scholarly journals Analysis of the malignant ovarian tumors incidence in the Sumy region in 2014-2018.

Morphologia ◽  
2021 ◽  
Vol 15 (1) ◽  
pp. 73-78
Author(s):  
R.A. Chyzhma ◽  
A.P. Nykolenko ◽  
A.M. Piddubnyi ◽  
R.A. Moskalenko
Keyword(s):  
Ovarian Cancer ◽  
Incidence Rates ◽  
Ovarian Adenocarcinoma ◽  
Female Population ◽  
Cancer Prevalence ◽  
Breast And Cervical Cancer ◽  
Incidence And Mortality ◽  
Third Stage ◽  
High Incidence ◽  
High Incidence Rate

Background. Ovarian cancer is a very important pathology of the female reproductive system and tends to increase in incidence and mortality rates around the world. Despite the fact that ovarian cancer prevalence is lower than that of breast and cervical cancer, its mortality rate is three times higher. Aim. To analyze the incidence of ovarian cancer in the female population of Ukraine and the Sumy region in 2014–2018. Methods. Data from the National Cancer Register of Ukraine were used for this work. A statistical analysis of the incidence rates of ovarian cancer in the population of Ukraine and Sumy region was carried out. Results. The highest incidence of ovarian cancer in the Sumy region was detected in 2018 (12.5 cases per 100,000 women), and the lowest - in 2017 (10.4 cases per 100,000 women). This pathology occurs most often in women 60-79 years old. 91% of the tumors were epithelial-stromal tumors, of which 75% were serous ovarian adenocarcinomas. Ovarian cancer in most cases was diagnosed at the third stage of the disease (47% of cases), which indicates a low level of early diagnosis of this tumor. Conclusion. In the Sumy region, a high incidence rate of ovarian cancer was revealed, which exceeds the national one and has a significant age dependence. Serous ovarian adenocarcinoma is the most common type of ovarian cancer. This pathology is diagnosed mainly at the 3rd stage.

scholarly journals Importance of Screening Colonoscopy for Colorectal Cancer among Inflammatory Bowel Disease Patients in Qatar

2020 ◽  
Vol 5 (4) ◽  
Keyword(s):  
Colorectal Cancer ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Colorectal Adenocarcinoma ◽  
Screening Colonoscopy ◽  
International Guidelines ◽  
Incidence And Mortality ◽  
High Incidence ◽  
High Incidence Rate ◽  
Inflammatory Bowel

Since 1920, inflammatory bowel disease (IBD) has been linked to increased incidence and mortality from colorectal adenocarcinoma (CRC). Several studies have found that screening colonoscopy reduced CRC mortality and improved survival in IBD patients. However, there are little or no data about the prevalence of CRC/Dysplasia in Qatar detected by screening colonoscopy and weather the Qatar gastroenterologists adhere to the international guidelines. Thus, the focus of the present study was to examine the rate of CRC and dysplasia in IBD patients who underwent a screening colonoscopy. The sample consisted of 153 patients who were diagnosed and treated for IBD. The results of the study showed high incidence rate of CRC/Dysplasia among IBD patients and it was also found that the gastroenterologists in Qatar did not strictly adhere to the international guidelines in relation to the time of first screening colonoscopy of IBD patients.

scholarly journals Epidemiological trends of women’s cancers from 1990 to 2019 at the global, regional, and national levels: a population-based study

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Ming Yi ◽  
Tianye Li ◽  
Mengke Niu ◽  
Suxia Luo ◽  
Qian Chu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Ovarian Cancer ◽  
Cervical Cancer ◽  
Uterine Cancer ◽  
Female Breast Cancer ◽  
Incidence Rates ◽  
Cross Sectional ◽  
Geographical Variations ◽  
Female Breast ◽  
Incidence And Mortality

Abstract Background Every year around the world, more than 2 million women are diagnosed with breast cancer and genital tract cancers. However, there are rare studies comprehensively describing the global and regional trends of incidence and mortality of women’s cancers. Methods To study the burden and trend of women’s cancers, we conducted this cross-sectional study based on the epidemiologic data of Global Burden of Disease 2019. In this study, female patients with breast cancer, cervical cancer, ovarian cancer, and uterine cancer worldwide from 1990 to 2019 were involved. The incidence, death, and disability-adjusted life-year (DALY) were used to measure the outcomes of women’s cancers. The estimated annual percentage change (EAPC) was calculated to assess the changing trend of cancer burden. Results Among the four women’s cancers, the burden of female breast cancer was highest. During the past 30 years, the incidence, death, and DALY of female breast cancer kept increasing worldwide. In most regions especially developing countries, cervical cancer was the second most common women’s cancer. At the same time, ovarian cancer and uterine cancer occurred less frequently. Generally, the age-standardized incidence rates (ASIRs) of breast cancer, ovarian cancer, and uterine cancer were positively correlated to sociodemographic index (SDI) value. In contrast, the ASIR of cervical cancer was negatively correlated to SDI value. Conclusions Our study indicates that the incidence and mortality of women’s cancers have geographical variations and change along with SDI value. The results might be helpful to policy-makers to allocate healthy resources to control women’s cancers.

scholarly journals Cervical cancer in women of the Republic of Buryatia (morbidity and mortality compared in subjects of the Siberian Federal District and in Russia as a whole)

2021 ◽  
Vol 67 (2) ◽  
pp. 227-232
Author(s):  
Tat`yana Chimitdorzhieva
Keyword(s):  
Cervical Cancer ◽  
Incidence Rate ◽  
Federal District ◽  
Morbidity And Mortality ◽  
Siberian Federal District ◽  
Female Population ◽  
Irkutsk Region ◽  
High Incidence ◽  
High Incidence Rate ◽  
The Republic

Analysis of the morbidity and mortality dynamics of the female population of cervical cancer (CC) of the Siberian Federal District (SFO) as a whole, as well as by its individual subjects for 18 years, from 2000 to 2017. It showed a steady increase in the incidence of this form of cancer (an increase of 37.3%) and a decrease in mortality (a decrease of 11.7%) in the region as a whole and in all its subjects in comparison with those in the Russian Federation (RF). The steadily high incidence rate of cervical cancer during the period analyzed was recorded in Buryatia - 23.1 ± 1.9, after the Trans-Baikal Territory - 29.6 ± 1.7; and the Republic of Tyva - 27.7 ± 2.3; in the neighboring Irkutsk region - 19.3 ± 0.7 cases per standardized 100 thousand population, the lowest - in Kemerovo - 12.8 ± 0.5 and Novosibirsk region - 12.2 ± 0.3 regions. The consistently high incidence rate of cervical cancer during the analyzed period was recorded in the Trans-Baikal Territory - 29.6 ± 1.7; in the Republics of Tyva - 27.7 ± 2.3 and Buryatia - 23.1 ± 1.9, in the Irkutsk region - 19.3 ± 0.7 cases per standardized 100 thousand people, the lowest - in Kemerovo - 12.8 ± 0.5 and Novosibirsk - 12.2 ± 0.3 regions.The Siberian Federal District leads among other regions of Russia in the incidence of cervical cancer in women (especially in Transbaikalia, Tuva, Buryatia and Irkutsk): from 2000 to 2017, theincidence in the region increased 1.4 times with a forecast of further growth, while mortality rates indicate a positive trend - stabilization of the process. In these territories, the carcinogenic situation is determined by the interaction of a complex of various subsystems comprising it: natural, industrial, and social. Key words: cervical cancer; incidence rate; Siberian Federal District.  

scholarly journals Ovarian Cancer in Morocco: Diagnosis and Outcome

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 43s-43s
Author(s):  
A. Haimer ◽  
F. Habib ◽  
A. Soulaymani ◽  
A. Mokhtari ◽  
H. Hami
Keyword(s):  
Ovarian Cancer ◽  
Malignant Tumors ◽  
Population Based ◽  
Cancer Death ◽  
Screening Programs ◽  
The Third ◽  
Breast And Cervical Cancer ◽  
Common Cancer ◽  
Incidence And Mortality ◽  
Oncology Center

Background: Ovarian cancer is the fifth most common cancer and the fourth leading cause of cancer death among women in northern Africa, with an estimated 5050 new cancer cases and 3509 deaths from cancer in 2012 ( GLOBOCAN 2012 ). Aim: This study was conducted to determine the epidemiologic characteristics of ovarian cancer in Morocco. Methods: This is a descriptive retrospective study of ovarian cancer cases, diagnosed and treated at Al Azhar Oncology Center in Rabat between 2005 and 2015. Results: There were 164 new cases of ovarian cancer diagnosed at Al Azhar Oncology Center, accounting for 3.5% of all cancers affecting women reported during 2005-2015. During this period, ovarian cancer was the third most common cancer and the third leading cause of cancer death after breast and cervical cancer among women. The average age at diagnosis of ovarian cancer was 52.5 ± 13.3 years (range 18-81 years). The risk of developing the disease is associated with age, 91.1% of cases were diagnosed in women aged 35 years and older, with 70.2% of new ovarian cancer cases occurring among those aged 35-64 years. A 43-year-old woman was diagnosed with metastatic disease. Among all detected cases, 18 (11%) died during the study period, accounting for 6.6% of all female cancer deaths. Conclusion: Ovarian cancer is a preventable disease, and a significant decrease in incidence and mortality can be expected as a result of population-based screening programs, which rely on regular preventive examinations to search for precancerous changes and to prevent the development of malignant tumors.

scholarly journals Genetically associated breast cancer. Prevention and treatment

2019 ◽  
pp. 3-9
Author(s):  
А.Д. Зикиряходжаев ◽  
Э.К. Сарибекян ◽  
А.С. Сухотько ◽  
А.В. Трегубова
Keyword(s):  
Breast Cancer ◽  
Ovarian Cancer ◽  
Cumulative Risk ◽  
Brca2 Gene ◽  
Contralateral Breast ◽  
Malignant Neoplasms ◽  
Female Population ◽  
Increased Risk ◽  
Incidence And Mortality ◽  
Brca1 Brca2

Рак молочной железы (РМЖ) занимает первое место в структуре онкологической заболеваемости и смертности от злокачественных новообразований среди женского населения Российской Федерации. Согласно последним статистическим данным, отмечается неуклонный рост заболеваемости РМЖ, что требует более тщательного изучения возможных мер профилактики его развития. Одним из современных методов обследования при подозрении на РМЖ является выполнение генетического исследования на наличие мутаций, увеличивающих риски развития заболевания. Так, на сегодняшний день известно большое количество генов, ассоциированных с повышенным риском развития РМЖ, к таким генам относятся: BRCA1, BRCA2, CHEK2, TP53, STK-11 и многие другие. При выявлении той или иной мутации у пациентки повышаются риски развития РМЖ, а если заболевание уже реализовано, то риски развития рака контрлатеральной молочной железы. По данным литературы, кумулятивный риск развития РМЖ у носителей мутации в гене BRCA1 к 80 годам составляет 72%, при этом риск развития рака яичников составляет 44% и 40% риск развития рака контралатеральной молочной железы. Для носителей мутации в гене BRCA2 кумулятивный риск развития РМЖ составляет 69%, риск развития рака яичников составляет 17% и 26% риск развития рака контралатеральной молочной железы. Учитывая значительное повышение рисков развития РМЖ при носительстве мутации в том или ином гене, актуальным, на сегодняшний день, является вопрос о внедрении в широкую практику профилактических операций, которые позволяют значительно снизить риски развития РМЖ. В данном обзоре литературы представлены наиболее актуальные статьи, затрагивающие данную тематику. Breast cancer (BC) occupies the first place in the structure of cancer incidence and mortality from malignant neoplasms among the female population of the Russian Federation. According to the latest statistics, there has been a steady increase in the incidence of breast cancer, which requires a more thorough study of possible measures to prevent its development. One of the modern methods of examination for suspected breast cancer is to carry out a genetic study for mutations that increase the risk of developing breast cancer compared with a group of patients with sporadic breast cancer. So, today a large number of genes are known that are associated with an increased risk of developing breast cancer, these genes include: BRCA1, BRCA2, CHEK2, TP53, STK-11 etc. If one or another mutation is detected in a patient, the risks of developing breast cancer increase, and if the disease has already been realized, then the risks of developing cancer of the contralateral breast. Thus, the cumulative risk of developing breast cancer in carriers of mutations in the BRCA1 gene to 80 years old is 72%, while the risk of developing ovarian cancer is 44% and 40% the risk of developing cancer of the contralateral breast. For carriers of mutations in the BRCA2 gene, the cumulative risk of developing breast cancer is 69%, the risk of developing ovarian cancer is 17% and 26% is the risk of developing cancer of the contralateral breast. Given the significant increase in the risks of developing breast cancer with carriage of a mutation in a particular gene, today, the urgent issue is the introduction of preventive surgery into widespread practice, since it is the implementation of preventive mastectomy that can significantly reduce the risks of developing breast cancer. This literature review presents the most relevant articles affecting this topic.

scholarly journals Breast cancer incidence rates in women exposed to occupational ionizing radiation

2021 ◽  
Vol 65 (3) ◽  
pp. 245-250
Author(s):  
Anna V. Rumyantseva ◽  
Tamara V. Azizova ◽  
Mariya V. Bannikova ◽  
Ol’ga V. Zubkova
Keyword(s):  
Breast Cancer ◽  
Ionizing Radiation ◽  
Incidence Rate ◽  
Incidence Rates ◽  
Study Cohort ◽  
Female Population ◽  
Study Objective ◽  
Incidence And Mortality ◽  
Increasing Trend

Introduction. Breast cancer (BC) is one of the most common malignancies within female incidence and mortality patterns in the RF. Study objective. To analyze BC incidence in females exposed to occupational ionizing radiation over prolonged periods. Materials and methods. The study cohort included 5689 females who had been occupationally exposed to ionizing radiation throughout 1948-1982 and followed up until 31.12.2018. Results. BC was on the top of the list among females of the study cohort (11.9%). BC prevalence rate in the female cohort understudy was 28.3% as of 31.12.2018. The standardized BrCa incidence rate was 0.88 ± 0.07 per 1000 person-years of the follow-up. The absolute BrCa case increase in the females was 1.29, with the rise of 232.48% by the end of the follow-up due to the rise in age categories of females and the elevating risk of the disease occurrence. Discussion. The study cohort of females demonstrated standardized BrCa incidence rates consistent with the corresponding estimates for the general female population of the RF. Meanwhile, the observed rates were lower than those estimated for the female population of the Chelyabinsk region. The increasing trend of the standardized BC incidence rate by the end of the follow-up period (31.12.2018) was consistent with WHO statistics. The extended follow-up for an updated assessment of ionizing radiation effect on BC incidence is required to develop new cancer prevention strategies. Conclusion. The study demonstrated that BC incidence rates in the study cohort varied by age and calendar period of the follow-up. The increasing trend of the standardized rates of BC incidence was observed by the end of the follow-up.

scholarly journals Lung Cancer Patient Description in Immanuel Hospital Bandung from January 2013 to December 2014

2017 ◽  
Vol 1 (6) ◽  
Author(s):  
Ida AKT Bulan ◽  
Hana Ratnawati ◽  
Teresa L Wargasetia
Keyword(s):  
Lung Cancer ◽  
Clinical Features ◽  
Medical Records ◽  
Data Retrieval ◽  
Common Site ◽  
Cancer Prevalence ◽  
Lung Cancer Patients ◽  
Incidence And Mortality ◽  
High Incidence ◽  
Mortality Percentage

Lung cancer is a disease which has high incidence and mortality rate. It makes lung cancer become one of the biggest public health problems. The aim of this study is to find out the description of lung cancer patients in Immanuel Hospital Bandung from January 2013 to December 2014 based on the prevalence, gender, age, clinical features, metastasis, and mortality percentage. The method design was a descriptive retrospective method with data retrieval and collection of patient medical records that have been diagnosed with lung cancer in Immanuel Hospital Bandung from January 2013 to December 2014 period. This study showed that lung cancer prevalence was 51 patients, the majority of patients were males compared to females with the ratio of 2.7:1, the most common age group was 61–70 years old, the most common clinical features were dyspnea and cough, the most common site of metastasis was liver, and the mortality percentage was 33.33%.Keywords: Immanuel hospital Bandung, lung cancer, patient’s description

scholarly journals Introduction of Radiotherapy in Suriname: Impact on the Treatment of Cervical Cancer

2016 ◽  
Vol 2 (3_suppl) ◽  
pp. 49s-49s
Author(s):  
E.T.M. Dams ◽  
W.B. Hawkins ◽  
M.Y. Lichtveld
Keyword(s):  
Cervical Cancer ◽  
Conflicts Of Interest ◽  
Invasive Cervical Cancer ◽  
Incidence Rates ◽  
Female Population ◽  
Stage Disease ◽  
Incidence And Mortality ◽  
Important Health ◽  
Detection Strategies

Abstract 7 Background: Cervical cancer is the second most frequent cancer and is the leading cause of cancer-related death in Surinamese women. Radiotherapy is an essential part of treatment, but until recently was not available in Suriname. Previously, affected women were treated abroad. This study evaluated the effect of the introduction of radiotherapy in 2012 on treatment coverage and quality of care. Methods: A retrospective cohort study was conducted, comparing treatment of women diagnosed with cervical cancer in the period 2008-2011, prior to introduction of radiotherapy, to treatment of women diagnosed in the period 2012-2013, who received radiotherapy locally. Results: During the study period January 2008–December 2013, 339 women received a first diagnosis of cervical cancer, corresponding to an average annual incidence rate of 21.3 ± 1.7 per 100,000 female population, with no significant changes during the study period. More than 80% of the women presented with late-stage disease. Creoles and indigenous women showed much higher incidence rates than the other ethnic groups. The proportion of women receiving appropriate radiotherapy increased from 71.6% in the period 2008-2011 to 82.4% in 2012-2013. The waiting time between diagnosis and treatment diminished with 38 days on average. In addition, the percentage women with a delay of >150 days decreased from 29% to 7%. Conclusion: Cervical cancer continues to pose an important health problem for women in Suriname. The introduction of radiotherapy has demonstrated improved treatment of invasive cervical cancer. However, additional prevention and early detection strategies are needed to lower incidence and mortality rates. AUTHORS' DISCLOSURES OF POTENTIAL CONFLICTS OF INTEREST: No COIs from the authors.

scholarly journals Rural-urban Health Disparities for Cardiovascular Disease in the Republic of Kazakhstan

2021 ◽  
Vol 9 (E) ◽  
pp. 1331-1337
Author(s):  
Gulbarshyn Mukasheva ◽  
Tolkyn Bulegenov ◽  
Vladimir Kolyado ◽  
Altynai Kazyeva
Keyword(s):  
Myocardial Infarction ◽  
Cardiovascular Disease ◽  
Acute Myocardial Infarction ◽  
Urban Health ◽  
Rural Areas ◽  
Incidence Rates ◽  
Incidence And Mortality ◽  
High Incidence ◽  
East Kazakhstan ◽  
The Republic

BACKGROUND: An important global public health problem in many economically developed countries, in particular Kazakhstan, is the leading cause of incidence of and mortality from cardiovascular disease (CVD). AIM: The purpose of our study was to compare incidence and mortality from CVD in urban and rural areas of the Republic of Kazakhstan in 2019 based on statistics. METHODS: We conducted a descriptive study, which based on secondary data from the statistical reports on the Republic of Kazakhstan «Health of the Republic of Kazakhstan and the activities of health care organizations». Information from this database were generated by 14 provinces, three cities of republican significance and whole Kazakhstan. In addition, these indicators were divided for rural and urban settlements. RESULTS: Data from our epidemiological study of the incidence of and mortality from cardiovascular disease (CVD) in all provinces indicate a relatively high incidence of and mortality from CVD among urban population of the Republic of Kazakhstan. Among urban residents (per 100,000 population), the highest incidence rates of CVD was in Akmola province (3771.7), the ischemic heart disease (IHD) was in Almaty city (850.8), arterial hypertension (AH) was in Akmola province (2623.8), acute myocardial infarction was in the North Kazakhstan province (212.9), the highest mortality from CVD was in Karaganda province (365), the IHD was in East Kazakhstan province (135.4). Among rural residents (per 100,000 population), there are high incidence rates of CVD in the East Kazakhstan province (3452.8), the IHD in Zhambyl province (713.1), AH in the East Kazakhstan province (1871.4), acute myocardial infarction in Atyrau province (148.3), the highest mortality from CVD was in East Kazakhstan province (201.9), and the IHD also in East Kazakhstan province (77.3). CONCLUSIONS: There is rural-urban health inequality in many countries and CVD is not the exclusion. In the Republic of Kazakhstan, the rural population has got lower rates of incidence and mortality. This may be due to the bad access to medical facilities that are typical for rural areas of Kazakhstan and the shortage of modern diagnostic equipment which may interfere with timely diagnosis.

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