scholarly journals Differential effects of pesticides on soil microflora in cultivated soil of Indian rice field agro-ecosystems

2011 ◽  
Vol 3 (2) ◽  
pp. 277-279 ◽  
Author(s):  
Kalyanee Sharma Bhagabati ◽  
Hemen Sarma
Keyword(s):  
Adverse Effect ◽  
Rice Field ◽  
Plant Protection ◽  
Soil Microflora ◽  
High Dose ◽  
Cultivated Rice ◽  
Normal Dose ◽  
Cultivated Soil ◽  
Negative Effect ◽  
Bacteria And Fungi

The present study was carried out to evaluate the effect of indiscriminant use of common pesticides especially insecticide on the population of soil micro flora in cultivated soil of Indian rice field agro-ecosystems. Endosulfan and Dichlorvos @ 1ml/l (normal dose) did not show any adverse effect on soil micro flora; but a high dose 2ml/l showed a negative effect. On the other hand Carbofuran @ 9 kg/acre (normal dose) and 12kg/ acre (high dose) showed an adverse effect on the growth of actinomycetes, bacteria and fungi. The important findings of the present study is that the effect on microbes by applying insecticides reflects the ecological imbalance of microbes in cultivated soil and hamper the microbial equilibrium to some extent. The study focused that the uses of the pesticides as a plant protection agent occasionally hamper the growth of soil micro flora in cultivated rice field.

Associated microflora of medicinal ferns: biotechnological potentials and possible applications

2016 ◽  
Vol 5 (03) ◽  
pp. 4927 ◽  
Author(s):  
Shubhi Srivastava ◽  
Paul A. K.
Keyword(s):  
Secondary Metabolites ◽  
Growth Promotion ◽  
Biological Activities ◽  
Hydrolytic Enzymes ◽  
In Vitro Production ◽  
Wide Range ◽  
Negative Effect ◽  
Bacteria And Fungi

Plant associated microorganisms that colonize the upper and internal tissues of roots, stems, leaves and flowers of healthy plants without causing any visible harmful or negative effect on their host. Diversity of microbes have been extensively studied in a wide variety of vascular plants and shown to promote plant establishment, growth and development and impart resistance against pathogenic infections. Ferns and their associated microbes have also attracted the attention of the scientific communities as sources of novel bioactive secondary metabolites. The ferns and fern alleles, which are well adapted to diverse environmental conditions, produce various secondary metabolites such as flavonoids, steroids, alkaloids, phenols, triterpenoid compounds, variety of amino acids and fatty acids along with some unique metabolites as adaptive features and are traditionally used for human health and medicine. In this review attention has been focused to prepare a comprehensive account of ethnomedicinal properties of some common ferns and fern alleles. Association of bacteria and fungi in the rhizosphere, phyllosphere and endosphere of these medicinally important ferns and their interaction with the host plant has been emphasized keeping in view their possible biotechnological potentials and applications. The processes of host-microbe interaction leading to establishment and colonization of endophytes are less-well characterized in comparison to rhizospheric and phyllospheric microflora. However, the endophytes are possessing same characteristics as rhizospheric and phyllospheric to stimulate the in vivo synthesis as well as in vitro production of secondary metabolites with a wide range of biological activities such as plant growth promotion by production of phytohormones, siderophores, fixation of nitrogen, and phosphate solubilization. Synthesis of pharmaceutically important products such as anticancer compounds, antioxidants, antimicrobials, antiviral substances and hydrolytic enzymes could be some of the promising areas of research and commercial exploitation.

scholarly journals Long-Term Cryopreservation Does Not Affect Quality of Peripheral Blood Stem Cell Grafts: A Comparative Study of Native, Short-Term and Long-Term Cryopreserved Haematopoietic Stem Cells

2021 ◽  
Vol 30 ◽  
pp. 096368972110360
Author(s):  
Daniel Lysak ◽  
Michaela Brychtová ◽  
Martin Leba ◽  
Miroslava Čedíková ◽  
Daniel Georgiev ◽  
...  
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Statistical Significance ◽  
Extended Period ◽  
High Dose ◽  
Atp Production ◽  
Cd34 Cells ◽  
Negative Effect

Cryopreserved haematopoietic progenitor cells are used to restore autologous haematopoiesis after high dose chemotherapy. Although the cells are routinely stored for a long period, concerns remain about the maximum storage time and the possible negative effect of storage on their potency. We evaluated the effect of cryopreservation on the quality of peripheral stem cell grafts stored for a short (3 months) and a long (10 years) period and we compared it to native products.The viability of CD34+ cells remained unaffected during storage, the apoptotic cells were represented up to 10% and did not differ between groups. The clonogenic activity measured by ATP production has decreased with the length of storage (ATP/cell 1.28 nM in native vs. 0.63 in long term stored products, P < 0.05). Only borderline changes without statistical significance were detected when examining mitochondrial and aldehyde dehydrogenase metabolic activity and intracellular pH, showing their good preservation during cell storage. Our experience demonstrates that cryostorage has no major negative effect on stem cell quality and potency, and therefore autologous stem cells can be stored safely for an extended period of at least 10 years. On the other hand, long term storage for 10 years and longer may lead to mild reduction of clonogenic capacity. When a sufficient dose of stem cells is infused, these changes will not have a clinical impact. However, in products stored beyond 10 years, especially when a low number of CD34+ cells is available, the quality of stem cell graft should be verified before infusion using the appropriate potency assays.

Methodology in Accelerated Biodegradation of Herbicides

1987 ◽  
Vol 1 (4) ◽  
pp. 333-340 ◽  
Author(s):  
Ravva V. Subba-Rao ◽  
Thomas H. Cromartie ◽  
Reed A. Gray
Keyword(s):  
Quantitative Measurement ◽  
Microbial Growth ◽  
Soil Microflora ◽  
Chemical Analyses ◽  
Untreated Soil ◽  
Accelerated Degradation ◽  
Field Soils ◽  
Potential Formation ◽  
Bacteria And Fungi ◽  
Additional Index

Accelerated biodegradation of herbicides in soils can be demonstrated in the laboratory either by treating soil samples with a herbicide under conditions favorable for microbial growth or by sampling field soils soon after herbicidal treatment. Quantitative measurement of accelerated degradation of thiocarbamates in field soils is complicated by the difficulty both of obtaining a proper untreated soil and of obtaining a representative sample by proper mixing of treated soil. Both bacteria and fungi degrade thiocarbamate herbicides, and examples of either class of organisms can be isolated by suitable selection and enrichment conditions. The enzymes involved in the initial steps of thiocarbamate biodegradation seem labile and have not been characterized. Studies of accelerated biodegradation of pesticides should measure the disappearance of the parent or active herbicide using chemical analyses or bioassays. Measuring accelerated biodegradation by determining metabolites (including CO2) is complicated by potential formation of other products, by incorporation of radioactivity into soil microflora, and by complex kinetics partly due to co-metabolism of the herbicide. Additional index words: EPTC, butylate.

scholarly journals Is there an adverse effect of sons on maternal longevity?

2009 ◽  
Vol 276 (1664) ◽  
pp. 2081-2084 ◽  
Author(s):  
David Cesarini ◽  
Erik Lindqvist ◽  
Björn Wallace
Keyword(s):  
Adverse Effect ◽  
Original Study ◽  
Compelling Evidence ◽  
Northern Sweden ◽  
Negative Effect ◽  
Study Population ◽  
Larger Sample

Recent years have witnessed the emergence of a literature examining the effects of giving birth to sons on postmenopausal longevity in pre-industrial mothers. The original paper in this lineage used a sample ( n =375) of Sami mothers from northern Finland and found that, relative to daughters, giving birth to sons substantially reduced maternal longevity. We examine this hypothesis using a similar and a much larger sample ( n =930) of pre-industrial Sami women from northern Sweden, who in terms of their demographic, sociocultural and biological conditions, closely resemble the original study population. In contrast to the previously reported results for the Sami, we find no evidence of a negative effect of sons on maternal longevity. Thus, we provide the most compelling evidence to date that the leading result in the literature must be approached with scepticism.

scholarly journals Neuroleptic malignant syndrome following catatonia: Vigilance is the price of antipsychotic prescription

2017 ◽  
Vol 5 ◽  
pp. 2050313X1769599 ◽  
Author(s):  
Thomas J Reilly ◽  
Sean Cross ◽  
David M Taylor ◽  
Richard Haslam ◽  
Sophie C Tomlin ◽  
...  
Keyword(s):  
Adverse Effect ◽  
Adverse Drug Reaction ◽  
Pulmonary Embolism ◽  
Neuroleptic Malignant Syndrome ◽  
Kidney Injury ◽  
Clinical Suspicion ◽  
Antipsychotic Treatment ◽  
High Dose ◽  
Intravenous Fluids ◽  
Life Threatening

Objectives: To describe a case of neuroleptic malignant syndrome following antipsychotic treatment of catatonia, highlighting the potentially serious complications of this rare adverse drug reaction. Methods: We present a case report of a patient who developed this syndrome with various sequelae. Results: The patient developed neuroleptic after being treated with lorazepam and olanzapine for catatonia. He subsequently developed the complications of rhabdomyolysis, acute kidney injury, pulmonary embolism, urinary retention and ileus. He received high-dose lorazepam, anticoagulation and intravenous fluids. Antipsychotic medication in the form of haloperidol was reinstated with no adverse effect, and he went on to make a full recovery. Conclusions: This case illustrates the potential life-threatening complications of neuroleptic malignant syndrome and the need for a low index of clinical suspicion. It also highlights the lack of evidence for treatment of catatonia, including the use of antipsychotics.

​Factors Affecting Production of Important Pulse Crops in Rajasthan: A Cobb Douglas Analysis

2021 ◽  
Author(s):  
Devendra Kumar Verma ◽  
Hari Singh ◽  
Girdhari lal Meena ◽  
Jitendra Suman ◽  
Sharad Sachan
Keyword(s):  
Production Function ◽  
Irrigation Water ◽  
Agricultural Sector ◽  
Plant Protection ◽  
Secondary Data ◽  
Protection Measures ◽  
Factors Affecting ◽  
Pulse Crops ◽  
Human Labour ◽  
Negative Effect

Background: Pulses are one of the most important food crops grown globally owed to their higher protein content. It also accounts for larger financial gains of the agricultural sector by amounting for a large part of the exports. The present study was carried out to determine the factors affecting production of pulse crops in Rajasthan. Methods: This paper based on secondary data collected over the years i.e. from 2000-01 to 2017-18. The Cobb-douglas production function was used to the observation for the estimation of elasticity of selected variables contributing to the production of pulses in Rajasthan state, Cobb douglas type production function was employed to assess the effects of seed, fertilizer, manure, human labour, irrigation, bullock labour and plant protection measures on pulses production. Result: The results from the study have shown that fertilizer and plant protection measures were positively significant while the variable corresponding to irrigation water was negatively significantly affecting the gram production. The variables such as seed and irrigation water were found positive and significant, while plant protection measures had significant negative effect on black gram production. Only two variables namely, fertilizer and irrigation water were found positively significant out of estimating production function of green gram.

On Amalgam Toxicity

1990 ◽  
Vol 6 (3) ◽  
pp. 363-368 ◽  
Author(s):  
Per-Olof Glantz ◽  
Ivar A. Mjör
Keyword(s):  
Adverse Effect ◽  
Toxic Substance ◽  
High Dose ◽  
Relative Term ◽  
Long Period ◽  
Dose Dependent

Toxicity implies an adverse effect. It may be caused by an overdose of any substance or combination of substances, either by an initial high dose or by the accumulation of a toxic substance over a long period of time. Thus, toxicity is dose dependent. It is also a relative term in that therisk involved must be evaluated and the available alternatives assessed.

Effects of potassium azide on soil microbial populations and soil enzymatic activities

1975 ◽  
Vol 21 (4) ◽  
pp. 565-570 ◽  
Author(s):  
W. D. Kelley ◽  
R. Rodriguez-Kabana
Keyword(s):  
Soil Enzyme ◽  
Soil Microflora ◽  
Microbial Populations ◽  
Bacterial Populations ◽  
Soil Microbial ◽  
Fungal Populations ◽  
Potassium Azide ◽  
Time Changes ◽  
Bacteria And Fungi ◽  
Microbial Numbers

Preplant applications of potassium azide (KN3) to pine nursery beds were evaluated for effect on the soil microflora and on soil enzyme activity where either plastic-sealing or water-sealing techniques were used. Two weeks after incorporation of azide (0–224 kg/ha), soil samplings revealed reduced populations of bacteria and fungi and a corresponding decline in invertase and amylase activities. These effects were proportionate to the amount of azide used and were more pronounced in plastic-sealed plots. Phosphatase activity was little affected. Five weeks after azide application, bacterial populations were higher in treated plots than in controls. Greater numbers of bacteria were recorded from plastic-sealed plots and highest populations coincided with plots receiving the highest rates of azide, regardless of the sealing technique. Fungal populations at this sampling were generally less in treated plots than in the controls, but were higher under plastic seal. At this time, changes in invertase and amylase activities did not correspond to increased microbial numbers. Sixteen weeks after applications of KN3, bacterial populations in treated plots did not differ significantly from controls, but remained higher in plastic-sealed than water-sealed plots. Fungal populations under plastic seal had changed little and remained significantly lower in treated water-sealed plots than in controls. The earlier recorded reduction in invertase and amylase activities was still evident at the final sampling.

scholarly journals Corticosteroid induced avascular necrosis and COVID-19: The drug dilemma

2021 ◽  
Vol 11 (3) ◽  
pp. 1049-1052
Author(s):  
Indrajit Banerjee ◽  
Jared Robinson ◽  
Brijesh Sathian
Keyword(s):  
Adverse Effect ◽  
Femoral Head ◽  
Avascular Necrosis ◽  
Steroid Therapy ◽  
Case Reports ◽  
Weight Bearing ◽  
Inflammatory Cells ◽  
High Dose ◽  
Intraosseous Pressure ◽  
Femoral Head Osteonecrosis

The severe and life-threatening nature of the COVID-19 infection, the ARDS (acute respiratory distress syndrome) as well as the cytokine storm induced by the infection, commands lifesaving high doses of steroid therapy. As in all pharmacological therapies adverse effects are present. One such adverse effect which is being reported is corticosteroid induced avascular necrosis of the femoral head/ osteonecrosis of the femoral head. It must be noted that AVN principally affects the femoral head and most commonly the anterolateral aspect thereof as it is the crux of weight bearing.  Corticosteroids induce fat mobilization and this thus innately enhances the likelihood of fat emboli developing from the liver to occlude minor blood vessels in the femur, this thereby compromises the microvascular environment. Superadded to this the steroid therapy disrupts calcium metabolism and homeostasis which induces hypertrophy in the intramedullary fat cells, Gaucher cells and inflammatory cells; whilst increasing the activity of osteoclasts, thus increasing bone resorption and decreasing calcium uptake and deposition; ultimately leading to an insufficiency in the trabecular and cortical bone. This insufficiency thus equates to an increased intraosseous pressure which impedes intramedullary circulation and results in avascular necrosis.  It is evident that avascular necrosis is directly caused by high dose steroid therapy, however the case reports have very clearly indicated that the rapid onset of AVN post recovery from the COVID-19 infection cannot be solely attributed to steroid therapy and that another benefactor induced by the COVID-19 infection is at play. It is thus vital for treating physicians to take cognisance of this adverse effect post recovery and therefore should ensure that prophylactic bisphosphonate therapy is initiated timeously and congruently.

scholarly journals Influence of Microbiologically Enriched Mineral Fertilizers on Selected Groups of Microorganisms in the Rhizosphere of Strawberry Plants

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Lidia Sas-Paszt ◽  
Urszula Smolińska ◽  
Beata Kowalska ◽  
Magdalena Szczech ◽  
Anna Lisek ◽  
...  
Keyword(s):  
Adverse Effect ◽  
Bacillus Amyloliquefaciens ◽  
Soil Microorganisms ◽  
Paenibacillus Polymyxa ◽  
Mineral Fertilizers ◽  
Bacterial Strains ◽  
Beneficial Effects ◽  
Purpureocillium Lilacinum ◽  
Bacteria And Fungi ◽  
Positive Effect

Abstract In recent years, the use of bio-fertilizers enriched with specially selected microorganisms has been used more and more often. The beneficial effects of bio-fertilizers enriched with consortia of microorganisms on strawberry plants have been reported previously. The purpose of the research was to determine the effect of bio-fertilizers containing selected fungal and bacterial strains on the microorganisms living in the rhizosphere of strawberry plants. In the experiments described in this paper, synthetic mineral fertilizers were enriched with selected microorganisms. The fertilizer urea was enriched with the fungi Aspergillus niger and Purpureocillium lilacinum, while the fertilizers Polifoska 6 and Super Fos Dar 40 with strains of the bacteria Bacillus sp., Bacillus amyloliquefaciens, and Paenibacillus polymyxa. Bacteria and fungi belonging to these species can exert a positive effect on the growth of many plants. The results obtained in this study showed that the application of fertilizers enriched with microorganisms had different effects on the analyzed populations of soil microorganisms in the rhizosphere of strawberry plants. There were evidences of both, an adverse effect of the applied fertilizer and/or microorganisms, but more often, the beneficial effect was found on the abundance of the microorganisms in the rhizosphere of the strawberry. The most effective for the population of Pseudomonas bacteria was application of urea and fungi and Polifoska and bacteria. The highest number of phosphorus utilizing bacteria B was scored in the treatments containing NPK, NPK + fungi and urea 60% + fungi. The application of NPK + fungi and urea 100% + fungi as well as Super Fos Dar with bacteria was most beneficial for population of actinomycetes.

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