scholarly journals PEG TUBE

2016 ◽  
Vol 23 (02) ◽  
pp. 187-192
Author(s):  
Sajid Hussain ◽  
Kashif Ali ◽  
Hafiz Muhammad Farhan Rashid ◽  
Abrar Hussain Khosa ◽  
Aushter Abbas
Keyword(s):  
Tube Placement ◽  
Research Centre ◽  
Exclusion Criteria ◽  
Female Ratio ◽  
Peristomal Infection ◽  
Group A ◽  
Males And Females ◽  
Peg Tube ◽  
Male To Female ◽  
Trial Setting

Objectives: To determine the efficacy of Cephalexin and Co-amoxiclave inpreventing Peristomal infection after PEG tube placement in head and neck and other cancerpatients. Study Design: Prospective, randomized clinical trial. Setting: Internal MedicineDepartment Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore. Period:February 2009 to September 2009. Material and Methods: A total of 160 patients includingboth males and females were selected by Non probability purposive sampling. Patients meetinginclusion and exclusion criteria were registered in the study from outpatient department afterinformed consent. These patients were randomly assigned into two groups. Group A was startedon Cephalexin 500mg q6h Per-orally started 24 hrs before the procedure with the 4th dosegiven one hour before the procedure and continued it as q6h for five days after the procedure.Group B was given Co-amoxiclav 1G Per-orally 12 hrs before the procedure with the seconddose of 1G, one hour before the procedure and then same dose advised q12h for five daysafter PEG tube placement. Results: Male to female ratio in both groups was 2:1 with 63.3%males and 33.8% females. Patients were aged between 19-80years, divided in four age groupswith 38.8% falling in age group 50-64 years. Mean age is 52.11+-13.59 years and median age54 years. The efficacy of Cephalexin and Co-amoxiclave was 84.7% and 78.6% respectivelywith no significant statistical difference among two groups. Conclusion: We concluded thatCephalexin and Co-amoxiclave were both equally effective in preventing peristomal infection.

scholarly journals TOTAL KNEE ARTHROPLASTY?;

2017 ◽  
Vol 24 (07) ◽  
pp. 992-996
Author(s):  
Mehran Khan ◽  
Ashfaq Ahmed ◽  
Fraz Umer ◽  
Atiq uz Zaman ◽  
Saeed Ahmad ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Blood Loss ◽  
Tranexamic Acid ◽  
Knee Arthroplasty ◽  
Controlled Trial ◽  
Exclusion Criteria ◽  
Female Ratio ◽  
Total Knee ◽  
Male To Female ◽  
Trial Setting

The treatment of choice for osteoarthritic knee is Total knee arthroplasty (TKA)and the most important problem in it is the blood loss. Objectives: To compare the postoperativemean blood loss with Tranexamic acid versus control after Total Knee Arthroplasty.Study Design: Randomized controlled trial. Setting: Ghurki Trust Teaching Hospital Lahore.Period: 01 year. Methodology: 100 patients were included and divided in 2 groups, selectedby non-probability purposive sampling, fulfilling inclusion and exclusion criteria. Group T(Tranexamic) received 15mg/kg IV Tranexamic acid 10 minutes before inflating tourniquet andthe same dose intravenously 3 hours post-operatively. Group C (control) received placebo(normal saline) intravenously. Blood loss collected in a container was measured with syringe/jarafter 24 hours of surgery. Results: In group C there were 23(46%) males and 27(54%) femaleswith male to female ratio 1:1.7 with mean age of 64yrs ± 6.3 yrs. In group T there were 28(56%)males and 22 (44%) females with male to female ratio 1.2:1 with mean age of 65yrs ± 7.4 yrs.After 24 hours Mean blood loss in Group C were 694 ±151 ml with 74 % patient in range of600-900ml while Mean blood loss in Group T were 388 ml ±105 ml with 76 % patient in rangeof 300-600ml. Mean decrease in blood loss with the use of tranexamic acid { mean blood lossin T group – mean blood loss in T group } were 306 ml which were statistically significant(p<0.05) using t Test. Conclusion: Tranexamic acid is a potent anti-fibrinolytic agent and its use intotal knee arthroplasty results in decrease in post-operative blood loss thereby decreasing theneed of blood transfusion.

scholarly journals Palonosetron for the prevention of chemotherapy induced nausea and vomiting: a comparative study in a tertiary care hospital from India

2019 ◽  
Vol 8 (10) ◽  
pp. 2197
Author(s):  
Shubhatara Swamy ◽  
Vijaya Rajendran ◽  
Durga Prasan ◽  
Pratibha Nadig
Keyword(s):  
Tertiary Care ◽  
Nausea And Vomiting ◽  
Research Centre ◽  
Care Hospital ◽  
Serious Adverse Events ◽  
Female Ratio ◽  
First Line Therapy ◽  
Significant Difference ◽  
Group A ◽  
Group B

Background: Despite advances in symptom management, chemotherapy-induced nausea and vomiting (CINV) remains one of the most dreadful consequences of cancer therapy.Methods: The study was carried out at Medical Oncology Department, Vydehi Institute of Medical Sciences and Research Centre, Bangalore. Hundred and forty-four cancer patients of either sex, aged 18-65 years with adequate blood counts requiring moderately emetogenic chemotherapy (MEC) as per Hesketh classification were included. The patients were prospectively divided into two groups before the initial cycle of chemotherapy. Patients in Group A (n=71) received ondansetron, and dexamethasone along with aprepitant capsules, Whereas, Group B (n=73) received palonosetron, and dexamethasone along with placebo capsules, 30 minutes before chemotherapy. Thereafter the patients were administered with the drugs and observed for nausea and vomiting. The efficiency of both regimens was assessed by adopting validated functional living index emesis (FLIE) questionnaire. Analysis of the data was done using the SPSS 21.0 software.Results: The mean age of the patients was 40.5 years and the male to female ratio was 1:2.4. In all the patients, no changes were detected in the ECG readings after MEC. The nausea and vomiting score were comparable in both groups. No significant difference (p>0.05) was noticed between group A and group B in both mm and in FLIE points. No serious adverse events were found relating to antiemetic treatment.Conclusions: Palonosetron in combination with corticosteroids was non inferior to ondansetron in combination with aprepitant and corticosteroids in controlling acute and delayed stages of CINV in patients requiring MEC. Thus, it can be recommended as first-line therapy for patients treated with MEC.

Group structure in wood bison: nutritional and reproductive determinants

1993 ◽  
Vol 71 (7) ◽  
pp. 1367-1371 ◽  
Author(s):  
Petr E. Komers ◽  
François Messier ◽  
Cormack C. Gates
Keyword(s):  
Habitat Selection ◽  
Group Structure ◽  
Dilution Effect ◽  
Foraging Strategies ◽  
Female Ratio ◽  
Male And Female ◽  
Wood Bison ◽  
Males And Females ◽  
Mixed Groups ◽  
Male To Female

Sexual segregation in ungulates has been documented for many species including bison. However, male and female bison do not differ in their pattern of habitat selection. In the present study we observed that a fraction of bison groups did not have young (<2 years) despite the presence of males and females. The male to female ratio in these groups was 2.4. We call them adult groups, in contrast to mixed groups, where young were present and the male to female ratio was 0.4. The proportion of cows with young (mothers) in a group was negatively correlated with the male to female ratio, suggesting that mothers associated more often with other cows than with bulls. Before the rut, cows without young (non-mothers) spent less time feeding than either mothers or bulls. However, mothers and non-mothers did not differ in the number of steps per minute they took while grazing, and both types of cows stepped faster than bulls. We suggest that cows feed more selectively than bulls and that the differing foraging strategies result in temporal but not spatial segregation of the sexes. Possibly as a result of similar nutritional demands, mothers tended to aggregate, forming nursery groups. We suggest that the formation of nursery groups can also serve to protect calves through a dilution effect of predation. Whether mothers actually prefer to associate with other mothers remains to be investigated.

scholarly journals A comparative study of the effect of piroxicam versus diclofenac on wound healing in clean abdominal wounds

2018 ◽  
Vol 5 (3) ◽  
pp. 1041 ◽  
Author(s):  
Chandrashekar Reddy J. Madinur ◽  
Prashant Tubachi ◽  
Prashant Tubachi ◽  
A. S. Godhi ◽  
A. S. Godhi
Keyword(s):  
Wound Healing ◽  
Controlled Trial ◽  
Research Centre ◽  
Female Ratio ◽  
Factors Affecting ◽  
Significant Difference ◽  
Group A ◽  
One Year ◽  
Group B ◽  
The Individual

Background: The primary function of the skin is to serve as a protective barrier against the environment. The process of wound healing constitutes an array of interrelated and concomitant events. Understanding these processes and various factors affecting these processes continue to expand. The present study was undertaken to compare and evaluate the effect of piroxicam versus diclofenac on wound healing in clean abdominal wounds.Methods: The present one year randomized controlled trial was conducted on all the patients undergoing appendicectomies for uncomplicated appendicitis and uncomplicated inguinal hernia repairs in the Department of Surgery, KLES Dr. Prabhakar Kore Hospital and Medical Research Centre, Belgaum during the period of one year. Based on the thumb rule a total of 60 patients divided into two groups of 30 each were studied. Based on the computer-generated randomization patients were allocated to two groups that is group A (Inj. Piroxicam) and Group B (Inj. Diclofenac).Results: In the present study, males outnumbered females with male to female ratio between of 1.72 to 2:1. The mean age in group A was30.9±7.86 years and in group B it was 30.3±7.97 years. Both the groups that is Group A and B were graded under grade I (Good wound healing) from the POD 3 onwards. Overall the individual score and total scores had no influence of the final grading (outcome) of the wound.Conclusions: Overall, better results were seen on wound healing in patients who received Inj piroxicam with significantly less post-operative redness and edema. However, this did not have significant difference in the final outcome of the grading of the wound. 

scholarly journals TYPHOID FEVER WITH JAUNDICE

2015 ◽  
Vol 22 (04) ◽  
pp. 439-442
Author(s):  
Muhammad Usman Anjum ◽  
Hafizullah Khan ◽  
Syed Humayun Shah
Keyword(s):  
Typhoid Fever ◽  
Liver Enzymes ◽  
Systemic Infection ◽  
Liver Function Tests ◽  
Exclusion Criteria ◽  
Female Ratio ◽  
The Mean ◽  
System Disorder ◽  
Male To Female ◽  
Study Setting

Typhoid fever is a systemic infection which is caused by Samonella entericaserotype typhi. It is a multi-system disorder involving many organs including liver. Liverinvolvement could be in the form of jaundice, rise in liver enzymes or hepatomegaly. It canpresent as acute hepatitis in rare cases, called typhoid hepatitis. Objectives: This study wascarried out to study the association of typhoid fever in patients with jaundice. To determinethe frequency of typhoid fever among patients presenting with jaundice. Design: Descriptivecross sectional study Setting: at Gastroenterology Unit, Ayub Teaching Hospital, Abbottabad,Period: March 2011 to December 2011. Methods: Total 115 patients were included in thestudy based on inclusion and exclusion criteria. Typhidot IgM test was performed to confirmthe diagnosis of typhoid fever. Results: The mean age of patients was 28.5 ± 10.14 years,with 54.8% male gender predominating the overall sample. The male to female ratio was 1.2:1.Typhoid fever was found in 22 (19.1%) out of 115 patients with jaundice and there were 68.2%were males and 31.8% were females. Conclusions: Typhoid fever is not rare to present asjaundice in our part of the world where typhoid fever is endemic. Therefore, all those patientswho have fever, jaundice, abnormal liver function tests or hepatomegaly must be screened fortyphoid fever especially in areas where typhoid fever is endemic.

scholarly journals SUN-713 Prevalence of Renal Cysts in Patients with Carney Complex

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Crystal Dawn Chrysavgi Kamilaris ◽  
Athanasios Gkirgkinoudis ◽  
Christina Tatsi ◽  
Georgia Pitsava ◽  
Ninet Sinaii ◽  
...  
Keyword(s):  
Renal Cysts ◽  
Carney Complex ◽  
Regulatory Subunit ◽  
Cyst Size ◽  
Female Ratio ◽  
Renal Imaging ◽  
Younger Age ◽  
High Prevalence ◽  
Males And Females ◽  
Male To Female

Abstract In the general population renal cysts appear most commonly in patients &gt;50 y and in men. Among published studies, the prevalence of renal cysts detected by MRI was 27%, detected by CT was 20-41%, and detected by US was 4-17% (Mensel, et al., 2018; Choi, et al., 2016). In these studies, the male to female ratio in patients with renal cysts ranged from 1.4:1 to 2.93:1. Carney complex (CNC) is an autosomal dominant multiple endocrine neoplasia and lentiginosis syndrome predominantly caused by aberrant cAMP-protein kinase A (PKA) signaling mostly (but not always) due to germline inactivating defects in PRKAR1A which encodes the regulatory subunit type 1α of PKA. In a small retrospective study, 5 of 9 subjects with CNC had renal cysts on MRI or CT (Ye, et al., 2017). This same study evaluated the development of renal cysts in kidney-specific Prkar1a knockout mice, where all mice developed a renal cystic phenotype. To determine the prevalence of renal cysts, we performed a retrospective cohort study of patients with CNC evaluated at our institution between 1984 and 2019 who underwent renal imaging with MRI, CT, and/or US. We hypothesized that CNC leads to renal formation of cysts in humans, with increased number of renal cysts and earlier age at detection. 117 patients with CNC (69 female [59%], 48 male [41%]) were evaluated with renal imaging (56% MRI, 41% CT, 3% US). Of these, 39 (33%) patients had renal cysts that were first detected on imaging between the ages of 13 and 58 y (mean age at diagnosis 37.1 ±12.7 y; 5 [13%] 12-19 y, 5 [13%] 20-29 y, 10 [26%] 30-39 y, 11 [28%] 40-49 y, and 8 [21%] 50-59 y). The mean number of cysts was 1.3 ±0.7, and mean dominant cyst size was 1.2 ±0.9 cm. Average creatinine at diagnosis was 0.8 ±0.2 mg/dl. Of the patients with renal cysts, 22 were female (56% of patients with renal cysts, 32% of females with CNC that underwent renal imaging) and 17 were male (44% of patients with renal cysts, 35% of males with CNC that underwent renal imaging). There was no difference in the prevalence of renal cysts between males and females (35% vs 32%, p=.70, for a 1.1:1 ratio). Age, number, and dominant cyst size were also not different between sexes (p=.51, p=.84, and p=.26, respectively). However, creatinine levels were higher in males (0.9 ±0.1 vs 0.7 ±0.1, p&lt;.001). All 39 patients with renal cysts had defects in PRKAR1A as compared to 73 of 78 (94%) patients with CNC that did not have renal cysts on imaging (p=.17). In conclusion, our data demonstrate that there is a high prevalence of renal cysts in patients with CNC with both males and females being affected equally, in contrast to the majority of previously reported population studies. They also suggest that renal cysts may develop in patients with CNC at a younger age. These results can be further validated by comparison to a cohort of healthy controls.

scholarly journals LOWER URETERIC STONES EXPULSION;

2017 ◽  
Vol 24 (09) ◽  
pp. 1331-1335
Author(s):  
Khalid Hussain ◽  
Maria Tarique ◽  
Attiq ur Rehman Khan ◽  
Asim Bukhari ◽  
Bilal Akhter ◽  
...  
Keyword(s):  
Controlled Trial ◽  
Oral Treatment ◽  
P Value ◽  
X Rays ◽  
Female Ratio ◽  
Group A ◽  
Insignificant Difference ◽  
The Mean ◽  
Group B ◽  
Trial Setting

Objectives: To compare Tamsulosin versus ESWL for lower ureteric stonesexpulsion. Study Design: Randomized controlled trial. Setting: Outpatient Department ofUrology at Services Hospital, Lahore. Period: January 2015 to December 2015. Material& Methods: Total 50 patients were enrolled in study. Patients were divided into 2 groups.In group A, 25 patients received daily oral treatment of 0.4mg Tamsulosin for 28 days, andin group B, 25 patients were treated with ESWL. A stone-free condition, was defined as thecomplete absence of any stone based on plain abdominal X-rays observed and during followupvisits at the time of treatment of stone was noted. Results: The mean age of the patientswere recorded as 33.20±9.23 years. There were 40(80%) males and 10(20%) females with maleto female ratio of 4:1. Out of 50 patients, 16(32%) presented with hematuria, 3(6%) had feverwhile 31(62%) appeared with no complication status. Out of 50 patients, 21(42%) presentedwith expulsion time 08-14 days in which 14(28%) were from tamsulosin group and 07(14%)were from ESWL group, similarly 19(38%) patients appeared with expulsion time of 15-28 daysin which 10(20%) were from tamsulosin group and 09(18%) were from ESWL group. Statisticallythere is insignificant difference between the groups i.e. p-value=0.28 Ns. Conclusion: Thisstudy suggests that the tamsulosin helps in the earlier clearance of stone fragments andreduces the complications as compared to ESWL.

scholarly journals Intranasal Splint in Nasal Septal Surgery: Is It Necessary?

2020 ◽  
Vol 32 (2) ◽  
pp. 126-129
Author(s):  
Jahangir Alam Mazumder ◽  
Md Golam Mustafa ◽  
AHM Delwar ◽  
Shazibur Rashid ◽  
Md Mostafizur Rahaman ◽  
...  
Keyword(s):  
Complete Healing ◽  
College Hospital ◽  
Female Ratio ◽  
Medical College ◽  
Septal Surgery ◽  
Significant Difference ◽  
Group A ◽  
Medicine Today ◽  
Group B ◽  
Male To Female

Introduction: After SMR/septoplasty with or without turbinate surgery, it needs to keep apart the septum and turbinates upto their complete healing otherwise there is a chance of adhesion (synechia) formation. To prevent this there are variousprocedures. To place an intranasal splint in one or both sides of the septum is one of them. Nowadays there raised thequestion of whether the splinting is necessary or not. There is no significant difference in result with or without anintranasal splint. Weighing against the co-morbidities the routine use of an intranasal splint can no longer be justified. Materials and Methods: This is a randomized control study of 200 patients of SMR/septoplasty, done for nasal septaldeviation causing symptoms in Cumilla Medical College Hospital in the period of January 2016 to December 2019. Theywere equally divided into two groups, group-A were operated placing an intranasal splint and group-B with no intranasalsplint. They were followed up for 6 weeks to detect any synechia and co-morbidities. Result: The age of our patients wasranged from 13-49 years with a mean age of 22.45 years. The male to female ratio is 1.78:1. Synechia was found in 4% ofthe splinted group and 6 of the nonsplinted groups. Co-morbidities were detected more in the splinted group than that ofnon-splinted. In INS group these were found as follows: pain in the nose, face and head (26%), faint during removal ofnasal splint (6%), nasal obstruction (38%), the anxiety of splint removal in the postoperative period (35%) and vestibulitisdue to persistent irritation by a splint (17%). Conclusion: There is little significant advantage of using intranasal splintroutinely in septal surgery to prevent synechia formation. Medicine Today 2020 Vol.32(2): 126-129

scholarly journals Epidemiology of Colorectal Cancer in Jordan, From 2003 to 2012

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 32s-32s
Author(s):  
M. Alzaghal
Keyword(s):  
Colorectal Cancer ◽  
Public Health Problem ◽  
Newly Diagnosed ◽  
Important Public Health Problem ◽  
Policy Makers ◽  
Female Ratio ◽  
Screening Programs ◽  
Males And Females ◽  
Spss Software ◽  
Male To Female

Background: Colorectal cancer is an important public health problem. There are nearly one million new cases of colorectal cancer diagnosed world-wide each year and half a million deaths. Regionally it is the fourth most common cause of morbidity and mortality. Recent reports show that, in Jordan, it ranked the second among all new cancers in both males and females. Aim: To explore and identify the epidemiology of colorectal cancer in Jordan over the 10 years period 2003-2012 to provide update information regarding the likely future. Methods: This project was a descriptive study, cases were identified from Jordan cancer registry (JCR), all Jordanian cases diagnosed and registered in 2003-2012 were included, data on age, sex, primary site, morphology, grade and stage were collected and filtered, frequency by graphs and tables was demonstrated, SPSS software version 17 was used for analysis, and official approval to do the study was taken from the registry. Results: Total number of colorectal cancers in Jordan registered in JCR from 2003 to 2012 was 3299 cases among both genders, 1833 in males which accounted for (55.6%) and 1466 cases (44.4%) in females. In 2012, there were 567 (11.3%) of all newly diagnosed cases among Jordanians compared with 357 (10.3%) in 2003. Male to female ratio was (0.9:1) compared with (1.4:1) in 2003. The median age at diagnosis was 61 years for both genders in 2012, in 2003 it was (51). The overall age-standardized incidence rate (ASR) increased from 11/100,000 in 2003 to 16.3/100.000 in 2012. Conclusion: This study will provide health professionals researchers and policy makers with detailed information about colorectal cancer epidemiology through 2003-2012 and it demonstrate the magnitude of the problem, which will assist in planning and evaluation and to identify priorities, and this will provide a solid database for establishing screening programs for early detection.

Comparison of Phenobarbital versus Magnesium Sulphate for Management of Neonate with Birth Asphyxia

2021 ◽  
Vol 15 (8) ◽  
pp. 2145-2147
Author(s):  
Lubna Riaz ◽  
Syed Muhammad Ahmed ◽  
Muhammad Ahmad Zakki ◽  
Neelam Faryad ◽  
Shazia Iram ◽  
...  
Keyword(s):  
Magnesium Sulphate ◽  
Demographic Data ◽  
Birth Asphyxia ◽  
Female Ratio ◽  
Group A ◽  
Insignificant Difference ◽  
The Difference ◽  
Group B ◽  
Breathing Effort ◽  
Male To Female

Background: Poor breathing effort results in decrease oxygen supply to brain and other organs that lead to birth asphyxia. Phenobarbital and magnesium sulphate are both neuroprotective to asphyxia! injury to brain. Objective: To compare the frequency of neonatal mortality with phenobarbital versus magnesium sulphate in the management of birth asphyxia Study Design: Randomized control trial Place and Duration of Study: Pediatrics Department, Sheikh Zayed Hospital, from 8th March 2020 to 8th September 2020. Methodology: One hundred and two neonates were enrolled. After taking informed consent from parents their demographic data was obtained. Then patients were divided in to two groups; group A treated with Phenobarbital and other group B treated with magnesium sulphate. Results: The mean age of group A neonates was 54.37+14.303 days and in group B 48.40+15.20 days with male to female ratio was 0.7:1. Adverse outcome occurred in 12 (11.54%) patients. Statistically insignificant difference (P=0.122) was found between groups. Conclusion: There is more adverse effects outcome with magnesium sulphate than phenobarbital however the difference was statistically insignificant for management of neonates with birth asphyxia. Keywords: Birth asphyxia, Neonates, Magnesium sulphate (MgS04), Phenobarbital

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