scholarly journals Replacement of Chemical Components in Energy Drinks Using Biological Alternatives

2021 ◽  
Vol 9 (VI) ◽  
pp. 655-661
Author(s):  
Guruprasad Bhandwale
Keyword(s):  
Chemical Compounds ◽  
Energy Drinks ◽  
Herbal Extract ◽  
Chemical Components ◽  
Vitamin B ◽  
Herbal Extracts ◽  
Good Source ◽  
Lemon Grass ◽  
Excess Amount ◽  
Human Disorders

Energy drinks are widely used all over the world as an energy booster or stimulant It contains chemicals like caffeine, taurine, excess amount of Vitamin B, ginseng, and sugar which cause different human disorders when consumed on regular basis. Herbs are types of plants with redolent or aromatic properties herbs are used to savor food and are also used in medicines. Herbal compounds are a good source of several nutrient elements essential for the metabolic process. Herbs have wide applications in energy drinks. Herbs like lemon Grass, mint, rosemary, Ashwagandha are used significantly. The current study proposes a way to replace chemical compounds in energy drinks with herbal extract. Natural herbal extracts like rosavin, rosarian, phenols are extracted other properties like the texture of the drink, color, pH, taste, odour were also monitored.

Determination of Bioactive Components of 60°С Volatiles from Cinnamomum camphora Branches by TD-GC/MS

2011 ◽  
Vol 230-232 ◽  
pp. 852-856
Author(s):  
Qing Li ◽  
Dang Quan Zhang ◽  
Qi Mei Liu ◽  
Kuan Peng
Keyword(s):  
Chemical Compounds ◽  
Chemical Components ◽  
Cinnamomum Camphora ◽  
Bioactive Components ◽  
Industrial Materials ◽  
Analytical Result ◽  
Main Components

The chemical components of helium volatiles from the fresh branches of Cinnamomum camphora were studied by TD-GC/MS. The analytical result by 60°С-based TD-GC/MS showed that 55 peaks were obtained from the helium volatiles from the fresh branches of Cinnamomum camphora and 53 chemical compounds were identified. The results showed that the main components were as: Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1R)- (15.4328%), 1,3-Benzodioxole, 5-(2-propenyl)- (14.881%), Tricyclo[2.2.1.0(2,6)]heptane, 1,7-dimethyl-7-(4-methyl-3-pentenyl)-, (-)- (12.694%), p-menth-1-en-8-ol (9.832%), Bicyclo[2.2.1]heptane, 2-methyl-3-methylene-2-(4-methyl-3- pentenyl)-, (1S-exo)- (6.143%), 1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl- (5.365%), Bicyclo[3.1.1] hept-2-ene, 2,6-dimethyl-6-(4-methyl-3-pentenyl)- (4.527%), Naphthalene, 1,2,3,5,6,8a- hexahydro-4,7-dimethyl-1-(1-methylethyl)-, (1S-cis)- (4.129%), 3-Cyclohexen-1-ol, 4-methyl-1- (1-methylethyl)- (2.965%), Borneol (2.627%), Bicyclo[2.2.1]heptan-2-ol, 1,7,7-trimethyl-, acetate, (1S-endo)- (2.586%), Copaene (2.534%), 1,6,10-Dodecatriene, 7,11-dimethyl-3-methylene-, (Z)- (1.612%), (-)-Isosativene (1.121%), etc. The analytical result suggested that the helium volatiles from the fresh branches of Cinnamomum camphora could be used as industrial materials of biomedicines and spicery.

scholarly journals Quercetin Potentiates the NGF-Induced Effects in Cultured PC 12 Cells: Identification by HerboChips Showing a Binding with NGF

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Gallant K. L. Chan ◽  
Winnie W. H. Hu ◽  
Zoey X. Zheng ◽  
M. Huang ◽  
Yan X. Y. Lin ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Drug Development ◽  
Ginkgo Biloba ◽  
Water Extract ◽  
Herbal Extract ◽  
Herbal Extracts ◽  
Mental Processes ◽  
Pc 12 Cells ◽  
Excellent Source

Dementia is a persistent disorder of the mental processes and is strongly related to depression. However, the performance of current antidepression medicine is far from satisfactory. Herbal extract provides an excellent source to identify compounds for possible drug development against depression. Here, HerboChips were employed to search herbal compounds that could bind nerve growth factor (NGF). By screening over 500 types of herbal extracts, the water extract of Ginkgo Folium, the leaf of Ginkgo biloba, showed a strong binding to NGF. The herbal fractions showing NGF binding were further isolated and enriched. By using LC-MS/MS analysis, one of the NGF binding fractions was enriched, which was further identified as quercetin, a major flavonoid in Ginkgo Folium. Quercetin, similar to Ginkgo Folium extract, could enhance the effect of NGF in cultured PC 12 cells, including potentiation of neurite outgrowth and phosphorylation of Erk-1/2. This is the first report of discovering an NGF binding compound by using HerboChips from herbal extracts, which could be further developed for antidepression application.

Adding herbal extracts to silicone gel on post-sternotomy scar: a prospective randomised double-blind study

2020 ◽  
Vol 29 (Sup4) ◽  
pp. S36-S42
Author(s):  
Palakorn Surakunprapha ◽  
Kengkart Winaikosol ◽  
Bowornsilp Chowchuen ◽  
Kriangsak Jenwitheesuk ◽  
Kamonwan Jenwitheesuk
Keyword(s):  
Aloe Vera ◽  
Median Sternotomy ◽  
Centella Asiatica ◽  
Herbal Extract ◽  
Double Blind Study ◽  
Herbal Extracts ◽  
Double Blind ◽  
Silicone Gel ◽  
Group 2 ◽  
Group 1

Objective: Silicone gel has been shown effective in improving healing post-sternotomy scars. It remains to be determined whether adding herbal extracts to the gel would augment the healing effect. Method: After median sternotomy, patients were randomised into two groups. Group 1: topical silicone gel plus herbal extract gel (Allium cepa, Centella Asiatica, Aloe vera and Paper Mulberry) and Group 2: silicone gel. Patients were treated for six months. The postoperative scars were assessed at three and six months by plastic surgeons using the Vancouver Scar Scale (VSS) and the patient assessment scar scale. Results: Each group comprised 23 patients (n=46 in total). The VSS was significantly lower in Group 1 than in Group 2 (p=0.018 and p=0.051, respectively). In Group 1, the four differences from baseline were vascularity scores at three and six months (–0.391, p=0.025; –0.435, p=0.013, respectively), and pigmentation scores at three and six months (–0.391, p=0.019; –0.609, p=0.000, respectively). In Group 2, differences from baseline were the pigmentation and vascularity score at six months (–0.6609, p=0.000; –0.348, p=0.046, respectively). Conclusion: Our results suggest, post-sternotomy scars trend to have better vascularity and pigmentation when treated with silicone gel plus herbal extracts.

scholarly journals GC-MS Chemical Characterization of Main Components of Smilax Domingensis Wild. in Cuba

2018 ◽  
Vol 5 (4) ◽  
pp. 79 ◽  
Author(s):  
Pilar A. Soledispa ◽  
José González ◽  
Armando Cuéllar ◽  
Julio Pérez ◽  
Max Monan
Keyword(s):  
Mass Spectra ◽  
Chemical Constituents ◽  
Chemical Characterization ◽  
Ethanolic Extract ◽  
Chemical Compounds ◽  
Chemical Components ◽  
Analytical Technique ◽  
Main Components ◽  
First Time

A preliminary chemical characterization of main components of ethanolic extract with dried rhizomes of Smilax domingensis Wid. that grow in Cuba was done using a GCMS-QP2010 Ultra Shimadzu and the mass spectra of the compounds found in the extract was matched with the National Institute of Standards and Technology (NIST) library. After sample derivatization 125 chemical compounds were registered by the equipment and from them, 35 different chemical components were characterized and reported for the first time from this part of the plant in our country. The results demonstrate the developed method could be employed as a rapid and versatile analytical technique for identification of chemical constituents and quality control of Smilax domingensis.

scholarly journals A New Strategy for Quality Evaluation and Identification of Representative Chemical Components in Polygonum multiflorum Thunb.

2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Yun-xia Li ◽  
Xiao-hong Gong ◽  
Mei-chen Liu ◽  
Cheng Peng ◽  
Peng Li ◽  
...  
Keyword(s):  
Quality Evaluation ◽  
Comprehensive Evaluation ◽  
Principal Component ◽  
Chemical Compounds ◽  
Chemical Components ◽  
Health Food ◽  
Polygonum Multiflorum ◽  
New Strategy ◽  
Novel Method

Polygonum multiflorum Thunb. (HSW) is widely used as herb medicine and health food additive. Recently, a series of HSW-induced hepatotoxicities have been reported and many studies have been carried out to investigate it. But contradictory conclusions were drawn that might be caused by the inconsistent quality of market decoction pieces. Therefore, the HSW decoction pieces quality was evaluated with a developed novel method in the paper. 25 batches of raw HSW (RHSW) and 21 batches of processed HSW (PHSW) samples were purchased from different provinces of China. HPLC determination was performed to identify and detect the contents of 16 chemical compounds in herbal material. Fingerprint similarity was analyzed using chromatography information and the results showed that most herbs were in good similarity. Then, a comprehensive evaluation strategy based on principal component analysis with representative quality control indicators was developed to evaluate the quality of HSW samples. And the rationality of the developed method was verified by HCA analysis. The results showed that the herb from Dabashan, Sichuan Province, no matter RHSW or PHSW had the best quality. Different representative components were selected for RHSW or PHSW decoction pieces which might be caused by the chemical reaction during processing. And most PHSW were unqualified according to the requirement of Chinese Pharmacopeia which might take the responsibility for the toxicity of HSW.

Differences in Chemical Component and Anticancer Activity of Green and Ripe Forsythiae Fructus

2017 ◽  
Vol 45 (07) ◽  
pp. 1513-1536 ◽  
Author(s):  
Jiaolin Bao ◽  
Ren-Bo Ding ◽  
Yeer Liang ◽  
Fang Liu ◽  
Kai Wang ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Principal Component ◽  
Chemical Compounds ◽  
Clinical Applications ◽  
Chemical Components ◽  
Aqueous Extracts ◽  
Clear Separation ◽  
Marker Compounds

Forsythiae Fructus, Lianqiao in Chinese, is one of the most fundamental herbs in Traditional Chinese Medicine. Both green Forsythia (GF) and ripe Forsythia (RF) are referred to Forsythiae Fructus in medicinal applications. In most cases, they are used without distinction. In this study, a metabolomics approach was performed to compare componential differences of two Forsythiae Fructus aqueous extracts subtypes. Principal component analysis (PCA) score plots from the UPLC-MS data showed clear separation between the two subtypes, indicating there are significant differences in the chemical components between GF and RF. Meanwhile, the anticancer activity of them was also compared. GF exhibited much stronger antitumor activity than RF against B16-F10 murine melanoma both in vitro and in vivo. 15 chemical compounds were identified as specific markers for distinguishing GF and RF. Among these marker compounds, forsythoside I, forsythoside A, forsythoside E and pinoresinol were demonstrated to be key important active compounds that account for the different anticancer efficacies of GF and RF. Our data suggest that GF and RF should be distinctively used in clinical applications, particularly in the anticancer formulas, in which GF should be preferentially prescribed.

scholarly journals Antimalarial Effects of Iranian Flora Artemisia sieberi on Plasmodium berghei In Vivo in Mice and Phytochemistry Analysis of Its Herbal Extracts

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Hossein Nahrevanian ◽  
Bayram Sheykhkanlooye Milan ◽  
Masoud Kazemi ◽  
Reza Hajhosseini ◽  
Soudeh Soleymani Mashhadi ◽  
...  
Keyword(s):  
Plasmodium Berghei ◽  
Room Temperature ◽  
Herbal Extract ◽  
Study Group ◽  
Herbal Extracts ◽  
High Concentration ◽  
Flowering Stage ◽  
Aerial Parts ◽  
Artemisia Sieberi

The aim of this study is pharmacochemistry of Iranian flora Artemisia sieberi and its antimalarial effects on Plasmodium berghei in vivo. This is the first application of A. sieberi for treatment of murine malaria. A. sieberi were collected at flowering stage from the Khorassan and Semnan provinces of Iran; the aerial parts were air-dried at room temperature and then powdered. The powder was macerated in methanol, filtered with Bokhner hopper and solvent was separated in rotary evaporator. Total herbal extract was subsequently processed for ether and chloroform extracts preparation. The toxicity of herbal extract was assessed on naive NMRI mice with high, average and low doses; then pathophysiological signs were assessed. Finally, the antimalarial efficacy was investigated on two groups of Plasmodium berghei infected mice. Percentage of parasitaemia and pathophysiology were also evaluated. The results of this assessment showed no toxicity even by high concentration of herbal extract. A significant reduction in percentage of parasitaemia was observed; no alterations of hepatosplenomegaly and body weight were indicated in study group. A. sieberi extracts showed antimalarial effects against murine malaria with some efficacies on reducing pathophysiology. However, there is requirement to find the major component of this herbal extract by further studies.

Deep Analysis on Bioindustry Prospects of 40°С Volatiles of Cinnamomum camphora Branches

2011 ◽  
Vol 480-481 ◽  
pp. 266-271
Author(s):  
Qi Mei Liu ◽  
Dang Quan Zhang ◽  
Kuan Peng ◽  
Wan Xi Peng
Keyword(s):  
Acetic Acid ◽  
Ethyl Ester ◽  
Chemical Compounds ◽  
Chemical Components ◽  
Cinnamomum Camphora ◽  
Propenoic Acid ◽  
Long Time ◽  
Industrial Materials ◽  
Analytical Result ◽  
Main Components

Cinnamomum camphora has been used to heal some specific diseases in the Chinese Folk for a long time. In order to explore the wide utilization in biomedicine and spicery, the chemical components of helium volatiles from the fresh branches of C. camphora were studied by TD-GC/MS. The analytical result by TD-GC/MS showed that 50 peaks were obtained from the helium volatiles from the fresh branches of C. camphora and 46 chemical compounds representing 99.993% of the total areas were identified. The results showed that the main components were as: Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1R)- (9.620%), 3-Cyclohexene-1- methanol, .alpha.,.alpha.4-trimethyl- (9.425%), 1,3-Benzodioxole, 5-(2-propenyl)- (8.223%), Bicyclo[2.2.1]heptane, 2-methyl-3-methylene-2-(4-methyl-3-pentenyl)-, (1S-exo)- (7.541%), Tricyclo[2.2.1.0(2,6)]heptane, 1,7-dimethyl-7-(4-methyl-3-pentenyl)-, (-)- (6.884%), Bicyclo[3.1.1] hept-2-ene, 2,6-dimethyl-6-(4-methyl-3-pentenyl)- (6.050%), Bicyclo[2.2.1]heptan-2-one, 1,7,7- trimethyl-, (1S)- (4.678%), 1,3-Benzodioxole, 5-(2-propenyl)- (4.500%), Naphthalene, 1,2,3,5,6,8a- hexahydro-4,7-dimethyl-1-(1-methylethyl)-, (1S-cis)- (4.491%), 3-Cyclohexen-1-ol, 4-methyl-1- (1-methylethyl)-, (R)- (4.254%), Copaene (4.120%), Tricyclo[2.2.1.0(2,6)]heptane, 1,7-dimethyl-7- (4-methyl-3-pentenyl)-, (-)- (4.097%), Acetic acid, 1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl ester (3.574%), Borneol 3.334%), 3-(4-N,N-Dimethylaminophenyl)propenoic acid, 2- (diethoxyphosphinyl)-, ethyl ester (2.809%), Eucalyptol (2.096%), 1,6,10-Dodecatriene, 7,11- dimethyl-3-methylene-, (Z)- (1.885%), (-)-Isosativene (1.664%), 1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl- (1.407%), Cyclohexene, 1-methyl-4-(5-methyl-1-methylene-4-hexenyl)-, (S)- (1.218%), 1,4-Methanoazulene, decahydro-4,8,8-trimethyl-9-methylene-, [1S-(1.alpha.,3a.beta., 4.alpha.,8a.beta.)]- (1.174%), .alpha.-Caryophyllene (1.156%), etc. The analytical result suggested that the helium volatiles from the fresh branches of C. camphora can be applicable to biomedicine and spicery industrial materials.

scholarly journals ANALYSIS OF CHEMICAL COMPOUNDS OF AGARWOOD OIL FROM DIFFERENT SPECIES BY GAS CHROMATOGRAPHY MASS SPECTROMETRY (GCMS)

2014 ◽  
Vol 15 (1) ◽  
Author(s):  
Yumi Zuhanis Has-Yun Hashim ◽  
Nur Izzah Ismail ◽  
Phirdaous Abbas
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Chemical Compounds ◽  
Gas Chromatography Mass Spectrometry ◽  
Chemical Components ◽  
Chromatography Mass Spectrometry ◽  
Three Samples ◽  
Pleasant Odour ◽  
Agarwood Resin ◽  
Agarwood Oil

ABSTRACT: Agarwood oil is a highly prized type of oil due to its unique aroma. The oil is extracted from the fragrant resin found in the agarwood tree (trunk).  The unique aroma and quality of agarwood resin and oil are contributed by the presence of certain chemical compounds. In this work, analysis and comparison of the chemical compounds of agarwood oil from A. malaccensis, A. sub-integra and a mixture of both were conducted.  The essential oils were diluted in hexane (5%) prior to gas chromatography mass spectrometry (GCMS) analysis performed using Agilent GCMS 7890A coupled with MSD quadrupole detector 5975 C.  Separation of analytes by gas chromatography was carried out using a Hewlett Packard HP-5MS silica capillary column (30 m X 0.25 mm X 0.25 mm). A total of 107 compounds were identified from the three samples of agarwood oils. Fifty-five (55) components were identified in A. malaccensis sample which contributes to the largest portion of the total compounds. About 20% of the compounds identified were aromatic and sesquiterpenes which have been revealed to be the main active compounds of agarwood oils which also give the aroma and pleasant odour of agarwood. Different compositions or profile of chemical components were found in agarwood oils from the two different species. Two compounds were commonly identified in all three samples namely 3-phenyl-2-butanone and alpha-cubebene.  Further studies are needed to refine the results which later can be used to assist detection and authentication of agarwood as well as its scientific-based grading. ABSTRAK: Minyak gaharu merupakan sejenis minyak beraroma unik yang mendapat permintaan tinggi dan mahal. Minyak ini diekstrak daripada resin beraroma yang terbentuk di dalam batang pokok gaharu. Keunikan aroma dan kualiti resin dan minyak gaharu ini bergantung kepada kehadiran bahan kimia tertentu. Penyelidikan ini menjurus kepada analisis dan perbandingan bahan-bahan kimia yang terdapat dalam minyak gaharu daripada spesis A. malaccensis, A. sub-integra dan campuran kedua-duanya. Minyak gaharu dilarutkan di dalam 5% heksana sebelum dianalisis menggunakan kromatografi gas Agilent GCMS 7890A berserta spektormetri jisim (MSD quadrupole detector 5975 C). Kolum kapilari silika Hewlet Packard HP-5MS (30 m X 0.25 mm X 0.25 mm) digunakan untuk pemisahan bahan-bahan kimia tersebut. Sejumlah 107 kompaun dikenalpasti dalam ketiga-tiga sampel minyak gaharu tersebut dengan 55 kompaun didapati di dalam sample A. malaccensis. Ini merupakan bahagian terbesar daripada keseluruhan kompaun. Sebanyak 20 % daripada keseluruhan kompaun yang dikenalpasti adalah daripada kumpulan seskuiterpena dan bersifat aromatik, juga merupakan kumpulan yang bertanggungjawab memberi aroma yang unik kepada minyak gaharu. Setiap spesis didapati mempunyai komposisi atau profil bahan kimia yang tersendiri. Dua kompaun iaitu 3-phenyl-2-butanone dan alpha-cubebene ditemui dalam ketiga-tiga sample yang dianalisis. Kajian lanjut adalah perlu untuk memurnikan dapatan hasil penyelidikan yang berpotensi bagi membantu pengenalpastian gaharu berserta pembangunan penggredan gaharu yang lebih saintifik.

scholarly journals Chemical Composition of Melaleuca Cajuputi Powell

2019 ◽  
Vol 9 (1) ◽  
pp. 3479-3483 ◽  
Keyword(s):  
Chemical Composition ◽  
Essential Oil ◽  
Chemical Compound ◽  
Steam Distillation ◽  
Chemical Compounds ◽  
Chemical Components ◽  
Melaleuca Cajuputi ◽  
Anti Inflammatory

Essential oil extracted from Melaleucagenus has been widely used worldwidefor many purposes. Most of the its has been reported as the source of phytochemical compound where mostly have anti-inflammatory, antiulcer, antioxidant, antimicrobial and insecticide properties. Thus, three objectives that have been highlighted in this study are (1) to extract essential oil (cajuput oil) from fresh leaves of MelaleucacajuputiPowell using simple steam distillation,(2) to determine the chemical components of MelaleucacajuputPowell essential oil using GCMS and (3) to compare the chemical compound and its percentage with the previous study.Results found that there were 41 chemical compounds that have been identified. The chemical compounds were monoterpenes such as α-terpinolene, α-pinene, sabinene, 4-terpineol and γ-terpinene. The highest chemical compounds found were caryophyllene (20.16%), α-terpinolene (17.0%),α-humulene (11.91%), βelemene (7.62%) and γ-terpinene (5.62%). In previous research, 1,8-cineole chemical compound was foundhowever, in this study a different chemical compound found, it was caryophyllene, this is due to different geographic area.As a conclusion, most of the compounds found was aromatic, antibacterial andinsecticide properties.

Sign in / Sign up

Export Citation Format

Share Document