scholarly journals Coronavirus Disease 2019: Prevention and Safety in the Dental Office

2021 ◽  
Vol 5 (1) ◽  
pp. RV1-RV10
Author(s):  
Priyanka ◽  
Sonal Priya Bhansali ◽  
Sumit Bhansali ◽  
Yagyeshwar Malhotra
Keyword(s):  
Rna Virus ◽  
Close Contact ◽  
Oral Route ◽  
Health Crisis ◽  
Public Health Crisis ◽  
Dental Office ◽  
Dental Practitioners ◽  
Essential Knowledge ◽  
Dental Professional ◽  
Dental Professionals

Coronavirus disease 2019 (COVID-19) caused by a single stranded RNA virus originating from Wuhan China has gripped the whole world and evolved rapidly into a public health crisis. SARSCoV-2 (severe acute respiratory syndrome coronavirus 2 is abundantly present in nasopharyngeal and salivary secretions of affected patients and is transmitted by droplets, surface contact, fecal-oral route and by aerosolization during procedures. The dental professionals are particularly at risk because of close contact with the patient and exposure to blood, saliva and droplets. Dental professionals must be fully aware of coronavirus spreading modalities, identification of patients with this infection, so present article introduces the essential knowledge about COVID-19 infection and provide recommended management protocols for dental practitioners based on relevant guidelines, research so that dental professional are better prepared to manage  asymptomatic, suspected, and confirmed COVID-19 patients.

scholarly journals A study on the severity and prevention measures of COVID-19 among dental professionals in clinical practice management

Work ◽  
2021 ◽  
pp. 1-7
Author(s):  
Gotam Das ◽  
Shaheen Ahmed ◽  
Abdul Razzaq Ahmed ◽  
Vineet Tirth ◽  
Soofia Jamil ◽  
...  
Keyword(s):  
Close Contact ◽  
Multivariable Analysis ◽  
Knowledge Score ◽  
P Value ◽  
Prevention Measures ◽  
Analysis Model ◽  
Total Knowledge Score ◽  
Dental Practitioners ◽  
Essential Knowledge ◽  
Dental Professionals

BACKGROUND: Medical professionals, especially dental professionals, have been adversely affected by the pandemic of COVID-19 due to an increased chance of exposure to patients because of close contact during treatments. OBJECTIVES: This study aimed to evaluate knowledge about the disease and assess ways of precautions to be taken during the pandemic. METHODS: A questionnaire was developed and registered at Google Forms. The study population included dental practitioners, working in hospitals and clinics. A total of 495 dental practitioners from 14 different countries across the world responded. Most dentists were aware of the required modifications in the management of patients. The points allotted for each correct/best answer by participants for a group of questions regarding each component (Knowledge, Perceptions, and Practices) were added/summed to generate an overall score for each of the three components. RESULTS: Both univariate and multivariate analysis employed for the evaluation of results. Moreover, the total practice score was significantly associated with gender and sector of practice. Multivariable analysis model using multiple linear regressions was formulated by including those variables which were significant at the univariate stage. Hence, the practice sector was the only variable found to be significantly associated with the total knowledge score (p-value <  0.05). Conclusion: This study, based on our experience and relevant guidelines and research, introduces essential knowledge about COVID-19 and infection in dental settings.

scholarly journals Appraisal of awareness on medical emergencies and its management among dentists in Bhubaneswar, India

2021 ◽  
pp. 193-201
Author(s):  
Ramesh Nagarajappa ◽  
Ipsita Mahapatra ◽  
Dharmashree Satyarup ◽  
Sharmistha Mohanty
Keyword(s):  
Statistical Significance ◽  
Emergency Situation ◽  
Total Sample ◽  
Chi Square ◽  
Cross Sectional ◽  
Dental Office ◽  
Dental Practitioners ◽  
Medical Emergencies ◽  
And Gender ◽  
Dental Professional

Background. Medical emergencies can be distressing for any dental professional, whether in a dental practice, hospital or other sites. Objectives. To assess the knowledge and awareness of dental practitioners towards medical emergencies and its management in Bhubaneswar. Material and Methods. In this cross-sectional investigation, a self-administered questionnaire which included demographic details and 19 questions regarding knowledge about medical emergencies, was disseminated to a random sample of 183 dentists working in their private dental clinic set up in Bhubaneswar. Chi-square test was used for statistical analysis. Results. Total sample size was 183, out of which 79 (43.17%) were males and 104 (56.83%) were females. The mean age was found out to be 30.7 ± 5.38 years. Practically 96% of the practitioners were not certain enough to deal with the emergency conditions at dental office. Around 67% had not attended any workshop on emergency training. It was amazing to observe that larger part (90%) of the experts didn't possess first aid kit at their dental office. In instances of handling emergency situation at the dental chair no statistical significance (p>0.05) with respect to age and gender was found. Conclusion. This investigation showed that hypothetically dental professionals had better knowledge on medical emergencies yet at the same time they were not equipped efficiently to manage the same at their workplace.

scholarly journals COVID-19 is a New Challenge for Dental Practitioners: Advice on Patients’ Management from Prevention of Cross Infections to Telemedicine

2020 ◽  
Vol 14 (1) ◽  
pp. 298-304 ◽  
Author(s):  
Amerigo Giudice ◽  
Francesco Bennardo ◽  
Alessandro Antonelli ◽  
Selene Barone ◽  
Leonzio Fortunato
Keyword(s):  
Healthcare Professionals ◽  
Recent Literature ◽  
Scientific Information ◽  
Relevant Information ◽  
Control Measures ◽  
Infection Control Measures ◽  
Dental Procedures ◽  
Dental Office ◽  
Dental Practitioners ◽  
Essential Knowledge

Background: The COVID-19, originated in China in December 2019, has spread worldwide pandemically. Infection control measures are especially needed for healthcare professionals who meet potentially infected patients. Objective: The authors aimed to provide general knowledge about COVID-19 disease and indications for the management of emergency dental procedures based on recent literature and experience gained. Methods: A literature search was performed to identify scientific information on COVID-19 and prevention of cross infection appropriate for the practice of dentistry. Results: The authors provided relevant information about SARS-CoV-2 virus, COVID-19 disease, and prevention of cross infections in the dental office. Furthermore, the authors described their experience and highlighted the potential of telemedicine. Conclusion: This article, based on relevant researches, guidelines and Authors’ experience in a COVID-19 Hospital, introduces essential knowledge about COVID-19 and transmission routes and provides recommended management protocols for dental practitioners.

scholarly journals Monoclonal antibodies for COVID-19 therapy and SARS-CoV-2 detection

2022 ◽  
Vol 29 (1) ◽  
Author(s):  
Yu-Chyi Hwang ◽  
Ruei-Min Lu ◽  
Shih-Chieh Su ◽  
Pao-Yin Chiang ◽  
Shih-Han Ko ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Selective Pressure ◽  
Rna Virus ◽  
Severe Disease ◽  
High Specificity ◽  
Therapeutic Agents ◽  
Health Crisis ◽  
Public Health Crisis ◽  
Key Points ◽  
Major Target

AbstractThe coronavirus disease 2019 (COVID-19) pandemic is an exceptional public health crisis that demands the timely creation of new therapeutics and viral detection. Owing to their high specificity and reliability, monoclonal antibodies (mAbs) have emerged as powerful tools to treat and detect numerous diseases. Hence, many researchers have begun to urgently develop Ab-based kits for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Ab drugs for use as COVID-19 therapeutic agents. The detailed structure of the SARS-CoV-2 spike protein is known, and since this protein is key for viral infection, its receptor-binding domain (RBD) has become a major target for therapeutic Ab development. Because SARS-CoV-2 is an RNA virus with a high mutation rate, especially under the selective pressure of aggressively deployed prophylactic vaccines and neutralizing Abs, the use of Ab cocktails is expected to be an important strategy for effective COVID-19 treatment. Moreover, SARS-CoV-2 infection may stimulate an overactive immune response, resulting in a cytokine storm that drives severe disease progression. Abs to combat cytokine storms have also been under intense development as treatments for COVID-19. In addition to their use as drugs, Abs are currently being utilized in SARS-CoV-2 detection tests, including antigen and immunoglobulin tests. Such Ab-based detection tests are crucial surveillance tools that can be used to prevent the spread of COVID-19. Herein, we highlight some key points regarding mAb-based detection tests and treatments for the COVID-19 pandemic.

Restorative dental treatment in times of COVID-19

2020 ◽  
Vol 68 ◽  
Author(s):  
Robson de Lima GOMES ◽  
Marlus da Silva PEDROSA ◽  
Claudio Heliomar Vicente da SILVA
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Dental Treatment ◽  
Close Contact ◽  
Cross Contamination ◽  
Clinical Protocols ◽  
Know How ◽  
Dental Procedures ◽  
Dental Staff ◽  
Dental Professional ◽  
Restrictive Measures

ABSTRACT Since the outbreak of the Coronavirus Disease 2019 (COVID-19), caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), numerous restrictive measures have been adopted by governments of different countries. The return to elective dental care in Brazil is a reality even during the COVID-19 pandemic. During restorative dental procedures, the dental professional requires close contact with the patient, being exposed to contaminated saliva and fluids. In addition, transmission of COVID-19 by the generation of aerosol produced by dental handipieces may be possible. Thus, the dental staff must know how to act during restorative dental procedures, putting into practice the correct clinical protocols to avoid cross-contamination and COVID-19 spread. The purpose of this article is to review the literature on the biosafety practices especially in the context of restorative dental procedures in times of COVID-19.

Molecular characterization of SARS-CoV-2

2020 ◽  
Vol 20 ◽  
Author(s):  
Miribane Dërmaku-Sopjani ◽  
Mentor Sopjani
Keyword(s):  
Public Health ◽  
Drug Targets ◽  
Virus Genome ◽  
Health Crisis ◽  
Public Health Crisis ◽  
Therapeutic Drugs ◽  
New Public Health ◽  
New Public ◽  
And Function

Abstract:: The coronavirus disease 2019 (COVID-19) is currently a new public health crisis threatening the world. This pandemic disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus has been reported to be originated in bats and by yet unknown intermediary animals were transmitted to humans in China 2019. The SARSCoV- 2 spreads faster than its two ancestors the SARS-CoV and Middle East respiratory syndrome coronavirus (MERSCoV) but has reduced fatality. At present, the SARS-CoV-2 has caused about a 1.16 million of deaths with more than 43.4 million confirmed cases worldwide, resulting in a serious threat to public health globally with yet uncertain impact. The disease is transmitted by inhalation or direct contact with an infected person. The incubation period ranges from 1 to 14 days. COVID-19 is accompanied by various symptoms, including cough, fatigue. In most people the disease is mild, but in some other people, such as in elderly and people with chronic diseases, it may progress from pneumonia to a multi-organ dysfunction. Many people are reported asymptomatic. The virus genome is sequenced, but new variants are reported. Numerous biochemical aspects of its structure and function are revealed. To date, no clinically approved vaccines and/or specific therapeutic drugs are available to prevent or treat the COVID-19. However, there are reported intensive researches on the SARSCoV- 2 to potentially identify vaccines and/or drug targets, which may help to overcome the disease. In this review, we discuss recent advances in understanding the molecular structure of SARS-CoV-2 and its biochemical characteristics.

Preparation and Antitubercular Activities of Palindromic Hydrazinecarbothioamides and Carbonothioic Dihydrazides

2019 ◽  
Vol 16 (11) ◽  
pp. 1202-1210 ◽  
Author(s):  
Michael Joseps Hearn ◽  
Gwendolyn Towers ◽  
Michael Henry Cynamon
Keyword(s):  
High Resolution Mass Spectrometry ◽  
Virulent Strain ◽  
Chemotherapeutic Agents ◽  
Disc Diffusion ◽  
Global Public Health ◽  
Health Crisis ◽  
Chemical Structures ◽  
Public Health Crisis ◽  
Zones Of Inhibition ◽  
Diffusion Assay

Background:With approximately one-third of the world’s population infected, tuberculosis continues to be a global public health crisis. The rise of strains that are unusually virulent or highly resistant to current drugs is a cause of special concern, prompting research into new classes of compounds, as well as the re-evaluation of known chemotherapeutic agents.Objectives:The antimycobacterial activities associated with some recently-reported thiocarbonyl compounds kindled our interest in the synthesis of substituted hydrazinecarbothioamides (3) and carbonothioic dihydrazides (4), with the aim of investigating their potential in antitubercular drug design and discovery.Methods:In the present study, the title compounds 3 and 4 were prepared by the condensation of hydrazines with isothiocyanates in reactions readily controlled by stoichiometry, temperature and solvent. The compounds were assessed against Mycobacterium bovis BCG in Kirby-Bauer disc diffusion, and minimum inhibitory concentrations were determined against the virulent strain M. tuberculosis Erdman.Results:The chemical structures of these thermally stable compounds were determined by IR, 1HNMR, 13C-NMR, high-resolution mass spectrometry and elemental analysis. In the Kirby-Bauer disc diffusion assay, some of the compounds showed substantial diameters of inhibition against BCG. In some cases, the zones of inhibition were so large that no growth at all was observed on the assay plates. Against M. tuberculosis Erdman, several of the compounds showed significant activities. Compound 3h was the most active, demonstrating a minimum inhibitory concentration of 0.5 µg/mL.Conclusion:We found that the title compounds may be prepared conveniently in excellent purity and good yields. They are readily identified on the basis of their characteristic spectra. Some members of this class showed significant activities against mycobacteria. We conclude that further work will be warranted in exploring the antitubercular properties of these compounds.

Anticipating on a post covid-19 world and the pivotal role of science and technology

Coronaviruses ◽  
2020 ◽  
Vol 01 ◽  
Author(s):  
Saeed Khan ◽  
Tusha Sharma ◽  
Basu Dev Banerjee ◽  
Scotty Branch ◽  
Shea Harrelson
Keyword(s):  
Public Health ◽  
Pivotal Role ◽  
Public Healthcare ◽  
Healthcare Organizations ◽  
Health Crisis ◽  
Outbreak Management ◽  
The Public ◽  
Public Health Crisis ◽  
Future Outbreak

: Currently, Coronavirus disease 2019 (COVID-19) has transformed into a severe public health crisis and wreaking havoc worldwide. The ongoing pandemic has exposed the public healthcare system's weaknesses and highlighted the urgent need for investments in scientific programs and policies. A comprehensive program utilizing the science and technologydriven strategies combined with well-resourced healthcare organizations appears to be essential for current and future outbreak management.

Communications and Politics

2018 ◽  
Author(s):  
Joshua M. Sharfstein
Keyword(s):  
Public Health ◽  
Disease Control ◽  
Accurate Information ◽  
Political Judgment ◽  
Political Leaders ◽  
Health Crisis ◽  
Public Health Crisis ◽  
Control And Prevention ◽  
Public Health Officials ◽  
Centers For Disease Control

An effective communications approach starts with a basic dictum set forth by the Centers for Disease Control and Prevention: “Be first, be right, be credible.” Agencies must establish themselves as vital sources of accurate information to maintain the public’s trust. At the same time, public health officials must recognize that communications play out in the context of ideological debates, electoral rivalries, and other political considerations. During a public health crisis, this means that health officials often need to constructively engage political leaders in communications and management. Navigating these waters in the middle of a crisis can be treacherous. Figuring out the best way to engage elected leaders is a core aspect of political judgment.

The Public Health Crisis Survival Guide

2018 ◽  
Author(s):  
Joshua M. Sharfstein
Keyword(s):  
Public Health ◽  
Police Officers ◽  
Health Agency ◽  
Health Improvement ◽  
Strong Response ◽  
Popular Imagination ◽  
Health Crisis ◽  
The Public ◽  
Public Health Crisis ◽  
Critical Skills

Firefighters fight fires. Police officers race to crime scenes, sirens blaring. And health officials? Health officials respond to crises. There are infectious disease crises, budget crises, environmental health crises, human resources crises—and many more. At such critical moments, what happens next really matters. A strong response can generate greater credibility and authority for a health agency and its leadership, while a bungled response can lead to humiliation and even resignation. Health officials must be able to manage and communicate effectively as emotions run high, communities become engaged, politicians lean in, and journalists circle. In popular imagination, leaders intuitively rise to the challenge of a crisis: Either they have what it takes or they do not. In fact, preparation is invaluable, and critical skills can be learned and practiced. Students and health officials alike can prepare not only to avoid catastrophe during crises, but to take advantage of new opportunities for health improvement. The Public Health Crisis Survival Guide provides historical perspective, managerial insight, and strategic guidance to help health officials at all levels not just survive but thrive in the most challenging of times.

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