scholarly journals ROLE OF IMMATURE/TOTAL NEUTROPHIL RATIO, LEUKOCYTE COUNT AND PROCALCITONIN IN DIAGNOSING NEONATAL SEPSIS

Author(s):  
I A Putri Wirawati1 ◽  
Aryati Aryati ◽  
A A Wiradewi Lestari

Neonatal sepsis is a clinical syndrome of systemic disease, accompanied by bacteremia that occurs during infants in the first month of life. A late diagnosis might increase mortality. The presence of bacteria growth in blood cultures is a definitive diagnosis. Unfortunately, culture results are usually obtained of a long time. The study aimed to analyze sensitivity and specificity of the manual I/T ratio, automatic I/T ratio, leukocyte count and procalcitonin (PCT) to diagnose neonatal sepsis. This study used a cross-sectional design, from the NICU room in Sanglah General Hospital, Denpasar. There were 59 patients who met the study criteria. Along with blood culture as the gold standard in determining diagnosis of sepsis and with I/T ratio cut-off of 0.2, the sensitivity of manual I/T ratio was 69.2%, specificity 83.9%, PPV 63.9%, NPV 87% and likelihood ratio was 3.06. While the sensitivity of automatic I/T ratio was 47.6%, specificity 85.8%, PPV 55.1%, NPV 81.4% and likelihood ratio was 2.25. Based on the normal range of leukocyte count (9.1 - 34 x 103/μl), sensitivity of leukocyte count was 59%, specificity 71.5%, PPV 46.7%, NPV 80.9% and likelihood ratio was 1.59. With PCT cut-off 0.5 ng/mL, the obtained sensitivity of PCT was 64.3%, specificity 85.8%, PPV 64.3%, NPV 85.8% and likelihood ratio was 3.13. 

2021 ◽  
Vol 6 (2) ◽  
pp. 44-48
Author(s):  
Alpa Exaudi Siahaan ◽  
Johan Christian Silaen ◽  
Leo Simanjuntak

Background: Neonatal sepsis is a clinical syndrome on infants aged 28 days or more. According to WHO data on 19th April 2018, estimated 3 million newborns and 1.2 million children suffer from sepsis globally every year. Hematological profile assessment can be used as a clinical guide to diagnose sepsis and early management of patients with early onset, especially in hospitals with limited facilities and the examination data can be obtained faster. Objective: This study was aimed to determine the hematological profile in sepsis patients in neonatal unit at RSUD Dr. Pirngadi Medan. Method: This research was a descriptive cross-sectional design. The research sample was selected by total sampling. Results: The results of the study were found from 74 neonates, 44 (59.5%) were male. Neonates with normal labor were 57 (78.1%) and survived 45 (60.8%). It was found that leukocytes (76.4%), neutrophils (60%), monocytes (87.9%), and hemoglobin (40.3%) were increased. Conclusion: The hematological profile can be used as a clinical assessment of sepsis at the first 24 hours on neonates. Hematological examination found an increased leukocytes, neutrophils, monocytes, and hemoglobin in neonatal sepsis patients at the first 24 hours.


2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Marselli Widya Lestari ◽  
Tri Wahyuni Bintarti

Gout or Gouty Arthritis is a degenerative disease. Gouty arthritis is a clinical syndrome that is caused by deposition of purine crystals in the tissues, due to levels of uric acid (hyperuricemia) in the extracellular fluid that passes through saturation. The etiology of gout arthritis included age, sex, history of medication, obesity, consumption of purine and alcohol. Aging is an important risk factor for men and women. This study uses an analytical-descriptive approach with cross-sectional design. This study was conducted to obtain a relationship between nutritional status and uric acid levels in the community in the area of ​​Al-Hidayah Islamic Boarding School, Ngawi. This research was conducted in Majasem Village, Kendal District, Ngawi Regency, starting from 7 June - 31 August 2018. The results showed that there was a relationship between nutritional status and uric acid levels in the community in the area of ​​Al-Hidayah Islamic Boarding School, Ngawi (p=0,008). Suggestions for further research are bivariate analysis based on gender, knowledge and attitude to response to diet so that other factors that influence can be seen clearly


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Dong Ju ◽  
Jingjing Yao ◽  
Li Ma

PurposeJob involvement is an important predictor of how well employees perform and feel at work. However, despite fruitful findings, little is known about how person–job (P–J) fit affects job involvement.Design/methodology/approachThis study used a cross-sectional design and collected data from 375 employees and 50 managers. Multivariate regression was applied to test the moderated curvilinear model.FindingsThis study found an inverted U-shaped relationship between P–J fit and job involvement. For employees with a strong performance goal orientation, maximum job involvement occurred at a higher level of P–J fit, whereas for employees with a strong learning goal orientation, maximum job involvement occurred at a moderate level of P–J fit.Practical implicationsManagers should be aware that solely maximizing fit may not constantly yield positive outcomes, and that ignoring differences in employee needs and goals may be counterproductive.Originality/valueThe study challenges the conventional wisdom that a high P–J fit is always productive by showing that a high fit may sometimes jeopardize job involvement, particularly for certain employees.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Temitope Owolabi ◽  
Tunde A. Alabi ◽  
Sofiat A. Busari-Akinbode

Purpose This study aims to investigate female commercial drivers in the Lagos metropolis. The study sought to know the circumstances that motivated women to venture into commercial driving; the experiences they encounter whilst engaging with other stakeholders in the public space; the dimension of the conflict between work and family, and the coping strategies used and finally, the health concerns of female commercial drivers. Design/methodology/approach The study adopted a cross-sectional design and a qualitative method of data collection. An in-depth interview guide was used to elicit information from 18 female drivers drawn from three sectors of commercial transportation in Lagos State. Findings It was found that the major motivation for engaging in commercial driving is the need for survival and family support; although participants acknowledged that they cannot be in the profession for a long time. Married women had less time to engage in commercial driving due to other family responsibilities. Women drivers have experienced mixed reactions from other road users. Commercial driving is physically demanding and poses threat to the health of female commercial drivers. Originality/value The findings highlight the circumstances behind women participating in commercial driving. Despite the challenges encountered in this course of this activity, they are still bent on continuing because of the need to take care of their children, a majority of their spouses are not fully contributing to the maintenance of the home.


2018 ◽  
Vol 1 (1) ◽  
pp. 11-18
Author(s):  
OK. Muhammad Al Hafiz ◽  
Rina Amelia ◽  
Nelva Karmila Jusuf

Intertriginous candidiasis is a type of candidiasis which the lesion lies in the folds of the armpit, groin, intergluteal, folding of the breast, between the fingers or the toes, glans penis, and the umbilicus. One of the risk factors for intertriginous candidiasis is diabetes mellitus (DM). DM is a typical clinical syndrome characterized by the presence of hyperglycemia which is caused by deficiency or the decrease of insulin effectivity. Fungal infection of the skin with Candida species becomes easier in patients with immunocompromised conditions such as DM patients. Objective: To identify the Candida species in DM patient's skin. Method: This research is an observational descriptive study with cross sectional design. This research identifies Candida species from 30 DM patients at The Public Health Center Sentosa Baru Medan who met the inclusion and exclusion criteria by skin scraping with KOH 10% and slide culture. Results: The location of the rash was found in the crotch folds 63.3% and in the intergluteal 36.7%. All samples (100%) showed positive fungus structure with KOH 10% examination. On the examination of slide culture with Saboraoud Dextrose Agar media and identification of slide colony with Corn Meal Agar medium as many as 60% Candida spesies was found with overall species are Candida albicans.


2018 ◽  
Vol 7 (1) ◽  
pp. 65-72
Author(s):  
Barr. Emmanuel Imuetinyan Obarisiagbon ◽  
Mannie Omagie

Abstract Kidnapping for ransom has been on the increase in the last ten years in Nigeria and there appears to be no end in sight despite the existence of a police force whose statutory function of crime detection and prevention has come under fire for its abysmal performance. This study therefore examined the public perception of the role of the Nigeria police force in curbing the menace of kidnapping in Benin Metropolis, Southern Nigeria. This study adopted the problem-oriented policing theory in its explanation of the topic under investigation. It also employed the survey and cross-sectional design. The quantitative technique was utilized to collect data from the respondents while a total of 960 respondents were quantitatively sampled. Both descriptive and inferential statistics were used to analyse the quantitative data collected from the field. Findings from this investigation showed that there is a very poor public perception of the police and that there are a multiplicity of obstacles hindering the efforts of the police at curbing the activities of kidnappers in Nigeria. Based on the findings of the study, it was recommended that government should improve the funding of the police to boost the morale of the rank and file while the police on its part should get rid of the bad elements within its system in order for public confidence to be restored in its ability.


2019 ◽  
Vol 3 (1) ◽  
pp. 41-46
Author(s):  
Marselli Widya Lestari ◽  
Tri Wahyuni Bintarti

Gout or Gouty Arthritis is a degenerative disease. Gouty arthritis is a clinical syndrome that is caused by deposition of purine crystals in the tissues, due to levels of uric acid (hyperuricemia) in the extracellular fluid that passes through saturation. The etiology of gout arthritis included age, sex, history of medication, obesity, consumption of purine and alcohol. Aging is an important risk factor for men and women. This study uses an analytical-descriptive approach with cross-sectional design. This study was conducted to obtain a relationship between nutritional status and uric acid levels in the community in the area of Al-Hidayah Islamic Boarding School, Ngawi. This research was conducted in Majasem Village, Kendal District, Ngawi Regency, starting from 7 June - 31 August 2018. The results showed that there was a relationship between nutritional status and uric acid levels in the community in the area of Al-Hidayah Islamic Boarding School, Ngawi (p=0,008). Suggestions for further research are bivariate analysis based on gender, knowledge and attitude to response to diet so that other factors that influence can be seen clearly.


2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Hendrika N. C. Dewi ◽  
Michaela E. Paruntu ◽  
Murniati Tiho

Abstract: Cigarette are the most cause of death around the world. Smoking cigarrete is harmful to the organs because it contains many toxic chemical that can stimulate inflammatory process. Smoking cigarrete is a risk factors for heart disease and chronic pulmonary disease (COPD). C-reactive protein (CRP) are a non spesific inflammatory marker that can elevated in both local and systemic disease. Beside biomarker, CRP also use as prognostic marker for inflammation. The purpose of this study was to identify the level of serum CRP of smokers aged >40 years old. Twenty eight smokers were eligible to this criteria and participated in this study. Cross-sectional design with a descriptive method was employed in this study. Sampels were analysed in laboratory for serum CRP levels. The results showed that 23 subjects (82%) had normal (negatif) serum CRP level and five subjects (18%) had positive serum CRP level. It can be concluded that serum CRP level of >40 years old smokers in Kolombo village, west Bitung two were mostly in normal level.Keywords: c-reactive protein (crp), active smoker, at age >40 years oldAbstrak: Rokok menjadi salah satu penyebab kematian terbesar di dunia. Merokok membahayakan hampir semua organ tubuh karena mengandung berbagai bahan kimia berbahaya yang dapat merangsang proses peradangan dan merupakan faktor utama penyakit jantung dan penyakit paru obstruktif kronik (PPOK). C-Reactive Protein (CRP) merupakan petanda inflamasi non-spesifik yang meningkat pada penyakit lokal maupun sistemik. Selain biomarker CRP juga dijadikan sebagai penanda prognostik untuk inflamasi. Tujuan dari penelitian ini untuk mengetahui kadar CRP serum pada perokok berusia >40 tahun. Dua puluh delapan perokok memenuhi syarat untuk kriteria ini dan berpartisipasi dalam penelitian ini. Penelitian ini menggunakan desain cross-sectional dengan metode deskriptif. Kadar CRP serum sampel dianalisis di laboratorium. Hasil penelitian menunjukkan bahwa 23 subyek (82%) memiliki kadar CRP serum normal (negatif) dan lima subjek (18%) memiliki kadar CRP serum positif. Dapat disimpulkan bahwa kadar CRP serum perokok berusia >40 tahun di desa Kolombo, Bitung barat dua kebanyakan dalam kadar normal.Kata kunci: c-reactive protein (crp), perokok aktif, usia >40 tahun.


2020 ◽  
Vol 2 (1) ◽  
pp. 280-285
Author(s):  
Nelly SD Situmeang ◽  
Etti Sudaryati ◽  
Jumirah

Stunting is a chronic nutritional problem due to insufficient intake for a long time, in Indonesia the prevalence is high. The World Health Organization (WHO) classifies if the length/height z score is below −2 SD. The purpose of this study was to analyze the correlation between parenting, and nutrient intake (energy and protein) with stunting in children aged 24-59 years. This study used a cross sectional design with a sample of 117 children. Data collection was carried out with questionnaire instruments for parenting, and 24-hour food recall for nutritional intake. Data stunting was performed by comparing the height of the children measured by the WHO growth standards. Correlation analysis using Pearson correlation analysis. The results showed that the prevalence of stunting for children aged 24-59 months was 50.4%. There was a significant correlation between parenting with stunting (r = 0.287 and p = 0.02), energy intake with stunting (r = 0.215 and p = 0.020) and protein intake with stunting (r = 0.354 and p = 0.0001). It is recommended that the Ministry of Health improve nutrition surveillance programs, and encourage the community to monitor the growth of children under five years every month in health services.


2022 ◽  
Vol 7 (2) ◽  
pp. 150-160
Author(s):  
Putri Rahmadani ◽  
Besral Besral ◽  
Masrizal Masrizal

Background: The measles rubella (MR) immunization coverage rate in Padang City is only 30.82%, still far below Indonesia's national target of 95%. The coverage of measles rubella immunization at the Rawang Health Center is around 62.1%. This study aims to determine the role of health workers in the success of measles rubella immunization in the Rawang Public Health Center, Padang City. Methods: This study used a cross sectional design. The study was conducted in October 2018-July 2019. The research population is mothers who have children aged 12-59 months (toddlers) as many as 1807 respondents. The sampling method is proportional random sampling with a sample of 87 respondent. Data was collected by interview using a questionnaire. Results: The results showed that 37.9% of children under five had not been immunized against measles rubella and 44.8% of health workers had an unfavorable role. The results of the chi-square test showed a significant relationship  between  the role of officers in  the success of measles rubella immunization  (p-value=0.020). Recommendation: It is hoped that health workers can increase health promotion activities regarding the risks due to children not being immunized against measles rubella and intensify door-to-door programs in the implementation of measles rubella immunization


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