THE STATE OF CHILDREN MASTICATORY MUSCLES WITH DENTITION DEFECTS IN THE FRONTAL AREA AND NARROWING OF DENTAL ARCHES IN THE TRANSVERSE PLANE

Orthopedic and orthodontic treatment of 49 patients aged 6 to 17 years with dentition defects in the frontal area was examined and performed to conduct and determine the state of the masticatory muscles in children with dentition defects. Patients were divided into two groups depending on the period of formation of the dento-maxillaire system and each of the groups was divided into two subgroups depending on the method of treatment and the mechanism of fixation of the orthodontic appliance in the oral cavity. When comparing the indicators between groups I A and I B, we can state that there were more qualitative and dynamic changes in electromyographic indicators in children of group I B than group I A. When comparing the data received after orthopedic and orthodontic treatment of children in group II, we can state that quantitative and qualitative indicators of electromyography for group II B were better than those of children in group II A. In children who were treated with removable appliances, these indicators improved, but remained at a worse level than in those treated with non-removable appliances.

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(Preprint)

10.2196/preprints.12282 ◽

2018 ◽

Author(s):

Dr Malathi Dayalan ◽

Dr Sudeshna Sharma ◽

Dr Shweta Poovani ◽

Dr Saher Altaf

Keyword(s):

Myofascial Pain ◽

Mouth Opening ◽

Masticatory Muscles ◽

Matched Pair ◽

Masticatory Muscle ◽

Muscle Disorders ◽

Occlusal Contact ◽

Group I ◽

Group Ii

BACKGROUND Masticatory system is a complex functional unit, primarily engaged in chewing, swallowing and breathing functions, and some parts are involved in taste recognition and determination of food consistency. Sophisticated functional performances of speech and emotional expressions are specifically human qualities. Irregularities in occlusion appears to be the precipitating factor in the pathogenesis of myofascial pain dysfunction syndrome. Tek- Scan III records the bite length, number, distribution, timing, duration and the relative force of each tooth contact. It also records the sequence of occlusal contacts in terms of time and the associated force with each occlusal contact. The aim of this study was to treat masticatory muscle disorders with occlusal equilibration, and compare the efficacy of treatment outcomes between selective grinding and stabilization splints using Tek-Scan III. OBJECTIVE Objective of this study was to compare the efficacy of occlusal equilibration achieved through selective griding and stabilization splints using Tek-Scan III. METHODS In this in vivo study, 40 patients with masticatory muscle disorders were selected based on the inclusion and exclusion criteria. The occlusal discrepancies were analyzed using Tek-Scan III. The selected 40 subjects were then randomly divided into 2 groups based on the treatment they recieved; Group I – Selective grinding group (20) and Group II – Stabilization splint group (20). Comparison of pre-treatment and post treatment results were evaluated in terms of pain, mouth opening, left and right side force percentage as recorded through Tek-Scan III and reduction of disclusion time. Statistical analysis was carried out with Kolmogorov Smirnov test, Wilcoxon matched pair test and Mann-Whitney U test. RESULTS Wilcoxon matched pairs test demonstrated that there was statistically significant results ( p = 0.0007) in both the groups for reduction of disclusion time, elimination of pain and improved mouth opening. Patients in Group I showed better results as compared to Group II in terms of disclusion time, pain and mouth opening. CONCLUSIONS Occlusal equilibration brought about by reducing the disclusion time using the Tek- Scan III reduced the symptoms of pain in masticatory muscles. Patients in group I (Selective grinding) however showed better results when compared to patients in group II (Stabilization splints).

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Autoantibody as markers of the heart state in patients with vibration disease burdened diabetes mellitus

Medical Immunology (Russia) ◽

10.15789/1563-0625-aam-1739 ◽

2020 ◽

Vol 22 (2) ◽

pp. 311-318

Author(s):

L. B. Masnavieva ◽

I. V. Kudaeva ◽

Yu. A. Kuznetsova

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Thrombus Formation ◽

The State ◽

Myocardial Cells ◽

Diabetes Group ◽

Vibration Disease ◽

Group I ◽

Group Ii

Physical and chemical factors, obesity, lipid metabolism disorder, diabetes affect the state of the vascular endothelium, the processes of thrombus formation, fibrinolysis and increase the risk of developing cardiovascular diseases. It can be assumed that the development and course of pathological processes in the cardiovascular system, caused by vibration disease with the onset of diabetes, will undergo changes. The purpose of the study was to assess the state of heart condition according to the level of specific autoantibodies with the combined effect of vibration disease and type 2 diabetes mellitus. Patients with vibration disease (group I), patients with type 2 diabetes (group II) and persons with vibration disease in combination with type 2 diabetes (group III) were examined. Individuals do not have a history of coronary heart disease, stroke, and myocardial infarction have been included in obsledrovanie. Serum levels of specific autoantibodies characterizing the state of the heart have been studied. It was revealed that the content of autoantibodies to 1-adrenoreceptors in patients of group I was higher than in individuals of group II. The relative content of autoantibodies to the components of the membrane and cytoplasm of myocardial cells in patients of groups I-III did not differ. It was found that elevated levels of autoantibodies to components of the membrane and cytoplasm of myocardial cells, cardiomyosin, 1-adrenoreceptors were observed more often in patients with vibration disease combined with diabetes and in persons with vibration disease than in people with diabetes. Persons with a reduced content of autoantibodies to 1-adrenergic receptors were not detected among patients of groups I and III. Changes in the levels of specific autoantibodies in persons with vibration disease may indicate the development of functional metabolic and structural changes in the heart, disorders of its electrical activity that have not yet been manifested in the form of a pathological process. Lower levels of 1-adrenoceptor autoantibodies in patients with type 2 diabetes without vibration disease can be caused by increased levels of catecholamines, which is characteristic of diabetics. Further research, including clinical data and indicators of functional diagnostics is necessary to confirm our assumptions.

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Clinic Results of Intraductal Meibomian Gland Probing Combined Intense Pulsed Light in Treating Patients With Refractory Obstructive Meibomian Gland Dysfunction: A Randomized Controlled Trial

10.21203/rs.2.4294/v1 ◽

2019 ◽

Author(s):

Xiaodan Huang ◽

Qiyu Qin ◽

Linping Wang ◽

Jiao Zheng ◽

Lin Lin ◽

...

Keyword(s):

Controlled Trial ◽

Symptom Relief ◽

Meibomian Gland ◽

Intense Pulsed Light ◽

Meibomian Gland Dysfunction ◽

Pulsed Light ◽

Group I ◽

Final Treatment ◽

Group Ii ◽

Better Than

Abstract Background: To optimize therapeutic regimen for refractory obstructive meibomian gland dysfunction (o-MGD) patients by combining intraductal meibomian gland probing (MGP) and intense pulsed light (IPL) to enhance their effect and reduce their limitations. Methods: This randomized, assessor blind study include 45 patients (90 eyes) with refractory o-MGD. They were divided into 3 groups by allocation concealment: IPL (group I, received an IPL treatment course: 3 times at 3-week intervals), MGP (group II, received MGP one time) and MGP combined IPL (group III, MGP at first then an IPL treatment course). Standard Patient Evaluation of Eye Dryness score (SPEED), tear break-up time (TBUT), corneal fluorescein staining (CFS), meibum grade and lid margin finding results were assessed at baseline, 3 weeks after final treatment in group I and III, 3 and 12 weeks after MGP in group II. Six months after final treatment, the SPEED and willingness to receive any treatment again were also collected in all groups. Paired Wilcoxon, Mann-Whitney U with Bonferroni correction and Kruskal-Wallis tests were used for data analysis. Results: In 3 groups, all above indexes improved significantly after treatment (all P＜0.01). MGP-IPL was better than IPL and MPG in posttreatment SPEED, TBUT, meibum grade, lid telangiectasia (all P＜0.05/3). Besides, the MGP-IPL was better than IPL in lid tenderness and better than MGP in orifices abnormality (all P＜0.05/3 ). Six months later, the SPEED in MGP-IPL was also significantly lower than other groups (all P＜0.05/3). And no patients in MGP-IPL group revealed the need to be treated again, while 35.7% or 20% of patients with IPL or MGP need retreatment. Conclusions: Compared with single IPL or MGP, the combination of MGP and IPL demonstrated the most efficient results in relieving all signs and symptoms and can help patients attain the most lasting symptom relief. Trial registration: http://clinicaltrials.gov, ChiCTR1900021273 (retrospectively registered 09 February 2019). Funding: This work was supported by the National Natural Science Foundation of China: [grant numbers: 81870624; 81700802]; Major Science and Technology Projects of Zhejiang Province [grant numbers: 2017C03046].

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Clinical results of Intraductal Meibomian gland probing combined with intense pulsed light in treating patients with refractory obstructive Meibomian gland dysfunction: a randomized controlled trial

BMC Ophthalmology ◽

10.1186/s12886-019-1219-6 ◽

2019 ◽

Vol 19 (1) ◽

Cited By ~ 3

Author(s):

Xiaodan Huang ◽

Qiyu Qin ◽

Linping Wang ◽

Jiao Zheng ◽

Lin Lin ◽

...

Keyword(s):

Meibomian Gland ◽

Intense Pulsed Light ◽

Meibomian Gland Dysfunction ◽

Pulsed Light ◽

Positive Effects ◽

Link Type ◽

Group I ◽

Final Treatment ◽

Group Ii ◽

Better Than

Abstract Background This study aims to optimize the therapeutic regimen for refractory obstructive meibomian gland dysfunction (o-MGD) patients by combining intraductal meibomian gland probing (MGP) and intense pulsed light (IPL) to enhance their positive effects and reduce their limitations. Methods This randomized, assessor blind study includes 45 patients (90 eyes) with refractory o-MGD who were divided into 3 groups via allocation concealment: IPL (group I, received an IPL treatment course: 3 times at 3-week intervals), MGP (group II, received MGP one time), and combined MGP-IPL (group III, MGP first followed by an IPL treatment course). Standard Patient Evaluation of Eye Dryness score (SPEED), tear break-up time (TBUT), corneal fluorescein staining (CFS), meibum grade, and lid margin finding results were assessed at baseline, 3 weeks after final treatment for groups I and III, 3 and 12 weeks after MGP for group II. Six months after final treatment, the SPEED and willingness to receive any treatment again were also collected for all groups. Paired Wilcoxon, Mann-Whitney U with Bonferroni correction, and Kruskal-Wallis tests were used for data analysis. Results For all 3 groups, all previously mentioned indexes improved significantly following treatment (P<0.01). MGP-IPL was better than IPL and MGP in terms of post-treatment SPEED, TBUT, meibum grade, and lid telangiectasia (P<0.05/3). Furthermore, the MGP-IPL was better than IPL in terms of lid tenderness and better than MGP in terms of orifice abnormality (P< 0.05/3). Six months later, the SPEED for the MGP-IPL was also significantly lower than other groups (P<0.05/3). Moreover, no patients in the MGP-IPL group expressed the need to be treated again compared to 35.7% or 20% of patients in the IPL or MGP groups, respectively. Conclusions Compared with IPL or MGP alone, the combination MGP-IPL produced best results in relieving all signs and symptoms and helping patients attain long-lasting symptom relief. Trial registration http://clinicaltrials.gov, ChiCTR1900021273 (retrospectively registered February 9, 2019).

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KOMBINASI PERCEPTUAL MOTOR PROGRAM DAN NEURODEVELOPMENTAL TREATMENT LEBIH BAIK DARIPADA KOMBINASI KINESIOTAPING DAN NEURODEVELOPMENTAL TREATMENT DALAM MENINGKATKAN KEMAMPUAN DUDUK PENDERITA CEREBRAL PALSY

Sport and Fitness Journal ◽

10.24843/spj.2018.v06.i02.p04 ◽

2018 ◽

Author(s):

Listya Triandari ◽

Ketut Tirtayasa ◽

Muhammad Irfan ◽

Desak Made Wihandani ◽

Bagus Komang Satriyasa ◽

...

Keyword(s):

Cerebral Palsy ◽

Motor Program ◽

Test Design ◽

Brain Growth ◽

Group I ◽

Post Test ◽

Group Ii ◽

Cerebral Palsy Patient ◽

Better Than

One of the deviation on brain growth was cerebral palsy (CP). The problem in cerebral palsy patient was inability to sitting. The aim of this study is to prove that additional of perceptual motor program is better than kinesiotaping in neurodevelopmental treatment in improving ability sitting in cerebral palsy patients. The method of study was pre and post test design. Fourteen cerebral palsy children with quadriplegi type that unable to sit as the sample in this study. The samples divided into two group that was group I (perceptual motor program and neurodevelopmental treatment) and group II (kinesiotaping and neurodevelopmental treatment). The intervention was applied in 60’ per session, twice session per week for 12 weeks. The score of measurement was measured by Level of Sitting Scale (LSS). The result of research showed (1) improvement of the LSS score in the group I as pre test 1.86 ± 0.69 and post test 4.00 ± 0.82, (2) improvement of the LSS score in the group II as pre test 2.00 ± 0.82 and post test 2.86 ± 1.07, (3) there was significance difference of the LSS score between group I and II with p = 0.029 (p < 0,05). It was concluded that the combination of perceptual motor program and neurodevelopmental treatment was better than the combination of kinesiotaping and neurodevelopmental treatment in increase sitting ability in cerebral palsy patients.

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A note on the effect of weaning age on lamb production

Animal Science ◽

10.1017/s0003356100028610 ◽

1969 ◽

Vol 11 (4) ◽

pp. 569-572

Author(s):

M. A. Sharafeldin ◽

I. A. Ramadan

Keyword(s):

Mortality Rates ◽

The Body ◽

The Other ◽

Suckling Period ◽

Group Iii ◽

Group I ◽

Body Weights ◽

Weaning Age ◽

Group Ii ◽

Better Than

SUMMARYAt birth, the Barki lambs used in this experiment were randomly allocated to three groups which numbered 133, 126 and 154 lambs of both sexes weaned at the ages of 10 weeks (Group I), 12 weeks (Group II) and 16 weeks (Group III) respectively.The most pronounced differences between the three groups of lambs in their body weights took place at the age from 4 to 6 months. Group II lambs performed as well as or even slightly better than the other two groups, which leads to the conclusion that as far as the body weight of lambs is concerned there is no need to extend their suckling period more than 12 weeks.The three groups of lambs varied little in their mortality rates from 2·5 to 12 months of age.

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Evaluation and Comparison of Quantity and Pattern of Fluoride release from Orthodontic Adhesives: An in vitro Study

The Journal of Contemporary Dental Practice ◽

10.5005/jp-journals-10024-1495 ◽

2014 ◽

Vol 15 (1) ◽

pp. 99-102 ◽

Cited By ~ 1

Author(s):

Devatha Ashok Babu ◽

Sanjay Krishna Sriram ◽

Ravindra Reddy Regalla ◽

Chandulal Jadav ◽

Roopa Rani S Sriram

Keyword(s):

Orthodontic Treatment ◽

Control Group ◽

Base Line ◽

Fluoride Release ◽

Group Iii ◽

Orthodontic Adhesives ◽

Group I ◽

Group Ii ◽

Topical Fluoride

ABSTRACT Background Orthodontic treatment has gained popularity since beginning of era of dentistry. Now a day, everyone is conscious about their appearance, smile and function. During orthodontic treatment use of brackets and adhesives are common. The bonding of brackets will cause demineralization which requires the fluoridation. So the study has been undertaken to analyze the pattern of fluoride release by commercially available adhesive bonding material for the prevention of demineralization. Aim To evaluate and compare the clinical significance of quantity and pattern of fluoride release from three commercially available adhesives. Objectives To assess the pattern of fluoride release and quantity, to reduce the decalcification of enamel around orthodontic brackets and bands during treatment and to prevent further use of topical fluoride both office and self-use agents for prevention of demineralization/for remineralization. Materials and methods The comparison of quantity and pattern of fluoride release study involved commercially available bonding adhesives. They are: Group I—resin reinforced glass Ionomer light cure material (OrthoLC), Group II—fluoride releasing composite resin material (Excel) and Group III— conventional composite (Relay-a-bond) evaluated on 78 freshly extracted premolar teeth divided into three groups consisting 26 specimens in each group. The prepared specimens were stored in artificial saliva at 37°C in an incubator for subsequent fluoride analysis using ORION ion selective electrode coupled with ionalyzer 901. Fluoride analysis made at 24 hours intervals for first 3 consecutive days and thereafter at the end of 10th, 17th, 24th and 31st day of bonding. The data obtained were tabulated and interpreted by statistical analysis using ‘t’ test and one-way analysis of variance (ANOVA). Observations and Results The quantity of fluoride release in groups I and II was significant even at the end of 31st day. The one-way AVOVA showed intra and inter group significance in the quantity of fluoride release. But group III with zero fluoride release with significant decalcification on enamel which requires external use of topical fluorides. The pattern of fluoride released was 3.06 ppm for group I and 2.01 ppm for group II and was declined sharply after 24 hours; and continued to decline in subsequent weeks. Mean quantity of fluoride release by group I was 15.08 ppm were as group II was 9.02 ppm over the test period of 31 days. At the end of 31st day the group I bonding adhesive was releasing considerable amount of fluoride compared to group II whereas group III was nil. At all the periods inter and intra group mean values were highly significant. And group III acted as base line or control group as it was non fluoride releasing material. Conclusion Both the fluoride releasing adhesive bond material are useful to reduce the risk of demineralization and further prevent the usage of topical fluoride application and reduce cost and clinical visiting time for both patient and clinician. How to cite this article Regalla RR, Jadav C, Babu DA, Sriram RRS, Sriram SK, Kattimani VS. Evaluation and Comparison of Quantity and Pattern of Fluoride release from Orthodontic Adhesives: An in vitro Study. J Contemp Dent Pract 2014;15(1):99-102.

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Use of Noninvasive Cerclage in Combination of Micronized Progesterone in Miscarriage Of Multifetal Pregnancy

Galician Medical Journal ◽

10.21802/gmj.2017.4.10 ◽

2017 ◽

Vol 24 (4) ◽

Author(s):

Iryna Nikitina ◽

Alla Boychuk ◽

Valentina Kondratiuk ◽

Tatyana Babar

Keyword(s):

High Risk ◽

Pregnant Women ◽

The State ◽

Control Group ◽

Group I ◽

Prophylactic Measures ◽

Neonatal Adaptation ◽

Group Ii ◽

Multifetal Pregnancy ◽

Micronized Progesterone

We represent the results of the combined method of treatment and prevention of miscarriage in women with a multiple pregnancy and a high risk of the threat of termination the pregnancy because of using the obstetric unloading pessaries, combined with micronized progesterone. The efficiency of this method of treatment is evidenced by the rapid elimination of clinical symptoms of threatened abortion, accelerating the regression of ultrasound markers, reducing the number of complications in of pregnant women and reducing the time of their stay in hospital.Goal: To evaluate the effectiveness of the handling the obstetric pessary in combination with micronized progesterone at women with multifetal pregnancy and a high risk of miscarriage.Materials and methods. We analyzed 120 cases of multifetal pregnancies with signs of miscarriage within the terms from 16 to 28 weeks. The first group of the examined women was: 40 pregnant women with twins and signs of miscarriage, who in the scheme of treatment and prophylactic measures were offered to use the unloading obstetric pessaries in combination with continuous therapy by natural micronized progesterone until 36 weeks of pregnancy. The second group included 40 pregnant women with twins, who were laid seam on the cervix because of istmicocervical insufficiency and were applied short-term courses of therapy by gestagens. The control group comprised 40 pregnant women with twins at the age of 16-28 weeks of pregnancy who were conducted the therapy about the threat of miscarriage according to the current clinical protocols (Order of the Ministry of Health of Ukraine No. 624). It was carried out the analysis of the course of pregnancy, childbirth, the postpartum period and the state of neonatal adaptation in the surveyed groups.Results of the research and their discussion. In the first group, urgent childbirth occurred in 34 (85%) cases, in group II in 29 (72.5%) cases, in control group – in 25 (62.5%) cases. Cesarean delivery was performed in 7 (17.5%) patients of group I pregnant women, in 9 (22.5%) of group II patients and in 11 (27.5%) in the pregnant group. When studying the state of neonatal adaptation of newborns in the examined groups, the following results were obtained. The average weight of the newborns in group I was 3245 ±280 g, in group II 2865 ±365 g, in the control group - 2975 ±325 g (p>0.05). The evaluation of the state of newborns on the Apgar scale, respectively at the 1st and 5th minutes, was respectively: in newborns of the I group, 7.5 ± 1.4 and 8.4 ± 1.3 points, in group II - 7.3 ± 1.6 and 8.2 ± 1.1 points, in the control group – 7.2 ± 1.6 and 8.6 ± 1.2 (р 1-р 2> 0.05).Conclusions. Comprehensive prophylaxis of non-pregnancy in multiple pregnancies, combining the use of a traumatic cardiac cervix with the help of unloading obstetric pussies with progesterone preparations, allows prolonging pregnancy, preventing the development of prematurity, contributes to the improvement of perinatal indicators.

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The Use of the Test for Oral Muscular Coordination Ability to Increase the Level of Adaptive Capacity of Oral Cavity Organs to Prosthodontic Treatment of Patients with Completely Absent Dentition

Galician Medical Journal ◽

10.21802/gmj.2019.4.2 ◽

2019 ◽

Vol 26 (4) ◽

Author(s):

Volodymyr Sarapuk

Keyword(s):

Oral Cavity ◽

Adaptive Capacity ◽

Masticatory Muscles ◽

Tactile Sensitivity ◽

Standard Samples ◽

Group I ◽

Coordination Ability ◽

Group Ii ◽

Muscular Coordination ◽

Stimulation Group

Increase in the level of adaptive capacity of oral cavity organs to the prosthodontic treatment of patients with completely absent dentition is one of the urgent problems of modern dentistry. In order to increase the level of adaptability to complete removable laminar dentures, a set of standard samples according to H. Landt was used to test the ability for precise coordination of masticatory muscles – the MA-test (Muscular-Ability) as a means of a group of muscles stimulation providing precise coordination of masticatory muscles. This adaptation process was called MA-stimulation. The level of adaptive capacity of the oral cavity organs was studied using oral stereognosis. The criteria for oral stereognosis assessment included the average time of one sample determination (sec) and the correctness of the samples determination (%). In order to achieve the objective, we conducted a study of tactile sensitivity in the oral cavity using oral stereognosis in 90 patients with completely absent dentition who applied for the prosthodontic retreatment. The patients’ age ranged from 45 to 89 years. The patients were divided into two groups. Group I included 30 patients who underwent the prosthodontic treatment without preliminary MA-stimulation. Group II included 60 patients who underwent MA-stimulation for 14 days before the prosthodontic treatment. According to the results of oral stereognosis in Group II of patients, the average time of one sample determination after fourteen days of MA-stimulation decreased by 24.5% (p˂0.05) and the index of correctness of the samples determination increased by 32.0% (р˂0.001); the average time of one sample determination decreased by another 19.3% in 1 month after the prosthodontic treatment, and it decreased by 17.4% (р˂0.05) in 3 months after the prosthodontic treatment; the index of the correctness of the samples determination increased by 17.5% (p˂0.001) and 10.5% (p˂0.01) respectively in 1 and 3 months after the prosthodontic treatment. Oral stereognosis indices changed significantly only in 1 month after the prosthodontic treatment in Group I of patients who did not undergo MA-stimulation: the average time of one sample determination decreased only by 14.7% (p˂0.05), and the index of correctness of the samples determination increased only by 24.5 (p˂0.05). According to the results of the research, MA-stimulation is advisable to be included into the prosthodontic treatment of the patients with completely absent dentition as a means of increasing the adaptive capacity of the oral organs.

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Use of bacterial cellulose in closure of nasal septal perforation

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20192701 ◽

2019 ◽

Vol 5 (4) ◽

pp. 830

Author(s):

Yasser Mohammad Hassan Mandour ◽

Mohammed Fahmy Shendy ◽

Samer Badie ◽

Ahmed Elrefai ◽

Samira Mohammed ◽

...

Keyword(s):

Bacterial Cellulose ◽

Randomized Study ◽

Inferior Turbinate ◽

Septal Deviation ◽

Surgical Correction ◽

Septal Perforation ◽

Nasal Septal Perforation ◽

Group I ◽

Group Ii ◽

Better Than

Background: 30 patients with nasal septal perforation after surgical correction of septal deviation undergoing trials of septal closure were divided into 2 groups to compare between results of free inferior turbinate graft with bacterial cellulose and results of free inferior turbinate graft only in closure of nasal septal perforation. To compare between results of free inferior turbinate graft with bacterial cellulose and results of free inferior turbinate graft only in closure of nasal septal perforation.Methods: Prospective randomized study in which 30 patients with nasal septal perforation after surgical correction of septal deviation undergoing trials of septal closure were divided into 2 groups; group I (15 patients) in which free inferior turbinate graft with bacterial cellulose would be used in closure of nasal septal perforation; group II (15 patients) in which free inferior turbinate graft only would be used in closure of nasal septal perforation. Results: Septal perforation healing (closure) would be in 10 patients in group I while in 6 patients in group II. Improvement in nasal obstruction, crustion, epistaxis and breathing sound in group I would be better than in group II.Conclusions: Use of free inferior turbinate graft with bacterial cellulose would be an effective method than use of free inferior turbinate graft only in closure of nasal septal perforation.

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