signs and symptoms, prevention measures, and medicines which are related to this disease are discussed. Twitter is used for detecting this disease by analyzing data on social media. Nowadays social media sites are very fast and less costly for communication and exchange of information, ideas, and thoughts. This disease is being monitored by Twitter. If there is any delay it will result in a big damage to not only society but also the country. There are two methods: 1. Monitoring system 2. Awareness and alertness

scholarly journals Early spread of COVID-19 in Romania: imported cases from Italy and human-to-human transmission networks

2020 ◽  
Vol 7 (7) ◽  
pp. 200780 ◽  
Author(s):  
Marian-Gabriel Hâncean ◽  
Matjaž Perc ◽  
Jürgen Lerner
Keyword(s):  
Human Mobility ◽  
Structural Features ◽  
The Novel ◽  
Prevention Measures ◽  
Transmission Networks ◽  
Time Dynamics ◽  
Source Of Infection ◽  
Imported Cases ◽  
Geographical Dispersion ◽  
Novel Coronavirus

We describe the early spread of the novel coronavirus (COVID-19) and the first human-to-human transmission networks, in Romania. We profiled the first 147 cases referring to sex, age, place of residence, probable country of infection, return day to Romania, COVID-19 confirmation date and the probable modes of COVID-19 transmissions. Also, we analysed human-to-human transmission networks and explored their structural features and time dynamics. In Romania, local cycles of transmission were preceded by imported cases, predominantly from Italy. We observed an average of 4.8 days (s.d. = 4.0) between the arrival to a Romanian county and COVID-19 confirmation. Furthermore, among the first 147 COVID-19 patients, 88 were imported cases (64 carriers from Italy), 54 were domestic cases, while for five cases the source of infection was unknown. The early human-to-human transmission networks illustrated a limited geographical dispersion, the presence of super-spreaders and the risk of COVID-19 nosocomial infections. COVID-19 occurred in Romania through case importation from Italy. The largest share of the Romanian diaspora is concentrated especially in the northern parts of Italy, heavily affected by COVID-19. Human mobility (including migration) accounts for the COVID-19 transmission and it should be given consideration while tailoring prevention measures.

scholarly journals P123 The effect of having volunteers and face masks present at hospital entrances on the wearing of face masks and hand washing

BJS Open ◽  
2021 ◽  
Vol 5 (Supplement_1) ◽  
Author(s):  
Paul B Stanier ◽  
Savneet K Lochab ◽  
John E Grice ◽  
Paul B Stanier ◽  
Savneet K Lochab
Keyword(s):  
Hand Hygiene ◽  
General Hospital ◽  
Infection Prevention ◽  
Cost Effective ◽  
District General Hospital ◽  
Hand Washing ◽  
Prevention Measures ◽  
Hygiene Measures ◽  
Improve Compliance ◽  
Hospital Transmission

Abstract Background The spread of COVID-19 has put inpatients lives at risk and increased stress on hospital. Simple, cost effective measures such as mask wearing and hand hygiene have been shown to reduce the spread of droplet borne viruses. Compliance with these measures is variable and when performed improperly, reduce efficacy. Objective In this paper we aim to determine whether the provision of masks at hospital entrances and the use of volunteers to ensure correct mask wearing and hand hygiene can improve compliance with infection prevention measures for COVID-19. Method Visitor and staff compliance with mask wearing and hand hygiene measures were observed with and without the presence of masks and volunteers at hospital entrances at a District General Hospital. Results A total of 519 people were observed entering the hospital. Mask wearing went from 71% to 99% (P = <0.001) with the addition of volunteers. Provision of masks increased mask wearing from 56% to 97% (P = <0.001). Hand hygiene was improved from 9% to 84% (P = <0.001) with the presence of volunteers. Discussion A statistically significant improvement in hand hygiene and correct mask wearing was seen with both the presence of volunteers at hospital entrances and with the provision of masks. This is a relatively small study with heterogenous cohorts of staff and visitors. However, these results appear to indicate that use of volunteers and provision of masks at entrances may improve the compliance with the measures that been shown to reduce the in-hospital transmission of COVID-19.

scholarly journals FRONTLINE: The sociology of a pandemic: Countering a COVID 'disinfodemic' with a campus media initiative

2020 ◽  
Vol 26 (2) ◽  
pp. 179-200
Author(s):  
David Robie ◽  
Sri Krishnamurthi
Keyword(s):  
Prime Minister ◽  
Public Health Emergency ◽  
Asia Pacific ◽  
The Novel ◽  
The Pacific ◽  
Global Spread ◽  
Decisive Action ◽  
Novel Coronavirus ◽  
Mass Circulation ◽  
Flow Of Information

Parallel with the global spread of the novel coronavirus pandemic, a dangerous ‘disinfodemic’ has been infecting the flow of information worldwide. Communication and media outlets have faced a new challenge with not only being responsible for reportage and analysis of a fast-moving public health emergency—the biggest this century, but forced to sift through the mass circulation of falsehoods that have spread as rapidly as the virus. Concerned about the risks for both health and public responses to disinformation, United Nations Secretary-General António Guterres identified the ‘new enemy’ as a ‘growing surge of disinformation’. The UN launched a COVID-19 Communications for Solidarity Initiative to rapidly inform people about facts and science and to ‘promote and inspire acts of humanity’ globally. New Zealand is one of the few countries in the world whose strategy of COVID elimination has been a sustained approach to ‘keep the virus out, find it and stamp it out’. Evoking a theme of ‘our team of five million’ and national kindness, Prime Minister Jacinda Ardern has led a remarkable campaign blending decisive action and transparency. In this context, this article critically examines a four-month ‘Coronavirus Plus’ initiative conducted by the Pacific Media Centre at a communication programme in one of the New Zealand’s universities in response to the pandemic, deploying the Asia Pacific Report website, asiapacificreport.nz. 

scholarly journals WEATHERING THE STORM: VIET NAM’S LEGAL AND POLICY MEASURES IN THE TIME OF COVID-19

2020 ◽  
Vol 0 (6) ◽  
pp. 7-32
Author(s):  
Duc Tien Nguyen ◽  
◽  
An Thanh T. Chu ◽  
Keyword(s):  
Public Health ◽  
Public Health Emergency ◽  
The Novel ◽  
Public Governance ◽  
Information Transparency ◽  
Policy Initiatives ◽  
Policy Measures ◽  
Key Features ◽  
Entire World ◽  
Novel Coronavirus

The novel coronavirus has shaken the entire world to its roots. Yet, governments’ responses have taken many forms. Some countries were able to flatten the curve, while others struggled to pick up the pieces. This article provides governance implications drawn from Viet Nam’s COVID-19 experience. Accordingly, the country’s key features of its COVID-19 responses include resolute leadership, information transparency, central – local government coordination, public participation, and adequate preparedness. Besides, this article also highlights some of Viet Nam’s key legislative and policy initiatives in a bid to cautiously keep the pandemic under control and the economy rolling. By doing so, it makes a practical contribution to the discourse on public governance in the time of a public health emergency.

Impact of Corona virus Outbreak on Climate and air Quality

2021 ◽  
Vol 16 ◽  
Author(s):  
Nikita Jatai ◽  
Tanu Sharma ◽  
Karan Veer
Keyword(s):  
Public Health ◽  
Acute Respiratory Distress Syndrome ◽  
Distress Syndrome ◽  
Public Health Emergency ◽  
The Novel ◽  
Symptomatic Case ◽  
The People ◽  
The World ◽  
Novel Coronavirus

All over the world, there is a new target of public health emergency looming the world along with an appearance and distribution of the novel coronavirus disease (2019-nCoV) also known as Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2). This Virus initially generated in bats and then after transferred to a human being over unknown animal playing the role of mediator in Wuhan, China in December 2019. This virus is passed by breathing or in contact with an infected person’s droplets. The Incubation period is between 2 to 14 days for COVID-19, that is the time between exposure of the virus (person becoming infected) and symptom on that person, is on an average of 5-6 days, however it can goes up to 14 days. Throughout this period, which can be also known as “pre-symptomatic” period, some of the infected patients or persons can be contagious. That is why, transferal from a pre-symptomatic case can happen before the symptoms onset. Where there is few number of case studies and reports, pre-symptomatic transferal has been documented via contact with someone who is diagnosed with virus and increase investigation of that particular clusters of total confirmed cases. The main problem is that the symptoms are just like the regular flu that are cough, fever, sore throat, fatigue and breathlessness. This virus is moderate or mild in most of the people, but in elder ones, it may proceed to pneumonia, multi-organ dysfunction and Acute Respiratory Distress Syndrome (ARDS). Coronavirus has significant consequences on the Health system, mainly on cardiovascular diseases and on the environment.

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