scholarly journals ANTI-INFLAMMATORY, ANALGESIC AND ANTIOXIDANT ACTIVITIES OF HYDRO-ACETONIC EXTRACT FROM WISSADULA AMPLISSIMA VAR. ROSTRATA (SHUM. AND THONN.) R. E. FRIES

2018 ◽  
Vol 10 (8) ◽  
pp. 113
Author(s):  
Emmanuel A. M. Thiombiano ◽  
Noufou Ouedraogo ◽  
Martin Kiendrebeogo ◽  
Marius Lompo
Keyword(s):  
Lipid Peroxidation ◽  
Acute Toxicity ◽  
Xanthine Oxidase ◽  
Antioxidant Activities ◽  
Colorimetric Method ◽  
Aluminium Chloride ◽  
Total Phenolic ◽  
Antioxidant Power ◽  
Anti Inflammatory ◽  
Analgesic Activities

Objective: The present study aims to investigate anti-inflammatory, analgesic and antioxidant effects of the hydroacetonic extract (HAE) from Wissadula amplissima whole plant and to determine its polyphenol and flavonoid contents.Methods: Extraction was achieved by soaking defatted W. amplissima with aqueous acetone solvent. Acute toxicity and pharmacological investigations were performed per os and intraperitoneally on Naval Medical Research Institute (NMRI) mice. The carrageenan-induced paw edema and the acetic acid-induced writhing tests were used to assess the in vivo anti-inflammatory and analgesic activities. Inhibition of xanthine oxidase and lipoxygenase were carried out in vitro using endpoint spectrophotometric assays at 295 nm and 234 nm. 2,2-diphenyl-1-picrylhydrazyl (DPPH), Ferric Reducing Antioxidant Power (FRAP), lipid peroxidation and desoxyribose degradation assays were used to point out antioxidant activities of extract. Aluminium chloride colorimetric method was used to determine total flavonoids content when and total phenolic content was measured by the method Folin-ciocalteu reagent.Results: W. amplissima’s HAE exhibited a slight acute toxicity with no lethality observed. Significant (p<0.05) anti-inflammatory and analgesic activities were recorded as well as strong inhibitory activities on lipoxygenase and xanthine oxidase. W. amplissima’s HAE also demonstrated interesting antioxidant activities particularly in preventing lipid peroxidation. Polyphenol and flavonoid contents were respectively estimated to 64.33±1.34 mg Gallic Acid Equivalent (GAE) and 35.17±0.77 mg Quercetin Equivalent (QE) per 100 mg of W. amplissima’s HAE.Conclusion: HAE of W. amplissima exhibited a promising anti-inflammatory and analgesic potential compared to the reference (acetylsalicylic acid, Hydrocortisone, paracetamol) and regarding the inhibition of lipoxygenase and lipid peroxidation. The anti-inflammatory and analgesic activities seem to be related to the antioxidant and enzymes inhibitors compounds of the plant extract. 

scholarly journals Total Phenolic Content, Flavonoid Content and Antioxidant Potential of Wild Vegetables from Western Nepal

Plants ◽  
2019 ◽  
Vol 8 (4) ◽  
pp. 96 ◽  
Author(s):  
Sushant Aryal ◽  
Manoj Kumar Baniya ◽  
Krisha Danekhu ◽  
Puspa Kunwar ◽  
Roshani Gurung ◽  
...  
Keyword(s):  
Phenolic Content ◽  
Colorimetric Method ◽  
Radical Scavenging ◽  
Aluminium Chloride ◽  
Total Phenolic ◽  
Scavenging Activity ◽  
Flavonoid Content ◽  
Antioxidant Power ◽  
Wild Vegetables ◽  
Ic50 Value

Eight selected wild vegetables from Nepal (Alternanthera sessilis, Basella alba, Cassia tora, Digera muricata, Ipomoea aquatica, Leucas cephalotes, Portulaca oleracea and Solanum nigrum) were investigated for their antioxidative potential using 2,2-dyphenyl-1-picrylhydrazyl (DPPH) scavenging, hydrogen peroxide (H2O2), ferric reducing antioxidant power (FRAP), and ferric thiocyanate (FTC) methods. Among the selected plant extracts C. tora displayed the highest DPPH radical scavenging activity with an IC50 value 9.898 μg/mL, whereas A. sessilis had the maximum H2O2 scavenging activity with an IC50 value 16.25 μg/mL—very close to that of ascorbic acid (16.26 μg/mL). C. tora showed the highest absorbance in the FRAP assay and the lowest lipid peroxidation in the FTC assay. A methanol extract of A. sessilis resulted in the greatest phenolic content (292.65 ± 0.42 mg gallic acid equivalent (GAE)/g) measured by the Folin–Ciocalteu reagent method, while the smallest content was recorded for B. alba (72.66 ± 0.46 GAE/g). The greatest flavonoid content was observed with extracts of P. oleracea (39.38 ± 0.57 mg quercetin equivalents (QE)/g) as measured by an aluminium chloride colorimetric method, while the least was recorded for I. aquatica (6.61 ± 0.42 QE/g). There was a strong correlation between antioxidant activity with total phenolic (DPPH, R2 = 0.75; H2O2, R2 = 0.71) and total flavonoid content (DPPH, R2 = 0.84; H2O2, R2 = 0.66). This study demonstrates that these wild edible leafy plants could be a potential source of natural antioxidants.

scholarly journals Antioxidant Potential of Selected Korean Edible Plant Extracts

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Yaejin Woo ◽  
Hyeji Lee ◽  
Yong-Seob Jeong ◽  
Ga Young Shin ◽  
Ja Gyeong Oh ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Plant Extracts ◽  
Antioxidant Activities ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Biologically Active ◽  
Total Phenolic ◽  
Edible Plant ◽  
Camellia Japonica ◽  
Antioxidant Power

This study aimed to evaluate the antioxidant activity of various plant extracts. A total of 94 kinds of edible plant extracts obtained from the Korea Plant Extract Bank were screened for cytotoxicity, following which the total phenolic content of 24 shortlisted extracts was determined. Of these, extracts from three plants, namely, Castanea crenata (CC) leaf, Camellia japonica (CJ) fruit, and Viburnum dilatatum (VD) leaf, were examined for antioxidant capabilities by measuring radical scavenging activity, ferric reducing/antioxidant power, and lipid peroxidation inhibitory activity. In addition, cellular antioxidant activities of the three extracts were assessed by a cell-based dichlorofluorescein assay and antioxidant response element (ARE) reporter activity assay. The results demonstrated that all three extracts concentration-dependently scavenged free radicals, inhibited lipid peroxidation, reduced the cellular level of reactive oxygen species, and increased ARE-luciferase activity, indicating antioxidant enzyme-inducing potential. In particular, CJ extract showed significantly greater antioxidative activity and antimigratory effect in a breast cancer cell line compared to CC and VD extracts. Hence, CJ extract deserves further study for its in vivo functionality or biologically active constituents.

scholarly journals Antioxidant and Anti-Inflammatory Activities of Caralluma Acutangula (Decne.) N.E.Br Extracts, a Medicinal Plant from Burkina Faso

2019 ◽  
Vol 9 (6) ◽  
pp. 155-161
Author(s):  
Pare Dramane ◽  
N’do Jotham Yhi-pênê ◽  
Hilou Adama
Keyword(s):  
Oxidative Stress ◽  
Hydrogen Peroxide ◽  
Lipid Peroxidation ◽  
Secondary Metabolites ◽  
Acute Toxicity ◽  
Xanthine Oxidase ◽  
Antioxidant Systems ◽  
Nmri Mouse ◽  
Good Activity ◽  
Anti Inflammatory

Plants have always played an important role in health care in Africa. The stress, a situation of imbalance between oxidizing and antioxidant systems in favor of the prooxidants is responsible for the installation of several pathologies such as cancers, cardiovascular diseases, diabetes ... The objective of this study was to highlight the presence Secondary metabolites in C. acutangula extract and determine its antioxidant and anti-inflammatory potential. For the determination of the acute toxicity of the extract, a dose of 2000 mg / kg was administered to the NMRI Mouse. The methods of screening were used to detect secondary metabolites like tannins, steroids and terpen, flavonoids, coumarins. The antioxidant capacity was evaluated in vitro by determining the ability of the extract to inhibit lipid peroxidation, hydrogen peroxide, degradation of deoxyribose. The anti-inflammatory potential was evaluated on lipoxygenase and xanthine oxidase. Acute toxicity evaluated in NMRI mice showed that the ethanolic extract of C. acutangula show no toxicity. Tannins, steroids and terpen, flavonoids, coumarins have been detected in the extracts. C. acutangula showed good activity with an inhibition of 50.71 ± 2.51% at 100 μg / ml on lipid peroxidation, of 66.105 ± 1.26% on deoxyribose degradation and 8.625 ± 1.09% on hydrogen peroxide. It showed good activity on xanthine oxidase with an 81.5 ± 5.5% inhibition. For the effect on lipoxygenase it gave an inhibition of the enzyme at 43.11 ± 3.4%. This potential could be used in the fight against inflammatory diseases and that due to oxidative stress. Keywords: antioxidant, anti-inflammatory, oxidative stress, lipid peroxidation

scholarly journals Evaluation of Antioxidant Activity and Acute Toxicity ofClausena excavataLeaves Extract

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Shaymaa Fadhel Abbas Albaayit ◽  
Yusuf Abba ◽  
Rasedee Abdullah ◽  
Noorlidah Abdullah
Keyword(s):  
Antioxidant Activity ◽  
Acute Toxicity ◽  
Methanolic Extract ◽  
Radical Scavenging Activity ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Aluminium Chloride ◽  
Total Phenolic ◽  
High Dose ◽  
Antioxidant Power

Clausena excavata(Lour.), locally known as “Kemantu hitam,” is a common plant in Malaysian folklore medicine. This study evaluated the antioxidant properties of the solvent extracts ofC. excavataleaves and determined the acute toxicity of methanolic extractC. excavata(MECE) leaves in Sprague-Dawley rats. Harvested leaves were dried and subjected to solvent extraction using petroleum ether, chloroform, ethyl acetate and methanol in succession. The antioxidant activity of each extract was determined using the ferric-reducing antioxidant power (FRAP) and 2,2-diphenyl-1-picryl dihydrazyl (DPPH) radical scavenging activity. The total phenolic content (TPC) and total flavonoids content (TFC) were estimated by Folin-Ciocalteu and ethanolic aluminium chloride method, respectively. The chloroform extract was found to be highest in flavonoid content, while the methanolic extract showed the highest TPC and antioxidant activity. There was no mortality in rats treated with MECE leaves even at a high dose of 5000 mg/kg body weight. However, the MECE leaves produced mild to moderate pathological changes in the liver and kidneys, shown by mild degenerative changes and leucocyte infiltration. The extract did not affect the haematological parameters or relative weights of the liver or kidneys. Overall, the MECE leaves have potent antioxidant activity and are presumed safe to be used orally as health-promoting product at low to moderate doses.

scholarly journals ANTI-INFLAMMATORY ACTIVITY AND PHYTOCHEMISTRY OF EXTRACTS FROM THE ROOT BARK OF CALOTROPIS PROCERA (AIT.) R. BR. HEPATOPROTECTIVE MEDICINAL PLANT FROM BURKINA FASO

2020 ◽  
pp. 185-190
Author(s):  
ERNEST NOGMA SOMBIÉ ◽  
NOUFOU OUÉDRAOGO ◽  
ADAMA HILOU
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Activities ◽  
Antioxidant Properties ◽  
Reducing Power ◽  
Ethanolic Extract ◽  
Calotropis Procera ◽  
Root Bark ◽  
Dpph Radical ◽  
Antioxidant Power ◽  
Anti Inflammatory

Objective: This study aimed to assess the anti-inflammatory and antioxidant properties in vitro of Calotropis procera root bark. Methods: Anti-inflammatory activities of the ethanolic extract of root bark of C. procera and its fractions were evaluated on lipoxygenase and xanthine oxidase (XO). Antioxidant activity was evaluated by trapping the 2,2-diphenylpicrylhydrazyl (DPPH) radical, hydrogen peroxide (H2O2), by the reducing power ferric reducing antioxidant power. Inhibitory powers of lipid peroxidation and of degradation of D-deoxyribose as well as the contents of phenolic and triterpene compounds were also evaluated. Results: Ethanolic extract showed interesting anti-inflammatory and antioxidant activities. Butanol fraction which is one of richest fractions for flavonoids (17.38±0.13 mg EQ/10 g extracts) showed the best percentages for inhibitions of XO (60.14±4.89%), degradation of D-deoxyribose (81.04±0.77%), and the DPPH radical (71.43±6.35%). Dichloromethane fraction which is the richest in triterpenes (1067.02±5.77 mg UAE/g extracts) showed the best percentages for inhibitions of lipoxygenase (56.45±1.15%) and of lipid peroxidation (82.45±0.73%). Ethyl acetate and residual aqueous fractions, respectively, showed the best activities of inhibiting H2O2 (75.38±0.76%) and for iron-reducing capacity (23.51±1.69 mg EAA/g extracts). Conclusion: Ethanolic extract from C. procera root bark and its fractions, their particular the butanol and dichloromethane one, has anti-inflammatory and antioxidant properties which could prevent or attenuate liver injury and its complications.

scholarly journals Phytochemical, Antioxidant and Anti-Inflammatory Effects of Extracts from Ampelocissus africana (Lour) Merr (Vitaceae) Rhizomes

2020 ◽  
pp. 8-18
Author(s):  
W. Leila Marie Esther Belem- Kabré ◽  
Noufou Ouédraogo ◽  
Adjaratou Compaoré- Coulibaly ◽  
Mariam Nebié- Traoré ◽  
Tata K. Traoré ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Activity ◽  
Aqueous Extract ◽  
Methanolic Extract ◽  
Total Phenolic ◽  
Antioxidant Power ◽  
Cox 2 ◽  
Anti Inflammatory ◽  
Cox 1

Aims: To determine the phytochemical composition and evaluate the antioxidant and anti-inflammatory properties of methanolic and aqueous extracts from Ampelocissus africana (Lour) Merr rhizomes. Study Design: Phytochemical content and screening, in vitro antioxidant and anti-inflammatory assays. Place and Duration of Study: Department of Traditional Pharmacopoeia and Pharmacy (MEPHATRA / PH) of the Institute for Research in Health Sciences (IRSS) and Laboratory of Applied Biochemistry and Chemistry (LABIOCA), University Joseph KI-ZERBO in Ouagadougou between April and August 2020. Methodology: The antioxidant activity of both extracts of the plant was assessed using DPPH radical scavenging, ABTS+ radical cation decolorization, ferric ion reduction and lipid peroxidation inhibition in rat liver assays. The anti-inflammatory activities in vitro were measured on the ability of the extract to inhibit the activity of enzymes such as 15-lipoxygenase, phospholipase A2 (PLA2) and cyclooxygenases (COX-1 and COX-2). Results: This study revealed that the total phenolic contents of the extracts varied from 471.79 ± 1.71 mg GAE/g to 173.88 ± 1.71 mg GAE/g for methanolic and aqueous extract respectively. The extracts were also rich in flavonoids and tannins. The methanolic extract possessed better antioxidant activity with an IC50 of 2.32 ± 0.18 µg/ml for the ABTS, 1.71 ± 0.05 µg/mL for the DPPH, a reducing power agent of 87.44 ± 0.5 mmol AAE /100 g and a percentage inhibition of lipid peroxidation of 52.21%. The methanolic and aqueous extract of A. africana has an inhibitory action on activity of lipoxygenase with IC50 values of 26.09 ± 1.83 μg/mL to 34.32 ± 1.60 μg/mL, respectively. The methanolic extract caused COX-1 inhibition of 36.07%, COX-2 inhibition of 38.31% and PLA2 inhibition of 26.9%. Conclusion: These results showed that the methanolic and aqueous extract from the rhizomes of Ampelocissus africana possessed antioxidant power, inhibitor effect against proinflammatory enzymes.

Optimization of Maclura cochinchinensis Extract as a Cosmeceutical Component for Antioxidant and Anti-Tyrosinase Activities

2020 ◽  
Vol 859 ◽  
pp. 188-193
Author(s):  
Boonyadist Vongsak ◽  
Sunan Jaisamut ◽  
Kanokporn Gonsap ◽  
Porntip Parmontree
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Activities ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Ethanol Extract ◽  
Bioactive Compound ◽  
Total Phenolic ◽  
Ultrasound Technique ◽  
Antioxidant Power ◽  
Chronic Fever

Maclura cochinchinensis Corner or Kae Lae in Thai belongs to the Moraceae family. The plant is found in Southeast Asian countries and used in traditional medicine as a tonic agent to treat chronic fever and skin infections. Previous studies have demonstrated that plants in Moraceae family, such as Morus alba and Artocarpus lakoocha are rich source of antioxidant and anti-tyrosinase agents. Thus, the current study aimed at comparing different solvent extracts (50% ethanol, 80% ethanol, methanol by ultrasound and water decoction) of M. cochinchinensis heartwood for their antioxidant and anti-tyrosinase activities. Total phenolic content, 2, 2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activity, ferric reducing antioxidant power (FRAP) and anti-lipid peroxidation assays were performed to compare the antioxidant activity, whereas, Dopachrome method was performed for anti-tyrosinase activity. The results demonstrated that 80% ethanol and methanol extracts had better antioxidant activities based on EC50 value of DPPH (9.96±0.21 and 9.50±0.46 μg/mL, respectively), ABTS (6.54±0.13 and 6.58±0.69 μg/mL, respectively), anti-lipid peroxidation (228.31±2.03 and 231.43±1.41 μg/mL, respectively), and anti-tyrosinase (7.60±0.29 and 7.91±0.41 μg/mL, respectively) assays. Further, 80% ethanol extract was selected to evaluate the bioactive compound using bioactivity-guided isolation. Oxyresveratrol identified as bioactive compound, exhibited higher activities than the positive controls (quercetin and kojic acid). In conclusion, 80% ethanolic M. cochinchinensis heartwood extract obtained using the ultrasound technique exhibited strong antioxidant and anti-tyrosinase effects and can be used as a potential active ingredient for cosmeceutical products. Oxyresveratrol could be used as bioactive marker for quality control of the extract and products.

Total Flavonoid and Phenolic Contents and Antioxidant Activities of Spermacoce Latifolia Extracts

2019 ◽  
Vol 18 (2) ◽  
pp. 191-195
Author(s):  
Luo Ying ◽  
Li Min-Min ◽  
Cao Zhao-Hui ◽  
Hu Xiao-Bo ◽  
Tang Shuang-Yang ◽  
...  
Keyword(s):  
Ethyl Acetate ◽  
Total Phenolics ◽  
Antioxidant Activities ◽  
Ethyl Acetate Fraction ◽  
Sulphonic Acid ◽  
Aluminium Chloride ◽  
Total Phenolic ◽  
Total Flavonoids ◽  
Antioxidant Power ◽  
Ferric Reducing Antioxidant Power

The present study compares different extraction methods for recovery of total phenolics and flavonoids from Spermacoce latifolia and their antioxidant properties. Total phenolic and flavonoid contents were assessed by Folin-Ciocalteu and aluminium chloride colorimetric method respectively, while antioxidant activities were evaluated by 1,1-diphenyl-2-picrylhydrazyl, 2,2′-azinobis-(3-ethylbenzthiazoline-6-sulphonic acid) and ferric reducing antioxidant power assays. Results showed that the n-butanol fraction exhibited the highest content of total phenolics (57.97 ± 1.99 mg gallic acid equivalents/g extract). Besides, the highest content of total flavonoids (168.16 ± 0.65 mg rutin equivalents/g extract) and the highest antioxidant activities of 1,1-diphenyl-2-picrylhydrazyl assay (SC50 = 51.44 ± 0.24 μg/mL), 2,2′-azinobis-(3-ethylbenzthiazoline-6-sulphonic acid) assay (SC50 = 10.94 ± 0.11 μg/mL), and ferric reducing antioxidant power assay (8.36 ± 0.10 mmol Fe(II)/g extract) were observed for the ethyl acetate fraction. The high level of total flavonoids in the ethyl acetate fraction might be the major contributors towards the antioxidant activity. To conclude, the ethyl acetate fraction of S. latifolia might be used as natural antioxidants.

scholarly journals Properties of Antioxidant and Anti-Inflammatory Activity and Phenolic Profiles of Şevketi Bostan (Cnicus benedictus L.) Cultivated in Aegean Region from Turkey

2017 ◽  
Vol 5 (4) ◽  
pp. 308 ◽  
Author(s):  
Zehra Can ◽  
Nimet Baltaş ◽  
Saban Keskin ◽  
Oktay Yıldız ◽  
Sevgi Kolaylı
Keyword(s):  
Xanthine Oxidase ◽  
High Performance ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Total Phenolic ◽  
Leaf Extracts ◽  
Antioxidant Power ◽  
Phenolic Profiles ◽  
Ferric Reducing Antioxidant Power ◽  
Anti Inflammatory

The aim of this work was to evaluate the phenolic profiles and anti-inflammatory, antioxidant and gastro-protective activities of Cnicus benedictus L., a type of milk thistle cultivated in Turkey. The total phenolic content (TPC), total flavonoid content (TFC), ferric reducing antioxidant power (FRAP) and the 2,2-diphenyl-1-picryhydrazyl (DPPH) free radical scavenging activity was measured to determine antioxidant capacity. The anti-urease and anti-xanthine oxidase activities were used to determine the gastro-protective and anti-inflammatory potential of the plant extracts, respectively. The TPC was 337.40 and 635.10 mg of gallic acid equivalents (GAE)/100 g and TFC was 41.05 -119.12 mg of quercetin equivalents (QE)/100 g in the root and leaf extracts, respectively. The root and leaf extracts of Cnicus benedictus L., were exhibited different inhibition values against both of the enzymes. The inhibition effect of the both enzymes were calculated as IC50 (mg/mL) in terms of 50% inhibition of the enzymes. The xanthine oxidase activity of the leaf and root was 18.53 and 19.75 mg/mL and the urease activity were 2.29 mg/mL and 11.53 mg/mL, respectively. Fifteen phenolic compounds were determined by high-performance liquid chromatography (HPLC-UV). Vanillic, silibinin B, ferulic acid and rutin were found major amount of the plant. In conclusion, the plant have high potential beneficial nutraceuticals and consumption of the together with its roots and leafs will be beneficial in terms of nutrition.

scholarly journals HPLC-UV profile of Genista ulicina Spach. (Fabaceae) extracts and in vitro antioxidant activity

2016 ◽  
Vol 8 (3) ◽  
pp. 398 ◽  
Author(s):  
Kaoutar Chebbah ◽  
Eric Marchioni ◽  
Djamel Sarri ◽  
Ahmed Menad ◽  
Ratiba Mekkiou ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Activities ◽  
Colorimetric Method ◽  
Aluminium Chloride ◽  
Total Phenolic ◽  
Uv Detector ◽  
Etoac Extract ◽  
Phenolic And Flavonoid ◽  
Β Carotene

<p>To perform a qualitative and quantitative analysis of the phenolic and flavonoid contents and evaluate the antioxidant activity of ethyl acetate (EtOAc) and <em>n</em>-butanol (<em>n</em>-BuOH) extracts of the aerial parts of <em>Genista ulicina </em>Spach. from Algeria.<strong> </strong>The qualitative analysis of plant extracts was carried out by RP-HPLC using UV detector, whereas the quantification of total phenolic and flavonoid contents was completed according to the Folin-Ciocalteu procedure and aluminium chloride colorimetric method respectively. To evaluate the extract's antioxidant activity, Two in vitro antioxidant tests were employed: DPPH and β-carotene bleaching assay. The HPLC/DAD chromatogram showed several peaks indicating the presence of phenolic acids, flavonoids and isoflavonoids in both extracts. The total phenolic content (TPC) ranged from 62.56 and 50.45 mgGAE/g extract, while the total flavonoids content varied between 53.1 and 48.4 mgQE/g extract for EtOAC and <em>n</em>-BuOH respectively. EtOAc extract showed a maximum inhibition value (78.15%) at 150µg/mL using DPPH test and highest antioxidative power (82.42%) using β-carotene bleaching assay comparing with standards. The HPLC-UV analysis showed the richeness of both extracts in phenolic and flavonoid contents. The EtOAc<em> </em>extract exhibited good antioxidant activities comparing to the <em>n</em>-BuOH extract. Thus <em>Genista ulicina</em> could be indicated as a plant of phytopharmaceutical importance.<strong></strong></p>

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