scholarly journals Factors influencing the effectiveness of colonoscopy

2020 ◽  
Vol 1 ◽  
pp. 98-100
Author(s):  
Mustikawati Mustikawati ◽  
Sodikin Sodikin
Keyword(s):  
Logistic Regression ◽  
Drug Use ◽  
Medical History ◽  
Univariate Analysis ◽  
Current Medical ◽  
Multiple Logistic Regression ◽  
Preparation Time ◽  
Chi Square ◽  
Chi Square Test ◽  
History Of

Colonoscopy is one of the most widely-used procedures for diagnostic examination and treatment of colorectal diseases, either benign or malignant. Colonoscopy results are influenced by several factors such as current medical history, history of drug use, history of accompanying illnesses, and procedures performed. To analyze the factors which affectiverness the results of colonoscopy among the undergoing patients in Regional Public Hospital of Banyumas. The method used was observational analytic with a cross sectional approach. From the consecutive sample selection, it gave 76 respondents. The analysis was done using Univariate analysis with frequency distribution test, bivariate with chi square test and multivariate with multiple logistic regression test. Most of the respondents (51 respondents, 67.1%) aged 46-65 years and most of them were female (41 or 53.1%), they were dominated by high school graduates (56 or 73.7%), and the dominant occupation status was undemployed (31 or 40.8%). The results of the chi square test showed that there was an effect of current disease history, namely complaints / indications for colonoscopy examinations (p 0.011), drug use (p 0.021),accompanying disease history (p 0.003), and implementation procedures (p 0.000) on colonoscopy results. The results of multiple logistic regression showed that the factor that mostly influences the colonoscopy results was the length of preparation time (1-2 days of preparation).In conclusion current medical history, drug use history, accompanying medical history, and procedure administration significantly influence the colonoscopy outcome. And the most influencing factor is the length of preparation time (1-2 days of preparation).

scholarly journals Relationship Of Nutritional Components In Toddlers Aged 25-59 Months To Stunting And Short Stature Incidents In Pragaan District, Sumenep Regency

2021 ◽  
Vol 17 (1) ◽  
pp. 27-40
Author(s):  
Pertiwi Febriana Chandrawati ◽  
Conita Walida Sabrina
Keyword(s):  
Logistic Regression ◽  
Short Stature ◽  
Nutrient Intake ◽  
Iodized Salt ◽  
Chi Square ◽  
Control Approach ◽  
Nutritional Components ◽  
Chi Square Test ◽  
History Of ◽  
Relationship Of

Stunting and short stature are height per-age <-2SD for specific age and gender. The process of stunting and short stature starts from the womb until the beginning of life. The direct cause of stunting is the lack of nutritional intake in the first 1000 days of life, which can inhibit height growth. Study aimed to investigate the association between the relationship of nutritional components in toddlers to stunting and short stature incidents in Pragaan District, Sumenep Regency. Observational analytic with a case-control approach, using the Purposive-Sampling method. The research sample consisted of 76 toddlers aged 25-59 months. The statistical analysis used was the chi-square test and logistic regression test. The result of chi-square test and logistic regression for stunting on nutrient intake variable ( p = 0.000, OR = 26,3, CI 95% (4,630-153,573), history of breastfeeding (p=0,000, OR=72,6,CI95% (7,63-690,78), iodized salt (p=0,000, OR=8,5,CI 95% (1,833-39,421), FE tablet (p=0,000,OR=37,00, CI 95%(3,762-363,91). The result of chi-square test and logistic regression for short stature on nutrient intake variable (p=0.001, OR=7,2,CI 95% (2,260-23,400), history of breast feeding (p=0,007, OR=4,500,CI 95% (1,210-16,742), iodized salt (p=0,007, OR=19,125, CI 95% (5,062-72,259), FE tablet (p=0,149). There is a relationship between nutritional components intakes such as breastfeeding history and iodine salt consumption with stunting and short stature in Pragaan District, Sumenep Regency.

scholarly journals Factors Associated with Serious Injuries among Adolescents in Ghana: Findings from 2012 Global School Health Survey

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Martin Ackah ◽  
Mohammed Gazali Salifu ◽  
Hosea Boakye
Keyword(s):  
Logistic Regression ◽  
Multiple Logistic Regression Analysis ◽  
Multiple Logistic Regression ◽  
School Students ◽  
Chi Square ◽  
Chi Square Test ◽  
Amphetamine Use ◽  
School Truancy ◽  
Serious Injuries ◽  
Smoking Marijuana

Introduction. Injuries are of public health concern and the leading cause of residual disability and death among teenagers, especially in low- and middle-income countries (LMICs). In Ghana, the burden of injury among adolescents is under-reported. Hence, the study sought to determine the prevalence of serious injuries (SI) and the potential factors influencing these injuries among school children in Ghana. Methods. This study was conducted in Ghana among Junior High School (JHS) and senior high school students (SHS) using the 2012 Global School-Based Student Health Survey (GSHS) data. The GSHS employed two-stage cluster sampling method. Serious injuries (SI) and independent factors were measured via self-administered questionnaires. Pearson chi-square test between each explanatory variable and serious injuries was conducted and the level of statistical significance was set at 5%. The significant variables from the chi-square test were selected for multiple logistic regression analysis. Multiple logistic regression was performed to estimate the adjusted odds ratio (AOR) at 95% confidence interval (CI). Results. The prevalence of SI in the past 12 months was 66% [CI=61.8–70.2] . The most common cause of SI was fall, 36%. The common types of injuries were cut/stab wounds and broken/dislocated bone. In the multiple logistic regression analysis, after controlling for other variables, educational level (AOR = 0.64, CI = 0.44–0.90, p  < 0.015), suicidal ideation (AOR = 1.58, CI = 1.00–2.48, p  < 0.002), suicidal attempt (AOR = 1.88, CI = 1.29–2.72, p  < 0.001), having at least one close friend (AOR = 1.49, CI = 1.17–1.89, p  < 0.002), school truancy (AOR = 1.66, CI = 1.31–2.09, p  < 0.000), smoking marijuana (AOR = 2.64, CI = 1.22–5.69), and amphetamine use (AOR = 2.95, CI = 1.46–5.69) were independently associated with SI. Conclusion. The findings of the study established a high prevalence of SI among adolescents in Ghana, with cut/stab wound and broken/dislocated bone being the most reported type of injuries. This study also revealed that factors such as educational level, suicidal ideation, suicidal attempt, at least one close friend, school truancy, smoking marijuana, and amphetamine use are associated with SI among the adolescents. Therefore, pragmatic interventional programs should be targeted at these factors to curb the rate of SI among junior and senior school students.

scholarly journals Factors associated with drug use among adolescents

2021 ◽  
Vol 43 ◽  
pp. e14-43556
Author(s):  
Mirene Peloso ◽  
Brunnella Alcantara Chagas de Freitas ◽  
Bruno David Henriques ◽  
Samuel De Souza Magalhães Marques ◽  
Luciana Moreira Lima
Keyword(s):  
Drug Use ◽  
Family Structure ◽  
Male Gender ◽  
Chi Square ◽  
Factors Associated ◽  
Related Family ◽  
Low Education ◽  
Municipal Schools ◽  
Chi Square Test ◽  
History Of

The study aimed to identify factors associated to drug use in adolescents. For this purpose, it has been observed 133 adolescents registred in ninth grade in two municipal schools in Viçosa, who answered an individual questionnaire validated by PAHO / WHO, applied by members of the Uncensored Extension Project of the Federal University of Viçosa (UFV). Substance use and family structure were evaluated. Statistical tools were: Epi-Info 7.0 StatCalc, Pearson's chi-square test, Poisson regression and SPSS version 23.0 and Stata 9.0 programs. The sample had an average of 15 years old, that 26.3% reported drug use, thus, 65,4% related family history of drug use and low education. Other aspects of family structure included: good family perception, absence of violence and family mental disorder by 78.2%, 82.7% and 75.9% of adolescents, respectively. Only males persisted as a factor associated with drug use, with 2.4 times higher use (PR 2.39; 95% IC 1.19-4.78; p = 0.014). Therefore, only the male gender showed a higher risk for drug use, and further studies are needed to evaluate factors associated with drug use, aiming to promote public health.

HUBUNGAN ANTARA STATUS GRAVIDA DAN RIWAYAT PENYAKIT GENETIK PADA IBU HAMIL DENGAN KEJADIAN PRE-EKLAMPSIA BERAT DI RUMAH SAKIT UMUM PUSAT Dr. MOHAMMAD HOESIN PALEMBANG TAHUN 2012

2019 ◽  
Vol 3 (1) ◽  
Author(s):  
Y. Widyastuti Y. Widyastuti
Keyword(s):  
Univariate Analysis ◽  
Severe Preeclampsia ◽  
Bivariate Analysis ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Significance Level ◽  
Chi Square Test ◽  
History Of ◽  
Early Diagnose

ABSTRACT Preeclampsia is a disease with signs of hypertension, edema, and protein urine due to pregnancy. In Indonesia preeclampsia is still one of the cause of maternal death, range 1,5 % - 2,5 %. The purpose of this study is to determine the relationship between maternal disease and a history of gravida with severe preeclampsia incidience in the General Hospital Center Dr. Mohammad Hoesin Palembang in 2012. The method used in this reserch is Analytical research with Cross Sectional Design. The Population in this research is a case of delivering mothers with severe preeclampsia and control mothers with lower preeclampsia. The number of samples is 242 maternal, 181 maternal with weight preeclampsia and 61 maternal with lower preeclampsia. The data analysis conducted univariate and bivariate statistics with Chi-Square test with significance level α = 0,05. For the univariate analysis of 242 maternal, 181 mothers ( 74,8 % ) with  severe preeclampsia.which belong to the category of mother with primigravida as much as 131 people ( 72,3 % ) and maternal with history of genetic maternal illnes of 90 people ( 49,7 % ) . while the results of the bivariate analysis, Chi-square statistical test showed that there was sifnificant association between gravida status with weight preeclampsia accident where ( p value = 0,008 ) and also significant relationship between history of genetic maternal illnes with weight preeclampsia accident where ( p value = 0,012 ). We hope this research can be turn of weight preeclampsia accident Suggestion with prevention, early diagnose and prompt treatment with Antenatal Care Consistenly.   ABSTRAK  Preeklampsia adalah penyakit dengan tanda-tanda hipertensi, edema, dan protein urine akibat kehamilan. Diindonesia preeklampsia berat masih merupakan salah satu penyebab kematian ibu berkisar antara 1,5% - 2,5 %.. Tujuan penelitian ini adalah untuk mengetahui hubungan antara status gravida dan riwayat penyakit genetik pada ibu hamil dengan kejadian preeklampsia berat di Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang Tahun 2012. Metode yang digunakan dalam penelitian ini adalah Survei Analitik dengan pendekatan Cross Sectional. Populasi dalam penelitian ini adalah kasus ibu hamil dengan preeklampsia berat dan kontrol yaitu ibu hamil dengan preeklampsia ringan. Jumlah sampel yang diperoleh sebanyak 242 ibu hamil, terdapat 181 ibu yang menderita Preeklampsia berat dan 61 ibu menderita preeklampsia ringan. Analisa data dilakukan secara univariat dan bivariat dengan uji statistik Chi-Square melalui tingkat kemaknaan α = 0,05. Untuk hasil analisa univariat dari 242 ibu hamil, 181 ibu ( 74,8 % ) menderita preeklampsia berat. Yang termasuk kategori ibu dengan primigravida sebanyak 131 orang ( 72,3 % ) dan ibu yang mempunyai riwayat penyakit genetik sebanyak 90 orang ( 49,7 % ). Sedangkan hasil dari analisa bivariat, uji statistik Chi-Square menunjukan bahwa ada hubungan yang bermakna antara status gravida dan kejadian preeklampsia berat dimana ( p value = 0,008 ) dan ada hubungan yang bermakna antara riwayat penyakit genetik dengan kejadian preeklampsia berat dimana ( p value = 0,012 ). Hasil penelitian ini diharapkan dapat menurunkan angka kejadian preeklampsia berat tentunya dengan melakukan pencegahan dan deteksi dini melalui pemeriksaan secara  teratur.  

scholarly journals The Influence of Gestational Age and Birth Weight on Neonatal Mortality

2020 ◽  
Vol 8 (3) ◽  
Author(s):  
Wedi Iskandar ◽  
Yeni Andayani ◽  
Lia Marlia ◽  
Burhan Burhan ◽  
Aris Primadi
Keyword(s):  
Logistic Regression ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Neonatal Mortality ◽  
Gestational Age ◽  
Multiple Logistic Regression ◽  
Chi Square ◽  
Percentage Contribution ◽  
Chi Square Test ◽  
Significant Health

Prematurity and low birth weight are some of the causes of neonatal death and significant health problem. This study aimed to determine the influence of gestational age and birth weight on neonatal mortality at the Al Islam Hospital Bandung in 2015–2019. It was a case-control retrospective observational analysis using medical records of the Al Islam Bandung Hospital from January 1, 2015, to December 31, 2019. The inclusion criteria for infants were born alive. Exclusion criteria had severe congenital abnormalities and gestational age <26 weeks. The chi-square test evaluated the univariate comparison test of risk factors between 2 groups. Multiple logistic regression to assess neonatal mortality's predictive factors and the percentage contribution of the influence was calculated (Nagelkerke’s R2 analysis). The number of infants enrolled in 2015–2019 was 6,791 neonates, and who died was 56 neonates (0.82%). In premature infants and low birth weight there was a very significant relationship with neonatal mortality, respectively p=0.000 (p<0.05) OR=30.397 (CI=16.506–55.976), and p=0.000 (p<0.05) OR=41.206 (CI=18.611–91.233). In the multiple logistic regression test, p=0.000 (p<0.05), with a Nagelkerke’s R2 value of 0.344 or 34.4%. This presence that gestational age and birth weight significantly affects neonatal mortality, either partially or simultaneously. The percentage contribution of the influence of gestational age and birth weight to neonatal mortality was 34.4%. PENGARUH USIA GESTASI DAN BERAT BADAN LAHIR TERHADAP KEMATIAN NEONATUSPrematuritas dan berat badan lahir rendah merupakan beberapa penyebab kematian neonatus dan masalah kesehatan yang signifikan. Penelitian ini bertujuan mengetahui pengaruh usia gestasi dan berat badan lahir terhadap kematian neonatus di RS Al Islam Bandung tahun 2015–2019. Penelitian ini merupakan penelitian observasional retrospektif kasus kontrol menggunakan data rekam medis RS Al Islam Bandung periode 1 Januari 2015 hingga 31 Desember 2019. Kriteria inklusi bayi lahir hidup. Kriteria eksklusi bayi dengan kelainan kongenital berat dan usia gestasi <26 minggu. Uji chi-square mengevaluasi perbandingan univariat faktor risiko antara 2 grup. Regresi logistik multipel untuk mengevaluasi faktor prediktif kematian neonatus dan persentase kontribusi pengaruh dihitung (Analisis R2 Nagelkerke). Jumlah bayi yang dirawat tahun 2015–2019 sebanyak 6.791 dan yang meninggal sebanyak 56 (0,82%). Pada bayi lahir prematur dan berat badan lahir rendah terdapat hubungan sangat bermakna terhadap kematian neonatus, berturut-turut p=0,000 (p<0,05) OR=30,397 (CI=16,506–55,976) dan p=0,000 (p<0,05) OR=41,206 (CI=18,611–91,233). Pada uji regresi logistik multipel, p=0,000 (p<0,05) dengan nilai R2 Nagelkerke sebesar 0,344 atau 34,4%. Usia gestasi dan berat badan lahir berpengaruh bermakna terhadap kematian neonatus, baik secara parsial maupun simultan. Persentase sumbangan pengaruh usia gestasi dan berat badan lahir terhadap kematian neonatus sebesar 34,4%.

scholarly journals FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEPATUHAN MASYARAKAT TERHADAP PROTOKOL KESEHATAN COVID-19

2021 ◽  
Vol 3 (2) ◽  
pp. 207-212
Author(s):  
Felix Kasim ◽  
Beni Satria ◽  
Balqis Wasliati ◽  
Kuat Sitepu ◽  
Ika Nur Saputri ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Secondary Data ◽  
Total Sample ◽  
Physical Distance ◽  
Multiple Logistic Regression ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Cross Sectional Design ◽  
Regression Tests

The COVID-19 pandemic outbreak is increasingly deadly and is expanding beyond China. Batu Bara Regency is one of the districts that has experienced an increase in confirmed cases of COVID-19. The success of the COVID-19 health protocol practice is largely determined by the compliance of the community in carrying out the 3M movement, namely using masks, washing hands with soap, and maintaining physical distance. The purpose of this study was to determine the factors related to community compliance with the COVID-19 health protocol in Datuk Lima Puluh District, Batu Bara Regency. This study was an observational analytic study with a cross sectional design. The population in this study were all people in Datuk Lima Puluh District, Batu Bara Regency and the total sample was 393 people. Data collection was carried out with primary and secondary data. Data analysis was performed using the chi-square test and multiple logistic regression. The results of the chi-square test show that there is a relationship between knowledge and availability of facilities and community compliance with the COVID-19 health protocol in Datuk Lima Puluh District, Batu Bara Regency. The results of multiple logistic regression tests show that respondents who do not have the availability of facilities have 1,904 times the chance of not adhering to the COVID-19 health protocol. Suggestions for the health office and health services are expected to increase health socialization related to the prevention of COVID-19 so that people can comply with health protocols.

scholarly journals Determinants of Stunting Events in Children Aged 6-23 Months in Locus and Non-Locus Areas in East Luwu Regency

2020 ◽  
Vol 1 (6) ◽  
pp. 7-16
Author(s):  
Kanaang Mabe Parenreng ◽  
Veni Hadju ◽  
Burhanuddin Bahar ◽  
Nurhaedar Jafar ◽  
Healthy Hidayanty ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Exclusive Breastfeeding ◽  
Parental Education ◽  
Family Members ◽  
Hand Washing ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
History Of ◽  
Diarrhea Disease

Nationally, the prevalence of stunting in children under five in Indonesia is 30.8%. The incidence of stunting varies from region to region. This study aims to determine the determinants of stunting in children aged 6-23 months in the locus and non-loci in East Luwu Regency. This research is an observational analytic study using a cross sectional design. The study population was 858 children aged 6-23 months in five locus villages and five non-locus villages. A sample of 200 people was taken using purposive sampling method, data were analyzed using the chi square test and logistic regression using the SPSS application. The results showed the similarity in terms of parental education in both regions. In general, the father has a job and the mother is a housekeeper. Income levels are higher in locus areas. As much as 43.1% of baduta had stunting at locus area and 22.4% at non locus. The logistic regression test showed that the factors associated with stunting in the locus were family members smoking (p = 0.032), hand washing practices (p = 0.036) and exclusive breastfeeding (p = 0.001). Meanwhile, non-locus areas were a history of diarrhea disease (p = 0.049) and hand washing practices (p = 0.052). Combined analysis of locus and non-loci showed that family members smoking (p = 0.005), exclusive breastfeeding (p = 0.001), frequency of complementary feeding (p = 0.027) and hand washing practices (p = 0.001) were determinants of stunting. The most dominant variable in the locus was exclusive breastfeeding, while non-locus was a history of diarrhea. Conclusion: The determinants of locus stunting are family members smoking, hand washing practices and exclusive breastfeeding. Meanwhile, non-locus areas are a history of diarrhea disease and hand washing practices.

scholarly journals Lumbar spondylolisthesis is a risk factor for osteoporotic vertebral fractures: a case–control study

2018 ◽  
Vol 46 (9) ◽  
pp. 3605-3612
Author(s):  
Peng Wang ◽  
Feng Wang ◽  
Yan-Long Gao ◽  
Jia-qi Li ◽  
Jing-tao Zhang ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Previous History ◽  
Vertebral Compression Fractures ◽  
Chi Square ◽  
Compression Fractures ◽  
Chi Square Test ◽  
History Of ◽  
Lumbar Spondylolisthesis

Objective This study aimed to identify the risk factors for vertebral compression fractures in patients with osteoporosis. Methods A total of 864 patients with osteoporosis were enrolled in a retrospective study from February 2010 to June 2016. Patients with diseases, such as pathological fractures, high-energy direct injury to the thoracic or lumbar vertebrae, and severe spinal deformity, were excluded. The patients were divided into two groups: those with vertebral compression fractures (288) and those with no vertebral compression fractures (576). Information on the patients’ age, sex, lumbar bone mineral density (BMD), trauma, body mass index, previous history of vertebral compression fractures, and spondylolisthesis was recorded. Logistic regression analysis and the chi-square test were applied for comparisons. Results Univariate logistic regression analysis and chi-square test results showed no significant differences in age, sex, body mass index, type 2 diabetes, previous history of vertebral fracture, and trivial trauma between the groups. Multivariate analysis showed significant associations between spondylolisthesis and BMD. Logistic regression analysis showed that spondylolisthesis and BMD were risk factors for vertebral compression fractures. Conclusions Lumbar spondylolisthesis is an independent risk factor for vertebral compression fractures in patients with osteoporosis. Therefore, patients with osteoporosis and lumbar spondylolisthesis require more attention.

scholarly journals Analisis Faktor-Faktor yang Memengaruhi Kualitas Hidup Penderita Talasemia Anak di RSUD Al-Ihsan Kabupaten Bandung Tahun 2019

2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Jamaluddin Kamil ◽  
Tito Gunantara ◽  
Yani Dewi Suryani
Keyword(s):  
Quality Of Life ◽  
Logistic Regression ◽  
Social Function ◽  
Dominant Factor ◽  
Multiple Logistic Regression ◽  
Chi Square ◽  
Regression Test ◽  
Chi Square Test ◽  
Logistic Regression Test

Talasemia merupakan penyakit genetik dan kronis yang dapat menyebabkan anemia berat sehingga mengganggu kualitas hidup. Penelitian ini bertujuan untuk mengetahui gambaran dan faktor apa saja yang memengaruhi kualitas hidup penderita talasemia anak di RSUD Al- Ihsan Kabupaten Bandung tahun 2019. Subjek penelitian adalah pasien talasemia anak di RSUD Al-Ihsan Kabupaten Bandung yang memenuhi kriteria inklusi. Data diambil menggunakan teknik total sampling dengan jumlah subjek 65 orang. Desain penelitian bersifat analitik dengan rancangan potong lintang. Penelitian menggunakan alat berupa kuesioner pediatric quality of life (PedsQL) yang berisi 23 pertanyaan. Hasil analisis univariat didapatkan kualitas hidup total subjek penelitian adalah buruk dengan rerata skor 68,9. Fungsi fisik, emosi, dan sekolah buruk dengan nilai rerata skor <80. Analisis bivariat dengan chi square test didapatkan hubungan bermakna antara faktor-faktor dengan kualitas hidup dengan nilai p≤0,05. Analisis multivariat dengan multiple logistic regression test didapatkan faktor yang paling dominan memengaruhi kualitas hidup yaitu fungsi sosial dengan koefisien beta 1,823 dan nilai p=0,039. Simpulan, rerata kualitas hidup penderita talasemia anak di RSUD Al-Ihsan Kabupaten Bandung adalah buruk. Fungsi yang terganggu yaitu fungsi fisik, emosi, dan sekolah. Faktor yang paling dominan memengaruhi kualitas hidup dengan nilai tertinggi yaitu fungsi sosial. ANALYSIS OF FACTORS THAT INFLUENCE THE QUALITY OF LIFE OF CHILDREN WITH THALASSEMIA IN RSUD AL-IHSAN BANDUNG IN 2019Thalassemia is a genetic and chronic disease that can cause severe anemia that disrupts the quality of life. The purpose of this study was to determine the description and factors that influence the quality of life of children with thalassemia in RSUD Al-Ihsan Bandung in 2019. The subjects were pediatric thalassemia patients in RSUD Al-Ihsan Bandung who met the inclusion criteria. Data were taken using a total sampling technique with a total 65 subjects. This study design was analytic with cross sectional design. This study used a tool of a Pediatric Quality of Life (PedsQL) questionnaire containing 23 questions. Univariate analysis results found that the total quality of life of the study subjects was poor with a mean score of 68.9. Physical, emotional, and school functions were poor with an average score of <80. Bivariate analysis with chi square test found a significant relationship between factors with quality of life with a p value ≤0.05. Multivariate analysis with multiple logistic regression test found that the most dominant factor affecting the quality of life was social function with a beta coefficient of 1.823 (p=0.039). Conclusions, the average quality of life of children with thalassemia in RSUD Al-Ihsan in Bandung is poor. Functions that are disrupted are physical, emotional, and school functions. The most dominant factor influencing the quality of life with the highest value is social function.

Multivariate analysis of determinant factors in adjuvant chemotherapy (AC) utilization in patients with stage II colon cancer (CC): Analysis of the National Cancer Database (NCDB).

2017 ◽  
Vol 35 (4_suppl) ◽  
pp. 577-577
Author(s):  
Donny V. Huynh ◽  
Shiva Kumar Reddy Mukkamalla ◽  
Ponnandai Sadasivan Somasundar ◽  
Ritesh Rathore
Keyword(s):  
Logistic Regression ◽  
Multivariate Analysis ◽  
Single Agent ◽  
Stage Ii ◽  
Distribution Analysis ◽  
Multiple Logistic Regression ◽  
Chi Square ◽  
Primary Tumors ◽  
Chi Square Test ◽  
Multi Agent

577 Background: Evidence from randomized controlled trials does not support routine use of AC for patients with stage II CC. Clinical guidelines recommend discussion of AC in patients with high-risk disease. In our study, we analyzed NCDB data to determine factors favoring the use of AC in this setting. Methods: NCDB data was extracted on a total of 45,098 patients from 2004 to 2009 with stage II CC. Descriptive characteristics were analyzed using Chi-square test and odds ratios were calculated using multiple logistic regression. Results: Frequency of AC was significantly different among patients belonging to different age groups, tumor laterality, grade, pathologic tumor status (pT), and clinical nodal status (cN) (Chi-square test; p < 0.0001). Age distribution analysis revealed higher frequency of AC administration among patients of 18-64 years compared to those of 65-74 years and older, irrespective of single-agent or multi-agent regimens (p < 0.0001). Multivariate analysis was performed using multiple logistic regression technique. The odds of AC administration increased with increasing pT status, worsening tumor grade, and inadequate lymph node dissection ( < 12 lymph nodes evaluated) (p < 0.0001). AC administration was also more likely with left sided primary tumors (p < 0.0001). Conclusions: Using NCDB data, our analysis reveals conventional factors which are associated with AC administration in patients with resected stage II CC. Use of single-agent vs. multi-agent regimens did not differ, though elderly patients and those without left sided tumors were less likely to receive AC. Oncologists should be able to utilize these findings in discussions with stage II CC patients regarding the use of AC. [Table: see text]

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