scholarly journals Commiphora wightii (Arn.) Bhandari. Review of Its Botany, Medicinal Uses, Pharmacological Activities and Phytochemistry

2019 ◽  
Vol 9 (4-s) ◽  
pp. 613-621 ◽  
Author(s):  
Manisha Bhardwaj ◽  
Aparna Alia

The oldest remedies identified to mankind are herbal medicines. India is recognized worldwide for its Ayurvedic treatment. As only little studies are done on this plant, the purpose of current review is to make accessible up-to-date information on, botany, morphology, ecological biodiversity, medicinal uses, phytochemistry and pharmacological activities on diverse parts of Commiphora wightii (Arn.) Bhandari (C. wightii). This review was assembled using scientific literature from electronic search engine such as Springerlink, BioMed Central, PubMed, Scopus, ScienceDirect, Scielo, Medline and Science domain. Supplementary literatures were obtained from books, book chapters, dissertations, websites and other scientific publications. C. wightii  (Syn. Commiphora mukul Hook. ex. Stocks) or Guggulu tree. C. wightii is a shrub or small tree belonging to Burseraceae family. C. wightii contains volatile oil, gum resin, gugulipids, guggulsterones, guggulsterols, mukolol and other steroids. Guggulu is very much used in Ayuvedic system of medicine as astringent, anti-septic, expectorant, aphrodisiac, carminative, anti-spasmodic, emmenagogue. In Ayurveda, it is the best among herbs that are used for Medoroga and Vata disorders. It is widely used for obesity and it is also known as fat burning agent all over the world. It helps to lower cholesterol and triglycerides level. It is very effective in rheumatoid arthritis, gout and sciatica. It is also one of the most important Rasayana of Ayurveda. In addition it treats sluggish liver, stimulates libido, nervous diseases, bronchial congestion, cardiac and circulatory problems, weak digestion, wounds, abscess, foetid ear, fractures, gynaecological problems and various skin diseases. C. wightii is a very important and trustworthy herb in Ayurvedic medicine. This alternative system of medicine is gaining increasing fame universal. There is a required to isolate active constituents, their biological test, molecular mechanisms, experimental defense and legalization of therapeutic uses of C. wightii. The collected information will be obliging to locate up study protocol for current drugs and Ayurvedic formulation extension in remedial and luxury a variety of ailments.   

Author(s):  
Miss. Chole Laxmi Jalindar

Abstract: The intention of current review is to make available upto-date information on morphology, ecological biodiversity, medicinal uses, phytochemistry and pharmacological activities on different parts of Euphorbia tirucalli (E. tirucalli). This plant has a number of medicinal uses. Latex of E. tirucalli is vesicant and rubefacient which is used for rheumatism, warts, cough, asthma, ear-ache, tooth-ache and neuralgia. It acts as a purgative in small doses while in big doses it is bitter irritant and emetic. Milky juice is alexiteric, carminative and purgative. It is useful in whooping cough is used in treatment of piles. gonorrhea, asthma, leprosy, dropsy, dyspepsia, enlargement of spleen, colic, jaundice and stone in bladder. The fresh milky juice is good alternative in syphilis and a good application in neuralgia. A decoction of branches is used in gastralgia and colic. Bark is used in treatment of fractures. Poultices prepared from the stem are useful to repair the broken bones. Boiled root liquid acts as an emetic in cases of snake-bite and for infertility in women. The wood is used for rafters, toys and veneering purposes. It is also useful against leprosy and foot paralysis subsequent to childbirth. E. tirucalli is reported to have euphol, β-sitosterol, euphorbol hexacosonate, cycloeuphordenol, cyclotirucanenol, tirucalicine, tri-methyl ellagic acid, gallic acids, terpenic alcohol. genotoxic/mutagenic, hepatoprotective, insect repellants, immunomodulatory, larvicidal, molluscicidal/ovicidal/piscicidal, myelopoiesis, proteolytic/chitinolytics pharmacological activities. There is a need to isolate dynamic constituents, their biological trial, molecular mechanisms, experimental protection and legalization of therapeutic uses of E. tirucalli. The collected information will be helpful to locate up study protocol for expansion in curative and treat a variety used in treatment of piles., isoeuphorol, taraxasterol, tirucallol, euphorone, euphorcinol, euphorbins, 12-deoxy4βhydroxyphorbol-13-phenyl acetate-20-acetate, 12, 20- dideoxyphorbol-13-isobutyrate, glut-5-en-3-β-ol, 3,3′- diO-methylellagic acid, euphorbin-A (polyphenol), tirucallin-A (7) (tannin), tirucallin-B (11), euphorbin-F (14) (dimers), cycloartenol, 24- methylenecycloartenol, ingenol triacetate, 12-deoxy-4β-hydroxyphorbol- 13- phenyl acetate-20-acetate, taraxerone, euphorginol, taraxerol, campesterol, stigmasterol, palmitic acid, linoleic acid, β-amyrin, etc. Active phytoconstituents. E. tirucalli have possessed activity in humanly mphocytes, analgesic, anthelmintics, antiarthritic, antibacterial/antifungal/antimicrobial Antihemerrhoids. Keywords: Euphorbia tirucalli Morphology Ecological biodiversity Medicinal uses Phytochemistry Anticance antihemerrhoids


2019 ◽  
Vol 9 (5) ◽  
pp. 199-206 ◽  
Author(s):  
Omji Porwal ◽  
Muath Sheet Mohammed Ameen ◽  
Esra T Anwer ◽  
Subasini Uthirapathy ◽  
Javed Ahamad ◽  
...  

The oldest remedies identified to mankind are herbal medicines. India is recognized worldwide for its Ayurvedic treatment. India has rich history of using many plants for medicinal purposes. Remedial plants are cooperating extremely dynamic position in customary drugs for the action of a variety of illness. However a key obstacle, which has hindered the promotion in use of alternative medicines in the developed countries, is no evidence of documentation and absence of stringent quality control measures. There is a demand for the evidence of every investigate effort execute on conventional remedies in the appearance of certification. The purpose of current review is to make accessible up-to-date information on, botany, morphology, ecological biodiversity, therapeutic uses, phytochemistry and pharmacological activities on diverse parts of Silybum marianum (L.) Gaertn (S. marianum). This review was assembled using technical literature from electronic search engine such as Springer link, Bio Med Central, Pub Med, Scopus, Science Direct, Scielo, Medline and Science domain. Supplementary texts were obtained from books, book chapters, dissertations, websites and other scientific publications. S. marianum a member of the Asteraceae family, is a tall herb with large prickly white veined green leaves and a reddish-purple flower that ends in sharp spines. It is native of the Mediterranean region and which has also spread in East Asia, Europe, Australia and America. Confident chemical constituents were exposed cognate as silybin A, silybin B, isosilybin A, isosilybin B, silychristin, silydianin, apigenin 7-O-β-(2″- O-α-rhamnosyl)galacturonide, kaempferol 3-O-α-rhamnoside-7-O-β-galacturonide, apigenin 7-O-β-glucuronide, apigenin 7-O-β-glucoside, apigenin 7-O-β-galactoside, kaempferol-3-O-α-rhamnoside, kaempferol, taxifolin and quercetin. The plant is exclusively used as anti-diabetic, hepatoprotective, hypocholesterolaemic, anti-hypertensive, anti-inflammatory, anti-cancer, and as an anti-oxidant. Seeds of the plant are also used as an anti-spasmodic, neuroprotective, anti-viral, immunomodulant, cardioprotective, demulcent and anti-haemorrhagic. The plant is also serves as a galactagogue, agent that induces milk secretion and used in the treatment of uterine disorders. The plant is employed in dissimilar conventional schemes of remedy in the cure of different illness.


Author(s):  
ALFRED MAROYI

Boscia albitrunca is a medium-sized tree widely used as herbal medicine in Southern Africa. The current study critically reviewed the botany, medicinal uses, phytochemistry, and pharmacological activities of B. albitrunca. Literature on botany, medicinal uses, phytochemical, and biological activities of B. albitrunca was collected from multiple internet sources including Elsevier, Google Scholar, SciFinder, Web of Science, PubMed, BMC, Science Direct, and Scopus. Complementary information was gathered from pre-electronic sources such as books, book chapters, theses, scientific reports, and journal articles obtained from the university library. This study revealed that the species is used as herbal medicine in 75.0% of the countries in Southern Africa where the species is indigenous. The bark, leaves, and roots of B. albitrunca are mainly used as herbal medicines for constipation, epilepsy, hemorrhoids, headache, human immunodeficiency virus/acquired immune deficiency syndrome, skin diseases, syphilis, and as ethnoveterinary medicine. Ethnopharmacological research identified phenolic compounds, alkaloids, coumarins, flavonoids, saponins, steroids, tannins, and triterpernoids from leaves of B. albitrunca. The crude extracts of the species and the compound martynoside isolated from B. albitrunca exhibited antibacterial and antifungal activities. B. albitrunca should be subjected to detailed phytochemical, pharmacological, and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.


2020 ◽  
Vol 10 (5) ◽  
pp. 196-204
Author(s):  
Alfred Maroyi

Gymnanthemum coloratum is a shrub or a small tree widely used as traditional medicine throughout its distributional range in tropical Africa. The current study is aimed at reviewing the phytochemistry, pharmacological properties and medicinal uses of G. coloratum. Literature on pharmacological properties, phytochemistry and medicinal uses of G. coloratum was obtained from numerous internet sources such as Scopus, Elsevier, SciFinder, Google Scholar, Pubmed, ScienceDirect, BMC and Web of Science. Other sources of information included pre-electronic sources such as journal articles, theses, book chapters, books and other scientific publications obtained from the university library. The articles published between 1964 and 2020 were used in this study. The current study showed that G. coloratum is used as an anthelmintic, and traditional medicine for reproductive problems, schistosomiasis, liver diseases, sexually transmitted infections, diabetes, sores and wounds, respiratory problems, malaria, skin diseases, fever and gastro-intestinal problems. Ethnopharmacological research identified glaucolides, lactones, amino acids, essential oils, alkaloids, anthocyanins, cardenolids, coumarins, flavonoids, glycosides, leucoanthocyanins, phenols, quinones, reducing sugars, saponins, steroids, tannins, terpenoids and triterpenes from the aerial parts, leaves, roots and stems of G. coloratum. The aerial parts, leaves, roots and whole plant parts of G. coloratum and compounds isolated from the species exhibited anthelmintic, antimicrobial, anti-Blastocystis, anti-inflammatory, anti-sickling, insecticidal and larvicidal, antiplasmodial, antimalarial, antioxidant, antiproliferative, anti-Toxoplasma, hypoglycaemic and antidiabetic and cytotoxicity activities. Gymnanthemum coloratum should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.


Author(s):  
ALFRED MAROYI

Cussonia paniculata is a small tree widely used as herbal medicine throughout its distributional range in southern Africa. This study is aimed at providing a critical review of the botany, biological activities, phytochemistry, and medicinal uses of C. paniculata. Documented information on the botany, biological activities, medicinal uses, and phytochemistry of C. paniculata was collected from several online sources which included BMC, Scopus, SciFinder, Google Scholar, Science Direct, Elsevier, PubMed, and Web of Science. Additional information on the botany, biological activities, phytochemistry, and medicinal uses of C. paniculata was gathered from pre-electronic sources such as book chapters, books, journal articles, and scientific publications sourced from the University library. This study showed that the bark, fruits, leaves, roots, and stems of C. paniculata are used as emetic, immune booster, and herbal medicine for dysmenorrhea, intestinal parasites and worms, mental problems, boils, shingles and skin diseases, indigestion and stomach complaints, sores, and wounds. Phytochemical compounds identified from the leaves of C. paniculata include acetylated triterpene glycosides, unacetylated triterpene glycosides, flavonoid, steroidal saponin, and triterpenoid saponins. Pharmacological research revealed that C. paniculata extracts have analgesic, antibacterial, anticancer, anti-inflammatory, antiplasmodial, antiprotozoan, Aβ42 protein reduction, and cytotoxicity activities. Future research should focus on evaluating the phytochemical, pharmacological, and toxicological properties of C. paniculata crude extracts as well as compounds isolated from the species.


2018 ◽  
Vol 4 (2) ◽  
pp. 79-85
Author(s):  
Aadil Mustafa ◽  
◽  
Aziz Ahmad ◽  
Aadil Hussain Tantray ◽  
Parvaiz Ahmad Parry ◽  
...  

Dioscorea a well-known source of Diosgenin-steroid raw material, is one of the oldest tuber crop cultivated or harvested from wild in the tropical region throughout the world and make up one of the chief food items for a number of tribal groups. In India there are about 50 species of dioscorea, mainly found in North-East region which is rich in tropical root and tuber crops. Dioscorea produces rhizomes or bulbils, which are having rich medicinal and economic value. The rhizomes are used for the treatment of different diseases like cardiovascular system disorders, central nervous system disorders, disease of bones and joint metabolic disorder, disgestive disorders, sore throat for struma, diarrhea, irritability, abdominal pain, dysfunctional changes in the female reproductive system, skin diseases, oncology and immune deficiency and autoimmune diseases, anti-diabetes, neuroprotectiveused, decrease oxidative stress and many more disordered conditions. Diosgenin is a precursor for the chemical synthesis of drug like steroids and has a great importance for pharmaceutical industry. Dioscorea contains various bioactive chemical substances like diosgenin, corticosterone, and sigmasterol, which are of great market value. The current study is to appraise the medicinal properties, phytochemicals, and pharmacological activities of Dioscorea.


2021 ◽  
Vol 16 (12) ◽  
pp. 150-160
Author(s):  
T. Sharma ◽  
V. Khandelwal

Ever since ancient times, medicinal plants served as a great source of herbal formulations which can confer human civilization with preferential quality of life. Among them, some plants secured their position in mythologies, also highlighting Anthocephalus cadamba, a religious medicinal plant, belonging to the family Rubiaceae, mostly cultivated in tropical regions. Conventional medicinal system of India provides evidences regarding folk medicinal uses for the treatment of various ailments like inflammation, skin diseases, uterine complaints, blood disease and diarrhea etc. Phytochemical investigations revealed the presence of some biologically active compounds like flavonoids, alkaloids, coumarins, terpenoids, diterpenoids, triterpenes, glycosides, sterols, amides and fatty acids and these compounds were found to be accountable for various pharmacological activities such as antimicrobial, antipyretic, anti-inflammatory, analgesic, anticancerous, antidibetic, hypolipidemic, antihepatotoxic, antidiarrhoel, diuretic, laxative, antioxidant, immunomodulatory, wound healing etc.


Author(s):  
ALFRED MAROYI

This study is aimed at providing a critical review of the botany, biological activities and medicinal uses of P. prunelloides. Documented information on botany, biological activities, and medicinal uses of P. prunelloides was collected from several online sources which included BMC, Scopus, SciFinder, Google Scholar, Science Direct, Elsevier, PubMed, and Web of Science. Additional information on the botany, biological activities, and medicinal uses of P. prunelloides was gathered from book chapters, books, journal articles, theses, and scientific publications sourced from the University of Fort Hare Library. The study showed that the leaves and roots of P. prunelloides are used as herbal medicines for bodily pains, burns, cancer, diabetes, fever, gastrointestinal problems, heartburn, heart problems, respiratory problems, retained placenta, rheumatism, sexually transmitted infections, skin infections, snakebite, sores, wounds, toothache, and vomiting. Pharmacological research revealed that P. prunelloides extracts have antibacterial, antimycobacterial, antifungal, antiviral, antidiabetic, anti-inflammatory, analgesic, antioxidant, uterotonic and cytotoxicity activities. Future studies should focus on evaluating the phytochemical, pharmacological, and toxicological activities of P. prunelloides crude extracts as well as chemical compounds isolated from the species.


Author(s):  
SUDHANSHU MISHRA ◽  
RAM SINGH BISHNOI ◽  
RAHUL MAURYA ◽  
DEEPTI JAIN

Herbal medicine has become a medicinal as well as the economic aspect of global significance. While the use of these herbal medicines has increased, there are several questions about their consistency, protection, and effectiveness in different countries. Boswellic acid (BA) is one of the active constituents obtained from plant Boswellia serrata (BS) family Burseraceae. The oleoresin gum of the plant is also known as Salai guggul, Indian olibanum, or Indian frankincense. Boswellia species comprises a variety of phytochemical components, essential oil, BA such as keto-BA, beta-BA, or acetyl keto-BA. This variety of constituents isolated from the plant using various extraction processes such as hydrodistillation, percolation, and ultraviolet-assisted extraction or solvent extraction. The active constituent has different biological activities such as antidiuretic, anticancer, anti-inflammatory, or antitumor activity. This review seeks to update information on plant BS with its medicinal uses, isolation process in the traditional or Indian system of medicine, and justify its use on modern scientific parameters.


Author(s):  
Manish Kapoor ◽  
Gurdeep Kaur ◽  
Navneet Kaur ◽  
Chanchal Sharma ◽  
Kajal Batra ◽  
...  

The genus Hibiscus belongs to the mallow family, Malvaceae comprising of about 275 species growing in tropical and sub tropical areas. The various species of genus Hibiscus have been used as traditional medicine all over the world. There are numerous reports of their traditional medicinal uses in various countries like India, Nigeria, China, and Srilanka etc. to cure various ailments such as hypertension, cardiac diseases, stomach-ache, urine problems, skin diseases and many more. Based on the historical knowledge, various pharmacological and phytochemical studies on some species of the genus Hibiscus have been done. Nevertheless, there are no up-to-date articles published which can provide an overview of pharmacological effects of the genus Hibiscus. Therefore, the main objective of the review article is to provide a systematic comprehensive summary of traditional uses, phytochemistry and pharmacology of the genus Hibiscus and to build up a correlation between its traditional ethano-botanical uses and pharmacological activities so as to find some advanced research opportunities in this field. The given information on the ethano-botanical uses, phytoconstituents and various medicinal properties of the genus Hibiscus was gathered from the online scientific databases through search in Google, Google Scholar, Science Direct, NCBI, Pubmed, Springer Link, Research Gate by using some keywords as. Besides these websites other published literature and unpublished Ph.D. thesis and M.Sc. dissertation were also consulted. Previously conducted research revealed that the genus contains good amount of phytoconstituents such as antioxidants, phytosterols, saponins, lignin, essential oils, glycosides, and anthocyanins etc. Presence of these bioactive compounds in the crude extracts of the plants make it suitable for various medicinal properties like anti inflammatory, anti-diabetic, anti-obesity, anti-proliferative, anti-ulcer, hypersensitive, hypolipidemic, hepatoprotective, nephroprotective and many more. Additionally, this review article showed that mainly two species of the genus i.e. H. rosa-sinensis and H. sabdariffa have been explored for their pharmacological activities. There are few reports on some other species like H. tiliaceous, H. microanthus, H. asper, H. acetosella. This review highlights the medicinal potential of the plant Hibiscus due to its unique blend of phytochemicals. These phytoconstituents can be further assessed and subjected to clinical trials for their proper validations. Although large amount of the data regarding pharmacological effects has already been added to the existing reservoir but still potential of certain species like H. radiatus, H. hirtus, H. moschetous, H. trionum and many more is not yet unveiled and can be considered as future prospects that need to be worked out.  Graphical Abstract: 


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