scholarly journals Personal and Perceived Depression Stigma in Individuals Affected by Depression and Relatives: Results of a Survey among Attendees of a German Depression Congress

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Heinz I ◽  
◽  
Mergl R ◽  
Allgaier A K ◽  
Hegerl U ◽  
...  
Keyword(s):  
Help Seeking ◽  
Total Sample ◽  
Depression Care ◽  
Personal Stigma ◽  
Gender And Age ◽  
Stigmatizing Attitudes ◽  
Male Patients ◽  
Sum Scores ◽  
Study Participants ◽  
Post Hoc

Background: Depression stigma is a clinically relevant factor negatively affecting the help-seeking process and depression care. Relatives of individuals suffering from depression play an important role in service utilization and in depression treatment, but little is known about their depression stigma compared to the stigma of individuals affected. Aims: We investigated whether individuals with depression, relatives and individuals being both - affected and relative - differ in depression stigma. Methods: Paper-pencil questionnaire data of 216 study participants from a German depression congress in 2017 were analyzed using Kruskal-Wallis tests to investigate subgroup differences and Mann-Whitney-U tests for post-hoc comparisons. Ordinal logistic generalized regression models with the dependent variables being the stigma sum scores and the independent variables “group”, “gender” and “age” were computed. Results: Participants being a relative of an individual with depression, being affected by depression or being both - relative and affected - reported comparable personal and perceived depression stigma. There was a statistical trend for group differences in personal stigma in the total sample, due to significantly lower personal stigma in male participants being affected by depression compared to male participants having a family member affected. Conclusions: Relatives of individuals with depression appear to have similar stigmatizing attitudes as affected individuals themselves. Potential differences in personal stigma in male relatives compared to male patients require further research, since they have implications for anti-stigma activities as well as for depression care.

Predictors of Purchasing a Hearing Aid After an Evaluation Period: A Prospective Study in Dutch Older Hearing Aid Candidates

2019 ◽  
Vol 28 (3S) ◽  
pp. 802-805 ◽  
Author(s):  
Marieke Pronk ◽  
Janine F. J. Meijerink ◽  
Sophia E. Kramer ◽  
Martijn W. Heymans ◽  
Jana Besser
Keyword(s):  
Help Seeking ◽  
Hearing Aid ◽  
Model Performance ◽  
Area Under The Curve ◽  
Secondary Data ◽  
Support Program ◽  
Evaluation Period ◽  
A Prospective Study ◽  
Study Participants ◽  
Baseline Covariates

Purpose The current study aimed to identify factors that distinguish between older (50+ years) hearing aid (HA) candidates who do and do not purchase HAs after having gone through an HA evaluation period (HAEP). Method Secondary data analysis of the SUpport PRogram trial was performed ( n = 267 older, 1st-time HA candidates). All SUpport PRogram participants started an HAEP shortly after study enrollment. Decision to purchase an HA by the end of the HAEP was the outcome of interest of the current study. Participants' baseline covariates (22 in total) were included as candidate predictors. Multivariable logistic regression modeling (backward selection and reclassification tables) was used. Results Of all candidate predictors, only pure-tone average (average of 1, 2, and 4 kHz) hearing loss emerged as a significant predictor (odds ratio = 1.03, 95% confidence interval [1.03, 1.17]). Model performance was weak (Nagelkerke R 2 = .04, area under the curve = 0.61). Conclusions These data suggest that, once HA candidates have decided to enter an HAEP, factors measured early in the help-seeking journey do not predict well who will and will not purchase an HA. Instead, factors that act during the HAEP may hold this predictive value. This should be examined.

Analysis of the involvement of single nucleotide polymorphisms of redox-homeostasis genes in the development of isolated and comorbid cardioand cerebrovascular diseases

2020 ◽  
pp. 37-49
Author(s):  
О.Ю. Бушуева
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Redox Homeostasis ◽  
Total Sample ◽  
Cerebrovascular Diseases ◽  
Cerebral Stroke ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Gender And Age ◽  
Additive Regression Model ◽  
Additive Regression

Распространенные и зачастую сочетающиеся кардио- и цереброваскулярные заболевания (КЦВЗ), включающие артериальную гипертензию (АГ), ишемическую болезнь сердца (ИБС) и мозговой инсульт (МИ), представляют собой основную причину смертности во всем мире. Окислительный стресс имеет множество патологических эффектов на сосудистый гомеостаз и в настоящее время рассматривается как один из общих механизмов развития КЦВЗ. Целью исследования было изучение ассоциации однонуклеотидных полиморфизмов генов редокс-гомеостаза rs2070424 SOD1, rs4880 SOD2, rs769214 CAT, rs713041 GPX4, rs41303970 GCLM, rs17883901 GCLC, rs854560 PON1, rs7493 PON2, rs1695 GSTP1, rs2266782 FMO3 с развитием изолированных и сочетанных форм КЦВЗ. Материалом для исследования послужила выборка неродственных индивидов славянского происхождения, общей численностью 2702 человека. В исследование вошли 1815 пациентов с различными кардио- и цереброваскулярными заболеваниями и их сочетаниями: с изолированной АГ (иАГ), с изолированной ишемической болезнью сердца (иИБС), с сочетанием АГ и ИБС (АГ+ИБС), с мозговым инсультом (МИ) на фоне АГ (АГ+МИ); с коморбидной кардио- и цереброваскулярной патологией (АГ+ИБС+МИ). Из общей выборки здоровых лиц (N=887) были сформированы 5 контрольных групп, соответствующих по полу и возрасту каждой из групп нозологических форм заболеваний. Генотипирование SNP проводили методом ПЦР в режиме реального времени путем дискриминации аллелей с помощью TaqMan-зондов. Для анализа ассоциаций генотипов с развитием заболеваний пользовались лог-аддитивной регрессионной моделью. Все расчеты выполнены относительно минорного аллеля; введены поправки на пол и возраст. SNP rs1695 GSTP1 был связан исключительно с развитием иАГ (OR=1,19, 95%CI=1,01-1,39, р=0,034). SNP rs7493 PON2 был связан с развитием всех исследованных коморбидных кардио- и цереброваскулярных заболеваний: АГ+ИБС (adjOR=1,32, adj95%CI=1,07-1,63, adjp=0,01); АГ+МИ (adjOR=1,79, adj95%CI=1,45-2,21, adjp<0,0001); АГ+ИБС+МИ (adjOR=1,51, adj95%CI=1,09-2,09, adjp=0,01), а также с укорочением протромбинового времени (adjDifference=-0,35; adjp=0,01). SNP rs2266782 FMO3 был связан с фенотипом АГ+МИ (adjOR=1,24, adj95%CI=1,02-1,51, adjp=0,03), а также снижал возраст манифестации МИ (adjDifference=-2,31; adjp=0,03). Таким образом, установлено, что однонуклеотидные полиморфизмы генов редокс-гомеостаза могут представлять важную генетическую компоненту формирования дифференцированности кардио- и цереброваскулярных фенотипов. Common and often comorbid cardio- and cerebrovascular diseases (CCVD), including arterial hypertension (AH), coronary heart disease (CHD), and cerebral stroke (CS), are the leading cause of death worldwide. Oxidative stress has many pathological effects on vascular homeostasis and is currently regarded as one of the common mechanisms for the development of CCVD. The aim of our study was to investigate the association of single nucleotide polymorphisms of the redox-homeostasis genes rs2070424 SOD1, rs4880 SOD2, rs769214 CAT, rs713041 GPX4, rs41303970 GCLM, rs17883901 GCLC, rs854560 PON1, rs7493 PON2, rs1695 GSTP1, rs2266782 FMO3 with the development of isolated and comorbid CCVD. A total 2702 individuals of Slavic origin were included for this study. The patients group included 1815 subjects with various CCVD and their combinations: isolated AH (IAH); isolated IHD (IIHD), combination of AH and IHD (AH+IHD); combination of AH and CS (AH+CS); comorbid cardio- and cerebrovascular pathology (AH+IHD+CS). From the total sample of healthy individuals (N=887), 5 sex- and age-matched control groups were formed. Genotyping was performed using TaqMan-based PCR. To analyze the associations of genotypes with the risk of diseases, a log-additive regression model was used. All calculations were performed relative to the minor allele; corrections for gender and age have been introduced. SNP rs1695 GSTP1 was associated with IAH exclusively (OR=1.19, 95%CI=1.01-1.39, P=0.034). SNP rs7493 PON2 was associated with the development of all studied comorbid CCVD: AH+IHD (adjOR=1.32, adj95%CI=1.07-1.63, adjP=0.01); AH+CS (adjOR=1.79, adj95%CI=1.45-2.21, adjP<0.0001); AH+IHD+CS (adjOR=1.51, adj95%CI=1.09-2.09, adjP=0.01), as well as shortening of prothrombin time (adjDifference=-0.35; adjP=0.01). SNP rs2266782 FMO3 was associated with the development of AH+CS (adjOR=1.24, adj95%CI=1.02-1.51, adjP=0.03), as well as decreased age of manifestation of CS (adjDifference=-2.31; adjP=0.03). Thus, it was found that genes involved in regulation of redox-homeostasis, can represent an important genetic component in the formation of differentiation of cardio- and cerebrovascular phenotypes.

scholarly journals Utility of the Mini-Cog for Detection of Cognitive Impairment in Primary Care: Data from Two Spanish Studies

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Cristóbal Carnero-Pardo ◽  
Isabel Cruz-Orduña ◽  
Beatriz Espejo-Martínez ◽  
Carolina Martos-Aparicio ◽  
Samuel López-Alcalde ◽  
...  
Keyword(s):  
Primary Care ◽  
Cognitive Impairment ◽  
Characteristic Curve ◽  
Total Sample ◽  
Phase Iii ◽  
Kappa Index ◽  
Two Phase ◽  
Clock Drawing Test ◽  
Pooled Data ◽  
Post Hoc

Objectives. To study the utility of the Mini-Cog test for detection of patients with cognitive impairment (CI) in primary care (PC).Methods. We pooled data from two phase III studies conducted in Spain. Patients with complaints or suspicion of CI were consecutively recruited by PC physicians. The cognitive diagnosis was performed by an expert neurologist, after formal neuropsychological evaluation. The Mini-Cog score was calculatedpost hoc, and its diagnostic utility was evaluated and compared with the utility of the Mini-Mental State (MMS), the Clock Drawing Test (CDT), and the sum of the MMS and the CDT (MMS+CDT) using the area under the receiver operating characteristic curve (AUC). The best cut points were obtained on the basis of diagnostic accuracy (DA) and kappa index.Results. A total sample of 307 subjects (176 CI) was analyzed. The Mini-Cog displayed an AUC (±SE) of0.78±0.02, which was significantly inferior to the AUC of the CDT (0.84±0.02), the MMS (0.84±0.02), and theMMS+CDT(0.86±0.02). The best cut point of the Mini-Cog was 1/2 (sensitivity 0.60, specificity 0.90, DA 0.73, and kappa index0.48±0.05).Conclusions. The utility of the Mini-Cog for detection of CI in PC was very modest, clearly inferior to the MMS or the CDT. These results do not permit recommendation of the Mini-Cog in PC.

scholarly journals Prevalence of thinness, overweight and obesity among Tibetan adolescents aged 12-17 years

2021 ◽  
pp. 1-17
Author(s):  
Yunfei Zhang ◽  
Jiahong Sun ◽  
Min Zhao ◽  
Costan G. Magnussen ◽  
Xi Bo
Keyword(s):  
Sampling Method ◽  
Total Sample ◽  
Overweight And Obesity ◽  
Cluster Sampling ◽  
Cross Sectional Survey ◽  
Clear Trend ◽  
Cross Sectional ◽  
Significant Difference ◽  
Prevalence Of Obesity ◽  
Study Participants

Abstract Objective: To estimate the prevalence of thinness, overweight and obesity among Tibetan adolescents aged 12-17 years. Design: Cross-sectional survey. Setting: Shigatse city of Tibet municipality, with an average altitude of more than 4000 m. Subjects: Study participants included 2,642 adolescents aged 12-17 years selected from 6 schools using a convenient cluster sampling method. Results: The prevalence of thinness/overweight/obesity among Tibetan adolescents was 9.4%/5.4%/1.4% (China definition), 14.7%/4.4%/0.7% (IOTF definition), and 2.8%/5.7%/0.9% (WHO definition). The prevalence of thinness and overweight was significantly different between both sexes based on each of three BMI classification criteria (P <0.001). There was no significant difference in the prevalence of obesity between both sexes according to each of three BMI criteria. There was no clear trend in the prevalence of thinness across ages according to the China or IOTF definition (both P >0.05), whereas an upward trend was observed for thinness in boys according to the IOTF definition (P for trend <0.05). In contrast, the prevalence of thinness tended to decrease with increasing age in girls according to the IOTF definition, and in total sample according to the WHO definition (P for trend <0.05). Conclusions: Among Tibetan adolescents, the prevalence of overweight and obesity is relatively low, while the prevalence of thinness is high, especially in boys. These data suggest urgent attention is needed to control adolescent thinness in Tibet.

scholarly journals The Influence of Policies on the Rural Part of the Pannonian Plain, Case Study: Region of Vojvodina

2015 ◽  
Vol 62 ◽  
pp. 157-172 ◽  
Author(s):  
Tamara Lukić ◽  
Bojan Đerčan ◽  
Rastislav Stojsavljević ◽  
Milka Bubalo Živković ◽  
Ivana Penjišević ◽  
...  
Keyword(s):  
Political Engagement ◽  
Study Region ◽  
Structure Activity ◽  
Gender And Age ◽  
Pannonian Plain ◽  
The Republic ◽  
Post Hoc ◽  
E Mail ◽  
Rural Part

In this article are given the opinions by Pannonia countryside inhabitants that belong to the Republic of Serbia about some characteristics of everyday policy. The opinions are gathered by poll which was distributed by e-mail to different areas of the Province of Vojvodina. Namely, 122 participants who filled the poll correctly estimated ten stances. They were formed on the basis of the themes about which the farmers have most often discussed. Special attention was directed to differences concerning the opinion of participants of different gender and age structure, activity and political engagement. Descriptive statistics, T-test and one-factor analysis of ANOVA variance have been used for establishing the differences and were complemented by Post-hoc Tukey test. This paper could be used for improvement of connections and relationships among the politicians, policy and countryside.

scholarly journals The Mediating Role of Impulsivity and Experiential Avoidance in the Relationship between Emotion Regulation and Pornography Viewing in Married Men

2020 ◽  
Vol 8 (4) ◽  
pp. 287-296
Author(s):  
Arezoo Khaleghian ◽  
◽  
Ilnaz Sajjadian ◽  
Maryam Fatehizade ◽  
Gholamreza Manshaei ◽  
...  
Keyword(s):  
Emotion Regulation ◽  
Experiential Avoidance ◽  
Short Form ◽  
Total Sample ◽  
Mediating Role ◽  
Married Men ◽  
Positive Direct ◽  
Study Participants ◽  
The Relationship

Objective: The present study aimed to predict the tendency to Internet Pornography Viewing (IPV) in married men based on difficulty in Emotion Regulation (ER) with the mediating role of impulsivity and experiential avoidance. Methods: The study participants were recruited via advertising banners posted on some of the most popular social networking applications in Iran. A total sample of 123 married men in Isfahan City, Iran, participated in the study. The study participants completed the Pornography Craving Questionnaire (PCQ), the Short-form version of Difficulties in Emotion Regulation Scale (DERS-SF), the Acceptance and Action Questionnaire-II (AAQ-II), and Barratt Impulsiveness Scale (BIS-15) through the internet. The collected data were analyzed in SPSS using descriptive statistics (Mean±SD) and correlation tests. For analyzing the study model, the PLS-SEM technique was performed in WarpPLS. Results: The current research results indicated that difficulties in ER provided a positive direct effect on the tendency to IPV (β=0.37, P<0.01). The results also revealed that impulsivity (β=0.64, P<0.01) and experiential avoidance (β=0.71, P<0.01) played mediating roles between difficulties in ER and the tendency to IPV. The model presented a good fit with the data (AVIF=2.88, GOF=0.63, SPR=1, RSCR=1, SSR=1, NLBCDR=1). Conclusion: Difficulties in ER, impulsivity, and experiential avoidance play important roles in the tendency to IPV. Impulsivity and experiential avoidance, as two modes of ER, can mediate the relationship between difficulties in ER and the tendency to IPV; therefore, they should be taken into consideration in this regard.

scholarly journals Three-dimensional study of the orbit-related structures according to sex, age and skeletal deformities

2021 ◽  
Vol 10 (11) ◽  
pp. e77101119381
Author(s):  
Tamara Fernandes de Castro ◽  
Liogi Iwaki Filho ◽  
Amanda Lury Yamashita ◽  
Fernanda Chiguti Yamashita ◽  
Naiara Caroline Aparecido dos Santos ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Class I ◽  
Class Iii ◽  
Gamma Model ◽  
Orbital Reconstruction ◽  
Skeletal Deformities ◽  
Infraorbital Canal ◽  
Male Patients ◽  
Post Hoc ◽  
Supraorbital Foramen

Objective: This study aimed to evaluate the relations between orbit-related structures and sex, age and skeletal deformities using cone-beam computed tomography (CBCT). Methods: This retrospective study evaluated 216 consecutive CBCT scans of patients, who were divided according to: sex (male, n=105; female, n=111), age (A1: 18-32 years, n=71; A2: 33-47 years, n=78; A3: 48-62 years, n=67), and skeletal deformities (Class I, n=70; Class II, n=75; Class III, n=71). The supraorbital foramen (SOF) location, volume of orbit, optic canal (OC) and infraorbital canal (IOC) were evaluated. Results were analyzed using the Gamma model test. The Tukey-Kramer post-hoc test was used to compare the variables with three factors (p<0.05). Results: The IOC volume showed higher values for male, A3 and class I patients. The SOF location and the orbital volume also showed higher values for male patients. Regarding the volume of CO, it showed higher values ​​for male and class I patients. Conclusions: According to our results, sex has been shown to have a significant influence on orbit-related structures. Age and skeletal deformities also influenced the volume of IOC and OC. These results eventually help the clinical practice, being useful for orbital reconstruction surgeries, anthropological studies, gender identification and identification of susceptibility to pathological conditions related to sexual dimorphism.

scholarly journals Comparison of Antibacterial Efficacy of Fenugreek Seed Extract Rinse and Nigella Sativa Seed Extract Rinse against Streptococcus Mutant Colonies

2021 ◽  
pp. 79-86
Author(s):  
Nasima Iqbal ◽  
ATA UR Rehman ◽  
Syeda Amber Zaidi ◽  
Kiran Khan ◽  
Lubna Farooq ◽  
...  
Keyword(s):  
Nigella Sativa ◽  
Positive Control ◽  
Seed Extract ◽  
Control Group ◽  
Distilled Water ◽  
Post Hoc Analysis ◽  
Fenugreek Seed ◽  
Study Participants ◽  
Post Hoc ◽  
Nigella Sativa Seed

Background: Dental infections were caused by the bacterium overgrowth on the surface of the tooth, and treatment should always be set up to prevent this development.Antibiotics have long been used as a conventional antibacterial medication, but their overuse has resulted in microbes gaining resistance to many of the antibiotics, trying to make many commercialized therapeutic remedies ineffectual and resulting to infection recurrence. In this regard we aim to analyze the antibacterial activity of nigella sativa seeds’ and fenugreek seed extract rinses against S. mutans' colonies. Methodology: It was a preclinical experimental study conducted at Baqai Medical and Dental College Karachi., from January - June 2021. Calculated sample size was n = 80 Consecutive sampling technique was used. Plaque of study participants was collected on sterile strips that was transported to laboratory for culture in sterile containers.The extract of Fenugreek seed and nigella sativa seed was kept in an airtight bottle and stored in a refrigerator till usage. The extracts were diluted in distilled water in 1:4 (Extract: Distilled water). Study participants were instructed to not brush their teeth before sampling. Study participants were divided into four groups (negative control, positive control, fenugreek seed extract group and Nigella sativa group) each group had 20 participants. Diluted Fenugreek seed extract and Nigella sativa extract was given to experimental groups for rinses. Results: There was significant decrease in number of colonies in positive controls, fenugreek seed extract group and nigella sativa extract group and there was no change in number of colonies in control group. Furthermore, the analysis showed significant (p-value = 0.001) difference among the groups followed by post hoc analysis. Post hoc analysis showed no difference between positive control, fenugreek seed extract group and nigella sativa group. Conclusion: Fenugreek seed extract and Nigella Sativa seed extract showed comparable antibacterial properties. Also, the effect was found to be similar to commercially available mouth rinse.

scholarly journals Adjustment among Homosexual in Gujarat

2014 ◽  
Vol 1 (4) ◽  
Author(s):  
Mukesh B Bhatt, ◽  
Dr. S. M. Makvana
Keyword(s):  
Sex Workers ◽  
Female Sex Workers ◽  
Total Sample ◽  
Statistical Technique ◽  
Female Sex Worker ◽  
Sex Worker ◽  
Female Sex ◽  
Significant Difference ◽  
Male Patients ◽  
Level Of Significance

The present Study of adjustment among Homosexual – female sex-worker, social men and women and AIDS patient from Gujarat. Total sample of 360 people was taken according to variables. In which, 180 male and 180 female were taken. In 180 male in 60 homosexual, 60 social men and 60 AIDS male patients and female in 60 female sex workers, 60 social woman and 60 AIDS female patients From Gujarat. The sample was selected randomly. Adjustment Questionnaire Developed by D. J. Bhatt (1994) used for data collection. The collected data were analyzed by F- test statistical technique at 0.01 level of significance and 2×3×2 factorial design used. Results revealed significant difference between the male and female. There was significant difference in adjustment level found among homosexual-female sex workers, social men – women and AIDS patients.

scholarly journals A cross sectional study of epidemiological determinants correlated with prevalence of hypertension among municipal school teachers located in suburban area

2017 ◽  
Vol 4 (2) ◽  
pp. 385
Author(s):  
Parth H. Vyas ◽  
Kamaxi Bhate ◽  
Mukesh Bawa ◽  
Vikrant Pagar ◽  
Amol Kinge
Keyword(s):  
Tertiary Care ◽  
Total Sample ◽  
Urban Slum ◽  
Health Condition ◽  
Urban Life ◽  
Care Hospital ◽  
Significant Relation ◽  
School Teachers ◽  
Cross Sectional ◽  
Study Participants

Background: Hypertension is a major long-term health condition and is the leading cause of premature deaths among persons experiencing sedentary urban life style behaviors such as high calorie diet, lack of physical exercise and job stress. The objectives of the present study was to determine prevalence & various risk factors of hypertension among municipal school teachers in an urban slum.  Methods:The study area was a field practice area of tertiary care hospital in a metropolitan city. Municipal school teachers from suburban slums were the study participants. Teachers above 35 years of age and want to participate in study were included. The total sample size obtained was 220.Results: 40% of the teachers were belonged to 35-40 years of age group. 70.9% of the study participants were women. Among 220 teachers 36.4% were having normal blood pressure. 43.6% teachers were in the pre- hypertension stage, while 14.5% and 5.5% were in stage- 1 and stage- 2 hypertension. The prevalence of hypertension was 20%. In present study it was found that as the age advances chances of contracting hypertension also increases [P=0.006]. Statistically significant relation between obesity and hypertension is seen [P=0.007]. There was a significant relation between physical activity and prevalence of hypertension [P = 0.021].Conclusions:Increasing age, obesity and sedentary lifestyle are proportionally related to the development of hypertension which was statistically significant. 

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