scholarly journals INFLUENCE OF THE TREATMENT AND PREVENTIVE MEASURES ON THE PHYSICAL INDICATORS OF ORAL LIQUID IN CHILDREN WITH CHRONIC CATARRHIC GINGIVITIS AND DIABETES MELLITUS

2021 ◽  
pp. 60-64
Author(s):  
L.F. Kaskova ◽  
V.A. Honcharenko
Keyword(s):  
Diabetes Mellitus ◽  
Oral Cavity ◽  
Oral Fluid ◽  
Preventive Measures ◽  
Treatment And Prevention ◽  
Prophylactic Measures ◽  
Oral Liquid ◽  
Positive Effect ◽  
Over Time ◽  
Complex Drug

The aim of our study was to find out the effect of our proposed treatment and prevention complex, which included oral administration of «Kvertulin» complex drug, «Imupret» drops, «Pikovit» multivitamin drug and «Exodent» local irrigation of the oral cavity with a solution of tooth elixir that influence on the rate of salivation and viscosity of oral fluid in children with chronic catarrhal gingivitis and diabetes mellitus.The treatment and prophylactic measures had positive effect on the homeostasis of the oral cavity, which assisted to reduce the viscosity of the oral fluid, increase the rate of salivation, as evidenced by observation of patients for 6 months. The treatment and prevention complex are recommended to use 2 times a year, as the studied indicators deteriorate over time.

scholarly journals Clinical and immunologic assessment of a complex of therapeutic-preventive measures concerning chronic catarrhal gingivitis in children with comorbid diabetes mellitus

2020 ◽  
Vol 73 (2) ◽  
pp. 298-301
Author(s):  
Oksana I. Godovanets ◽  
Аnastasiia V. Kotelban ◽  
Petro V. Moroz ◽  
Oleksandr O. Vitkovskyi ◽  
Tetiana S. Kitsak ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Oral Fluid ◽  
Preventive Measures ◽  
Main Group ◽  
Antiseptic Solution ◽  
Similar Tendency ◽  
Group A ◽  
Comparative Group ◽  
The Common

The aim of our study is to increase the efficacy of treatment of chronic catarrhal gingivitis in children suffering from type 1 diabetes mellitus by means of improvement of the methods of pharmacological correction on the basis of investigation of clinical-immunologic peculiarities of the disease. Materials and methods: 2 groups of the study were formed. Children received basic insulin therapy. The treatment of chronic catarrhal gingivitis in children from the main group were suggested the antiseptic solution “Decasan”; pill of a probiotic action “BioGaia ProDentis” and the immune modulator “Imupret”. Children from the comparative group were treated according to the common scheme. Results: The state of the oral hygiene in all the children after treatment improved considerably. According to PMA index inflammatory process was completely eliminated in children from the main group. A similar tendency was observed concerning sextants with gingival bleeding. In children dental calculus was lacking after treatment. Lysozyme activity in the oral fluid of children after treatment increased approximately 37.50% in the main group, and 16,67 % – in the comparison group. A similar tendency was found concerning sIgА level. Conclusions: Therefore, conducted course of the treatment concerning chronic catarrhal gingivitis promoted considerable improvement of the periodontal tissue in children.

scholarly journals COMPARISON OF SALIVATION RATE AND VISCOSITY OF ORAL LIQUID IN ADOLESCENTS 15-18 YEARS OLD WITH CARIES, WHO STUDY IN DIFFERENT EDUCATIONAL ESTABLISHMENTS

2021 ◽  
pp. 67-71
Author(s):  
L.F. Kaskova ◽  
I.I. Drozda ◽  
L.P. Ulasevych
Keyword(s):  
College Students ◽  
Oral Cavity ◽  
The State ◽  
Considerable Influence ◽  
Microbial Composition ◽  
Caries Activity ◽  
Reliable Difference ◽  
Prophylactic Measures ◽  
Hard Tissues ◽  
Oral Liquid

Caries is the most widespread stomatological disease among children, teenagers, and adults. After their eruption, hard tooth tissues are under the constant influence of oral liquid, property, and composition of which constantly change under the influence of different factors, such as local and general. Local and general factors, among which there is the state of hygiene of oral cavity, presence of somatic pathologies, psycho-emotional state of patient and others, influence the indexes of oral liquid. Considerable influence of the development of pathology of hard tissues has increased the secretion of saliva, its viscosity. Worsening of these indexes speeds the formation of dental plaque and change of its microbial composition, which, in turn, results in the demineralization of enamel. Therefore, a study of the speed of salivation and viscosity of mouth liquid in teenagers with caries is a pressing problem for the further planning of prophylactic measures in them. Undertaken studies of the speed of salivation certify the difference of indexes for teenagers, that study in different establishments of education. Thus, among 15 and 16-years-old teenagers that attend school an index was higher for schoolchildren as compared to the college students (p0,01), which could be explained by better stomatological status for them: the school attenders had the compensated degree of activity of caries, and college students ̶ compensated, subcompensated and decompensated. For schoolchildren speed of salivation improves from the age of 15 to 16 (p0,01), and for the students of the college, it remains almost at the same level. Students of university at 17 and 18 years had an index of the speed of salivation, that met a standard and did not have a reliable difference in different age-old periods, but had a reliable difference when compared to the index of college students. Speed of salivation for college attenders decreased with age and had the worst result in 18 years old. Leaning on the obtained data, there is ap necessity of the study of this index, according to the degree of activity of caries. From all examined patients, the best index of the speed of salivation was in teenagers with the compensated degree of caries activity, the worst  ̶ in decompensated. The students of different educational establishments have the educed reliable difference of speed of salivation. The worst indexes were found in the examined college students, regardless of the degree of caries activity. The received results need a more detailed study of the reasons of origin of the cariogenic situation of this contingent of teenagers. The viscosity of oral liquid has a considerable influence on the state of the hard tissues of teeth. Its increase results in the considerable accumulation of dental stratifications, increase in the amount of microflora that results in focal demineralization. We found the dependence of this index on the degree of caries activity in attenders of different educational establishments. The viscosity of the oral liquid increases with the increase of index of intensity of caries and reaches a maximum for teenagers with the decompensated degree of caries activity. The worst index is found in college students with the decompensated degree of caries activity. Even at the identical degree of caries activity, the viscosity of mouth liquid in teenagers, that study in a college is higher than in those, who attend school or university. The received results of research need a more detailed study of factors that influence on the origin of the cariogenic situation in the mouth cavity for college students. The results of our research testify to the presence of the highly expressed cariogenic situation in the oral cavity of teenagers, that study in a college that is expressed in the decline of the index of the speed of salivation and increase of viscosity of the oral liquid. Indexes that were studied deteriorate depending on age and degree of caries activity, and reach the maximum in 18-years-old college students. Both, speed of salivation and viscosity of oral liquid were the worst in teenagers with the decompensated degree of caries activity. The received results have to be directed for the development of prophylactic measures at this contingent to increase the resistance of hard tooth tissues for prevention of appearance and development of caries in them.

scholarly journals Дослідження динаміки показників імунного статусу у дітей з множинним карієсом на фоні захворювань шлунково-кишкового тракту у різні терміни лікування

2017 ◽  
Author(s):  
V. I. Rozhko
Keyword(s):  
Gastrointestinal Tract ◽  
Oral Fluid ◽  
Main Group ◽  
Diffusion Method ◽  
Immunological Parameters ◽  
Immunological Status ◽  
Gastrointestinal Lesions ◽  
Prophylactic Measures ◽  
Oral Liquid ◽  
Rampant Caries

The level of immunoglobulins and lysozyme in the oral fluid deviates from the norm at presence of the diseases of the gastrointestinal tract (GI), which is likely to be a trigger in the development of rampant caries in children. A detailed study of this aspect has made it possible to directly influence the inhibition of the pathological process.The aim of the study – to evaluate the effectiveness of the use of a complex of therapeutic and prophylactic measures aimed at increasing the resistance of the oral cavity in children with rampant caries on the background of diseases of the gastrointestinal tract in 12–14 days and 6 months after treatment; compare the data with these before treatment.Materials and Methods. The article presents the results of the study of the dynamics of immunological parameters in children with rampant caries on the background of diseases of the gastrointestinal tract. The increase of the indexes of immunoglobulins A, G, secretory immunoglobulin A, lysozyme in the oral liquid of the children of the main, comparative and control groups was determined by the method of radial immunodiffusion in Mancini agar and agar diffusion method containing 0.05 % biomass powder Micrococcus lysodeikticus.Results and Discussion. As a result of the proposed treatment and prophylactic complex, we managed to achieve a significant improvement in the immunological status of oral fluid in children with rampant caries on the background of GI tract diseases. Thus, after treatment (12–14 days), the content of IgA in the oral liquid of the children of the main group increased by 80.0 % higher in relation to the data before treatment. At the same time, in children of the main group, the decrease in the IgG concentration, which was lower than the data before treatment, was studied at 26.32 %. At 12–14 days after treatment in children with multiple caries, against the background of gastrointestinal lesions of the main group, an increase in sIgA and lysozyme was observed, which was 39.13 % and 23.85 % higher, respectively, for the data before treatment.Conclusions. The complex of therapeutic and prophylactic measures introduced and implemented in clinical practice causes a pronounced caries prophylactic effect and improves the state of hygiene, increases the acidity of the enamel and mineralizing properties of the oral liquid, normalizes microbiocenosis and immunological status, which in general optimizes the processes of remineralization.

scholarly journals FEATURES DENTAL STATUS OF PATIENTS WITH TYPE II DIABETES IN THE HOSPITAL LEVEL

2013 ◽  
Vol 9 (2) ◽  
pp. 34-37 ◽  
Author(s):  
Т. Еловикова ◽  
T. Elovikova ◽  
А. Трошунин ◽  
A. Troshunin ◽  
Е. Жукова ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Secretion ◽  
Oral Cavity ◽  
Type Ii Diabetes ◽  
Insulin Action ◽  
Oral Fluid ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii ◽  
Hospital Level ◽  
Intensity Decay

<p>Diabetes — a group of diseases characterized by hyperglycemia resulting from violations of insulin secretion, insulin action or both. The study revealed the following symptoms of the oral cavity in patients with type II diabetes mellitus: the mucous membrane swollen, pale, dry and shiny, tongue dry, wrinkled and pink, as well as poor hygiene, high intensity decay. Use mouthwash after first use showed significant improvements in the structure of the oral fluid.</p>

scholarly journals MODERN DIAGNOSTICS METHODS OF NON-SPECIFIC PROTECTION OF PERIODONTAL TISSUES IN RESIDENTS OF THE INDUSTRIAL REGION

2020 ◽  
pp. 18-23
Author(s):  
A.V. Samoilenko ◽  
S.V. Pavlov ◽  
I.V. Vozna
Keyword(s):  
Oral Cavity ◽  
Oral Fluid ◽  
Pathological Process ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Study Group ◽  
Periodontal Tissue ◽  
Oral Liquid ◽  
Healthy Control

The aim of the article is to study the peculiarities of antimicrobial immunity of the oral cavity of the industrial region’s inhabitants in order to optimize special preventive programs of major dental diseases. The object and research methods. 178 patients was examined from 21 to 50 years old, who turned to the University Dental Center of Zaporizhzhia State Medical University. The study group consisted of 126 patients with generalized periodontitis of the initial (8), I (32), II (68) and III (18) degree of chronic course, complicated by harmful factors of manufacturing. The comparison group consisted of 32 patients with periodontitis (5), I (10), II (11) and III (6) degrees who did not work in adverse conditions. The control group consisted of 20 relatively healthy individuals aged from 19 to 25 years without signs of generalized periodontitis. To study the factors of local immunity of the oral cavity, oral fluid was collected from each examined person, which was obtained without stimulation, spitting into sterile tubes. Then the oral fluid was centrifuged for 15 minutes at 8,000 rpm. The supernatant part of the oral liquid was poured into plastic tubes and stored at 30°C. The quantitative determination of markers in the oral fluid was performed by standard enzyme immunoassay kits according to the instructions of the "Lactoferrin-strip" ("VectorBest") manufacturers. The result was expressed in mµg / ml. The content of cathelicidin LL-37 was determined by enzyme-linked immunosorbent assay using NycultBiotechhuman LL-37 ELISA (Netherlands) firm reagent kit-manufacturers. The result was expressed in µg / ml. Statistica 13.0 licensed number JPZ804I382130ARCN10-J was used to process the results. The results of the study and their discussion. The hygienic condition in the examined patients of the study group was assessed as unsatisfactory: from 2.24 ± 0.5 to 2.99 ± 0.47 points depending on the age and length of service at the enterprise, but the PI and SBI values were increased. It was found, that the lactoferrin level in the oral fluid was higher in the all patients with periodontitis, than the same index in comparison with healthy control group and consistently increased with increasing severity of the process. In the patients’ study group, working in hazardous conditions of production, the lactoferrin content has increased in the oral fluid relative to the level of the healthy patients was more pronounced in comparison with the patients, suffering of periodontal tissue disease, but do not work in harmful manufacturing conditions. Increased lactoferrin in the oral fluid in the steelmaking workers can be considered as a means of compensation, that provides protection of the oral mucosa from colonization of microorganisms. In the steel industry workers, a statistically significant cathelicidin content decrease in the oral fluid was observed compared to healthy control patients’ group. In the clinical group of the patients without adverse factors of production, the cathelicidin’s concentration in the oral fluid was also reduced. The increasing level of lactoferrin in the oral fluid in parallel with the cathelicidin’s decrease in saliva are markers of the inflammatory phase, as well as the destructive phase of connective tissue. Conclusions. Thus, our observations have established a direct relationship between the lactoferrin’s concentration in the oral fluid and the severity of periodontal tissue diseases and the feedback between the cathelicidin’s content in the oral liquid and the activity of the pathological process. The determination of lactoferrin and cathelicidin in the oral fluid of the patients with harmful manufacturing factors allow us to identify the signs of pathological process in the oral cavity.

Kajian Interaksi Obat Metformin pada Pasien Diabetes Mellitus

2019 ◽  
Vol 8 (2) ◽  
pp. 55-58
Author(s):  
Havizur Rahman ◽  
Teresia Anggi Octavia
Keyword(s):  
Diabetes Mellitus ◽  
Drug Interaction ◽  
Data Collection ◽  
Drug Interactions ◽  
Degenerative Disease ◽  
Moderate Severity ◽  
Purposive Sampling ◽  
Chronic Degenerative Disease ◽  
Over Time ◽  
Diabetes Melitus

Diabetes melitus merupakan penyakit degeneratif kronis yang apabila tidak ditangani dengan tepat, lama kelamaan bisa timbul berbagai komplikasi, ini cenderung menyebabkan pasien mendapatkan banyak obat dalam satu resep yang dapat menimbulkan interaksi antar obat. Tujuan dari penelitian ini adalah mengetahui persentase terjadinya interaksi obat metformin secara teori serta mengkaji efek yang mungkin timbul dan solusinya. Teknik pengambilan data dengan purpossive sampling, yaitu resep pasien rujuk balik yang menderita diabetes mellitus yang menggunakan metformin. Data yang diperoleh ditemukan bahwa obat yang berinteraksi dengan metformin dengan tingkat keparahan minor ialah sebesar 60%. Kemudian untuk tingkat keparahan moderat ialah sebesar 20%. Sedangkan untuk tingkat keparahan mayor tidak ditemukan. Dari tabel diatas juga dapat diketahui bahwa terdapat 4 obat yang saling berinteraksi dengan metformin, sedangkan untuk obat yang tidak saling berinteraksi dengan metformin terdapat 9 obat. Jumlah obat yang berinteraksi secara teori sebesar 6,85% dan yang tidak berinteraksi 93,15%. Terdapat interaksi obat metformin dengan beberapa obat yaitu furosemid, lisinopril, acarbose dan ramipril.   Kata kunci: interaksi obat, metformin, diabetes mellitus   STUDY OF METFORMIN INTERACTION IN MELLITUS DIABETES PATIENTS   ABSTRACT Mellitus is a chronic degenerative disease which if not handled properly, over time can arise various complications, this tends to cause patients to get many drugs in one recipe that can cause interactions between drugs. The purpose of this study is to determine percentage of metformin drug interactions in theory and examine the effects that may arise and solutions. Data collection techniques using purposive sampling, which is a recipe for reconciliation patients who suffer from diabetes mellitus using metformin. The data obtained it was found that drugs that interact with metformin with minor severity were 60%. Then for moderate severity is 20%. Whereas the major severity was not found. From the table above it can also be seen that there are 4 drugs that interact with metformin, while for drugs that do not interact with metformin there are 9 drugs. The number of drugs that interacted theoretically was 6.85% and 93.15% did not interact. An interaction of the drug metformin with several drugs namely furosemide, lisinopril, acarbose and ramipril.   Keywords: drug interaction, metformin, diabetes mellitus

Surveying adherence of dental clinic patients to preventive measures in oral cavity

2019 ◽  
Vol 24 (2) ◽  
pp. 167-172 ◽  
Author(s):  
T. V. Kudryavtseva ◽  
V. V. Tachalov ◽  
E. S. Loboda ◽  
L. Yu. Orekhova ◽  
E. Yu. Nechai ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Working Conditions ◽  
Oral Hygiene ◽  
Preventive Measures ◽  
Periodontal Diseases ◽  
Dental Health ◽  
Developed Countries ◽  
Dental Clinic ◽  
The Many ◽  
The Impact

Relevance. Periodontal diseases are a medical and social problem due to the wide spread among the population of developed countries and the impact on the quality of life. Among the many factors that are important in the development of inflammatory periodontal diseases, an important role is played by adherence to the recommendations of the dentist in respecting oral hygiene. Aim of the work was to study the adherence of patients of the dental clinic to compliance with preventive measures in the oral cavity.Materials and methods. A total of 98 patients of dental clinic, 62 female (medial age 38,6 ± 14,0 years) and 36 male (medial age 37,2±13,1 years) participated in survey. The study participants flled in the profle and answered questions about age, gender, harmful working conditions and bad habits, frequency of visits to the dental clinic, attitudes to the prevention of dental diseases, knowledge about the means and methods of oral hygiene.Results. As a result of the study, it was found that in the vast majority of cases, respondents are employed in production that does not adversely affect their health (91%), only 8% of patients indicated harmful working conditions.Conclusions. The study revealed that, despite the recommendations of the dentist, patients are not always committed to the implementation of preventive measures in the oral cavity. Dentists need to motivate patients to use not only the usual methods and means of hygiene, but also additional ones necessary for maintaining dental health.

ETIOLOGICAL FACTORS OF SQUAMOUS CELL CANCER OF THE MUCOUS MEMBRANE OF THE ORAL CAVITY

2017 ◽  
Vol 63 (5) ◽  
pp. 703-707
Author(s):  
Vladimir Nikolenko ◽  
Yekaterina Kochurova ◽  
Aleksandr Mukhanov
Keyword(s):  
Oral Cavity ◽  
Mucous Membrane ◽  
Squamous Cell ◽  
Preventive Measures ◽  
Causal Relation ◽  
Cell Cancer ◽  
General Assumption ◽  
Etiological Factors ◽  
Long Acting ◽  
Potential Pathogenicity

Modern data of the etiology of squamous cell carcinoma (SCC) of the mucous membrane of the oral cavity (MMOC) show an increasing prevalence of the disease, a high mortality rate despite the development of modern methods of diagnosis and treatment. SCC is a group of polyetiological diseases. Among the most often etiological factors the use of tobacco products is found as one of the main cause of the disease with the division into active or passive methods of their use, prevalence and potential pathogenicity. Also the risk of the development of SCC MMOC depends on the consumption of alcoholic product as the long-acting traumatic factor. There were analyzed and considered the most common precancerous diseases of the mucous membrane of the mouth, their private and common significance in the structure of precancerous diseases. There was revealed the high correlation between periodontal disease and the development of SCC MMOC, which corresponded to the general assumption about the risk of oncology development against the background of chronic infection in the oral cavity. There were identified new data of the relation between the carriers of some types of the viruses of human papillomavirus and the development of SCC MMOC. Particular understanding of the causal relation of presented on-copathology allowed judging the lack of preventive measures, the necessity of required qualification of specialists of dental and related profile.

A Critical Review on Madhumeha (Diabetes Mellitus) with its Preventive Approach

2017 ◽  
Vol 2 (05) ◽  
Author(s):  
Anagha Gosavi ◽  
Ram V. Ramekar
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Secretion ◽  
Protein Metabolism ◽  
Insulin Action ◽  
Preventive Measures ◽  
Sweet Taste ◽  
Whole Body ◽  
Appropriate Use ◽  
Chronic Hyperglycemia ◽  
Therapeutic Measures

Prameha is disease of Mutravaha Srotasa having Kapha dominancy which can be correlated with diabetes mellitus. The term diabetes mellitus describes a metabolic disorder of multiple etiologies characterized by chronic hyperglycemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. Madhumeha is considered as a subtype under the Vatika type of Prameha and it is characterized by passage of urine with sweet taste like honey along with sweetness of whole body. With appropriate use of Ayurvedic preventive measures such as Dincharya, Ritucharya, Aharvidhi and therapeutic measures Madhumeha (DM) can be prevented.

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