scholarly journals European Approaches to Japanese Language and Linguistics

2020 ◽  
Author(s):  
Giuseppe Pappalardo ◽  
Patrick Heinrich
Keyword(s):  
Wide Spectrum ◽  
Japanese Language ◽  
Original Research ◽  
New Approaches ◽  
European Universities ◽  
Wide Range ◽  
Language Study ◽  
Japanese Studies ◽  
And Linguistics

In this volume European specialists of Japanese language present new and original research into Japanese over a wide spectrum of topics which include descriptive, sociolinguistic, pragmatic and didactic accounts. The articles share a focus on contemporary issues and adopt new approaches to the study of Japanese that often are specific to European traditions of language study. The articles address an audience that includes both Japanese Studies and Linguistics. They are representative of the wide range of topics that are currently studied in European universities, and they address scholars and students alike.

The use of telemedicine for delivering healthcare in Japan: Systematic review of literature published in Japanese and English languages

2017 ◽  
Vol 23 (10) ◽  
pp. 828-834 ◽  
Author(s):  
Jun Ito ◽  
Sisira Edirippulige ◽  
Takeshi Aono ◽  
Nigel R Armfield
Keyword(s):  
English Language ◽  
Healthcare Access ◽  
Japanese Language ◽  
Cochrane Library ◽  
Ageing Population ◽  
Clinical Use ◽  
Wide Range ◽  
Japanese Studies ◽  
Remote Monitoring Systems ◽  
Study Type

Background In common with other countries, Japan has an ageing population and geographical impediments to healthcare access. The role of telemedicine within the Japanese health system may be of wide interest, yet it has not been comprehensively explored and documented. Thus, the aim of this study was to systematically review the Japanese and English language literature relating to the clinical use of telemedicine in Japan. Methods For studies published in Japanese, we searched Ichushi and CiNii. For English language publications, we searched Cochrane Library, PubMed, Embase, and Web of Science. All peer-reviewed articles describing the clinical use of telemedicine and published between 2007 and 2016 were included. Data on clinical area, study type, technology used, and type of communication were extracted. Studies were categorised by prevention, screening, diagnosis, surveillance, and treatment. Results The search yielded 1476 records; 26 Japanese language and 15 English language articles were selected for review. A wide range of clinical areas were represented; however, home care and life-style related studies were dominant. More than 50% of studies were related to prevention and early diagnosis. The majority of Japanese studies involved doctor-to-doctor consultation. Smartphones and remote monitoring systems were the main types of technology used. Conclusions Most studies of telemedicine in Japan are published in the Japanese language and are thus relatively inaccessible to the rest of the world; for the first time, this study has provided an overview of the clinical use of telemedicine in Japan. The clinically related papers reflect the Japanese cultural focus on disease prevention.

Injustice and Revolt

2021 ◽  
pp. 186-233
Author(s):  
Mark Bailey
Keyword(s):  
Original Research ◽  
Black Death ◽  
Common Cause ◽  
Court Records ◽  
New Approaches ◽  
Wide Range ◽  
Royal Courts ◽  
Local Officials ◽  
Diverse Groups

If a seigniorial reaction did not materialize in the generation after the arrival of Black Death, and if villeinage really was dissolving rapidly during that period, how then do we explain the Peasants’ Revolt in 1381? The arguments and evidence for the centrality of serfdom to the revolt are discussed, and the latest research into the targets and participants considered. This chapter takes its lead from new approaches to medieval revolts, which move away from modern preoccupations with class and revolution to reconstruct how common grievances united disparate groups of people. It explores the experience of royal justice—principally the labour laws and the leasing of hundreds—from ‘below’, based upon a fresh dissection of the legislation and original research into petitions, the sessions of JPs and King’s Bench, and other court records. The nature of the legislation, the mechanics of its enforcement, the powers and discretion vested in local officials well below the level of the JPs, and the wide range of jurisdictions for handling and sanctioning the same offence resulted in wide inconsistencies in its enforcement. This created divisions within communities, not just along class lines between lord and peasant, and generated common cause and forged temporary alliances among diverse groups. The unifying aim of the rebels was the removal of all forms of lordship other than the king and the removal of all intermediary private and royal courts: opposition to serfdom was one element within this greater aim.

NEW APPROACHES TO THE ORGANIZATIONAL AND TECHNICAL SUPPORT OF THE EXAMINATION OF COMPETITIVE APPLICATIONS FOR STATE SUPPORT IN THE FORM OF GRANTS OF THE PRESIDENT OF THE RUSSIAN FEDERATION TO YOUNG RUSSIAN SCIENTISTS – DOCTORS OF SCIENCES AND PHILOSOPHY DOCTORS (DOCTORS AND Ph. D.) AND LEADING SCIENTIFIC SCHOOLS

2020 ◽  
pp. 59-67
Author(s):  
N.A. Mironov ◽  
E.A. Maryshev ◽  
N.A. Divueva
Keyword(s):  
Information System ◽  
Russian Federation ◽  
Technical Support ◽  
Examination System ◽  
State Support ◽  
New Approaches ◽  
Wide Range ◽  
Integrated Information System ◽  
The Russian Federation ◽  
Integrated Information

The article discusses the issues of improving the examination system of competitive applications for state support in the form of grants of the President of the Russian Federation on the basis of an integrated information system that includes the information support system of the Grants Council of the President of the Russian Federation and the information system of the Federal Roster of Scientific and Technological Experts and containing information about experts, applications and expert examination results. In order to improve the principles of transparency and openness of support programs and competition winners, to ensure the objectivity of the competitive selection of projects, a number of organizational and technical solutions are proposed in the application examination system based on an integrated information system. The new and proposed new approaches to the organizational and technical support of the examination of competitive applications for state support in the form of grants of the President of the Russian Federation to young Russian scientists made it possible, by attracting a wide range of scientific and technological communities, to conduct examination of more than five thousand applications with high quality and deadlines set by the Ministry of Education and Science of Russia.

Cucurbitacins as Anticancer Agents: A Patent Review

2019 ◽  
Vol 14 (2) ◽  
pp. 133-143 ◽  
Author(s):  
Hidayat Hussain ◽  
Ivan R. Green ◽  
Muhammad Saleem ◽  
Khanzadi F. Khattak ◽  
Muhammad Irshad ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Wide Spectrum ◽  
Biological Effects ◽  
Therapeutic Effects ◽  
Cytotoxic Effects ◽  
Natural Sources ◽  
Oh Groups ◽  
Drug Candidates ◽  
The Past ◽  
Wide Range

Background: Cucurbitacins belong to a group of tetracyclic triterpenoids that display a wide range of biological effects. In the past, numerous cucurbitacins have been isolated from natural sources and many active compounds have been synthesized using the privileged scaffold in order to enhance its cytotoxic effects. Objective: his review covers patents on the therapeutic effects of natural cucurbitacins and their synthetic analogs published during the past decade. By far, the majority of patents published are related to cancer and Structure-Activity Relationships (SAR) of these compounds are included to lend gravitas to this important class of natural products. Methods: The date about the published patents was downloaded via online open access patent databases. Results: Cucurbitacins display significant cytotoxic properties, in particular cucurbitacins B and D which possess very potent effects towards a number of cancer cells. Numerous cucurbitacins isolated from natural sources have been derivatized through chemical modification at the C(2)-OH and C(25)- OH groups. Most importantly, an acyl ester of the C(25)-OH and, iso-propyl, n-propyl and ethyl ether groups of the C(2)-OH demonstrated the most increased cytotoxic activity. Conclusion: The significant cytotoxic effects of natural and semi-synthetic cucurbitacins make them attractive as new drug candidates. Moreover, cucurbitacins have the capability to form conjugates with other anticancer drugs which will synergistically enhance their anticancer effects. The authors believe that in order to get lead compounds, there should be a greater focus on the synthesis of homodimers, heterodimers, and halo derivatives of cucurbitacins. In the opinion of the authors the analysis of the published patents on the cucurbitacins indicates that these compounds can be developed into a regimen to treat a wide spectrum of cancers.

scholarly journals Greater trochanteric pain syndrome: Evaluation and management of a wide spectrum of pathology

2021 ◽  
Vol 9 ◽  
pp. 205031212110225
Author(s):  
Mark A Pianka ◽  
Joseph Serino ◽  
Steven F DeFroda ◽  
Blake M Bodendorfer
Keyword(s):  
Wide Spectrum ◽  
Pain Syndrome ◽  
Operative Management ◽  
Hip Pain ◽  
Greater Trochanteric Pain Syndrome ◽  
Trochanteric Bursitis ◽  
Treatment Indications ◽  
Careful Clinical Examination ◽  
Wide Range ◽  
Tendon Pathology

Greater trochanteric pain syndrome is a common cause of lateral hip pain, encompassing a spectrum of disorders, including trochanteric bursitis, abductor tendon pathology, and external coxa saltans. Greater trochanteric pain syndrome is primarily a clinical diagnosis, and careful clinical examination is essential for accurate diagnosis and treatment. A thorough history and physical exam may be used to help differentiate greater trochanteric pain syndrome from other common causes of hip pain, including osteoarthritis, femoroacetabular impingement, and lumbar stenosis. Although not required for diagnosis, plain radiographs and magnetic resonance imaging may be useful to exclude alternative pathologies or guide treatment of greater trochanteric pain syndrome. The majority of patients with greater trochanteric pain syndrome respond well to conservative management, including physical therapy, non-steroidal anti-inflammatory drugs, and corticosteroid injections. Operative management is typically indicated in patients with chronic symptoms refractory to conservative therapy. A wide range of surgical options, both open and endoscopic, are available and should be guided by the specific etiology of pain. The purpose of this review is to highlight pertinent clinical and radiographic features used in the diagnosis and management of greater trochanteric pain syndrome. In addition, treatment indications, techniques, and outcomes are described.

scholarly journals MXenes for future nanophotonic device applications

Nanophotonics ◽  
2020 ◽  
Vol 9 (7) ◽  
pp. 1831-1853
Author(s):  
Jaeho Jeon ◽  
Yajie Yang ◽  
Haeju Choi ◽  
Jin-Hong Park ◽  
Byoung Hun Lee ◽  
...  
Keyword(s):  
Solar Cells ◽  
Transition Metal ◽  
Wide Spectrum ◽  
Building Blocks ◽  
Optoelectronic Device ◽  
High Yield ◽  
Saturable Absorption ◽  
Nanophotonic Device ◽  
Wide Range ◽  
Device Applications

AbstractTwo-dimensional (2D) layers of transition metal carbides, nitrides, or carbonitrides, collectively referred to as MXenes, are considered as the new family of 2D materials for the development of functional building blocks for optoelectronic and photonic device applications. Their advantages are based on their unique and tunable electronic and optical properties, which depend on the modulation of transition metal elements or surface functional groups. In this paper, we have presented a comprehensive review of MXenes to suggest an insightful perspective on future nanophotonic and optoelectronic device applications based on advanced synthesis processes and theoretically predicted or experimentally verified material properties. Recently developed optoelectronic and photonic devices, such as photodetectors, solar cells, fiber lasers, and light-emitting diodes are summarized in this review. Wide-spectrum photodetection with high photoresponsivity, high-yield solar cells, and effective saturable absorption were achieved by exploiting different MXenes. Further, the great potential of MXenes as an electrode material is predicted with a controllable work function in a wide range (1.6–8 eV) and high conductivity (~104 S/cm), and their potential as active channel material by generating a tunable energy bandgap is likewise shown. MXene can provide new functional building blocks for future generation nanophotonic device applications.

scholarly journals Recent Advances in Fabrication of Non-Isocyanate Polyurethane-Based Composite Materials

Materials ◽  
2021 ◽  
Vol 14 (13) ◽  
pp. 3497
Author(s):  
Piotr Stachak ◽  
Izabela Łukaszewska ◽  
Edyta Hebda ◽  
Krzysztof Pielichowski
Keyword(s):  
Raw Materials ◽  
Synthesis Method ◽  
Polymeric Materials ◽  
Original Research ◽  
Significant Group ◽  
Oh Groups ◽  
New Class ◽  
Hazardous Chemical ◽  
Wide Range

Polyurethanes (PUs) are a significant group of polymeric materials that, due to their outstanding mechanical, chemical, and physical properties, are used in a wide range of applications. Conventionally, PUs are obtained in polyaddition reactions between diisocyanates and polyols. Due to the toxicity of isocyanate raw materials and their synthesis method utilizing phosgene, new cleaner synthetic routes for polyurethanes without using isocyanates have attracted increasing attention in recent years. Among different attempts to replace the conventional process, polyaddition of cyclic carbonates (CCs) and polyfunctional amines seems to be the most promising way to obtain non-isocyanate polyurethanes (NIPUs) or, more precisely, polyhydroxyurethanes (PHUs), while primary and secondary –OH groups are being formed alongside urethane linkages. Such an approach eliminates hazardous chemical compounds from the synthesis and leads to the fabrication of polymeric materials with unique and tunable properties. The main advantages include better chemical, mechanical, and thermal resistance, and the process itself is invulnerable to moisture, which is an essential technological feature. NIPUs can be modified via copolymerization or used as matrices to fabricate polymer composites with different additives, similar to their conventional counterparts. Hence, non-isocyanate polyurethanes are a new class of environmentally friendly polymeric materials. Many papers on the matter above have been published, including both original research and extensive reviews. However, they do not provide collected information on NIPU composites fabrication and processing. Hence, this review describes the latest progress in non-isocyanate polyurethane synthesis, modification, and finally processing. While focusing primarily on the carbonate/amine route, methods of obtaining NIPU are described, and their properties are presented. Ways of incorporating various compounds into NIPU matrices are characterized by the role of PHU materials in copolymeric materials or as an additive. Finally, diverse processing methods of non-isocyanate polyurethanes are presented, including electrospinning or 3D printing.

A Review on Meropenem

2021 ◽  
pp. 5034-5038
Author(s):  
Mohsina Abed ◽  
Sara Yousuf
Keyword(s):  
Intravenous Administration ◽  
Wide Spectrum ◽  
Gastrointestinal Haemorrhage ◽  
The Body ◽  
Antibacterial Drug ◽  
Bacterial Strains ◽  
Enhanced Absorption ◽  
Bacterial Cell Death ◽  
Wide Range ◽  
Synthetic Derivative

Meropenem is a new Carbapenem antibacterial agent with wide spectrum of activity for intravenous administration. It is synthetic derivative of Thienamycin. Three analogues of Meropenem are evaluated and active against 18 bacterial strains. Meropenem causes rapid bacterial cell death by covalently binding to penicillin binding proteins (PBS). Structural modification at C-2 position, produced double promoiety prodrug of Meropenem and increases bioavailability of oral administration. Other forms of drug such as liposome and nanoparticles are also available with enhanced absorption. 14C labelled Meropenem prepared from 14C Dimethylamine hydrochloride is used for the analysis of M. tuberculosis transpeptidase. ICI213,689 is the only metabolite of Meropenem and it is inactive. Meropenem penetrates well into the body fluids and tissues including cerebrospinal fluid. Its bioavailability is 100% on intravenous administration. Hence it is used in the treatment of meningitis, febrile neutropenia, anthrax and various other skin and skin structure infections. Dosage reduction is required in patient with reduced renal function but not in hepatic impairment. Seizures, gastrointestinal haemorrhage are observed in patients. Vabmoere is the combination of Meropenem and Vaborbactam which is active against the Carbapenem resistant Enterobacteriacea. Meropenem is an effective broad-spectrum antibacterial drug for the treatment of wide range of infection including polymicrobial infection in both children and adult.

A Comprehensive Assessment Tool for Patient Registry Software Systems: The CIPROS Checklist

2015 ◽  
Vol 54 (05) ◽  
pp. 447-454 ◽  
Author(s):  
U. Mansmann ◽  
D. Lindoerfer
Keyword(s):  
Systematic Review ◽  
Critical Appraisal ◽  
Assessment Tool ◽  
Wide Spectrum ◽  
Patient Registry ◽  
Software Systems ◽  
Software System ◽  
Review Of The Literature ◽  
Patient Registries ◽  
Wide Range

SummaryBackground: Patient registries are an important instrument in medical research. Often their structure is complex and their implementation uses composite software systems to meet the wide spectrum of challenges.Objectives: For the implementation of a registry, there is a wide range of commercial, open source, and self-developed systems available and a minimal standard for the critical appraisal of their architecture is needed.Methods: We performed a systematic review of the literature to define a catalogue of relevant criteria to construct a minimal appraisal standard.Results: The CIPROS list is developed based on 64 papers which were found by our systematic review. The list covers twelve sections and contains 72 items.Conclusions: The CIPROS list supports developers to assess requirements on existing systems and strengthens the reporting of patient registry software system descriptions. It can be a first step to create standards for patient registry software system assessments.

Investigation on a Type of Flow Control to Weaken Unsteady Separated Flows by Unsteady Excitation in Axial Flow Compressors

2004 ◽  
Author(s):  
Xin-Qian Zheng ◽  
Xiao-Bo Zhou ◽  
Sheng Zhou
Keyword(s):  
Wide Spectrum ◽  
Excitation Frequency ◽  
Axial Flow ◽  
Maximum Velocity ◽  
Excitation Amplitude ◽  
High Order Scheme ◽  
Wide Range ◽  
Optimal Excitation ◽  
Suction And Blowing ◽  
Axial Flow Compressors

By solving unsteady Reynolds-averaged 2-D N-S equations discretized by a high-order scheme, the results showed that the disordered unsteady separated flow could be effectively controlled by periodic suction and blowing in a wide range of incidence, resulting in enhancement of time-averaged aerodynamic performances. The effects of unsteady excitation frequency, amplitude and excitation location were investigated in detail. The effective excitation frequency spans a wide spectrum and there is an optimal excitation frequency that is nearly equal to the Characteristic frequency of vortex shedding. Excitation amplitude exhibits a threshold value (nearly 10% in term of the ratio of maximum velocity of periodic suction and blowing to the velocity of free flow) and an optimal value (nearly 35%). The optimal excitation location is just upstream of the separation point. We also explored feasible unsteady actuators by utilizing upstream wake for constraining unsteady separation in axial flow compressors.

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