Between Hammer and Anvil

Author(s):  
A. Wess Mitchell

This chapter traces the breakdown of the Metternichian system, from the time of the revolution of 1848 and Crimean War to the debilitating defeats by Italy in 1859 and Prussia in 1866. In the middle decades of the nineteenth century, the Habsburg Monarchy suffered defeats in a series of short, sharp wars that would bring an end to the Metternich system and pave the way for Austria’s demise as a Great Power. These changes occurred not primarily because of economic decay or the empire’s internal complexity but instead because Austria lost the tools that it had used in the past to manage the sequencing and duration of its wars. This was the result of both structural changes beyond its leaders’ control and avoidable errors and a deviation from the principles that had formerly shaped its past statecraft. Specifically, Austria’s leaders abandoned the flexible statecraft that had allowed them to control conflict sequencing and avoid isolation; rivals adopted new technologies that denied the monarchy’s armies the ability to use attrition and terrain to prolong conflict and outlast stronger militaries; and nationalism trumped treaty rights as a source of territorial legitimacy, allowing hostile polities to form in the areas that had previously served as the monarchy’s buffer zones. Deprived of its traditional strategic toolbox, Austria was forced by its strongest rival to accept cohabitation with its strongest ethnic minority and for the first time had to absorb the full costs of managing a 360-degree defensive position.

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Vihang S. Thite ◽  
Anuradha S. Nerurkar

Abstract After chemical pretreatment, improved amenability of agrowaste biomass for enzymatic saccharification needs an understanding of the effect exerted by pretreatments on biomass for enzymatic deconstruction. In present studies, NaOH, NH4OH and H2SO4 pretreatments effectively changed visible morphology imparting distinct fibrous appearance to sugarcane bagasse (SCB). Filtrate analysis after NaOH, NH4OH and H2SO4 pretreatments yielded release of soluble reducing sugars (SRS) in range of ~0.17–0.44%, ~0.38–0.75% and ~2.9–8.4% respectively. Gravimetric analysis of pretreated SCB (PSCB) biomass also revealed dry weight loss in range of ~25.8–44.8%, ~11.1–16.0% and ~28.3–38.0% by the three pretreatments in the same order. Release of soluble components other than SRS, majorly reported to be soluble lignins, were observed highest for NaOH followed by H2SO4 and NH4OH pretreatments. Decrease or absence of peaks attributed to lignin and loosened fibrous appearance of biomass during FTIR and SEM studies respectively further corroborated with our observations of lignin removal. Application of commercial cellulase increased raw SCB saccharification from 1.93% to 38.84%, 25.56% and 9.61% after NaOH, H2SO4 and NH4OH pretreatments. Structural changes brought by cell wall degrading enzymes were first time shown visually confirming the cell wall disintegration under brightfield, darkfield and fluorescence microscopy. The microscopic evidence and saccharification results proved that the chemical treatment valorized the SCB by making it amenable for enzymatic saccharification.


2019 ◽  
Vol 36 (2) ◽  
pp. 21-22
Author(s):  
Ray Harper

Purpose The purpose of this paper is to summarise a number of presentations at Day 1 of the Internet Librarian International conference, London, UK (16 October 2018). This was the 20th conference in the series, and the three key themes included were the next-gen library and librarian; understanding users, usage and user experience; and inclusion and inspiration: libraries making a difference. Design/methodology/approach This paper reports from the viewpoint of a first-time attendee of the conference. This summarises the main issues raised by each presentation and draws out the key learning points for practical situations. Findings The conference covered a variety of practical ways in which libraries can use technology to support users and make decisions about services. These include developing interactive physical spaces which include augmented reality; introducing “chat-bots” to support users; using new techniques to analyse data; and piloting new ways to engage users (such as coding clubs). A key theme was how we use and harness data in a way that is ethical, effective and relevant to library services. Originality/value This conference focussed on practical examples of how library and information services across sectors and countries are innovating in a period of huge change. The conference gave delegates numerous useful ideas and examples of best practice and demonstrated the strength of the profession in adapting to new technologies and developments.


Pharmaceutics ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1051
Author(s):  
Jonattan Gallegos-Catalán ◽  
Zachary Warnken ◽  
Tania F. Bahamondez-Canas ◽  
Daniel Moraga-Espinoza

Orally inhaled drug products (OIDPs) are an important group of medicines traditionally used to treat pulmonary diseases. Over the past decade, this trend has broadened, increasing their use in other conditions such as diabetes, expanding the interest in this administration route. Thus, the bioequivalence of OIDPs is more important than ever, aiming to increase access to affordable, safe and effective medicines, which translates into better public health policies. However, regulatory agencies leading the bioequivalence process are still deciding the best approach for ensuring a proposed inhalable product is bioequivalent. This lack of agreement translates into less cost-effective strategies to determine bioequivalence, discouraging innovation in this field. The Next-Generation Impactor (NGI) is an example of the slow pace at which the inhalation field evolves. The NGI was officially implemented in 2003, being the last equipment innovation for OIDP characterization. Even though it was a breakthrough in the field, it did not solve other deficiencies of the BE process such as dissolution rate analysis on physiologically relevant conditions, being the last attempt of transferring technology into the field. This review aims to reveal the steps required for innovation in the regulations defining the bioequivalence of OIDPs, elucidating the pitfalls of implementing new technologies in the current standards. To do so, we collected the opinion of experts from the literature to explain these trends, showing, for the first time, the stakeholders of the OIDP market. This review analyzes the stakeholders involved in the development, improvement and implementation of methodologies that can help assess bioequivalence between OIDPs. Additionally, it presents a list of methods potentially useful to overcome some of the current limitations of the bioequivalence standard methodologies. Finally, we review one of the most revolutionary approaches, the inhaled Biopharmaceutical Classification System (IBCs), which can help establish priorities and order in both the innovation process and in regulations for OIDPs.


2021 ◽  
Vol 91 (13-14) ◽  
pp. 1609-1626
Author(s):  
Yuran Jin ◽  
Xiangye Song ◽  
Jinhuan Tang ◽  
Xiaodong Dong ◽  
Huisheng Ji

The research on the business model of garment enterprises (BMGE) has expanded rapidly in the last decade. However, there is still a lack of comprehensive reviews of it, let alone visual research. Based on scientometrics, in this paper 118 papers and their 4803 references from Science Citation Index Expanded, Social Sciences Citation Index, Conference Proceedings Citation Index—Science, and Conference Proceedings Citation Index—Social Science & Humanities for the period 2010–2020 about the BMGE were analyzed by visualizing the co-cited references, co-occurrence keywords, burst references, dual-map overlays, and more with CiteSpace, Google Maps, and VOSviewer. The research revealed the intellectual landscapes of the BMGE for the first time and mapped the landmark papers, hotspots and trends, national or regional distributions and their cooperation networks, highly cited authors, and prestigious journals and disciplines related to the BMGE. The results show that the biggest hotspot is the fast fashion business model; social responsibility, smart fashion, Internet of Things, and sharing fashion are the main emerging hotspots; and the research focuses has evolved from traditional business models to business models driven by new technologies, then to new issues such as circular economy models. The institutions are mainly distributed in China, the United States, and Western Europe, and there is cooperation between more than 11 countries. The most popular disciplines are economics and politics, while psychology, education, and social science are the essential basic disciplines. The Journal of Cleaner Production and Journal of Fashion Marketing and Management, among others, actively promoted the research.


1975 ◽  
Vol 11 ◽  
pp. 113-135 ◽  
Author(s):  
Péter Hanák

By abolishing feudalism, the Hungarian Revolution of 1848 helped to create the economic preconditions and the legal-political framework necessary for capitalistic development. This made it possible for Hungary to adapt her economy to the market possibilities offered by the Industrial Revolution in western and central Europe and to share in the agrarian boom of the period between 1850 and 1873. The previously existing division of labor between western and eastern Europe and between the western and eastern parts of the Habsburg monarchy continued on a scale larger than before, with the significant difference, however, that this practice now speeded up rather than retarded the development of preconditions for capitalism. During the first half of the nineteenth century the preconditions for capitalism had come into existence in the Cisleithanian provinces at considerable expense to the Hungarian economy.


2010 ◽  
Vol 97-101 ◽  
pp. 64-68
Author(s):  
Jian Chen ◽  
Jin Wang ◽  
Guo Dong Lu ◽  
Zheng Qi Ling

High- precision and large scale are the developing trend for injection molding machine clamping system .This paper compared the characteristics of three-platen toggle and dual-platen hydraulic clamping system. The key impact factors that effecting plastic parts` precision from clamping system were discussed systematically first time. Based on these analyses, a new clamping system has been proposed and manufactured to improve the plastics parts` precision, including three new technologies: new type dual-platen structure, parallelism adaptive correction technology and numerical controlled hydraulic servo system technology. It has been applied in practical machine successfully, and experiment result proves that it is effective enough to satisfying the high-precision molding of large plastics parts.


2021 ◽  
pp. 213-222
Author(s):  
Dandan Wu ◽  
Xiaoxia Zhu ◽  
Lu Tan ◽  
Haiqin Zhang ◽  
Lina Sha ◽  
...  

The genera of the tribe Triticeae (family Poaceae), constituting many economically important plants with abundant genetic resources, carry genomes such as St, H, P, and Y. The genome symbol of <i>Roegneria</i> C. Koch (Triticeae) is StY. The St and Y genomes are crucial in Triticeae, and tetraploid StY species participate extensively in polyploid speciation. Characterization of St and Y nonhomologous chromosomes in StY-genome species could help understand variation in the chromosome structure and differentiation of StY-containing species. However, the high genetic affinity between St and Y genome and the deficiency of a complete set of StY nonhomologous probes limit the identification of St and Y genomes and variation of chromosome structures among <i>Roegneria</i> species. We aimed to identify St- and Y-enhanced repeat clusters and to study whether homoeologous chromosomes between St and Y genomes could be accurately identified due to high affinity. We employed comparative genome analyses to identify St- and Y-enhanced repeat clusters and generated a FISH-based karyotype of <i>R. grandis</i> (Keng), one of the taxonomically controversial StY species, for the first time. We explored 4 novel repeat clusters (StY_34, StY_107, StY_90, and StY_93), which could specifically identify individual St and Y nonhomologous chromosomes. The clusters StY_107 and StY_90 could identify St and Y addition/substitution chromosomes against common wheat genetic backgrounds. The chromosomes V_St, VII_St, I_Y, V_Y, and VII_Y displayed similar probe distribution patterns in the proximal region, indicating that the high affinity between St and Y genome might result from chromosome rearrangements or transposable element insertion among V_St/Y, VII_St/Y, and I_Y chromosomes during allopolyploidization. Our results can be used to employ FISH further to uncover the precise karyotype based on colinearity of Triticeae species by using the wheat karyotype as reference, to analyze diverse populations of the same species to understand the intraspecific structural changes, and to generate the karyotype of different StY-containing species to understand the interspecific chromosome variation.


2021 ◽  
Author(s):  
Lidia Pakhomova ◽  

This monograph focuses on the activities of Russian consuls in Sarajevo, as well as the work of diplomats on the Bosnian-Herzegovinian issue both during the Great Eastern Crisis and before the Annexation Crisis. The Congress of Berlin, held after the Russian-Turkish War of 1877–78, placed the region under the control of the Habsburg Monarchy, but under the sovereignty of the Ottoman Sultan. The book shows that the Russian Military Ministry had a plan to prevent the occupation. One of the research subjects is the Russian-Austrian negotiation on the status of the provinces. The decisions made by the St Petersburg were based on an analysis of the situation in the province — the center for collecting information was the Consulate in Sarajevo, hence the author’s attention to its functioning. The assessment of the Austro-Hungarian modernisation policy in the occupied territory by the Russian Ministry of Foreign Affairs is analysed historiographically for the first time. The study of the ethnographic works by Pavel A. Rovinsky and Aleksei N. Kharuzin made it possible to trace the changes in the life of Bosnian and Herzegovinian inhabitants during the Austro-Hungarian occupation. Thus, the author attempts to demonstrate the connection between the internal development of the region and the decisions about its fate at the international level.


2021 ◽  
Author(s):  
Khaled M. Mazen Al Khoujah ◽  
Antonio - Medina ◽  
Juma Rashid Al Qaydi ◽  
Jawwad Kaleem ◽  
Fatima Hassan Al Mansoori ◽  
...  

Abstract An innovative design was implemented as a solution for the repetitive failure of a plate heat exchanger installed at Gas Processing Facilitates due to weld cracking, the new design was introduced for the first time in the facility, demonstrating the novelty of utilizing new technologies and enhanced designs in Heat Exchangers used for gas processing. The main challenges were in accommodating various operating modes and ensure the prevention of reoccurrence of the failures. The success was achieved through the collaboration between the operating company and Industry experts in heat transfer equipment to replace the existing design at the gas processing Facilitates with no change in piping layouts, hence, performing the replacement at optimal cost and maximum benefit.


Nanoscale ◽  
2019 ◽  
Vol 11 (42) ◽  
pp. 20284-20294 ◽  
Author(s):  
Yu Cheng ◽  
Pengfei Yuan ◽  
Xiaohui Xu ◽  
Sijie Guo ◽  
Kanglei Pang ◽  
...  

Operando Raman spectroscopy is used for the first time for clear identification of the intrinsic active sites, intermediates and structural changes in Mo4S16@GCA.


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