scholarly journals LIPID ALTERATION

2011 ◽  
Vol 18 (04) ◽  
pp. 663-666
Author(s):  
KAMAL ELDIN AHMED ABDELSALAM ◽  
MANAHIL ALI SHARWANI ◽  
SHAZA SALIH TAHA
Keyword(s):  
Lipid Profile ◽  
Cross Sectional Study ◽  
Control Group ◽  
P Value ◽  
Diabetic Patients ◽  
Obese Patients ◽  
Sectional Study ◽  
Cross Sectional ◽  
Obese Subjects ◽  
Males And Females

Objective: determine serum lipid profile in diabetic and obese non-diabetic patients. Materials: 300 subjects comprising three groups, the first group included 100 diabetic patients (non-obese) with duration of diabetes over 5 years, the second group (obese) included 100 obese subjects (non-diabetic) with duration of obesity over 5 years, and the third group (control) included 100 healthy subjects. Methods: Lipid profile on the serum was performed with an auto analyzer using standard methods. Study design and period: Prospective Analytical Cross Sectional Study conducted in period from September 2006 to January 2008. Results: A significant (p value<0.05) increase in lipid profile results of diabetic and obese patients comparing to control while HDL-C showed significant decreasing. The cholesterol is significantly increased in females than males in diabetic patients, while the triglycerides are significantly decreased in diabetic females. The parameters showed insignificant variations between males and females in obese patients. Conclusions: In comparison to control group, DM & obese groups showed significantly increase in TG, TC, and LDL-C, but significantly decrease in HDL-C. Females showed significant increasing in TC and significant decreasing in DM group, while in obese group females showed insignificant decreasing in TG and TC. 

scholarly journals Do Males and Females Differ in Terms of Their KAP Regarding Halal Pharmaceuticals?

2014 ◽  
Vol 3 (3) ◽  
pp. 163
Author(s):  
Saleha Sadeeqa ◽  
Azmi Sarriff
Keyword(s):  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Male And Female ◽  
Males And Females

<p><strong></strong>There is an increasing awareness amongst Muslim consumers to avoid all items containing  non-Halal ingredients including medications. Male and female are different both biologically and psychologically, it therefore, needed for a study to compare KAP of males and females regarding  Halal pharmaceuticals. Methods<strong>:</strong>This was a cross-sectional study using a structured , self-administered questionnaires to compare the knowledge, attitude &amp; perception regarding Halal pharmaceuticals, among males and females in Penang state of Malaysia. Results<strong> </strong>revealed that there is no significance difference in the knowledge, attitude and perception of males and females. This is concluded that males and females are equally aware and have same attitude and perception regarding Halal pharmaceuticals. P value of .05 or less was taken as statistically significant.</p>

Frequency of Dyslipidemia in Obese

2021 ◽  
Vol 15 (10) ◽  
pp. 2831-2832
Author(s):  
Ambreen Asif ◽  
Kashif Aziz Ahmad ◽  
Sohaib Akbar ◽  
Talha Munir
Keyword(s):  
Body Mass Index ◽  
Lipid Profile ◽  
Body Mass ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Obese Subjects

Objective: frequency of dyslipidemia in obese subjects Methodology: In this was a cross sectional study, we included a total of 100 cases, between 30 and 70 years of age of either gender having body mass index >30 whereas we excluded all those cases who were already taking treatment of dyslipidemia. A fasting blood sample was followed for lipid profile from the hospital lab and results were followed for presence/absence of dyslipidemia. Results: In this trial, mean age was 44.57+8.52 years. Mean lipid profile was recorded as 210.17+36.73 total cholesterol, 178.83+12.10 triglycerides, 133.55+9.74 LDL and 34.42+6.58 HDL. Mean Body mass index was calculated as 34.11+7.25. Frequency of dyslipidemia in obese subjects was recorded as 51%(n=51) Conclusion: We concluded that frequency of dyslipidemia is higher in obese subjects coming to a tertiary care hospital Lahore. So, it is recommended that every patient who present with obesity, should be sort out for dyslipidemia. However, it is also required that every setup should have their surveillance in order to know the frequency of the problem Keywords: Obese, dyslipidemia, frequency

scholarly journals Perbedaan Profil Lipid pada Akseptor Depo Medroksi Progesteron Asetat dengan Implant Levonorgestrel di Wilayah Kerja Puskesmas Air Tawar Padang Tahun 2014

2015 ◽  
Vol 4 (1) ◽  
Author(s):  
Rafika Oktova ◽  
Desmiwarti Desmiwarti ◽  
Arni Amir
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Medroxyprogesterone Acetate ◽  
Colorimetric Method ◽  
Cross Sectional Study ◽  
Hormonal Contraceptives ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Significant Difference

AbstrakDepo Medroksiprogesteron Asetat dan Implant Levonorgestrel merupakan kontrasepsi hormonal progestin sintetik yang memiliki efek samping yaitu peningkatan berat badan dan mempengaruhi metabolisme lipid. Tujuan penelitian ini adalah untuk mengetahui perbedaan profil lipid pada akseptor Depo Medroksiprogesteron Asetat dengan Implant Levonorgestrel. Ini adalah studi observasional dengan desain cross sectional comparative. Penelitian dilakukan di laboratorium Bagian Biokimia Fakultas Universitas Andalas dari Maret sampai Mei 2014. Subjek penelitian terdiri dari dua kelompok, masing-masing 20 subjek. Pemeriksaan dengan metode enzimatis kolorimetri yaitu GPO-PAP untuk trigliserida, dan CHOD-PAP untuk kolesterol total, HDL dan LDL. Data dianalisis menggunakan uji t dengan nilai p<0.05 dianggap bermakna secara statistik. Rerata kadar LDL pada Depo Medroksiprogesteron Asetat lebih tinggi (95,51 ± 20,47) mg/dl daripada Implant Levonorgestrel (79,35 ± 12,55) mg/dl dengan nilai p<0,05 artinya terdapat perbedaan yang bermakna sedangkan kadar trigliserida, kolesterol total dan HDL tidak bermakna. Kesimpulan penelitian in adalah terdapat perbedaan yang bermakna rerata kadar LDL pada Depo MedroksiprogesteronAsetat dan Implant Levonorgestrel, sedangkan kadar trigliserida, kolesterol total dan HDL tidak bermakna. Secara klinis profil lipid pada kedua kelompok dalam keadaan normal.Kata kunci: profil lipid, depo medroksiprogesteron asetat, implant levonorgestrelAbstractDepo Medroxyprogesterone Acetate and Levonorgestrel Implants are synthetic progestine hormonal contraceptives that have side effect in body weight and lipid metabolism. The objective of this study was to determine the differences of lipid profile between acceptors Depo Medroxyprogesterone Acetate and Levonorgestrel Implants. This was a comparative cross sectional study. The study was done at laboratory of Biochemistry Departement in Medical Faculty of Andalas University from March until May 2014. The subjects were consisted of two groups, each group had 20 subjects. The examination used an enzymatic colorimetric method GPO-PAP for trygliserides and CHOD-PAP for total cholesterol, HDL and LDL. Data was analyzed using analysis of t-test with p<0.05 was considered to be significantly different. LDL levels average in Depo Medroxyprogesterone Acetate was (95,51 ± 20,47) mg/dl and Levonorgestrel Implants was (79,35 ± 12,55) mg/dl with p-value, it means there is a significantly difference, but levels of trygliserides, total cholesterol and HDL means there is no significantly difference. This research concluded that there is a significant difference on average levels of LDL in the Depo Medroxyprogesterone Acetate and Levonorgestrel Implants but levels of trygliserides, total cholesterol and HDL there is no significantly difference. The clinically lipid profile in the two groups is in normal range.Keywords: lipid profile, depo medroxyprogesterone acetate and levonorgestrel implants

scholarly journals Comparing the Suicidal Ideation in Diabetic Patients Receiving Insulin with Oral Medication

2020 ◽  
Author(s):  
Mahboube Ahmad Nazari ◽  
Hamid Oliaee ◽  
Reza Bidaki ◽  
Mohammad Hossein Sorbi
Keyword(s):  
Suicidal Ideation ◽  
Significant Relationship ◽  
Cross Sectional Study ◽  
P Value ◽  
Diabetic Patients ◽  
Sectional Study ◽  
Cross Sectional ◽  
Medication Treatment ◽  
Patients With Diabetes ◽  
Suicidal Ideation Questionnaire

Objective: Diabetes is one of the chronic diseases which can be accompanied with suicide. The study was conducted to assess and compare the prevalence of suicidal ideation in diabetic patients receiving insulin and oralmedication treatment. Materials and Methods: In this cross-sectional study, 2000 patients with diabetes supported by diabetes institute of Rafsanjan in 2017. After giving conscious permission, the patients filled in a demographic checklist and Beck suicidal ideation questionnaire. The data were analyzed using SPSS-16. Results: Prevalence of suicidal ideation in patients with diabetes receiving insulin was 3.2% (n=32) and in people receivingoral medication treatment was 3.1% (n=31). There were no association between suicidal ideation and the method of diabetes treatment. Suicidal ideation was more prevalent in illiterate people; however, no significant relationship was seen between suicidal ideation and education level. Also, there was no significant relationship between marital status and suicidal ideation. There was no relationship between suicidal thoughts and the method of treatment ( P -value: 0.05). Conclusion: Suicidal ideation is more prevalent in diabetic patients, but there were not differences between two group under insulin therapy and oral anti-diabetic agents.

scholarly journals Relationship between sleep disturbances, lipid profile and insulin sensitivity in type 1 diabetic patients: a cross-sectional study

2020 ◽  
Author(s):  
Ana Carolina Musser Tavares de Mattos ◽  
Yuri Sofiati Campos ◽  
Vitória Oliveira Fiorini ◽  
Yasmin Sab ◽  
Bruna Landeiro Tavares ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Lipid Profile ◽  
Sleep Disturbances ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Sectional Study ◽  
Cross Sectional ◽  
Type 1 Diabetic Patients

scholarly journals Patients’ Adherence to Anti-diabetic Medications and Associated Factors in Mizan-Tepi University Teaching Hospital: A Cross-Sectional Study

2021 ◽  
Vol 58 ◽  
pp. 004695802110674
Author(s):  
Jafer Siraj ◽  
Turi Abateka ◽  
Oliyad Kebede
Keyword(s):  
Side Effects ◽  
Drug Use ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
University Teaching ◽  
P Value ◽  
Diabetic Patients ◽  
Sectional Study ◽  
Monthly Income ◽  
Cross Sectional

Introduction: A number of medications have been demonstrated to lower blood glucose. However, current-day management has failed to achieve and maintain the optimal glycemic level for diabetic patients. Patients’ non-adherence is among the most contributing factors. Therefore, the aim of this study was to explore the prevalence of non-adherence to anti-diabetic medications and associated factors. Methods: A hospital based cross-sectional study was conducted from November 2020 to January 2021. A systematic random sampling technique was used. Data were collected by structured questionnaire adapted from different literatures. Then, data were entered into SPSS version 25 and analyzed. To determine the association of dependent and independent variables, multiple logistic regression was done. P-value <.05 was considered statistically significant. Results: A total of 275 study participants were interviewed with a response rate of 100%. From this 53.8% were females, 59.3% were in the age group of 41-60 years, 35.3% were college/university graduates and 79.3% were not using social drugs. One hundred eighty-seven (68%) of them were adherent to their anti-diabetic medication. Factors found to be significantly associated with anti-diabetic medication adherence were age >60 years (AOR = .276, 95% CI = .124-.611) attending higher education (AOR = 6.203, 95% CI = 1.775-21.93), retired (AOR = 7.771, 95% CI = 1.458-41.427), housewife (AOR = 7.023, 95% CI = 1.485-33.215), average monthly income 1001birr-2000 birr (AOR = .246, 95% CI = .067-.911) and social drug use (AOR = 3.695, 95% CI = 1.599-8.542). Forgetfulness, not affording, side effects, misunderstanding of instructions, and poly-pharmacy were identified reasons for non-adherence. Conclusions and Recommendations: Patients’ adherence to anti-diabetic medications in the current study is sub-optimal. Age, monthly income, level of education, occupational status, and social drug use were associated with adherence. Forgetfulness, not affording, and side effects were reasons identified to contribute to non-adherence. Therefore, adherence counseling, use of alarms, and the way to mitigate non-affordability, including anti-diabetic medications into a program drug should be considered.

scholarly journals Ambulatory blood pressure pattern in overweight and obese subjects: a prospective, cross-sectional study

2019 ◽  
Vol 7 (6) ◽  
pp. 2168
Author(s):  
Shuchi Singh ◽  
Akash C. Lohakare
Keyword(s):  
Blood Pressure ◽  
Ambulatory Blood Pressure ◽  
Tertiary Care ◽  
Normal Subjects ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Anthropometric Parameter ◽  
Obese Subjects

Background: Obesity is widely described as a leading cause of morbidity and mortality and is a known risk factor of many cardiovascular and non-cardiovascular diseases including hypertension. The aim of this study was to analyze the pattern of ambulatory blood pressure in overweight and obese subjects.Methods: This was a prospective, cross-sectional study performed over a period of 1 year in 95 subjects attending the Department of Medicine of tertiary care teaching institute. Anthropometric measures such as weight, height, body mass index (BMI), and waist circumference (WC) were recorded. Ambulatory blood pressure monitoring over a period of 24-hrs was performed in each individual and values were recorded. Comparison between normal subjects and overweight and/or obese subjects was done in terms of various ambulatory BP parameters.Results: Based on BMI, significantly higher proportion of females were obese (p-value = 0.020), as compared to males. Based on both BMI and WC, significant proportion of overweight and obese subjects had higher 24-hr SBP (p-value < 0.001) and 24-hr DBP (p-value = 0.001); higher day-time SBP (p-value < 0.001); higher night-time SBP (p-value < 0.001); and widening of 24-hr pulse pressure (> 50 mmHg) (p-value < 0.001) as compared to normal subjects. However, among various abnormal ABPM parameters, majority of the parameters revealed more incidence of BP abnormalities with increased BMI than with increased WC. Thus, BMI appeared to be a better anthropometric parameter than WC.Conclusions: The findings of the present study confirm that obesity in apparently non-hypertensive subjects leads to rise in both SBP and DBP. Moreover, it is the systolic part of ABPM which probably predicts the cardiovascular morbidity in overweight and obese subjects.

scholarly journals Comparison of the Sex Hormones’ Serum Level in Women With Recurrent Aphthous Stomatitis and Healthy Population: A Cross-Sectional Study

2021 ◽  
Author(s):  
Fatemeh Lavaee ◽  
Zahra Ranjbar ◽  
Mina Jalalian ◽  
Mohammad Amin Amiri
Keyword(s):  
Serum Level ◽  
Sex Hormones ◽  
Cross Sectional Study ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Control Group ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Mean

Abstract Background:In this study, we aimed to evaluate the sex hormonal serum level in patients with recurrent aphthous stomatitis and compare them with healthy participants.Methods:This cross-sectional study was done on patients with recurrent aphthous stomatitis who had referred to Shiraz Dental Faculty, Oral and Maxillofacial Medicine Department during 2018-2019. The non -menopause women with recurrence of at least 3 lesions per year were enrolled in this study.The mean serum level of FSH, LH, PRL (prolactin), testosterone, DHT (Dihydrotestosterone), DHEA-S (Dehydroepiandrosterone sulfate), estradiol and progesterone of 30 participants in each group of case and control were measured and compared. The data were analyzed by SPSS version 18 and independent T-test, Mann-Whitney U test, Spearman’s correlation coefficient test, Chi-square test and Fisher’s test.Results: The mean serum level of DHEA-S in patients with recurrent aphthous stomatitis (RAS) was significantly lower than the control group (p value=0.002). In addition to DHEA-S, the mean serum level of testosterone was lower in the evaluation group although this difference was not significant (p value=0.057).Considering the effect of age on the mean serum level of sex hormones, our results revealed that only DHEA-S mean serum level was decreased by increasing the age of participants in patients with RAS (p value=0.018).The number of participants with abnormal range of testosterone (p value<0.0001) and progesterone (p value=0.037) serum level was significantly more in patients with RAS. The frequency of RAS in a year did not show a significant relationship with the serum level of the evaluated hormones.Conclusion: The patients with RAS had a lower serum level of DHEA-S. The mean serum level of testosterone and progesterone was significantly abnormal in RAS patients.

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