scholarly journals EFFICIENCY OF THE COMPLEX DRUG CYSTODEZ-ULTRA AGAINST EIMERIA SPP. OOCYSTS IN BROILER CHICKENS

2021 ◽  
pp. 462-468
Author(s):  
Safiullin ◽  
Shibitov ◽  
Chalysheva

The practice of successful poultry farms shows that the prevention of poultry parasitoses includes a complex of therapeutic and prophylactic measures aimed both against exogenous oocysts in the environment and against endogenous stages of the pathogen inside the bird's body with the use of modern antiparasitic drugs. In view of the foregoing and special resistance of Eimeria oocysts in the environment, it is possible to create an effective disinfectant against them using several active ingredients and excipients. Among these drugs, we should note glutaraldehyde, crystalline iodine and potassium iodide when used together at optimal concentrations. The experiments were carried out from August to October 2019 in the laboratory and vivarium of the Institute on 60 14-day-old Cobb-500 broiler chickens. Working solutions of Cystodez-ultra in different concentrations were prepared in advance, as well as a buffer solution WSH for preserving bird feces. Cystodez-ultra is a complex drug in a liquid form for disinfection of veterinary supervision objects and prevention of invasive diseases of birds. In the test, the chickens of the first, second and third groups were administered 1 ml of a suspension of Eimeria spp. oocysts treated with 3, 4 and 5% solutions of Cystodez-ultra orally using a micropipette; the fourth group was also administered 1 ml of a suspension of Eimeria oocysts treated with Phenol solution 4%. Broilers of the fifth group were administered a suspension with sporulated Eimeria spp. oocysts at a dose of 2000 per 1 ml not treated with a disinfectant - the infected control, and the sixth group 1 ml of WSH buffer solution - non-infected control. During the experiment, the chickens were followed up daily paying attention to their general condition, behavior, appetite, and visible physiological changes. According to the study results, the intense-effectiveness of Cystodez-ultra in 3, 4 and 5% concentration against sporulated Eimeria oocysts was 93.08, 100 and 100%, respectively, and Phenol in 4% concentration 76.92%. The number of oocysts in 1g of feces in the infected control was 4680 specimens, and the chickens of the uninfected control remained free from the invasion at all times of the study.

2021 ◽  
Vol 15 (4) ◽  
pp. 106-117
Author(s):  
R. T. Safiullin ◽  
E. O. Kachanova ◽  
E. I. Chalysheva

The purpose of the research is developing a method for disinfection of environmental objects against coccidia oocysts in broiler chickens.Materials and methods. At the VNIIP – FSC VIEV vivarium, a bioassay test was performed to experimentally infect 60 chickens aged 14 days which were divided into six equivalent groups of 10 birds each and kept isolated in cages. Chickens from the first, second and third groups were administered orally, using a micropipette, 1 ml of an Eimeria oocyst suspension treated with 4, 5 and 6% solutions of the combined eimeriocide agent. Chickens from the fourth group were administered 1 ml of Eimeria oocyst suspension treated with 4% phenol solution (base drug). Chickens from the fifth group received 1 ml of a buffered solution and were used as a noninfected control. Chickens from the sixth group received 1 ml of suspension containing 2000 oocysts/mL and were used as an infected control. The efficacy of disinfection with eimeriocide and the basic drug was determined based on the percentage of decrease in the recovery of Eimeria oocysts after being exposed to drugs as compared to chickens of the infected control. The efficacy of 5% eimeriocide against poultry coccidia oocysts in a production test was determined empirically with the set of oocysts on control sites as compared with the basic drug on a poultry farm in the Moscow Region.Results and discussion. The intense-effectiveness of 4% eimeriocide against coccidia oocysts was 99.31%, and the 5 and 6% combined agent showed 100% efficacy. The basic drug, 4% phenol showed 74.65% intense-effectiveness. The results obtained in the production test of 5% eimeriocide at a dose of 0.5 l per 1 m2 with a 2 hour-exposure indicate its high efficacy for disinfection against coccidia oocysts in broiler chickens. The intense-effectiveness was 97.25% versus 59.03% efficacy of the base drug, phenol.


2020 ◽  
pp. 361-367
Author(s):  
Rinat Safiullin ◽  
Chalysheva ◽  
Krasnobayev

The production culture in industrial poultry has risen to a high level and continues to improve in recent years. Profitability of production is the main task of poultry farming, as for any industrial branch. This is due to the intensification of production, a reduction in the period of sanitary preparation of premises, and a high concentration of poultry stock on a limited area. These conditions contribute to the spread of parasitic diseases and eimeriosis is the leading among them. The experiments were carried out on 14-day-old Cobb-500 cross broiler chickens in the laboratory and vivarium of the institute in 2019. First, Virukill 260 working solutions in different concentrations, WSH buffer solution, and bird feces preservative were prepared. Virukill is a multicomposite drug in the form of a liquid, this medicine is used to disinfect and disinfestation objects of veterinary surveillance and the prevention of infectious and invasive animal diseases. Chickens of the first, second and third groups were assigned 1 ml of a suspension of Eimeria oocysts treated with 0.5; 1 and 2% solutions of the drug Virukill 260, inside using a micropipette; the fourth - also 1 ml of a suspension of Eimeria oocysts treated with a 4% phenol solution. Young animals of the fifth group were injected with sporulated Eimeria oocysts at a dose of 2000 / ml of a suspension not treated with a disinfectant (infected control); and the sixth - only 1 ml of WSH buffer solution (uninfected control). The chickens were subjected to daily clinical observations, taking into account the general condition, behavior, appetite, visible physiological changes throughout the experiment. The intensity of Virukill 260 in 0.5-, 1- and 2% concentrations against coccidium oocysts was 94.15; 97.6 and 98.17%, respectively, and phenol at 4% concentration was 88.75%. The following Eimeria species were identified: Eimeria acervulina (21.4%), E. brunetti (15.7%), E. maxima (29.6%) and E. tenella (33.3%) in broiler litter samples from the first to the fifth group.


Author(s):  
Pavel F. Kiku ◽  
Evgeniy V. Zhovnerchuk ◽  
Irina P. Melnikova ◽  
Natalya I. Izmerovа ◽  
Kseniya M. Sabirova

Introduction.Occupational environment and occupational factors determine peculiarities in mastering marine occupations. Some unfavorable occupational educational and ecologic factors appear to cause high level of physical and psychoemotional stress.Objectiveis to study features of adaptation to study during occupational training in marine specialties in cadets of a higher marine educational institution, and to conduct medical and psychological rehabilitation.Material and methods.Examination covered 120 male cadets of 3rd and 4thyears of study: 70 (main group) and 50 (reference group). The age of the cadets was 21±0.4 years. To study characteristics of the cadets’ adaptation, the authors used psychological methods — Spielberger’s State Trait Anxiety Scale and Nemchin’s «Method measuring severity of neuropsychic stress». Statistical analysis was performed with software «Statistica for Windows 10.0».Study results and discussion.After 3 months of sailing, majority of the cadets appeared to be dysadapted. Deep clinical and laboratory studies proved that 39.4% of the examinees were apparently healthy and 60.6% of those had chronic diseases. Thus, a system of medical psychologic rehabilitation was designed, comprising primary and secondary prophylaxis methods. One of these prevention methods is a recovery complex of measures with intermittent normobaric hypoxia modified by us. The authors determined optimal regime of using intermittent normobaric hypoxia combined with medical rehabilitation.Conclusions.Adaptational state in cadets of high marine educational institution during professional training in marine occupations is characterized by increased psycho-emotional strain, anxiety and observed in 57.3% of the examinees. Findings are that after 3 months of sailing, majority of the cadets are dysadapted. To prevent morbidity and preserve health, the authors suggested a system of medical and psychologic rehabilitation including intermittent normobaric hypoxia with rehabilitation medical complex. The medical and prophylactic measures help to solve problems of psycho-emotional stress, lower morbidity parameters, prevent dysadaptation disorders, relieve functional overstrain. That preserves and improves the cadets’ health and forms an important stage in prevention of mental and behavioral disorders related to work.


2021 ◽  
pp. 101329
Author(s):  
Emanuel Gumina ◽  
Jeffrey W. Hall ◽  
Bruno Vecchi ◽  
Xochitl Hernandez-Velasco ◽  
Brett Lumpkins ◽  
...  

2015 ◽  
Vol 74 (1) ◽  
Author(s):  
Mahmood Shirzad ◽  
Abbasali Karimi ◽  
Seyed Hossein Ahmadi ◽  
Mehrab Marzban ◽  
Mokhtar Tazik ◽  
...  

Background: During last decades mechanical ventilation has been an important support in the postoperative management of patients undergoing cardiac surgery. This study was designed to determine the predictors of prolonged mechanical ventilation (PMV) in patients undergoing heart valve surgery. Methods: This retrospective study considered of 1056 patients who underwent isolated valve surgery at Tehran Heart Center from March 2002 to March 2009. PMV is considered as mechanical ventilation period of ≥24 hours at postoperative hospital stay in this study. Results: PMV occurred in 6.6% of patients. Initial ventilation hours, atrial fibrillation, cardiac arrest and reintubation were the most prevalent postoperative complications. Preoperative renal failure, postoperative stroke, intra aortic balloon pump insertion, emergent operation, complete heart block, longer perfusion time were independent predictors of PMV in our patients. Conclusion: PMV is associated with significant comorbidities and increased hospital mortality. Strategies to delineate the patients at risk and to modify these risk factors by prophylactic measures should probably lead to a lower incidence of prolonged mechanical ventilation for patients undergoing isolated valve surgery.


2011 ◽  
Vol 40 (6) ◽  
pp. 1372-1380
Author(s):  
Valéria Maria Nascimento Abreu ◽  
Doralice Pedroso de Paiva ◽  
Paulo Giovanni de Abreu ◽  
Arlei Coldebella

It was evaluated the quality of rice husks or soybean straw as litter substrate and the effect of litter reuse for four consecutive flocks of broiler chickens on populations of darkling beetle and intestinal parasite and as organic fertilizer. The experiment was carried out in four 12 m × 10 m poultry houses, internally divided in 4 boxes/poultry house with 200 birds/pen for four consecutive flocks, each flock with a duration of 42 days and with a 15-day downtime between flocks. The evaluated treatments were two ventilation systems (stationary or oscillating fans) and two litter materials (soybean straw or rice husks). Darkling beetle population was followed by collecting the insects in traps, three traps per box, and endoparasite litter contamination was determined by eggs/oocyst counts per gram of litter. Levels of dry matter, total nitrogen, total phosphorus, potassium, copper, zinc, manganese, iron, organic carbon and pH were evaluated by physical/chemical analyses of samples of the litters in each flock. Overall, litters of broilers used by three flocks meet the minimal legal requirements to be marketed as simple organic fertilizer, regardless to the material used as substrate. Soybean straw presented higher darkling beetle counts in stationary ventilation system as well as in oscillating ventilation system. The probability of rice husks litter present contamination by Eimeria spp oocysts is 18.78 times higher in rice husks than in soybean straw litter when both are submitted to oscillating ventilation, and 1.32 higher when stationary ventilation is used. Litter temperature does not influence significantly levels of contamination by oocysts.


2021 ◽  
pp. 60-64
Author(s):  
L.F. Kaskova ◽  
V.A. Honcharenko

The aim of our study was to find out the effect of our proposed treatment and prevention complex, which included oral administration of «Kvertulin» complex drug, «Imupret» drops, «Pikovit» multivitamin drug and «Exodent» local irrigation of the oral cavity with a solution of tooth elixir that influence on the rate of salivation and viscosity of oral fluid in children with chronic catarrhal gingivitis and diabetes mellitus.The treatment and prophylactic measures had positive effect on the homeostasis of the oral cavity, which assisted to reduce the viscosity of the oral fluid, increase the rate of salivation, as evidenced by observation of patients for 6 months. The treatment and prevention complex are recommended to use 2 times a year, as the studied indicators deteriorate over time.


2020 ◽  
Vol 7 ◽  
Author(s):  
Tatiane Souza dos Santos ◽  
Po-Yun Teng ◽  
Sudhir Yadav ◽  
Fernanda Lima de Souza Castro ◽  
Rebecca Lizabeth Gould ◽  
...  

2019 ◽  
Vol 7 (3) ◽  
pp. 71 ◽  
Author(s):  
Cristiano Bortoluzzi ◽  
Bruno Serpa Vieira ◽  
Juliano Cesar de Paula Dorigam ◽  
Anita Menconi ◽  
Adebayo Sokale ◽  
...  

The objective of this study was to evaluate the effects of the dietary supplementation of Bacillus subtilis DSM 32315 (probiotic) on the performance and intestinal microbiota of broiler chickens infected with Clostridium perfringens (CP). One-day-old broiler chickens were assigned to 3 treatments with 8 replicate pens (50 birds/pen). The treatments were: non-infected control; infected control; and infected supplemented with probiotic (1 × 106 CFU/g of feed). On day of hatch, all birds were sprayed with a coccidia vaccine based on the manufacturer recommended dosage. On d 18–20 the infected birds were inoculated with CP via feed. Necrotic enteritis (NE) lesion score was performed on d 21. Digestive tract of 2 birds/pen was collected on d 21 to analyze the ileal and cecal microbiota by 16S rRNA sequencing. Performance was evaluated on d 28 and 42. On d 21, probiotic supplementation reduced (p < 0.001) the severity of NE related lesion versus infected control birds. On d 28, feed efficiency was improved (p < 0.001) in birds supplemented with probiotic versus infected control birds. On d 42, body weight gain (BW gain) and feed conversion ratio (FCR) were improved (p < 0.001) in probiotic supplemented birds versus infected control birds. The diversity, composition and predictive function of the intestinal microbial digesta changed with the infection but the supplementation of probiotic reduced these variations. Therefore, dietary supplementation of Bacillus subtilis DSM 32315 was beneficial in attenuating the negative effects of CP challenge on the performance and intestinal microbiota of broilers chickens.


2008 ◽  
Vol 32 (2) ◽  
pp. 147-158
Author(s):  
Dalia Ahmed Kalef

To conduct the influence of salinomycin & anticoccidial vaccine onpathological changes in intestine of broiler chickens experimentalinfected with Eimeria spp. By using 40 broiler chicks divided randomlyto four groups( 10 chicks of each group ) First group vaccinated withanticoccidial vaccine (coccivac) at 8 days of age in drinking water whilethe second group feeded salinomycin in concentration 60ppm from oneday old ,the third group left non vaccinated nor given salinomycin as acontrol group at(26 days )of age chicks in that three groups infected withdifferent species of Eimeria spp .with high dose (744x74³) Oocyst /chickby group inoculation & the fourth group consider negative control notvaccinated or treated .At (33 days)of chicks age all the chicks were killedfor measuring lesion score of intestine which their results +1.75 , +3, +4with mortality rate 0%,10%,20% for vaccinated ,salinomycine treated &control groups respectively then took samples for Histopathologicalchanges the results pointed high pathological changes in intestine ofpositive control group with sever necrosis & degeneration of epitheliawith sever tissue damage companied with maturation first & secondgeneration sporozoite in the endothelial layer of intestine. While thepathological changes was less sever in salinomycine treated group withnecrosis & degeneration of epithelial layers accompanied with exist ofsporozoite in endothelial layer of intestine . while the vaccinated groupshowed no clear pathological changes in intestine except hyperplasia ofglobal cells & infiltration of lymphocytes cells in the layers of intestine ,it was concluded that the vaccine which was given to chicks provide goodprotection & decrease dangerous of coccidiosis infection .


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