scholarly journals COVID-19: Animal Epidemiology and Zoonotic risk

2020 ◽  
Author(s):  
Maurizio Ferri ◽  
Shin Jie Yong
Keyword(s):  
Animal Species ◽  
Experimental Studies ◽  
Economic Life ◽  
Emerging Pathogens ◽  
Animal Reservoir ◽  
Susceptible Animal ◽  
Zoonotic Risk ◽  
Epidemic Intelligence ◽  
The One ◽  
Spread Of Infection

The COVID-19 pandemic represents one of the greatest public health crises in recent history that caused unprecedented and massive disruptions of social and economic life globally. It is widely acknowledged that bats are the animal reservoir of coronavirus 2 of the severe acute respiratory syndrome (SARS-CoV-2), the causative agent of the human coronavirus disease 2019 (COVID-19). It has also long been known that coronaviruses circulate among different animal species. However, much remain to be understood of the epidemiology, the presumed existence of intermediate animal species and current and potential animal routes of SARS-Cov-2 transmission to humans. The recent observational and experimental studies also highlight the role of domestic and farmed animals in the epidemiology of COVID-19. This raises concerns of the potential spread of infection among susceptible animal species, with the risk of evolving into panzootic, and the likely occurrence of anthropozoonoses or reverse zoonosis (from humans to animals). As for other wildlife emerging pathogens, the animal-human spillover of SARS-CoV-2 is linked to a closer interface with humans, with the resulting risk of a pandemic. This knowledge has meaningful implications for the design of effective wildlife animal surveillance (epidemic intelligence) targeting CoVs in animal reservoirs, and requires the mobilization of different lines of expertise, notably veterinary epidemiologists and virologists, within a multi-disciplinary approach according to the One-Health principles.

scholarly journals Influenza - flu

2010 ◽  
Vol 64 (1-2) ◽  
pp. 109-125
Author(s):  
Miroslav Valcic ◽  
Sonja Radojicic
Keyword(s):  
Animal Species ◽  
Swine Influenza ◽  
Economic Life ◽  
Front Page ◽  
Swine Flu ◽  
Viral Gene ◽  
Spongiform Encephalopathy ◽  
Human Populations ◽  
Susceptible Animal ◽  
The Past

In epidemiology or in epizootiology, there are some infectious diseases that have potential for significant reduction of the susceptible species population. Over the past few decades, epidemiologists were concentrated on diseases that were 'modern' and made front-page news in tabloids. One should recall diseases like bovine spongiform encephalopathy, SARS and AIDS syndromes. However, we should always be aware of the most dangerous diseases such as our old friend, influenza, or simply, flu. In the past decade, we heard about 'bird' or 'swine' influenza. It is the same disease for different animal species as well as for man. Influenza owes its characteristics to specific virus biology as well as to the epidemiology-epizootiology characteristics of the susceptible species. Antigenic changes that took place thanks to reassortment mechanisms of the viral gene segments cause the onset of the new antigenic combinations of the hemaglutinin and neuraminidase molecules. As a result, new H and/or N antigenic formulas appear for the first time in totally susceptible animal and human populations. That means that in such circumstances, no person in the world is immune to the virus. In that case, such a virus can cause a pandemic with disastrous consequences since influenza is a disease with significant mortality, especially in some segments of the human (as well as animal) population. Birds and swine are virus reservoirs, but these species are at the same time live test tubes in which the virus resides, changes and adapts itself not only to the original species but to other species as well. That means that there is no 'bird' or 'swine' flu. Influenza is an infection of several important animal species as well as man that have potential not only for the reduction of the population size but, in case of the human population, for influencing social and economic life. .

Registration of animal rabies in Krasnodar region

2020 ◽  
pp. 3-4
Author(s):  
Oleg Yu. Chernykh ◽  
◽  
Vadim A. Bobrov ◽  
Sergey N. Zabashta ◽  
Roman A. Krivonos ◽  
...  
Keyword(s):  
Urban Form ◽  
Animal Species ◽  
Farm Animals ◽  
Natural Focus ◽  
Dead End ◽  
Wide Range ◽  
Epizootic Process ◽  
Krasnodar Region ◽  
Spread Of Infection ◽  
Reporting Data

Rabies remains a constant threat to humanity in many parts of the world. At the same time, scientifically grounded antiepizootic measures should be based on the peculiarities of the regional epizootology of this zooanthroponosis. The authors studied the epizootological and statistical reporting data of the Kropotkin Regional Veterinary Laboratory, presented an analysis of the registration of rabies in animals in Krasnodar region. From the obtained data, it should be noted that despite the wide range of animals involved in the epizootic process of rabies infection in Krasnodar region, dogs, cats and foxes play a major role in the reservation and spread of infection, which account for 78.6. Of the total number of registered cases, 15.5% falls on foxes, that indicates the natural focus of the disease, along with the manifestation of the disease in an urban form. At the same time, stray and neglected dogs and cats, which occupy a significant place among the total number of sick animals, are also sources and spread of the infection. Thus farm animals (8.3% of the total number of infected animals) are a biological dead end for the infection. Isolated cases of the disease were noted in muskrat, donkey, raccoon, raccoon dog, marten, ferret and jackal. The authors also established the specific morbidity of various animal species with rabies infection, that is an important aspect in the development and implementation of antiepizootic measures complex

A Relativistic Newtonian Mechanics Predicts with Precision the Results of Recent Neutrino-Velocity Experiments

2014 ◽  
Vol 6 (1) ◽  
pp. 1032-1035 ◽  
Author(s):  
Ramzi Suleiman
Keyword(s):  
Null Hypothesis ◽  
Experimental Studies ◽  
Theoretical Models ◽  
Newtonian Mechanics ◽  
Speed Of Light ◽  
Symmetry Principle ◽  
Proposed Model ◽  
Significant Difference ◽  
The One ◽  
Complete Collapse

The research on quasi-luminal neutrinos has sparked several experimental studies for testing the "speed of light limit" hypothesis. Until today, the overall evidence favors the "null" hypothesis, stating that there is no significant difference between the observed velocities of light and neutrinos. Despite numerous theoretical models proposed to explain the neutrinos behavior, no attempt has been undertaken to predict the experimentally produced results. This paper presents a simple novel extension of Newton's mechanics to the domain of relativistic velocities. For a typical neutrino-velocity experiment, the proposed model is utilized to derive a general expression for . Comparison of the model's prediction with results of six neutrino-velocity experiments, conducted by five collaborations, reveals that the model predicts all the reported results with striking accuracy. Because in the proposed model, the direction of the neutrino flight matters, the model's impressive success in accounting for all the tested data, indicates a complete collapse of the Lorentz symmetry principle in situation involving quasi-luminal particles, moving in two opposite directions. This conclusion is support by previous findings, showing that an identical Sagnac effect to the one documented for radial motion, occurs also in linear motion.

COMPUTATIONAL AND EXPERIMENTAL STUDIES OF A LOW-EMISSION BURNER FOR A PERSPECTIVE TURBOJET ENGINE WITH THE COMPRESSION RATIO EXCEEDING 40

2020 ◽  
Author(s):  
M. A. Danilov ◽  
◽  
M. V. Drobysh ◽  
A. N. Dubovitsky ◽  
F. G. Markov ◽  
...  
Keyword(s):  
Compression Ratio ◽  
Experimental Studies ◽  
The Other ◽  
Aircraft Engines ◽  
Engine Efficiency ◽  
Other Hand ◽  
Turbojet Engine ◽  
Low Emission ◽  
Civil Aircraft ◽  
The One

Restrictions of emissions for civil aircraft engines, on the one hand, and the need in increasing the engine efficiency, on the other hand, cause difficulties during development of low-emission combustors for such engines.

scholarly journals Current Status of Putative Animal Sources of SARS-CoV-2 Infection in Humans: Wildlife, Domestic Animals and Pets

2021 ◽  
Vol 9 (4) ◽  
pp. 868
Author(s):  
Max Maurin ◽  
Florence Fenollar ◽  
Oleg Mediannikov ◽  
Bernard Davoust ◽  
Christian Devaux ◽  
...  
Keyword(s):  
Animal Species ◽  
Biological Properties ◽  
Experimental Models ◽  
Current Data ◽  
The Body ◽  
Receptor Expression ◽  
Current Status ◽  
Susceptible Animal

SARS-CoV-2 is currently considered to have emerged from a bat coronavirus reservoir. However, the real natural cycle of this virus remains to be elucidated. Moreover, the COVID-19 pandemic has led to novel opportunities for SARS-CoV-2 transmission between humans and susceptible animal species. In silico and in vitro evaluation of the interactions between the SARS-CoV-2 spike protein and eucaryotic angiotensin-converting enzyme 2 (ACE2) receptor have tentatively predicted susceptibility to SARS-CoV-2 infection of several animal species. Although useful, these data do not always correlate with in vivo data obtained in experimental models or during natural infections. Other host biological properties may intervene such as the body temperature, level of receptor expression, co-receptor, restriction factors, and genetic background. The spread of SARS-CoV-2 also depends on the extent and duration of viral shedding in the infected host as well as population density and behaviour (group living and grooming). Overall, current data indicate that the most at-risk interactions between humans and animals for COVID-19 infection are those involving certain mustelids (such as minks and ferrets), rodents (such as hamsters), lagomorphs (especially rabbits), and felines (including cats). Therefore, special attention should be paid to the risk of SARS-CoV-2 infection associated with pets.

Crashworthiness Performance of Mass-Efficient Extruded Structures

2002 ◽  
Author(s):  
Robert R. Mayer ◽  
Weigang Chen ◽  
Anil Sachdev
Keyword(s):  
Numerical Simulations ◽  
Single Cell ◽  
Experimental Testing ◽  
Experimental Studies ◽  
Nonlinear Material ◽  
Dynamic Strain ◽  
Cell Design ◽  
Explicit Finite Element ◽  
The One ◽  
Crushing Behavior

Theoretical, numerical and experimental studies were conducted on the axial crushing behavior of traditional single-cell and innovative four-cell extrusions. Two commercial aluminum alloys, 6061 and 6063, both with two tempers (T4 and T6), were considered in the study. Testing coupons taken from the extrusions assessed the nonlinear material properties. A theoretical solution was available for the one-cell design, and was developed for the mean crushing force of the four-cell section. Numerical simulations were carried out using the explicit finite element code LS-DYNA. The aluminum alloy 6063T4 was found to absorb less energy than 6061T4, for both the one-cell and four-cell configurations. Both 6061 and 6063 in the T6 temper were found to have significant fracture in the experimental testing. Theoretical analysis and numerical simulations predicted a greater number of folds for the four-cell design, as compared to the one-cell design, and this was confirmed in the experiments. The theoretical improvement in energy absorption of 57% for the four-cell in comparison with the one-cell design was confirmed by experiment. The good agreement between the theoretical, numerical and experimental results allows confidence in the application of the theoretical and numerical tools for both single-cell and innovative four-cell extrusions. It was also demonstrated that these materials have very little dynamic strain rate effect.

scholarly journals Detection of Antibodies Against Tick-Borne Encephalitis Virus and Other Flaviviruses in a Zoological Collection in Slovenia

2021 ◽  
Vol 8 ◽  
Author(s):  
Pavel Kvapil ◽  
Joško Račnik ◽  
Marjan Kastelic ◽  
Pavlína Pittermannová ◽  
Tatjana Avšič-Zupanc ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Animal Species ◽  
Encephalitis Virus ◽  
Wild Animals ◽  
Emerging Pathogens ◽  
Vector Borne Diseases ◽  
Tick Borne Encephalitis ◽  
Zoo Animals ◽  
Exotic Animal ◽  
Tick Borne Encephalitis Virus

Monitoring infectious diseases is one of the most important pillars of preventative veterinary medicine in zoological collections. The zoo environment offers a great variety of different animal species living in proximity and in contact with small wild animals and vectors (e.g., ticks and mosquitos). In this context, tick-borne encephalitis virus (TBEV), Usutu virus (USUV), and West Nile virus (WNV) causing vector-borne diseases are emerging pathogens that raise concern. The aim of the study was to detect antibodies to selected flaviviruses in various animal species in the Ljubljana Zoo, Slovenia. In total, 874 sera from 96 animal species were tested for antibodies to TBEV by enzyme-linked immunosorbent assays (ELISA); positive samples were confirmed by a virus neutralization test (VNT) using TBEV, WNV, and USUV antigens. Antibodies to TBEV were detected by ELISA in 3.9% (34/874) of zoo animals, with 4% (30/753) in mammals and 5% (4/86) in birds; the sera of reptiles (n = 34) and amphibians (n = 1) were negative. Antibodies to TBEV were confirmed by VNT in 11 mammals; one bird was positive for both WNV and USUV. The mixture of exotic animal species and their contact with wild animals and vectors such as ticks and mosquitos suggest that screening of infectious diseases in zoo animals might provide good insight into the epizootological situation of the area. This is the first survey of TBEV, WNV, and USUV in a zoological collection in Slovenia.

scholarly journals THE STATE IN THE SYSTEM OF PROTECTING NATIONAL INTERESTS

2021 ◽  
Author(s):  
Vladimir Shedyakov ◽  
Keyword(s):  
Transition Period ◽  
The State ◽  
Economic Life ◽  
Corporate Sector ◽  
National Interests ◽  
Private Partnership ◽  
The Social ◽  
Multilateral System ◽  
The Media ◽  
The One

Optimizing transformations during the transition period requires the use of the entire multilateral system of mechanisms to protect national interests. The state occupies an essential place, in particular, the establishment of forms of public-private partnership in coordinating diverse initiatives and creative searches. At the same time, on the one hand, the independence and security of development force them to predominantly rely on their own forces. On the other hand, the refusal to unify the social structure (in particular, statehood) makes it easier to increase efficiency, flexibility and adaptability while maintaining loyalty to national foundations and traditions. The two most noticeable trends in the transformation of the state structure are the strengthening of totalitarian-corporate characteristics or features of democracy. Accordingly, the depersonalization of responsibility – or its embodiment in specific leaders is realizing. At the same time, as you know, selection and promotion in the corporate sector has nothing to do with democracy. And the processes of pathologizing political and economic life may imply a departure from general, direct, secret and equal elections to senior government positions, and include broad manipulative capabilities of the media sphere.

scholarly journals Characteristics of the endometrium in menstruating species: lessons learned from the animal kingdom†

2020 ◽  
Vol 102 (6) ◽  
pp. 1160-1169
Author(s):  
Laura Catalini ◽  
Jens Fedder
Keyword(s):  
Menstrual Cycle ◽  
Animal Species ◽  
Lessons Learned ◽  
Primate Species ◽  
Fruit Bat ◽  
Laboratory Facilities ◽  
Elephant Shrew ◽  
The One ◽  
The Individual ◽  
Rats And Mice

Abstract Here we have summarized what is currently known about menstruating animal species with special emphasis on non-primate species: length of their menstrual cycle, ovulation, implantation, placentation, decidualization, and endometrial characteristics. Having an overview of all the possible animal models that can be used to study menstruation and the menstrual cycle could be useful to select the one that better matches the needs of the individual research projects. The most promising species to study menstruation seems to be the spiny mouse Acomys cahirinus. It is a rodent that could be easily held in the existing laboratory facilities for rats and mice but with the great advantage of having spontaneous menstruation and several human-like menstrual cycle characteristics. Among the species of menstruating bats, the black mastiff bat Molossus ater and wild fulvous fruit bat Rousettus leschenaultii are the ones presenting the most human-like characteristics. The elephant shrew seems to be the less suitable species among the ones analyzed. The induced mouse model of menstruation is also presented as an adaptable alternative to study menstruation.

scholarly journals An Overview of SARS-CoV-2 and Animal Infection

2020 ◽  
Vol 7 ◽  
Author(s):  
Mohamed A. A. Mahdy ◽  
Waleed Younis ◽  
Zamzam Ewaida
Keyword(s):  
Intermediate Host ◽  
Animal Species ◽  
Experimental Studies ◽  
Short Review ◽  
World Health ◽  
Wholesale Market ◽  
Animal Infection ◽  
Rapid Spread ◽  
Novel Coronavirus ◽  
Health Organization

A novel coronavirus has been reported as the causative pathogen of the Coronavirus disease 2019 (COVID-19) outbreak in Wuhan city, China in December 2019. Due to the rapid spread of the virus worldwide, it has been announced as a pandemic by the World Health Organization (WHO). Hospitalized patients in Wuhan were associated with the Huanan seafood wholesale market where live animals, such as poultry, bats, snakes, frogs, rabbits, marmots, and hedgehogs are sold in that market which suggests a possible zoonotic infection. It was suggested that bat is the natural host of SARS-CoV-2, but the intermediate host is still unclear. It is essential to identify the potential intermediate host to interrupt the transmission chain of the virus. Pangolin is a highly suspected candidate as an intermediate host for SARS-CoV-2. Recently, SARS-CoV-2 infection has been reported in cats, dogs, tigers, and lions. More recently SARS-CoV-2 infection affected minks severely and zoonotic transfer with a variant SARS-CoV-2 strain evidenced in Denmark, Netherlands, USA, and Spain suggesting animal-to-human and animal-to-animal transmission within mink farms. Furthermore, experimental studies documented the susceptibility of different animal species to SARS-CoV-2, such as mice, golden hamsters, cats, ferrets, non-human primates, and treeshrews. It is also essential to know the possibility of infection for other animal species. This short review aims to provide an overview on the relation between severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and animals.

Sign in / Sign up

Export Citation Format

Share Document