scholarly journals Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice

2014 ◽  
Vol 6 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Suzanah Abdul Rahman ◽  
Norul Athirah Mohamed Anwar ◽  
Shaik Sadak Basha ◽  
Saheera Kamarzaman
Keyword(s):  
Intraperitoneal Injection ◽  
Sperm Count ◽  
Reproductive Parameters ◽  
Group I ◽  
Testicular Weight ◽  
Significant Difference ◽  
Immobilisation Stress ◽  
Level Of Significance ◽  
Induced Changes ◽  
The Impact

The aim of the current study was to investigate changes in the reproductive parameters during stress and the impact of thymoquinone during the period. The effects of stress were measured through immobilisation stress on mice. Group I was administered normal saline daily via intraperitoneal injection while Groups II and III were subjected to 2 and 6 hours of immobilisation stress respectively. Groups IV and V were subjected to stress for 2 and 6 hours respectively followed by intraperitoneal injection of 10 mg/kg thymoquinone which was continued on alternate days. The level of significance was set at p<0.05 and statistical analysis showed significant difference in testicular weight of mice in groups II and III compared to the controls but no significant difference was obtained for sperm count between all groups. Sperm motility, however, was significantly different among the groups under stress for 2 and 6 hours and that of 6 hours with the treatment of thymoquinone when compared to the controls. The histology of the testes also indicated a few alterations in comparison to the controls in the germinal epithelium and spermatogenic pattern in groups III and V.

Impact of supplementing commercial rabbit pellets with fresh Moringa oleifera leaves on semen characteristics in rabbit bucks under tropical climate in Trinidad

2021 ◽  
Author(s):  
Krishna Mohan Kumar
Keyword(s):  
Sperm Motility ◽  
Moringa Oleifera ◽  
Sperm Count ◽  
Control Group ◽  
Computer Assisted ◽  
Group Iii ◽  
Group I ◽  
Significant Difference ◽  
Moringa Oleifera Leaves ◽  
The Impact

Objective This study aimed to evaluate the impact of the dietary supplement of Moringa oleifera leaves (MOL) on semen quality and characteristics in rabbits. Methods Eighteen (n=18) breeding bucks of New Zealand white, of similar age group, were used for the study. Three feeding regimes, (i) 100% commercial rabbit pellets (CRP)-Group I (ii) 90% CRP + 10% fresh MOL on a dry matter (DM) basis – Group II and (iii) 80% CRP + 20% fresh MOL on a DM basis – Group III, were adopted and the trial continued for 21 days. After adaptation to the diet, semen was collected from each buck and subjected to evaluation using a computer-assisted semen analyser. Results In Group III, the sperm count, normal sperm morphology, and sperm motility increased (52.0%) in comparison with the control (Group I; 50.1%). The inclusion of 20% Moringa oliefera in the diet (Group III) caused a significant increase (P<0.05) in semen concentration (Control =136.2 M/mL; Group III=297.2 M/mL). There was no significant difference (P>0.05) in sperm motility and semen volume among the groups. Conclusion The results suggest that supplementing commercial rabbit pellets with 20% fresh Moringa oliefera leaves on a DM basis can improve the quality and characteristics of semen in breeding bucks.

scholarly journals Impact of hemodialysis on the wellbeing of chronic kidney diseases patients: a pre-post analysis

2020 ◽  
Vol 27 (1) ◽  
Author(s):  
Um-e-Kalsoom ◽  
Sabiha Khan ◽  
Israr Ahmad
Keyword(s):  
Quality Of Life ◽  
Social Support ◽  
Perceived Social Support ◽  
Kidney Diseases ◽  
Chronic Kidney Diseases ◽  
Group I ◽  
Significant Difference ◽  
Group Ii ◽  
The Impact

Abstract Background Hemodialysis may have serious psychological impact upon patients suffering from chronic kidney diseases. The aim of the present study is to investigate the impact of hemodialysis on the wellbeing of individuals with chronic kidney diseases (CKD). Result A sample consists of (N = 100) CKD patients referred from neurology ward of Leady Reading Hospital Peshawar. Data was collected from both male (50%) and female (50%) in 2017. Participants were divided into two groups on the basis of pre-set criteria. In group I, individuals with 4–5 stage of CKD referred first time for dialysis treatment were recruited. Group II comprised of CKD patients with 1–3 stage. Demographic data sheet, Pakistan Anxiety and Depression, WHO Quality of Life scale, and Perceived Social support scale (PSS) were used to test the hypotheses. Paired sample t test was use to see the difference between pre- and post-analysis of depression, anxiety, QOL, and PSS in group I (experimental group). Results suggests significant difference on depression (p > .001), anxiety (p > .001), and QOL (p > .001), while no significant difference was reported on perceived social support (p <.673). Findings also indicate no significant difference between group I and group II on QOL depression, anxiety, and PSS. Conclusion The findings concluded that patients under hemodialysis treatment suffered from depression, anxiety, and poor quality of life.

scholarly journals Uncertainty of Measurement of Bulk and Shaken Density of Pulgran and Salmag

2020 ◽  
Vol 24 (3) ◽  
pp. 73-81
Author(s):  
Janusz Nowak ◽  
Wojciech Przystupa ◽  
Anna Krawczuk
Keyword(s):  
Statistical Analysis ◽  
Nitrogen Fertilizer ◽  
Central Office ◽  
Average Density ◽  
Test Results ◽  
Uncertainty Of Measurement ◽  
Error Sources ◽  
Significant Difference ◽  
Level Of Significance ◽  
The Impact

AbstractThe article presents results of research on the bulk and shaken density of two commercial fertilizers: Pulgran urea and universal nitrogen fertilizer Salmag. A statistical analysis of the obtained results of average density at the assumed level of significance proved a significant difference between shaken and bulk density investigated with the use of Engelsmann apparatus and shaken density tested with a laboratory shaker for both investigated fertilizers. The obtained test results and uncertainty of the measured values served for calculation of uncertainty of the standard complex bulk and shaken density determined in case of many uncertainties. Further, an analysis of the impact of error sources on the value of complex uncertainty was conducted. The final results of the measurement were presented according to the convention of the Central Office of Measures.

scholarly journals Comparative Evaluation of Neem Mouthwash on Plaque and Gingivitis: A Double-blind Crossover Study

2017 ◽  
Vol 18 (7) ◽  
pp. 567-571 ◽  
Author(s):  
RS Dhanya ◽  
VJ Adarsh ◽  
Md Jalaluddin ◽  
UB Rajasekaran ◽  
CB Sudeep
Keyword(s):  
Crossover Study ◽  
Comparative Evaluation ◽  
Second Phase ◽  
Slight Reduction ◽  
Double Blind ◽  
Group I ◽  
Significant Difference ◽  
The Impact ◽  
Blind Crossover Study ◽  
Double Blind Crossover Study

ABSTRACT Aim The present study aimed at evaluating the impact of neemcontaining mouthwash on plaque and gingivitis. Materials and methods This randomized, double-blinded, crossover clinical trial included 40 participants aged 18 to 35 years with washout period of 1 week between the crossover phases. A total of 20 participants, each randomly allocated into groups I and II, wherein in the first phase, group I was provided with 0.2% chlorhexidine gluconate and group II with 2% neem mouthwash. After the scores were recorded, 1-week time period was given to the participants to carry over the effects of the mouthwashes and then the second phase of the test was performed. The participants were instructed to use the other mouthwash through the second test phase. Results There was a slight reduction of plaque level in the first phase as well as in the second phase. When comparison was made between the groups, no statistically significant difference was seen. Both the groups showed reduction in the gingival index (GI) scores in the first phase, and there was a statistically significant difference in both groups at baseline and after intervention (0.005 and 0.01 respectively). In the second phase, GI scores were reduced in both groups, but there was a statistically significant difference between the groups only at baseline scores (0.01). Conclusion In the present study, it has been concluded that neem mouthwash can be used as an alternative to chlorhexidine mouthwash based on the reduced scores in both the groups. Clinical significance Using neem mouthwash in maintaining oral hygiene might have a better impact in prevention as well as pervasiveness of oral diseases as it is cost-effective and easily available. How to cite this article Jalaluddin M, Rajasekaran UB, Paul S, Dhanya RS, Sudeep CB, Adarsh VJ. Comparative Evaluation of Neem Mouthwash on Plaque and Gingivitis: A Double-blind Crossover Study. J Contemp Dent Pract 2017;18(7):567-571.

scholarly journals The outcome of implementing antimicrobial stewardship program for hospitalized children

2018 ◽  
Vol 5 (9) ◽  
pp. 3737
Author(s):  
Ahmed A. El-Nawawy ◽  
Reham M. Wagdy ◽  
Ahmed Kh. Abou Ahmed ◽  
Marwa A. Moustafa
Keyword(s):  
Antimicrobial Stewardship ◽  
Antibiotic Use ◽  
Antimicrobial Use ◽  
Hospitalized Children ◽  
Antimicrobial Stewardship Program ◽  
Stewardship Program ◽  
Group I ◽  
Significant Difference ◽  
Patient’S Outcome ◽  
The Impact

Background: An effective approach to improve antimicrobial use for hospitalized patients is an antimicrobial stewardship program (ASP). The present study aimed to implement ASP for inpatient children based on prospective-audit-with-feedback intervention in order to evaluate the impact on patient’s outcome, antimicrobial use, and the hospital cost.Methods: The study was conducted throughout 6 months over 275 children admitted with different infections at Main Children’s hospital in Alexandria included; group I (with ASP) and group II (standard antimicrobials as controls).Results: The study revealed that on patient’s admission, single antibiotic use was higher among the ASP group while double antimicrobial therapy was higher among the non-ASP with significant difference (p=0.001). Less percentage of patients who consumed vancomycin, meropenem amoxicillin-clavulanic and metronidazole was observed among ASP group with a significant difference of the last two drugs when compared to controls (p=<0.001, 0.011, respectively). The study reported the higher percent of improved ASP patient’s after 72 hours of admission with a significant difference to controls (73.2% versus 62.5%, p=0.038). Complications occurred more likely for the non-ASP group (odds ratio 7.374 with 95% CI 1.68-32.33). In general, there was a clear reduction of the patient antibiotic cost/day and overall cost per patient, however, it was not significant among the studied patients.Conclusions:  Our local ASP model provided a high quality of care for hospitalized children and effectively reduced the antimicrobial consumption.

scholarly journals Competency Improvement Needs of Farmers in Afforestation for Preventing and Controlling Soil Erosion in Kogi State, Nigeria

2020 ◽  
pp. 37-45
Author(s):  
Abu Mohammed ◽  
Ogbonnaya Elom ◽  
Ogechukwu Onah ◽  
Nnennaya Sinachi Monwuba
Keyword(s):  
Soil Erosion ◽  
Data Collection ◽  
Crop Production ◽  
Research Question ◽  
Sampling Technique ◽  
Agricultural Extension ◽  
Extension Agents ◽  
Significant Difference ◽  
Level Of Significance ◽  
The Impact

Farmers’ lack of awareness of agricultural activities that contribute to soil erosion and competencies needed to prevent or control the menace through afforestation contributed to unprecedented hardship, the farmers, stakeholders and individuals in Kogi state. The purpose of this study was to determine competency improvement needs farmers in pre-planting, planting and post-planting operations in afforestation and recommend for a way forward in containing the challenges. Three research question and three hypotheses guided the study. The study made use of survey research design; it was carried out in Kogi state. The population for the study was 1,244 made up of 834 registered crop farmers and 410 Agricultural Extension Agents. The sample of the study was 540. A random sampling technique (Balloting) was used to select 330 registered crop farmers out of 834 and 210 Agricultural Extension Agent out of 410 respectively. The instrument for data collection was a 49 items questionnaire titled: Competency Improvement Needs of farmers Questionnaire (CINFQ). The instrument was validated by three experts. Cronbach Alpha method was used to determine the internal consistency of the instrument and a reliability coefficient of 0.82was obtained. Five hundred and forty (540) copies of the questionnaire were administered to the respondents for data collection, but 534 copies were retrieved and analyzed. Weighted mean and Improvement Needed Index (INI) were used to answer the research questions while t-test statistics was used and test hypotheses of no significant difference at the probability of 0.05 level of significance at 532 degree of freedom. It was found out that farmers needed improvement in all the competencies in pre-planting, planting and post-planting operations for enhancing their skills in afforestation practices on their farms and that of their neighbours as a means of reducing the impact of soil erosion in the area of the study. It was recommended that the identified competencies should be used by the extension agents to re-train farmers on the practice of afforestation along with crop production and soil conservation to reduce soil erosion menace in the State.

scholarly journals Impact of Mouthwashes on Antibacterial Activity of Subjects with Fixed Orthodontic Appliances: A Randomized Clinical Trial

2017 ◽  
Vol 18 (12) ◽  
pp. 1112-1116
Author(s):  
A Nishad ◽  
NS Sreesan ◽  
Joseph Joy ◽  
Lakshmi Lakshmanan ◽  
Joyce Thomas ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Antibacterial Activity ◽  
Randomized Clinical Trial ◽  
Control Group ◽  
Orthodontic Appliances ◽  
Group I ◽  
Fixed Orthodontic Appliances ◽  
Significant Difference ◽  
The Impact ◽  
Experimental Group

ABSTRACT Aim The study aimed to assess the impact of mouthwashes on antibacterial activity of individuals with fixed orthodontic appliances. Materials and methods A total of 60 individuals were considered in the study. Sixty (20 each group) nonextraction class I individuals were randomly divided into experimental and control groups. Group I: Experimental group [chlorhexidine (CHX) mouthwash], group II: Experimental group (neem mouthwash), group III: Control group (distilled water). All the clinical examinations were done at baseline and 30th day respectively, after the start of orthodontic treatment. The mean differences between the different experimental groups were calculated using one-way analysis of variance (ANOVA) test. Results There was no statistical significance at baseline mean plaque index (PI), gingival index (GI) scores, and Streptococcus mutans (SM) colony count between groups. The PI and GI scores among CHX and neem mouthwash groups (p = 0.002, p = 0.032 respectively) were significantly reduced after intervention and also the SM colonies count was reduced in CHX and neem mouthwash groups and there was significant difference between the groups. Conclusion As both mouthwashes showed significant effectiveness on antibacterial activity in individuals with fixed orthodontic appliances, neem mouthwash can be used as an alternative to CHX. Clinical significance It is better to have a sound knowledge regarding the use of mouthwash in long term as fixed orthodontics are associated with accumulation of SM, enamel demineralization, and an increased number of carious lesions, predominantly in sites adjacent to bracket. How to cite this article Nishad A, Sreesan NS, Joy J, Lakshmanan L, Thomas J, Anjali VA. Impact of Mouthwashes on Antibacterial Activity of Subjects with Fixed Orthodontic Appliances: A Randomized Clinical Trial. J Contemp Dent Pract 2017;18(12):1112-1116.

scholarly journals An Experimental Investigation of the Impact of Electromagnetic Radiations Emitted from Mobile Phone on General Health, pH, Flow Rate and Electrolytes Concentrations of Saliva in Female Adults

2018 ◽  
Author(s):  
Etimad Alattar ◽  
Khitam Elwasife ◽  
Eqbal Radwan ◽  
Hadeer Abu Warda ◽  
Mohammed Abujami
Keyword(s):  
Mobile Phone ◽  
Mobile Phones ◽  
Flow Rate ◽  
General Health ◽  
Control Group ◽  
Inclusion Criteria ◽  
Group I ◽  
Significant Difference ◽  
The Impact ◽  
Electromagnetic Radiations

During the recent years, there has been a tremendous increase in use of mobile phones which resulted in an increase of the exposure to electromagnetic radiations in our life. Human saliva is considered as a potential source of biomarkers to monitor changes that occur under pathological conditions. The main objective of the current experiment was to determine the effect of mobile phone radiation on general health, electrolytes and salivary function among Islamic University students who use mobile phones. A questionnaire was designed and applied to 167 healthy and 36 deaf female students to select cases whose meeting the inclusion criteria. A total of 103 students who met the inclusion criteria were included to investigate the influence of mobile phone radiations on their general health. For assessment of salivary parameters, a total of 55 students were chosen and classified into three groups. Group I was the control group, which included 17 deaf students who did not use the mobile phone at all. Group II was healthy students who have mobile phone for less than 5 years. Group III was healthy students who have mobile phone for 5 years or more. Descriptive data that included mean, standard deviation, and percentages was calculated for each group. Multiple group comparisons were made by one-way analysis of variance (ANOVA) followed by Tukey test for pairwise comparisons. Categorical data were analyzed by Chi square (&chi;2) test. For all the tests, a P value of 0.05 or less was considered for statistical significance. The results showed that the participants who use mobile phone had several problems in their health including dry mouth, bad odor from mouth, drooling of saliva, as well as ear and eye pain. The majority of the participants who use mobile phone complained of headache, anxiety, insomnia and forgetfulness as compared to deaf participants. Also, the study showed that there was no significant difference between salivary pH in all tested groups. Regarding to salivary flow rate, the differences were no significant in all tested groups. In addition, this study has also shown that there was significant difference between the salivary Na+ and K+ levels of the three groups. Salivary level of Na+ and K+ were significantly lower in mobile phone users when compared to non users of mobile phone.

scholarly journals The impact of Rumex vesicarius seed water extracts on mice fertility

2021 ◽  
Author(s):  
Ahmad Rashed Alhimaidi ◽  
Aiman Abdullah. Ammari ◽  
Mohammad Khair Okla ◽  
Muath Qasem Algadi ◽  
Ramzi Ahmed Amran ◽  
...  
Keyword(s):  
Antioxidant Properties ◽  
Feeding Tube ◽  
Oral Feeding ◽  
The Other ◽  
Female Group ◽  
Mating Group ◽  
Group I ◽  
Significant Difference ◽  
The Impact ◽  
Seed Extracts

AbstractRumex vesicarius (RV) is an edible wild annual plant, and it is reported that it contains a good source of minerals, protein, and ascorbic acid. Several studies have indicated the anti-liver damage, anticancer, antimicrobial, and antioxidant properties of the RV plant. There are currently no reports regarding the effect of RV on fertility. Therefore, this study focuses on the impact of RV water seed extracts on mice fertility. RV plants were collected, and water seed extracts were prepared; 50 mg/kg body weight (BW) of this was then injected into the mice (male and female) using an oral feeding tube 5 days before mating (group I) or during caging of the females with the males for 1 week to detect their fertility rate. In the different female groups, no significant difference between their BW and their newborn’s BW in the treated and control groups was found. Female fertility, pregnancy, and offspring rates showed some variation within each female group and between the different female groups. In comparing the fertility and offspring rate between the different groups, there was a significant difference (P < 0.05) between groups I and III females and between groups I and IV females, while the other groups showed no significant differences. In contrast, the other groups showed no significant differences. Regarding the impact of the water seed extract on males, the BW was approximately the same in control and treated males.

scholarly journals Is standard radical surgery necessary for elderly patients with early-stage epithelial ovarian carcinoma? ~Propensity score matched analysis~

2019 ◽  
Vol 50 (4) ◽  
pp. 411-418
Author(s):  
Hiroaki Kajiyama ◽  
Masato Yoshihara ◽  
Satoshi Tamauchi ◽  
Nobuhisa Yoshikawa ◽  
Kaoru Niimi ◽  
...  
Keyword(s):  
Propensity Score ◽  
Elderly Patients ◽  
Radical Surgery ◽  
Early Stage ◽  
Group I ◽  
Significant Difference ◽  
Limited Surgery ◽  
Matching Technique ◽  
Clinicopathologic Factors ◽  
The Impact

Abstract Objective The impact of ‘standard full-staged radical surgery (SRS)’ on overall survival (OS) in elderly patients with early-stage epithelial ovarian cancer (EOC) remains unclear. In the current study, we investigated the impact of SRS on OS in elderly patients with early-stage EOC in a multicentric analysis using a propensity score (PS)-matching technique. Methods Between 1986 and 2017, 3227 patients with EOC were registered and accumulated by the Tokai Ovarian Tumor Study Group, consisting of 14 collaborating institutions, after a central pathological review. Among them, 204 elderly patients aged older than or equal to 65 years who had a stage I EOC were analyzed, including 72 patients who had received SRS (Group I) and 132 who had undergone non-SRS limited surgery (Group II). Oncologic outcomes were compared between the two groups using a PS-matching technique to adjust for various clinicopathologic risk factors. Results The median follow-up duration of all surviving patients was 55.9 months. Consequently, 54 patients (26.5%) developed recurrence. In addition, 33 patients (16.2%) died of the disease. In the original cohort, the 5-year OS rates of Groups I and II were 95.8 and 82.3%, respectively. We identified a marginally significant difference between the two groups (Log-rank: P = 0.086). In the PS-matched cohort after adjustment for multiple clinicopathologic factors, there was no significant difference in OS between the two groups [OS (Group I vs. II), HR: 0.766 (95% CI: 0.271–2.165), P = 0.615]. Conclusions After adjustment for clinicopathologic factors, non-SRS limited surgery may not worsen the oncologic outcome in elderly women with early-stage EOC. A large-scale clinical study is necessary to validate the findings.

Sign in / Sign up

Export Citation Format

Share Document