Prevalence of Diabetes Mellitus and It’s Complications in Iraq

Author(s):  
Qayssar Joudah Fadheel

Diabetes mellitus is a chronic metabolic disease characterized by long term elevation of blood glucose levels. A number of reasons that increase blood glucose level include (not enough insulin or oral diabetes drugs,too much food, adverse effects from other drugs, such as steroids, or conditions such as stress ,long- or short-term pain ,menstrual periods, dehydration). Objective: To assess the prevalence of type11 diabetic mellitus and its complications and comparison between different complications among people in Iraq. Patient: This is a randomize prospected, clinical study it was carried out in Iraqi Hospitals, Department of Medicine, emergency. This study was started at December 2016, this approved medical ethical community at University of Kufa. Methods: Sample of 100 cases (50 male and 50 female) in Iraq was selected in random manner and all the patients found in the Iraqi Hospitals at the time of visiting. Where directly meet the patients and collect data from each patient according to specific questionnaires: weight, height and blood glucose level were obtained. Materials: Blood glucose level was measure by using specific device and must keep it in suitable place with maintenance of sterility and recalibration. Further advices were taken from Departments of clinical/biomedical engineering and Local medical physics. Results: The prevalence diabetes mellitus complications among the study populationwas as follow:-(Diabetic neuropathy 98%), (Diabetes retinopathy 96%), (stroke 60%), (Diabetic nephropathy 36%), (Hypertension 63%), (foot problems 60%). A significant difference was founded between some diabetic complications, these were (Neuropathy and hypertension), (Retinopathy and hypertension), (Retinopathy and stroke), (Nephropathy and hypertension), (Nephropathy and Stroke), (Hypertension and Foot problems), (Foot problem and stroke), (Neuropathy and stroke). Conclusion: The prevalence of diabetes mellitus complications was lying within that reported in Iraq. There was a significant difference recorded between some diabetic mellitus complications. Early diagnosis of diabetes mellitus and make program to the patient about lifestyle behavior were highly considered.

Author(s):  
Aishwarya Pramod Benkar ◽  
Smita Bhimrao Kanase

Objective: Diabetes mellitus is a leading cause of death and disability in the world and its prevalence is predicted to rise to 10% by 2030. Hence, this study is conducted with objectives to find out the effect of aerobic exercises and resisted exercises on blood glucose levels in type 2 diabetes mellitus (T2DM) subjects and to compare the effect of both exercises on blood glucose level.Method: The comparative study was conducted at Krishna Institute of Medical Sciences Deemed University, Physiotherapy department, Karad. 30 participants with age group between 30 and 65 years were taken. Subjects were selected as per inclusion and exclusion criteria. Group A (15) participants were given aerobic exercise on static bicycle, and Group B (15) participants were given resistance training using dumbbells and weight cuffs for 5 days/week for 4 weeks. Diet recommendations were given to every participant.Results: Statistical analysis was performed using paired and unpaired t-test. Analysis showed statistically extremely significant difference in fasting blood glucose level and postprandial blood glucose level in both the groups (p≤0.0001).Conclusion: Thus, this study concludes that both aerobic exercises and resistance training prove to be beneficial in controlling blood glucose levels in T2DM subjects.


2009 ◽  
Vol 6 (2) ◽  
pp. 64
Author(s):  
Taufan Hendra Tandri ◽  
Wiryatun Lestariana ◽  
Fatma Zuhrotun Nisa

Background: Effective control of blood glucose and activities of antioxidant are key factors that prevent diabetes mellitus (DM) and its complications. There are lots of herbal plants that have those both effects. Ceplikan leaves (Ruellia tuberosa L.) is a traditional medicine which is empirically used to lower blood glucose level. Instead of antioxidant compound, there is assumed other compound in ceplikan leaves that has side effect to pancreatic beta cells.Objective: To identify the effect of ceplikan leaves extract to blood glucose level and pancreas histology description in white diabetic rats (Rattus norvegicus).Method: Thirty subjects of Wistar strain male white rats of 2-3 months old and of 150-200 grams weight were made diabetic with aloxan and randomly divided into 5 groups. Group I consisted of diabetic rats with aquadest, group II with glibenclamide, and Group III-V were given extract of ceplikan leaves in different concentrations that were 1.6 mg, 3.2 mg, and 6.4mg, respectively. Treatment was given orally per day within 30 days. Level of blood glucose was measured in the day of 0, 3, 4, and 30. Statistical analysis used repeated measures and t-test.Result: The supply of ceplikan leaves extract could reduce level of blood glucose of diabetic rats, although the decrease was insignificant. Average diameter of wider Langerhans island occurred to the group of diabetic rats that were given extract of ceplikan leaves dosage 6.4 mg. There was no significant difference (p > 0.05) in changes of blood glucose level before and after experiment in diabetic rats. Pancreas histological description of rats showed that there was improvement as indicated by greater quantity of Langerhans Island and wider diameter of Langerhans Island.Conclusion: Ceplikan leaves was safe and efficacious, so that self-medication of DM using ceplikan leaves could be sustained through formal approach.


2018 ◽  
Vol 8 (2) ◽  
pp. 193
Author(s):  
Wilda Laila

Diabetes Mellitus (DM) causes various complications if it is not controlled properly. International Diabetes Federation (IDF, 2015) stated that the prevalence DM in 2014 were 8, 3% or equals to 387 million in the world. The objective of this research was to identify the influence of Sago (Metroxylon spp) on blood glucose levels of male white mouse (Mus musculus) with Diabetes Mellitus. This research was an experimental research with pre-test and post-test only group design, conducted from October to December 2016. The samples were twentyfive male white mice (Mus musculus) what were divided into five groups such as : negative control group was given standard diet, the positive control group was given induction of alloxan, three treatment groups (P1) 65mg/20g BW/day was given rice flour, groups (P2) 65mg/20g BW/day was given sago and P3 group was given sago 130mg/20g BW/day. The data were analyzed by Anova testing and Post Host Test testing with trust degree of 95%. The result was the blood glucose level of the mice showed that there was a significant difference with p value 0,012 on group (P2) with treatment, while in group treatment (P3), there was also significant difference with p value 0,019. It could be concluded that there was a significant difference in the average blood glucose level after the rice flour and sago treatment towards various groups.  Keyword : Sago, Rice Flour, Blood Glucose Level, and Diabetes Mellitus


1969 ◽  
Vol 11 (4) ◽  
pp. 181-184
Author(s):  
Muhammad Tariq Khan ◽  
Muhammad Ilyas ◽  
Salman Khan ◽  
Jawad Ahmad Kundi ◽  
Fariha Kifayat

Background: The rate of type II diabetic patients is increasing and results in oral manifestations. The oral surgery needsextraordinary measures in these patients.Objective: To assess the effect of anesthetic agent with 1:100,000 epinephrine and without epinephrine in the blood glucose levelof diabetic patients.Material and Methods: This was a randomized study of 60 patients having type 2 diabetes mellitus who were undergoing toothextraction. The study was double blind. 30-70years aged patients were selected. Blood glucose level was monitored 15 minutesbefore giving local anesthesia and after 20 minutes of the injection. ANOVA was used for comparison between groups.Results: No significant difference was seen in glycemic level using local anesthesia with 1:100,000 epinephrine (p=0.345). Therewas slight decrease noted in the blood glucose level of both groups.Conclusion: The use of 2% local anesthesia with 1:100,000epinephrine didn't cause hyperglycemia in diabetic patients.Keywords: Diabetes Mellitus, Local Anesthesia, Epinephrine, Tooth Extraction, Lidocaine.


2019 ◽  
Vol 10 (4) ◽  
pp. 2701-2704
Author(s):  
Tamilselvi ◽  
Nivitha ◽  
Priya ◽  
Monika

Diabetes mellitus is a serious debilitating longtime illness that grows in nearly 5% of the world’s peoples. People with this illness have a shortage of insulin or lessen capacity to use insulin; the hormone controlled blood glucose level. The study aims to assess the Karaya powder application among diabetic mellitus clients. The study was conducted in Mappedu village with 60 samples. The data was collected by using Structure interview questionnaires on Karaya powder. The result revealed that extract has significant effect increase knowledge on Karaya powder application on diabetic wound healing among diabetic clients.


2019 ◽  
Vol 16 (1) ◽  
pp. 40-46
Author(s):  
Rui Guo ◽  
Ruiqi Chen ◽  
Chao You ◽  
Lu Ma ◽  
Hao Li ◽  
...  

Background and Purpose: Hyperglycemia is reported to be associated with poor outcome in patients with spontaneous Intracerebral Hemorrhage (ICH), but the association between blood glucose level and outcomes in Primary Intraventricular Hemorrhage (PIVH) remains unclear. We sought to identify the parameters associated with admission hyperglycemia and analyze the impact of hyperglycemia on clinical outcome in patients with PIVH. Methods: Patients admitted to Department of Neurosurgery, West China Hospital with PIVH between 2010 and 2016 were retrospectively included in our study. Clinical, radiographic, and laboratory data were collected. Univariate and multivariate logistic regression analyses were used to identify independent predictors of poor outcomes. Results: One hundred and seventy patients were included in the analysis. Mean admission blood glucose level was 7.78±2.73 mmol/L and 10 patients (5.9%) had a history of diabetes mellitus. History of diabetes mellitus (P = 0.01; Odds Ratio [OR], 9.10; 95% Confidence Interval [CI], 1.64 to 50.54) was independent predictor of admission critical hyperglycemia defined at 8.17 mmol/L. Patients with admission critical hyperglycemia poorer outcome at discharge (P < 0.001) and 90 days (P < 0.001). After adjustment, admission blood glucose was significantly associated with discharge (P = 0.01; OR, 1.30; 95% CI, 1.06 to 1.59) and 90-day poor outcomes (P = 0.03; OR, 1.27; 95% CI, 1.03 to 1.58), as well as mortality at 90 days (P = 0.005; OR, 1.41; 95% CI, 1.11 to 1.78). In addition, admission critical hyperglycemia showed significantly increased the incidence rate of pneumonia in PIVH (P = 0.02; OR, 6.04; 95% CI 1.27 to 28.80) even after adjusting for the confounders. Conclusion: Admission blood glucose after PIVH is associated with discharge and 90-day poor outcomes, as well as mortality at 90 days. Admission hyperglycemia significantly increases the incidence rate of pneumonia in PIVH.


2017 ◽  
Vol 158 (11) ◽  
pp. 409-417
Author(s):  
Kornél Simon ◽  
István Wittmann

Abstract: In clinical recommendations the normalized blood glucose level is declared as the main target in therapy of diabetes mellitus, i.e. the achievement of euglycemia is the main therapeutic goal. This approach suggests, that the normal blood glucose value is the marker of the normal carbohydrate metabolism (eumetabolism), and vice versa: hyperglycemia is associated with abnormal metabolism (dysmetabolism). However the question arises, whether identical blood glucose values do reflect the same intracellular biochemical mechanisms? On the basis of data published in the literature authors try to answer these questions by studying the relations between the short/longterm blood glucose level and the cellular metabolism in different clinical settings characterized by divergent pathophysiological parameters. The correlations between blood glucose level and cellular metabolism in development of micro-, and macroangiopathy, in the breakthrough phenomenon, as well as during administration of metabolic promoters, the discrepancies of relation between blood glucose values and cellular metabolism in type 1, and type 2 diabetes mellitus, furthermore association between blood glucose value and myocardial metabolism in acute and chronic stress were analyzed. Authors conclude, that the actual blood glucose values reveal the actual cellular metabolism in a very variable manner: neither euglycemia does mandatorily indicate eumetabolism (balance of cellular energy production), nor hyperglycemia is necessarily a marker of abnormal metabolic state (dept of cellular energy production). Moreover, at the same actual blood glucose level both the metabolic efficacy of the same organ may sharply vary, and the intracellular biochemical machinery could also be very different. In case of the very same longterm blood glucose level the metabolic state of the different organs could be very variable: some organs show an energetically balanced metabolism, while others produce a significant deficit. These inconsistencies between blood glucose level and cellular metabolism can be explained by the fact, that blood glucose value is a transport parameter, reflecting the actual steady state of glucose transport from the carbohydrate pools into the blood, and that from the blood into the tissues. Without knowing the speed of these transports of opposite direction, the blood glucose value per se can not reveal the quantitative and qualitative characteristics of cellular metabolism. Orv. Hetil., 2017, 158(11), 409–417.


2015 ◽  
Vol 11 (1) ◽  
pp. 30
Author(s):  
Vivek K. Bajpai ◽  
Irfan A. Rather ◽  
Gyeong-Jun Nam

<p>Although several naturally available drugs have been historically used for the treatment of diabetes mellitus throughout the world, few of them have been validated by scientific criteria. Before approval of any drug developed it should pass through animal trial prior to clinical human trial, which should followed by some standard ethical rules. Recently, a large diversity of animal models have been developed to better understand the pathogenesis of diabetes mellitus, and new drugs have been introduced in the market to treat this autoimmune disease. In the present article, we demonstrated some standard handling procedure of animal trial for the approval of anti-diabetic drug, which could be helpful for both academics and industrial scientific community to conduct the animal experiments. This research also contributes in the field of ethnopharmacology to design new strategies for the development of novel drugs to treat this serious condition of diabetes mellitus that constitutes a global public health.</p><p> </p><p><strong>VIDEO CLIPS</strong></p><p><a href="https://www.youtube.com/v/_Qz4opKbNuc">Handling and caring of mice:</a>                                              2 min 30 sec</p><p><a href="https://www.youtube.com/v/1ftT8ozWy-c">Inducing diabetes in mice and observing blood glucose level:</a>   1 min 47 sec</p><p><a href="https://www.youtube.com/v/u01ls9p6310">Drug administration and observation of blood glucose level:</a>    2 min 11 sec</p><p> </p>


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