scholarly journals Compromised liver function in patients with a new coronavirus infection COVID-19

2021 ◽  
Vol 99 (1) ◽  
pp. 63-67
Author(s):  
L. Yu. Eliseeva ◽  
A. S. Eliseev ◽  
N. Yu. Borovkova ◽  
A. S. Vasilkova
Keyword(s):  
Biological Therapy ◽  
Wilcoxon Test ◽  
Entire Period ◽  
P Value ◽  
Biologic Drugs ◽  
Haemophagocytic Syndrome ◽  
Significant Difference ◽  
Hepatic Transaminase ◽  
Coronavirus Infection ◽  
Anti Inflammatory

Clinicians have noted an increase in the level of hepatic transaminase in patients with the new coronavirus infection COVID-19 a number of times, and an unambiguous answer to the question of what caused this change in laboratory indices has not been received yet. The course of COVID-19 is often complicated by the development of haemophagocytic syndrome, and preventive anti-inflammatory therapy is required for its treatment, which is represented by biologic drugs (interleukin-6 inhibitors or JAK-kinase blockers) and glucocorticosteroids. It has been noted that the level of ALT and AST increases against the background of biological therapy.The objective of the present study was to analyze the possible effect of biological therapy on the functional state of the liver.Material and methods. The study randomly included 38 patients diagnosed with ICD-10 U07.1 (18 women and 20 men). Inclusion criteria were control of aspartate aminotransferase (AST), alanine aminotransferase (ALT), bilirubin at least three times during the period of hospitalization, as well as an increase in these indicators above the reference values. This study was carried out while prescribing preventive anti-inflammatory therapy.Results. The median (Me ± SD) age of the patients was 57 ± 14.67. Mann–Whitney U-test showed no significant difference in the activity of liver enzymes and total bilirubin upon admission to the infectious diseases hospital (p> 0.05). A statistically significant difference in indicators evaluation at admission and at discharge was determined using the Wilcoxon test for ALT levels in the group receiving biologic drugs (p = 0.004). In other cases, there was no statistically significant difference (p > 0.05). When analyzing the level of enzymes for the entire period of hospitalization with the use of Friedman criterion, the level of changes in hepatic transaminases in the group with the use of biologic drugs turned out to be equal for ALT p = 0.001. When assessing changes over the entire period of hospitalization by the de Ritis coefficient, the p-value was also significant (0.001) in this group.Conclusion. This study shows the necessity to control the level of hepatic transaminase, especially when prescribing biological therapy for haemophagocytic syndrome.

scholarly journals PENURUNAN NYERI KEPALA PADA LANSIA DENGAN HIPERTENSI MENGGUNAKAN RELAKSASI AUTOGENIK DI KELURAHAN MERSI PURWOKERTO

2019 ◽  
Vol 7 (2) ◽  
pp. 104-113
Author(s):  
Dwi Novitasari ◽  
Ikit Netra Wirakhmi
Keyword(s):  
The Elderly ◽  
Wilcoxon Test ◽  
Relaxation Technique ◽  
P Value ◽  
Common Symptom ◽  
Parasympathetic System ◽  
Significant Difference ◽  
Before And After ◽  
Autogenic Relaxation ◽  
The Mean

Background: Headache in the occipital region is the most common symptom of hypertension, caused by enhanchement intra-cranial pressure and vasoconstriction resulting in decreased perfusion of cerebral tissue. This causes insomnia, decreased concentration and decreased ability of daily living activity. Autogenic relaxation causes vasodilation and a calm emotional response that increases the response of the parasympathetic system. This modulation stimulus can decrease perception of headache. Objective: The aims of this study was to find out how the reduction of headache on hypertension before and after autogenic relaxation. Methods: The design of this research was pre experimental with one group pretest-postest design approach. The sample are 38 patients with hypertension who complained of headache in Mersi Purwokerto. Selection has been using purposive sampling. Measurement of head pain using visual analog scale. Data analysis using Wilcoxon test. Results: The mean headache before the autogenic relaxation technique was 5.24, and the mean headache after autogenic relaxation technique was 3.47, including the range of moderate pain. There was a significant difference between headache before and after the autogenic relaxation technique with p value: 0,000. Conclusion: Autogenic relaxation can be used by the elderly with hypertension to reduce headache. Keywords: Autogenic relaxation, headache, hypertension.

scholarly journals CD4 LYMPHOCYTE IN HIV / AIDS BEFORE AND AFTER ANTIRETROVIRAL THERAPY

2017 ◽  
Vol 13 (2) ◽  
pp. 183
Author(s):  
Rangsang Bagus Prabowo ◽  
Dewi Indah Noviana Pertiwi ◽  
FX. Hendriyono
Keyword(s):  
Antiretroviral Therapy ◽  
Lymphocyte Count ◽  
Wilcoxon Test ◽  
P Value ◽  
Cross Sectional ◽  
Infected People ◽  
Significant Difference ◽  
Cd4 Lymphocyte Count ◽  
Before And After ◽  
Cd4 Lymphocyte

Abstract: Human Immunodefficiency Virus (HIV) is a virus that decreases the human immunity system, therefore the infected people become susceptible to any kind of infections. Examination of CD4 lymphocyte count periodically is one of the antiretroviral therapy success indicators. The purpose of this research was to determine the difference of CD4 lymphocyte count before and after antiretroviral therapy at Ulin General Hospital Banjarmasin on 2013-2015. The method of this research was observational analytic with cross-sectional approach. The study population was 55 patients which were selected by inclusion and exclusion criteria. Results portrayed an increase of the CD4 lymphocyte count in 51 patients after being given four kinds of antiretroviral for 6 months with the mean increase in CD4 lymphocyte count was 92,72 cell/µL. Data analysis result with Wilcoxon test portrayed a difference of the CD4 lymphocyte count before and after antiretroviral therapy with p value=0,000. In conclusion, there was a significant difference of the CD4 lymphocyte count before and after antiretroviral therapy. Keywords: Human Immunodeficiency Virus, CD4, lymphocyt, antiretroviral therapy

scholarly journals Perbedaan pH Saliva Sebelum Dan Sesudah Mengunyah Permen Karet Xylitol Pada Pemakai Alat Orthodonti Cekat

2018 ◽  
Vol 6 (1) ◽  
pp. 15-19
Author(s):  
Gita Komala Dewi ◽  
Susilarti Susilarti ◽  
Almujadi Almujadi
Keyword(s):  
Environmental Changes ◽  
Salivary Flow ◽  
Oral Bacteria ◽  
Wilcoxon Test ◽  
P Value ◽  
Orthodontic Appliance ◽  
Significant Difference ◽  
Salivary Ph ◽  
Before And After ◽  
Fixed Orthodontic Appliance

Orthodontic treatment may lead to environmental changes in the oral cavity that may occur in a number of users of the orthodontic appliance, such as changes in bacterial concentration, salivary buffering capacity, salivary acidity (pH) and salivary flow rate. Xylitol stimulates salivary flow and helps restore saliva acid/base balance because it cannot be converted to acid by oral bacteria. To identify the difference in salivary pH before and after chewing xylitol gum in the users of fixed orthodontic appliance. This research is quasi-experimental with one group pretest-posttest design. Samples were students of SMA Kolombo Sleman who used a fixed orthodontic appliance. Data were analyzed using a Wilcoxon test. The salivary pH of the users of a fixed orthodontic appliance before chewing xylitol gum mostly belonged to acid criterion (43.8%), and the base criterion (34.3%). After chewing xylitol gum, the salivary pH of the users of fixed orthodontic appliance mostly belonged to a neutral criterion (78.1%). The results of the Wilcoxon test showed that the salivary pH before and after chewing gum xylitol in the users of fixed orthodontic appliance had a P value of 0.027 <α 0.05. There is a significant difference in salivary pH before and after chewing xylitol gum in users of fixed orthodontic appliance.

scholarly journals Manfaat Relaksasi Otot Progresif Bagi Klien DM Tipe II Untuk Mengurangi Gejala Fatigue

2021 ◽  
Vol 6 (2) ◽  
pp. 45-52
Author(s):  
Reny Sulistyowati
Keyword(s):  
Muscle Relaxation ◽  
Intervention Group ◽  
Progressive Muscle Relaxation ◽  
Wilcoxon Test ◽  
Bivariate Analysis ◽  
Control Group ◽  
P Value ◽  
Diabetic Patients ◽  
Significant Difference ◽  
Before And After

Fatigue is a widespread clinical complaint among adults with type 2 diabetes. Fluctuating glucose levels can cause fatigue. Several factors are associated with fatigue in diabetic patients, including physiological factors such as hypoglycemia or hyperglycemia, psychological factors such as depression associated with diabetes. Progressive muscle relaxation is a procedure to get relaxation in the muscles through two steps, namely by applying tension to a muscle group and stopping the tension then focusing on how the muscle relaxes, feeling the sensation of relaxation and fatigue is reduced. The aim of this study was to identify the effect of progressive muscle relaxation on fatigue symptoms in type II DM clients in 15 control groups and 15 intervention groups. The research method used a quasi-experimental design with a pretest-posttest control group design approach, consisting of one treatment (in the intervention group) and a control group. Data analysis was performed using univariate and bivariate analysis using t-independent and t-dependent tests. Wilcoxon test results in the intervention group and the control group showed a significant p-value of 0.002 (<0.05), meaning that there was a significant difference in fatigue symptoms in the intervention group before and after the intervention. This shows that there was a decrease in fatigue symptoms in the intervention group before and after combination OHO therapy and progressive muscle relaxation exercises (previously the average respondent in the intervention group experienced symptoms of severe fatigue, after intervention, the average value of fatigue symptoms turned into mild fatigue ). Conclusion: Progressive muscle relaxation combined with OHO therapy can reduce symptoms of fatigue compared to only OHO therapy.

scholarly journals Primary Dysmenorrhea Intensity Between Stretching Abdominal Therapy and Acupuncture to Adolescent Girls

2021 ◽  
Vol 4 (3) ◽  
Author(s):  
Ni Nyoman Suindri ◽  
◽  
Ni Luh Putu Sri Erawati ◽  
Made Widhi Gunapria Darmapatni ◽  
Ni Gusti Kompiang Sriasih
Keyword(s):  
High School ◽  
High School Students ◽  
Adolescent Girls ◽  
Rating Scales ◽  
Wilcoxon Test ◽  
P Value ◽  
Menstrual Pain ◽  
Significant Difference ◽  
Before And After ◽  
The Difference

Menstrual pain or dysmenorrhea is known as cramping pain in the lower abdomen during menstruation experienced by some women. Abdominal stretching exercises and acupressure can reduce dysmenorrhea. This research aims to determine the difference in the intensity of primary menstrual pain (dysmenorrhea) between abdominal stretching therapy and acupressure for adolescent girls in a Senior High School in Denpasar. The method applied in this research is a Quasi-Experimental two-groups pretest-posttest design. The research sample was grouped into two, namely 70 high school students in the abdominal stretching therapy and 70 students in acupressure therapy. The data were collected using the Numerical Rating Scales or NRS. The data were then analysed using the Wilcoxon test and Mann Whitney test. The result of the research showed that there was a significant difference in dysmenorrhea before and after abdominal stretching therapy (p=0.000). Also, there was a significant difference in dysmenorrhea before and after acupressure therapy (p=0.000). There was no difference in dysmenorrhea before applying abdominal stretching therapy and acupressure with a p-value=0.335. Also, there was no difference in dysmenorrhea after both therapies were undergone in two groups (p=0,111). The difference test on the difference between the pre-test and post-test obtained p-value = 0.012. Hence, there was a significant difference in decreasing dysmenorrhea between abdominal stretching therapy and acupressure (p=0.012). Conclusion: there is a significant difference in reducing dysmenorrhea between abdominal stretching therapy and acupressure. Suggestion: further research is necessary to conduct by using time series design.

scholarly journals EFEKTIVITAS LATIHAN PERNAFASAN RELAKSASI TERHADAP KELELAHAN PADA PASIEN KANKER YANG MENJALANI KEMOTERAPI

2020 ◽  
Vol 8 (01) ◽  
pp. 144-158
Author(s):  
Vervando Janter Sumilat ◽  
Prabawati Prabawati ◽  
Sudibyo Supardi
Keyword(s):  
Cancer Patients ◽  
Intervention Group ◽  
Sampling Technique ◽  
Wilcoxon Test ◽  
Control Group ◽  
P Value ◽  
Breathing Exercise ◽  
Chemotherapy Drugs ◽  
Breathing Exercises ◽  
Significant Difference

Abstract Background: Cancer patients with chemotherapy experience fatigue as cancer effects and cell destruction due to the toxicity of chemotherapy drugs. Objective: Determine the effectiveness of relaxation breathing exercises to fatigue cancer patients who undergoing chemotherapy. Methode: This research used quasi experiment pretest and posttest method. There were 92 respondents who examined using purposive sampling technique and divided into 46 respondents as intervention group and 46 respondents as control group. Relaxation breathing exercise was given four weeks for intervention group on April-July 2018 in Siloam Hospital Manado. Result: The majority of cancer patients were age 45-65 years 69,9%, 54,3% were diagnosed cancer ≤1 year and 79,3% received combination chemotherapy. The result of Wilcoxon test revealed there was significant difference before and after intervention to fatigue (p value = 0,00), with mean rank of reduction 21,97% on fatigue. The result of Mann Whitney test revealed that there was significant difference in fatigue between intervention and control groups (p value = 0,00). Multivariate logistic regression revealed that there was an effect of relaxation breathing exercise on fatigue (p value = 0,00) and relaxation breathing exercise may reduce 60,46 times of fatigue on patients who undergoing chemotherapy. Conclusion: Relaxation Breathing Exercise can reduce fatigue in cancer patients who undergoing chemotherapy in Siloam Hospital Manado. It is recommended to perform relaxation breathing exercise as a routine exercise for cancer patients during chemotherapy to minimize fatigue. Keywords: Relaxation Breathing Exercise, Fatigue, Chemotherapy, Cancer

scholarly journals The Effect of Blended Learning on Nursing Students’ Knowledge

Jurnal NERS ◽  
2019 ◽  
Vol 14 (3) ◽  
pp. 1
Author(s):  
Ni Gusti Ayu Eka ◽  
Grace Solely Houghty ◽  
Juniarta Juniarta
Keyword(s):  
Nursing Students ◽  
Blended Learning ◽  
Industrial Revolution ◽  
Nursing School ◽  
Wilcoxon Test ◽  
P Value ◽  
Final Exam ◽  
Significant Difference ◽  
Statistics Course ◽  
The Mean

Introduction: Blended learning is assumed to improve the students’ understanding of learning at nursing school especially in the current industrial revolution 4.0 era.  The combination of classroom and online activities is expected to provide better study outcomes.  This research aimed to compare the knowledge scores of the nursing students in blended learning concerning a research and statistics course at a private faculty of nursing.Methods: The knowledge scores resulted from the student’s score in their mid and final examinations (0-100). A total of 474 respondents who were third year students involved in the study.  This study applied a pre-experimental design. Due to the data having a significant non-normal value (p value < 0.001), this study further compared the mean-rank of the students’ score using a Wilcoxon test analysis.Results: The results of this study revealed that there was a significant difference (p value < 0.0001) between the students’ score in the mid (Median 72.5; SD 9.82) and final exam examinations (Median 86.66; SD 4.75). This means that the students had a better score in their final exam.Conclusion: Applying a blended learning method was a positive experience for the nursing students in terms of knowledge. It is needed to explore the students’ understanding and interest in their learning process using blended learning.

scholarly journals Comparison of Lecture and Video Methods in Increasing Caregiver Knowledge in Treating Clients Halusination

2018 ◽  
Vol 6 (2) ◽  
Author(s):  
Bambang Eryanto ◽  
Taty Hernawaty ◽  
Shelly Iskandar
Keyword(s):  
Sampling Technique ◽  
Knowledge Score ◽  
Wilcoxon Test ◽  
Control Group ◽  
P Value ◽  
Lecture Method ◽  
Significant Difference ◽  
Research Findings ◽  
Video Group ◽  
And Control

Efforts to improve caregiver’s knowledge on hallucination is by providing an education the caregivers. Enhancing such knowledge can be carried out by different methods, include lecture and watching video methods. The purpose of the present research was to compare the effectiveness of lecture  and watching video method in enhancing caregiver’s knowledge on hallucination.          The research used a quasi-experiment method with a pretest and posttest group design, with the research sample was 60. The sampling technique used was a total sampling. The scores of caregiver’s knowledge were determined by a questionnaire of knowledge on hallucination that was self-developed by validity test (0.707) and reliability test (0.968). The data obtained was then tested by using Independent Sample T-test, Mann-Whitney test, and Wilcoxon test.          The result of pretest of caregiver’s knowledge before the intervention showed that there was no difference between intervention and control group (p-value=0.624), while result of posttest of caregiver’s knowledge after the intervention showed that there was a significant difference between lecture group and video group (p-value=0.000). The research findings revealed that there was a significant increase in the scores of knowledge for both methods (p-value=0.000), but the increase of video group’s knowledge score was higher (4.23) than that of lecture group (2.57).          The conclusion of the research was that wathing video method was more effective than lecture method in enhancing caregiver’s knowledge so that video can be used as an alternative method for mental health education.

scholarly journals EDUKASI MASYARAKAT PEDULI AIR BERSIH DALAM UPAYA PENINGKATAN PENGETAHUAN MASYARAKAT TENTANG CARA PENGELOLAAN AIR MINUM DI DESA PEMURUS RT 3B KECAMATAN ALUH-ALUH BERBASIS DARING

2021 ◽  
Vol 5 (1) ◽  
pp. 560
Author(s):  
Nadia Hildawati ◽  
Meliyana Meliyana ◽  
Rizka Elma Selviana ◽  
Asrina Magfiroh ◽  
Atikah Rahayu ◽  
...  
Keyword(s):  
Drinking Water ◽  
Rural Areas ◽  
Wilcoxon Test ◽  
P Value ◽  
Clean Water ◽  
Knowledge And Attitudes ◽  
The People ◽  
Significant Difference ◽  
Before And After ◽  
Post Test

ABSTRAKAir merupakan kebutuhan bagi setiap kehidupan, semua makhluk hidup memerlukan air dalam kehidupannnya sehingga tanpa air dapat dipastikan tidak akan ada kehidupan. Sebagian besar masyarakat yang mengalami kesulitan memperoleh air bersih untuk digunakan sebagai air minum tersebut adalah masyarakat yang tinggal di perdesaan. Kegiatan ini bertujuan untuk meningkatkan pengetahuan dan sikap masyarakat tentang cara pengelolaan air minum di Desa Pemurus RT.3B Kecamatan Aluh-Aluh. Sasaran kegiatan ini adalah masyarakat Desa Pemurus RT.3B Kecamatan Aluh-Aluh yang berjumlah 15 orang. Kegiatan ini sebagai salah satu bentuk untuk meningkatkan pengetahuan dan sikap masyarakat tentang cara pengelolaan air minum. Metode pelaksanaan kegiatan intervensi berupa penyuluhan yang dilakukan melalui media whatsApp group. Hasil pre dan post test dilakukan analisis statistik menggunakan uji wilcoxon untuk mengetahui apakah terdapat perbedaan sebelum dan sesudah dilakukan intervensi. Hasil penyuluhan ini menunjukkan bahwa terdapat perbedaan hasil pre test dan post test pengetahuan sebelum dan sesudah dilakukan penyuluhan (p-value=0,038). Namun pada sikap didapatkan hasil tidak ada perbedaan yang signifikan antara sikap masyarakat sebelum dan sesudah dilakukan penyuluhan (p-value=1,000). Diharapkan masyarakat bisa mengelola air minum agar nantinya dapat menciptakan derajat kesehatan yang lebih baik. Kata kunci: air bersih; pengelolaan air minum; penyuluhan ABSTRACTWater is a necessity for every life, all living things need water in their life so that without water it is certain that there will be no life. Most of the people who have difficulty obtaining clean water to use as drinking water are people who live in rural areas. This activity aims to increase public knowledge and attitudes about how to manage drinking water in Pemurus Village RT.3B, Aluh-Aluh District. The target of this activity is the Pemurus Village community, RT.3B, Aluh-Aluh District, totaling 15 people. This activity is a form of increasing community knowledge and attitudes about how to manage drinking water. The method of implementing intervention activities is in the form of counseling carried out through whatsapp group media. The results of the pre and post tests were statistically analyzed using the Wilcoxon test to determine whether there were differences before and after the intervention. The results of this counseling showed that there were differences in the results of the pre-test and post-test of knowledge before and after the counseling (p-value 0.038). However, in attitudes, the results showed that there was no significant difference between the attitudes of the community before and after the counseling (p-value 1,000). It is hoped that the community can manage drinking water so that later it can create a better health degree. Keywords: clean water; drinking water management; counseling

Evaluation of the influence of education on the ergonomic risk of concrete form workers

Work ◽  
2020 ◽  
Vol 67 (4) ◽  
pp. 1007-1013
Author(s):  
Abdollah Gholami ◽  
Jalaluddin Tamaddon Yalameh ◽  
Behzad Fouladi-Dehaghi ◽  
Davood Eskandari ◽  
Gholamheidar Teimori-Boghsani
Keyword(s):  
Musculoskeletal Disorders ◽  
Wilcoxon Test ◽  
P Value ◽  
Practical Training ◽  
Entire Body ◽  
Time Data ◽  
Post Intervention ◽  
Concrete Form ◽  
Significant Difference ◽  
Ergonomic Risk

BACKGROUND: In developing countries, construction is a largely manual job that imposes awkward postures on workers, thus facilitating a variety of musculoskeletal disorders. Ergonomic training is known as an effective way to reduce these disorders. OBJECTIVE: This study aimed to evaluate the effectiveness of ergonomic training intervention in reducing the ergonomic risk of concrete form workers. METHODS: This quasi-experimental study was carried out on 144 concrete form workers employed in the construction projects of Gonbad-e Kāvus, Iran, Iran. Data was collected using the Nordic Musculoskeletal Questionnaire (at the pre-intervention stage) and the Rapid Entire Body Assessment (REBA) worksheet (at the pre- and post-intervention stages). Ergonomic training was provided via face-to-face educational meetings along with presenting informative pamphlets, which took place over 45 days duration of time. Data were analyzed by the use of SPSS software version 21, t-test and Wilcoxon test. Significant level was considered at P-value less than 0.05. RESULTS: Musculoskeletal disorders were observed in all limbs of the studied workers. The most prevalent disorders were the pain in the shoulder region of lift operators (86.1%) and the pain in the back area of mixer operators (77.8%). About 99.3% of all concrete form workers were exposed to a moderate level of ergonomic risk and needed posture correction. Pre- and post-training REBA scores showed a statistically significant difference (P < 0.05). CONCLUSION: Although the ergonomic training did reduce the ergonomic risk of workers, because of its short duration, it failed to reduce this risk to an acceptable level. It is recommended to hold both theoretical and practical training sessions over longer periods of time.

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