Canine lymphoma: Pathological and clinical characteristics of patients treated at a referral hospital

Non-Hodgkin’s lymphomas are common canine cancers with variable demographic and clinical presentations. Their pathological characterization and treatment lag far behind those of humans. We describe consecutive lymphoma patients detected over a one-year period at the National Autonomous University of Mexico (UNAM). Of 4,512 dogs: 220 (4.9%) had a cancer diagnosis, of which 27 (0.6%) had lymphoma (12% of cancer patients). We found an association with Miniature Schnauzers, which represented 18.5% (5/27) of lymphoma patients, but it was only 6.4% (288/4,512) of the dogs studied in this time period (p < 0.011). Miniature Schnauzers and mongrels together constituted nearly half of lymphoma cases. Mean age at diagnosis was 7.5 years (3-14), with a female to male ratio of 1.7:1. We found no correlation between lymphoma and castration status. Most patients presented nodal involvement (80%), were in advanced stages III/IV (90%) and had B-cell versus T-cell tumors (64%/36%). Only two histopathological patterns were seen, both with diffuse nodal-replacement by large immunoblast and/or centroblast-like cells; one having numerous tingible-body macrophages which are suggestive of a high proliferative rate. Chemotherapy was given to 15 patients (65%) with an overall response of 73% (3 complete responses/8 partial responses) and a mean overall survival of 219 days (4-586; SD±185). One cutaneous lymphoma-patient achieved partial response (PR) with lomustine/prednisone, and treatment was still ongoing at 548 days. Earlier diagnosis, better lymphoma subtype distinction, and specific curative treatments are needed.

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One Year of the COVID-19 Pandemic in Galicia: A Global View of Age-Group Statistics during Three Waves

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18105104 ◽

2021 ◽

Vol 18 (10) ◽

pp. 5104

Author(s):

Iván Area ◽

Henrique Lorenzo ◽

Pedro J. Marcos ◽

Juan J. Nieto

Keyword(s):

Intensive Care Unit ◽

Hospital Admissions ◽

Age Groups ◽

Age Group ◽

Nw Spain ◽

The Past ◽

Global View ◽

Time Period ◽

Key Variables ◽

One Year

In this work we look at the past in order to analyze four key variables after one year of the COVID-19 pandemic in Galicia (NW Spain): new infected, hospital admissions, intensive care unit admissions and deceased. The analysis is presented by age group, comparing at each stage the percentage of the corresponding group with its representation in the society. The time period analyzed covers 1 March 2020 to 1 April 2021, and includes the influence of the B.1.1.7 lineage of COVID-19 which in April 2021 was behind 90% of new cases in Galicia. It is numerically shown how the pandemic affects the age groups 80+, 70+ and 60+, and therefore we give information about how the vaccination process could be scheduled and hints at why the pandemic had different effects in different territories.

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Survival With Respect to Morphology in Pulmonary Atresia and Intact Ventricular Septum in Sweden

World Journal for Pediatric and Congenital Heart Surgery ◽

10.1177/2150135120958641 ◽

2021 ◽

Vol 12 (1) ◽

pp. 27-34

Author(s):

Stina Manhem ◽

Katarina Hanséus ◽

Håkan Berggren ◽

Britt-Marie Ekman-Joelsson

Keyword(s):

Pulmonary Atresia ◽

Early Time ◽

Ventricular Septum ◽

Intact Ventricular Septum ◽

Early Group ◽

Time Period ◽

Medical Reports ◽

One Year ◽

Survival Risk ◽

Late Group

Background: Patients born with pulmonary atresia and intact ventricular septum represent a challenge to pediatric cardiologists. Our objective was to study changes in survival with respect to morphology in all children born with pulmonary atresia and intact ventricular septum in Sweden during 36 years. Methods: A retrospective, descriptive study based on medical reports and echocardiographic examinations consisting of those born between 1980 and 1998 (early group) and those born between 1999 and 2016 (late group). Results: The cohort consists of 171 patients (early group, n = 86 and late group, n = 85) yielding an incidence of 4.35 and 4.46 per 100,000 live births, respectively. One-year survival in the early group was 76% compared to 92% in the late group ( P = .0004). For patients with membranous atresia, one-year survival increased from 78% to 98%, and for muscular pulmonary atresia, from 68% to 85%. In patients with muscular pulmonary atresia and ventriculocoronary arterial communications, there was no significant increase in survival. Risk factors for death were being born in the early time period hazard ratio (HR), 6; 95% CI (2.33-14.28) P = .0002, low birth weight HR, 1.26; 95% CI (1.14-1.4) P < .0001 and having muscular pulmonary atresia HR, 3.74; 95% CI (1.71-8.19) P = .0010. Conclusion: The incidence of pulmonary atresia and intact ventricular septum remained unchanged during the study period. Survival has improved, especially for patients with membranous pulmonary atresia, while being born with muscular pulmonary atresia is still a risk factor for death. To further improve survival, greater focus on patients with muscular pulmonary atresia and ventriculocoronary arterial communications is required.

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A Case of Incidentally Detected Bladder Lipoma and a Review of the Literature

Current Medical Imaging Formerly Current Medical Imaging Reviews ◽

10.2174/1573405617666210712122127 ◽

2021 ◽

Vol 17 ◽

Author(s):

Emre Emekli ◽

Elif Gündoğdu

Keyword(s):

Histopathological Examination ◽

Adrenal Adenoma ◽

Bladder Wall ◽

Benign Tumors ◽

Imaging Features ◽

Multiplanar Reconstructions ◽

Clinical Presentations ◽

Pelvic Lipomatosis ◽

One Year

Background: Lipomas are benign fatty tumors made of fat tissue. Bladder lipomas are extremely rare. For this reason, it is necessary to be aware of the imaging features when incidentally detected in imaging. Case Report: In the abdominal computed tomography (CT) performed as part of the follow-up examination of a 43-year-old patient, who had undergone surgery for adrenal adenoma five years earlier, a 14x9x8 mm smoothly marginated, ovoid-shaped, hypodense mass lesion with a homogeneous internal structure was detected in the anterior bladder wall. The pre-contrast density of the lesion was measured as -105 HU. The magnetic resonance imaging performed one year after the CT examination revealed a 14x9x8 intramural mass in the bladder wall, showing protrusion toward the lumen. The group was observed to be markedly hypointense on fat-suppressed T1 and T2-weighted images and considered consistent with a bladder lipoma. Discussion: Bladder lipomas are benign lesions that can vary in clinical presentations but usually cause hematuria. The differential diagnosis of bladder lipomas includes other mesenchymal rare benign tumors that can arise from the urinary bladder submucosal layer, including leiomyoma, hemangioma, plasmacytoma, fibroma, and neurofibroma, in imaging bladder lipomas present as homogeneous lesions containing macroscopic fat. Only the liposarcoma and pelvic lipomatosis could also show similar features. The less differentiated liposarcomas tend to present more heterogeneous enhancement, irregular-shaped margins, and infiltrative behavior. Also, appropriate multiplanar reconstructions may allow the radiologist to determine it is an extravesical pelvic lipomatosis. Conclusion: Using CT and MRI, these lesions rich in adipose tissue can be distinguished from other lesions, and their diagnosis can be made to a great extent. However, a histopathological examination is required for a definitive diagnosis.

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Can Individual Investors Capture The Value Premium?

Journal of Business & Economics Research (JBER) ◽

10.19030/jber.v7i5.2287 ◽

2011 ◽

Vol 7 (5) ◽

Author(s):

Patrick J. Larkin

Keyword(s):

Individual Investors ◽

Investment Strategies ◽

Enterprise Value ◽

Market Portfolio ◽

A Value ◽

Time Period ◽

Return On Capital ◽

Reduce Risk ◽

One Year ◽

Value Strategy

I test the performance of several simple one and two-factor mechanical GARP and value investment strategies against a value-weighted market portfolio for the period 1998-2006, focusing on the suitability of the strategies for individual investors. All of the GARP and value strategies produce substantially higher average returns than the market portfolio over the 97 rolling one-year holding periods included in the study. The strategies have a higher standard deviation of returns across the 97 start months, but are less likely than the market portfolio to experience negative returns over any three or five-year time period. Overall, the best performing strategies are EBIT to enterprise value and return on capital, EBIT to enterprise value alone, and earnings yield (the inverse of the P/E ratio). Adding a profitability factor to form a GARP strategy from a simple one-factor value strategy does not appear boost performance, though it does reduce risk in the EBIT to enterprise value and return on capital strategy. My results indicate that individual investors who are able to tolerate occasional underperformance should consider using a GARP or value strategy in at least a portion of the portion of their portfolio that is allocated to U.S. equities.

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The Effect of Environmental Disclosure and Performance on Profitability in the Companies Listed on the Stock Exchange of Thailand (SET)

Jurnal Ilmu Lingkungan ◽

10.14710/jil.19.1.66-72 ◽

2021 ◽

Vol 19 (1) ◽

pp. 66-72

Author(s):

Indah Fajarini Sri Wahyuningrum ◽

Muhammad Ihlashul Amal ◽

Suci Sularsih

Keyword(s):

Environmental Performance ◽

Stock Exchange ◽

Linear Regression Analysis ◽

Multiple Linear Regression Analysis ◽

Iso 14001 ◽

Company Size ◽

Analysis Tool ◽

Environmental Disclosure ◽

Time Period ◽

One Year

The main objective of this study is to determine the empirical evidence of the effect of environmental disclosure, environmental performance, company age, and company size on profitability. The purposive sampling method was used to determine the sample of companies and obtained 85 companies from a total population of 100 large companies listed on the Thailand Stock Exchange (SET) in 2018. The data analysis technique used was multiple linear regression analysis using analysis tool IBM SPSS Statistics version 26. The results of this study prove that environmental disclosure has a significant positive effect on profitability. Environmental performance and company size have a significant negative effect on profitability. On the other hand, company age is not proven to have a significant effect on profitability. Based on the research results, it can be concluded that more extensive environmental disclosure is able to increase the achievement of profitability. However, company age is not a factor affecting profitability. Meanwhile, company size and environmental performance as measured by total assets and the existence of ISO 14001 certifications are proven to reduce the level of company profitability. This study also has several limitations, including the time period which is limited to only one time period, namely 2018. It is expected that further studies can expand the time period by more than one year. This is since using a time period of more than one year can illustrate the effect of environmental disclosure and environmental performance, company age and company size on the profitability achieved by the companies. In addition, it is expected that the results of this study can provide input to companies to be more concerned regarding company performance activities, especially on the environment because there are still many companies that have low levels of environmental disclosure even though environmental disclosure in Thailand is still voluntary.

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Sexual maturation in Atlantic salmon male parr may be triggered both in early spring and late summer under standard farming conditions

10.1101/2021.03.29.437499 ◽

2021 ◽

Author(s):

Elia Ciani ◽

Kristine von Krogh ◽

Rasoul Nourizadeh-Lillabadi ◽

Ian Mayer ◽

Romain Fontaine ◽

...

Keyword(s):

Atlantic Salmon ◽

Sexual Maturation ◽

Late Summer ◽

Early Spring ◽

Plasma Testosterone ◽

Farmed Salmon ◽

Early Maturing ◽

Advanced Stages ◽

One Year ◽

Immature Fish

AbstractMale Atlantic salmon (Salmo salar) display different sexual strategies, maturing either as parr during the freshwater phase (as sneaky spawners), or as post smolts following one or several years at sea. First sexual maturation (puberty) occurs at different times depending on environmental and genetic factors. To improve our knowledge on the timing (age and season) of first sexual maturation in Atlantic salmon male parr, we investigated pubertal activation in second generation farmed salmon from the Norwegian river Figgjo, reared under natural conditions of photoperiod and water temperature. Histological analysis, in combination with morphometric measurements, plasma androgen levels and pituitary gonadotropin gene expression analysis revealed that, as previously reported, some male parr initiated early sexual maturation in spring at one year of age. Interestingly, some male parr were observed to initiate sexual maturation already in autumn, six months after hatching (under-yearlings), much earlier than reported in previous studies. One-year old maturing males showed a low induction in gonadotropin levels, while under-yearling maturing males displayed a significant increase in fshb transcripts as compared to immature fish. Plasma testosterone, detectable also in immature males, increased constantly during testes development, while 11-ketotestosterone, undetectable in immature and early maturing males, increased during more advanced stages of maturation. A mild feminization of the testes (ovotestes) was detected in a subset of samples. This study brings new knowledge on the little investigated field of sexually maturing under-yearlings in Atlantic salmon. This is also the first study comparing the physiology of under-yearling vs one-year old maturing male parr, thus bringing new insights to the remarkable plasticity of Atlantic salmon puberty.

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Neglecting Decline: Remembered and Predicted Personal Development Diverge from Actual Longitudinal Change.

10.31234/osf.io/43qvh ◽

2019 ◽

Author(s):

Sarah Molouki ◽

Daniel Bartels ◽

Oleg Urminsky

Keyword(s):

Longitudinal Study ◽

Personal Development ◽

Absolute Magnitude ◽

Longitudinal Change ◽

Personal Change ◽

Future Change ◽

Change Over Time ◽

Time Period ◽

One Year ◽

Over Time

A one-year longitudinal study was conducted to investigate the accuracy of people’s assessmentsof their own personal change over time. We compared people’s predicted, actual, and recalledchange in their personality, values, and preferences over this time period. On average,participants underestimated the absolute magnitude of their personal change, yet simultaneouslyoverestimated their net improvement, in both prediction and recall. This effect was due to anasymmetry whereby people selectively neglected negative changes, especially prospectively.Although participants in our sample both improved and declined over the year, they were morelikely to remember past improvements than declines, and made nearly uniformly positivepredictions of future change. We discuss how the current findings reconcile researchdemonstrating expectations of personal improvement (e.g., Wilson & Ross, 2001; Kanten &Teigen, 2008) with other research that suggests people overpredict their personal stability(Quoidbach, Gilbert, & Wilson, 2013).

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Adolescent friendships predict later resilient functioning across psychosocial domains in a healthy community cohort

10.31219/osf.io/ysd7p ◽

2016 ◽

Author(s):

Anne-Laura Van Harmelen

Keyword(s):

Family Support ◽

Psychosocial Functioning ◽

Principal Component ◽

Mental Wellbeing ◽

Psychiatric Symptomatology ◽

Family Experiences ◽

Time Period ◽

One Year ◽

Healthy Community ◽

The Relationship

Background: Adolescence is a key time period for the emergence of psychosocial and mental healthdifficulties. To promote adolescent adaptive (‘resilient’) psychosocial functioning, appropriate conceptualizationand quantification of such functioning and its predictors is a crucial first step. Here,we quantify resilient functioning as the degree to which an individual functions better or worse thanexpected given their self-reported childhood family experiences, and relate this to adolescent familyand friendship support.Method: We used Principal Component and regression analyses to investigate the relationship betweenchildhood family experiences and psychosocial functioning (PSF: psychiatric symptomatology,personality traits and mental wellbeing) in healthy adolescents (the Neuroscience in Psychiatry Network;N=2389; ages 14-24). Residuals from the relation between childhood family experiences andPSF reflect resilient functioning; the degree to which an individual is functioning better, or worse,than expected given their childhood family experiences. Next, we relate family and friendship supportwith resilient functioning both cross-sectionally and one year later.Results: Friendship and family support were positive predictors of immediate resilient psychosocialfunctioning, with friendship support being the strongest predictor. However, whereas friendshipsupport was a significant positive predictor of later resilient functioning, family support had a negativerelationship with later resilient psychosocial functioning.Conclusions: We show that friendship support, but not family support, is an important positive predictorof both immediate and later resilient psychosocial functioning in adolescence and early adulthood.Interventions that promote the skills needed to acquire and sustain adolescent friendshipsmay be crucial in increasing adolescent resilient psychosocial functioning.

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Indian Press Coverage of Farmers’ Suicides in Andhra Pradesh: A Content Analysis

IRA-International Journal of Management & Social Sciences (ISSN 2455-2267) ◽

10.21013/jmss.v14.n2.p3 ◽

2019 ◽

Vol 14 (2) ◽

pp. 47

Author(s):

J. Madhu Babu ◽

S. Raja Rao

Keyword(s):

Content Analysis ◽

Andhra Pradesh ◽

World Population ◽

Chi Square ◽

Time Period ◽

Farmer Suicides ◽

Cotton Seeds ◽

The Government ◽

One Year ◽

Sample Method

<p>India, consisting of 16 percent of world population subsists only on 2.4 percent land resources. Agriculture is the only source of livelihood to the two third of the population which gives employment to 57 percent of the workforce. Agriculture in India is often regarded as gambling with monsoons, because of its almost exclusive dependency on precipitation from monsoons. The failure of monsoons leading to a series of droughts, lack of better prices, exploitation by middlemen, and Gene Modified (GM) seed companies who are selling expensive cotton seeds and fertilizers, all of which have led to a series of suicides committed by farmers across India. Farmers' suicides are a complex phenomenon. Since the 1990s farmer suicides in India have made headlines. The journalist Palagummi Sainath highlighted that 17,500 farmers were suicides between 2002 to 2006. The government figures show 14,000 farmers took their own lives in 2011. The total number of farmers’ suicides crossed 3 lakh mark till in 2014. That most suicides occurred in the states of Andhra Pradesh, Maharashtra, Karnataka, Kerala and Punjab. This study seeks to investigate news items on farmers’ suicides in the Indian newspapers. A quantitative content analysis was adopted in this research. This study used two English dailies i.e. The Hindu and The New Indian Express and two Telugu dailies i.e. Eenadu and Andhrajyothi were taken for analysis. It is not a random sample. In this, a purposive sample method was adopted. The selection time period was one year i.e. from January 1, 2015, to December 31, 2015. Keeping in view ten subject categories have been mainly identified for this research. All the data collected were analyzed simple percentage and mean, standard deviation, ANOVA, Chi-square have been used for analysis. </p>

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Coverage of Government and Judiciary Relationship: A Study of Urdu and English Newspapers of Pakistan

FWU Journal of Social Sciences ◽

10.51709/fw127211 ◽

2020 ◽

Vol 14 (4) ◽

pp. 131-139

Author(s):

Behramand Durrani ◽

◽

Riffat Alam

Keyword(s):

Content Analysis ◽

Supreme Court ◽

Research Study ◽

Government Performance ◽

Time Period ◽

The Media ◽

The Government ◽

One Year ◽

The One ◽

National Reconciliation

This present study analyzes the role played by the media during the controversy between Government of Pakistan and its Supreme Court in 2012. This study is particularly focused on the issues pertinent to the National Reconciliation Ordinance (NRO) case. It employed content analysis as research study and quantitatively examined the columns in the Pakistani newspapers; including, Dawn and Daily Jang for the one year time period in the year 2012. A conflicting relationship has been found between the government and judiciary concerning the National reconciliation ordinance (NRO). It was concluded that Dawn and Daily Jang, both newspapers, follow the same agenda about the NRO issue as both of these newspapers offered negative coverage of this issue. Compared to Jang, Dawn was more inclined to the negative framing of judiciary, and Jang was inclined to the negative reporting of government performance. Hence, the Pakistani Print media has framed the issues negatively between the government and the judiciary. Frequent negative slants were observed in Urdu newspaper as compared to English newspaper.

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