scholarly journals Analisis Penggunaan Antibiotik pada Pasien Sepsis Neonatus di RSUD Arifin Ahmad Provinsi Riau

2018 ◽  
Vol 11 (2) ◽  
pp. 12
Author(s):  
Nazardi Oyong ◽  
Inayah Inayah ◽  
Yuni Novita ◽  
Rizki Giofani

Sepsis that is commonly caused by bacterial infection may cause death in neonates. The appropiate antibioticadministered will increase the life expectancy of neonates with sepsis. Objective of this study was to know the patternof antibiotic use and appropriateness of antibiotic use based on sensitivity test. The study used observational methodwith cross sectional design. The collected data were retrospective. The study population were neonates with sepsis inperinatal ward from Januari – December 2014. The criteria of inclusion were positive blood culture with sensitivity testsand use of antibiotics. The percentage of particular antibiotics used in neonates with sepsis before sensitivity testwere amikacin 64,3%; meropenem 62,9% and piperazine/tazobactam 50% with suitability of 27,1%. However, aftersensitivity test there were meropenem 38,6%, amikacin 30%, vancomycin 14,3% and piperaciline/tazobactam 14,3%with appropriateness of 64,3%. The most number of antibiotic used before and after sensitivity test were amikacin andmeropenem, respectively. There was a suitability enhancement between the use of antibiotics and sensitivity testresults.

Author(s):  
Edmundo Cabezas – Heredia Et.al

The purpose of this study was to determine the relationship between coping strategies and stress in the workers of the Food Company "ARSAICO" of the Canton Chambo - Ecuador. The study population is 20 workers that is the entire company, sociodemographic variables are considered for the study, this research is quantitative approach, descriptive type with non-experimental correlational and cross-sectional design. The tests applied were the COPE questionnaire for coping and WHO - ILO for stress. For the information processing, the statistical program SPSS version 24 and the Spearman correlation coefficient were used, finding a significant inverse relationship between stress and coping. Regarding the analysis between before and after the program, positive psychology decreases stress levels from medium to low with high coping.


2018 ◽  
Vol 2 (1) ◽  
pp. 113
Author(s):  
Deni Era Nugrahaeni

Background: The incidence of malnutrition in underfives is still high. The lack knowledge and attitude of mother about balance nutrient for child can affect the way child’s feeding. Though, the nutritional status of underfives is one of the indicators in health development in Indonesia.Objective: The aim of this study is to analyze the difference of knowledge and attitude on mother before and after health education with nutrition flipchart. This is to know how the effectiveness of helath education with flipchart on the prevention of underfives malnutrition.Methods: This was an observational study with analitical and cross-sectional design because the study was conducted over a period of time. Study population were 81 mother. The sample size was determined by Lemeshow formula and simple random sampling and 67 mother were obtained. Data were collected by measuring knowledge and attitude before and after health education.Results: Statistical result showed that p values (0.000) < α (0.05). The result showed that was level of knowledge and attitude increased. Good knowledge level increased from 16 people (23.9%) to 39 people (58.2%). Good attitude inreased from 14 people (20.9%) to 36 people (53.7%).Conclusion: There were difference on the result of mother’s knowledge and attitude before and after health education with nutrition flipchart.ABSTRAKLatar Belakang: Angka kejadian gizi kurang pada balita masih tinggi. Pengetahuan dan sikap ibu yang rendah mengenai penyedian menu seimbang untuk balita dapat berpengaruh terhadap pemberian makanan anak balita. Padahal status gizi balita merupakan salah satu indikator dalam pembangunan kesehatan di Indonesia.Tujuan: Tujuan dari penelitian ini adalah untuk menganalisis perbedaan pengetahuan dan sikap ibu balita sebelum dan sesudah penyuluhan kesehatan dengan media lembar balik gizi. Hal tersebut untuk melihat bagaimana efektivitas penyuluhan kesehatan dengan media lembar balik terhadap pencegahan balita gizi kurang.Metode: Penelitian ini bersifat observational dengan desain analitik dan cross-sectional karena penelitian dilakukan pada periode waktu tertentu. Populasi penelitian adalah sebanyak 81 ibu balita. Besar sampel ditentukan dengan rumus Lemeshow dan metode simple random sampling sehingga diperoleh 67 sampel. Data didapatkan melalui penilaian pengetahuan dan sikap sebelum dan sesudah penyuluhan kesehatan.Hasil: Hasil uji statistika menunjukkan nilai p value (0,000) > α (0,05). Hasil penilaian menunjukkan bahwa terdapat peningkatan tingkat pengetahuan dan sikap ibu balita. Ibu dengan tingkat pendidikan baik meningkat dari 16 ibu (23,9%) naik menjadi 39 ibu (58,2%). Ibu dengan sikap baik meningkat dari 14 ibu (20,9%) menjadi 36 orang (53,7%).Kesimpulan: Terdapat perbedaan tingkat pengetahuan dan sikap ibu balita sebelum dan sesudah penyuluhan dengan media lembar balik gizi.


2016 ◽  
Vol 1 (1) ◽  
pp. 21-30
Author(s):  
Imelda Derang

Intelligence is the ability to apply the knowledge and experiences that have been gained into the effort tasks are challenging and flexible book. Behaviour is an action that involves aspects of affective, cognitive, and psychomotor. Goal: This study aims to determine the relationship between the behavior of student nurses intelligence level II STIKes Santa Elisabeth Medan. Method: This study uses correlation with cross sectional design. The study population was all students / i Ners Level II STIKes Santa Elisabeth Medan as 65. The samples used were 65 respondents, the sampling technique in this research is using purposive sampling. The instrument of this study using questionnaire and observation sheets by using product moment test person. Result: Intelligence students as many as 30 people (46.2%) classified as having an average level of intelligence. A total of 32 people (49.2%) classified as well-behaved students. Person product moment test results obtained p value = 0.172 where a significant level of p> 0.05 so that this value proves that the absence of a relationship between the behavior of student nurses intelligence level II STIKes Santa Elisabeth Medan. Conclusion: Recommended for institutions, motivating students in balancing the behavior and intelligence. 


2018 ◽  
Vol 3 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Linze F. Hamilton ◽  
Helen E. Gillett ◽  
Adam Smith-Collins ◽  
Jonathan W. Davis

Background: In neonatal intensive care, coagulase-negative Staphylococcus species can be both blood culture contaminants and pathogens. False-positive cultures can result in clinical uncertainty and unnecessary antibiotic use. Objective: This study sought to assess whether a sterile blood culture collection bundle would reduce the incidence of false-positive blood cultures in a regional neonatal intensive care unit. Method: Clinical data was collected from all infants who had blood cultures taken before and after the introduction of the sterile blood culture collection bundle intervention. This intervention required 2% chlorhexidine and full sterile precautions for blood culture collection. False-positive blood culture rates (presence of skin commensals and ≥3 clinical infection signs) were compared before and after the intervention. The number of days of unnecessary antibiotics associated with false-positive blood cultures was also analysed. Results: In the pre-intervention group (PRE) 197 cultures were taken from 161 babies. In the post-intervention group (POST) 170 cultures from 133 babies were acquired. Baseline demographics were similar in both groups. The rate of false-positive cultures in the PRE group versus the POST group was 9/197 (4.6%) compared to 1/170 (0.6%) (p < 0.05). Unnecessary antibiotic exposure was reduced in the PRE group in comparison to the POST group (27 vs. 0 days, p < 0.01). Conclusions: Implementation of sterile blood culture collection intervention reduced the number of false-positive results. This has potential benefit in reducing unnecessary antibiotic use.


2011 ◽  
Vol 35 (6) ◽  
pp. 206-212 ◽  
Author(s):  
Maja Meerten ◽  
Julia Bland ◽  
Samantha R. Gross ◽  
Antony I. Garelick

Aims and methodOur aim was to follow-up on a cohort of self-referred doctors who attended MedNet. We used a two-point cross-sectional design. Measures included three standardised self-report questionnaires administered before and after consultation. Doctors were also asked to complete a service user questionnaire, and data regarding engagement and onward referrals were gathered through case-note review.ResultsA statistically significant improvement in scores on all three questionnaires was found after intervention; however, scores on one subscale, the risk domain of the Clinical Outcomes in Routine Evaluation – Outcome Measure, did not change significantly. Of the doctors at no risk of suicide at intake, nearly two-thirds (n = 41/70, 59%) were sufficiently helped by the consultations provided to not need further treatment. Of the doctors at some risk of suicide at intake, two-thirds (n = 34/51, 67%) did need an onward referral. Only one doctor required hospital admission, an outcome that suggests the approach used is containing and clinically responsive.Clinical implicationsThis paper highlights the efficacy, need and importance of specialist services for doctors in difficulty. We found that the bespoke consultation model provided at MedNet is valued highly by the doctors as service users.


2020 ◽  
Vol 21 (1) ◽  
pp. 36-39
Author(s):  
Syahrastani Syahrastani ◽  
Argantos Argantos ◽  
Siska Alicia Farma

The situation of lack of oxygen supply to cells and tissues is often not realized by many people (hypoxia). Hypoxia can occur in various situations in life. The main effect of hypoxia is the effect on the brain, so the body will do everything it can to restore the state of homeostasis. HIF-1α protein is a marker of hypoxic conditions. HIF-1α regulates the synthesis of many genes to maintain and restore body homeostasis from hypoxia to normoxia. This study was a descriptive study with cross-sectional design. The sample of this study were six swimming athletes with a 12-19 year age range who met the inclusion and exclusion criteria. The HIF-1α protein is measured by the ELISA method. Data were analyzed statistically. The results showed higher levels of HIF-1α after anaerobic exercise than the levels of HIF-1α before and after aerobic exercise. This is greatly influenced by the intensity of the exercise carried out. This proves that cellular adaptation to hypoxia is more stable in aerobic exercise, where the body's metabolism during aerobic exercise is more stable  


2020 ◽  
Vol 10 (4) ◽  
pp. 31452.1-31452.10
Author(s):  
Haleh Talaie ◽  
◽  
Maryam Nazari ◽  
Habib Emami ◽  
◽  
...  

Background: Sepsis is one of the significant causes of mortality in hospitalized patients. This cross-sectional study was performed to determine the frequency of positive blood culture and assess sepsis criteria based on Third International Consensus Definitions (related to Sequential Organ Failure Assessment score) and clinical and paraclinical findings (i.e., on-admission leukocytosis, increased lactate level, and fever) in poisoned patients admitted to the Toxicological Intensive Care Unit (TICU). Methods: Medical records of a total of 2000 poisoned patients admitted to the TICU of Loghman Hakim Hospital from 2016 to 2018 were assessed. Among them, 189 cases (9.45%) with suspected sepsis were considered eligible to be enrolled in the study. Results: Of 189 cases, 146 (77.24%) had possible signs and symptoms of sepsis as well as SOFA score higher than two with positive blood culture in 81 cases (55%). The Mean±SD serum level of lactate was 25.97±16.32 on admission. The most common pathogen detected in blood culture was coagulase-negative Staphylococci in 35 (24.0%) out of 146 cases. Glasgow Coma Scale (GCS) less than 12, age older than 50 years, and bilirubin more than 1.2 mg/dL were found as independent predictors of sepsis on multivariate analysis. Conclusion: Based on our findings, it is proposed that the sepsis definition should not be restricted to the guidelines. The patients’ poisoning background and presence of many confounding factors, including poisoning-induced on-admission increased lactate levels, leukocytosis, and disturbed arterial blood gas provide a critical decision-making situation to confirm sepsis according to guidelines.


2019 ◽  
Author(s):  
ADEM KOSE

Abstract Background Irrational antibiotic use can adversely affect treatment outcomes or even lead to increased antimicrobial resistance. We aimed to determine antimicrobial prescribing habits and to evaluate the level of theoretical knowledge of rational antibiotic use and awareness about antimicrobial resistance among the senior students of medical faculty and the family physicians in Malatya province in Turkey. Methods This study was cross-sectional research and was carried out between dates of 01 February-30 April 2019, in Malatya province. Power analysis was calculated as minimum 240 participants when considering a proportion difference of 0.18 between the groups, a type I error of 0.05 and a type II error of 0.20. A total 225 senior students in Inonu University Medical Faculty (Group 1) and 230 actively-working family physicians in Malatya primary healthcare services who were found eligible (Group 2) were included in to this study. A questionnaire form was prepared including seven sections and thirty questions. All of the participants were interviewed face to face. Before the questions, the purpose of the study and the contents of the questions were explained to participants. Qualitative data were analyzed by Pearson chi-square test. A p<0.05 value was considered to be statistically significant. Results The group 1 had a tendency to apply to specialist physician when starting to themselves antibiotic treatment, they were more cautious when making antibiotic decision, and their theoretical knowledge level was better. They argued that penal sanctions could be more effective by developing strict use policies to raise awareness of resistance to antibiotics. The group 2 had higher self-confidence and it was also concluded that forgot their theoretical antibiotic knowledge over time and could not follow the novel information because of the intensity of working life. Both groups stated that post-graduation trainings could be used effectively for reducing the antibiotic resistance. Conclusion This study highlighted the need for immediate action of training and corrective actions and might create awareness to determine the difference in theoretical knowledge levels and behavior models of physicians before and after graduation and to reduce higher use rates to lower levels. Key words: Antimicrobial resistance, antibiotic, awareness, rational use


Author(s):  
Gisela Pineda-García ◽  
Estefanía Ochoa-Ruiz ◽  
Gilda Gómez-Peresmitré ◽  
Silvia Platas-Acevedo

The objective of this study is to assess the effect of alcohol consumption, anxiety, and food restriction before and after consuming alcohol and body image on the risk of anorexia and bulimia in college students from Tijuana, Baja California, through predictive statistical models. A quantitative, descriptive, and cross-sectional design and a non-probabilistic sample of 526 college students from Tijuana, Baja California, México were used. Application of the scales (with acceptable psychometric properties) was conducted in classrooms. Through path analyses, four models were found with adequate indicators of goodness of fit: (1) risk of anorexia in women [Chi Square (X2) = 5.34, p = 0.376, Adjusted Determination Coefficient (R2)= 0.250]; (2) anorexia risk for men (X2 = 13.067, p = 0.192, R2 = 0.058); (3) risk of bulimia in women (X2 = 3.358, p = 0.645, R2 = 0.202); and bulimia risk for men (X2 = 14.256, p = 0.075, R2 = 0.284). The findings provide empirical evidence for the food and alcohol disturbance model.


2018 ◽  
Vol 20 (4) ◽  
pp. 230-243 ◽  
Author(s):  
Hanne Berthelsen ◽  
Tuija Muhonen ◽  
Susanna Toivanen

PurposeThere is an increased interest for introducing activity-based offices at universities. The purpose of this study is to contribute to the knowledge about the importance of the built environment for the psychosocial work environment within academia by analyzing how staff at a large Swedish university experienced the physical and psychosocial work environment before and after moving to activity-based offices.Design/methodology/approachA Web-based survey was distributed to all employees at two faculties at a university three months before (2015,n= 217, response rate 51 per cent) and nine months after (2016,n= 200, response rate 47 per cent) relocation to a new activity-based university building.FindingsIn the new premises, a vast majority (86 per cent) always occupied the same place when possible, and worked also more often from home. The social community at work had declined and social support from colleagues and supervisors was perceived to have decreased. The participants reported a lower job satisfaction after the relocation and were more likely to seek new jobs. No aspects in the physical or psychosocial work environment were found to have improved after the relocation.Research/limitations implicationsThe study had a two-wave cross-sectional design, which does not allow establishing causal relations.Practical implicationsThere is reason to be cautious about relocation to activity-based offices at universities. The potential savings in costs for premises may lead to may be followed by an increase in other costs. The risk that staff cannot concentrate on their work in activity-based university workplaces and lose their sense of community with colleagues are factors, which in the long run may lead to decreased efficiency, more conflicts and poorer well-being.Originality/valueThis paper contributes with new knowledge concerning changes in the physical and psychosocial work environment when relocating from cell offices to activity-based offices in a university setting.


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