scholarly journals Extragenital noninfectious pathology in the maternal mortality structure in Moscow

2021 ◽  
Vol 10 (2) ◽  
pp. 21-31
Author(s):  
L.M. Mikhaleva ◽  
◽  
A.G. Konoplyannikov ◽  
Y.Y. Kudryavtseva ◽  
A.S. Olenev ◽  
...  
Keyword(s):  
Arteriovenous Malformation ◽  
Maternal Mortality ◽  
Pregnant Women ◽  
Cause Of Death ◽  
Single Case ◽  
Multidisciplinary Treatment ◽  
Circulatory System ◽  
Gastrointestinal Diseases ◽  
Malignant Neoplasms ◽  
Circulatory System Diseases

Introduction. Diseases directly related to pregnancy are still leading the maternеal mortality structure, al-though in many countries there is an increase in the number of deaths from extragenital pathology among pregnant women. A significant number of lethal cases in this group are associated with environmental factors, lifestyle, and the overall increase in somatic diseases. The aim of the study was to determine the main causes of maternal mortality and investigate the role of extragenital pathology based on autopsy data. Materials and methods. The study included 29 autopsy observations. We studied medical records, autopsy protocols of deceased pregnant women, women in labor, and puerperant women. Each cause of death was classified according to ICD-10. A clinical and morphological study was also carried out using additional histochemical and immunohistochemical staining methods. Results. The data from pathological studies show that in Moscow, extragenital pathology accounts for up to 40% of maternal deaths. The leading cause of death is circulatory system diseases, including an arteriovenous malformation; a myocardial infarction; a congenital heart disease (patent foramen ovale); cerebral, aortic, and splenic artery aneurysms. The second most common one is other specified diseases and conditions com-plicating pregnancy. This group of diseases included malignant neoplasms. Less common causes of death are gastrointestinal diseases, other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism that complicate pregnancy, and also respiratory diseases. A single case is associated with a generalized viral infection. Conclusion. Extragenital pathology remains an important obstetric problem, and the management of pregnant women with systemic diseases requires a multidisciplinary treatment approach. Keywords: maternal mortality, extragenital pathology, arteriovenous malformation, cerebral aneurysm, antiphospholipid syndrome

Mortality Profile Related to Systemic Lupus Erythematosus: A Multiple Cause-of-death Analysis

2012 ◽  
Vol 39 (3) ◽  
pp. 496-503 ◽  
Author(s):  
DEBORAH C.C. SOUZA ◽  
AUGUSTO H. SANTO ◽  
EMILIA I. SATO
Keyword(s):  
Renal Failure ◽  
Cause Of Death ◽  
Lupus Erythematosus ◽  
Digestive System ◽  
Causes Of Death ◽  
Circulatory System ◽  
Systemic Lupus ◽  
Circulatory System Diseases ◽  
Underlying Causes ◽  
Digestive System Diseases

Objective.To analyze the mortality profile related to systemic lupus erythematosus (SLE) in the state of São Paulo, Brazil.Methods.For the 1985–2007 period, we analyzed all death certificates (n = 4815) on which SLE was listed as an underlying (n = 3133) or non-underlying (n = 1682) cause of death. We evaluated sex, age, and the causes of death, comparing the first and last 5 years of the period, as well as determining the observed/expected death ratio (O/E ratio).Results.For SLE as an underlying cause, the mean age at death was 35.77 years (SD 15.12) and the main non-underlying causes of death were renal failure, circulatory system diseases, pneumonia, and septicemia. Over the period, the proportional mention of infectious causes and circulatory system diseases increased, whereas renal diseases decreased. For SLE as a non-underlying cause of death, the most common underlying causes of death were circulatory, respiratory, genitourinary, and digestive system diseases, and certain infections. The overall death O/E ratio was > 1 for renal failure, tuberculosis, septicemia, pneumonia, and digestive system diseases, as well as for circulatory system diseases at < 50 years of age, particularly acute myocardial infarct.Conclusion.Unlike in developed countries, renal failure and infectious diseases are still the most frequent causes of death. The increase in SLE deaths associated with infection, especially pneumonia and septicemia, is worrisome. The judicious use of immunosuppressive therapy together with vigorous treatment of cardiovascular comorbidities is crucial to the successful management of SLE and to improving survival of patients with SLE.

scholarly journals Changing the landscape of stroke in Egypt

2021 ◽  
Author(s):  
Hany Aref ◽  
Magd Zakaria ◽  
Hossam Shokri ◽  
Tamer Roushdy ◽  
Ahmed El Basiouny ◽  
...  
Keyword(s):  
Middle East ◽  
Cause Of Death ◽  
Prevalence Rate ◽  
Circulatory System ◽  
Gastrointestinal Diseases ◽  
Middle Income Country ◽  
Middle Income ◽  
National Statistics ◽  
The Past ◽  
Crude Prevalence

Egypt, a low–middle-income country, is the most populated nation in the Middle East. In Egypt, the overall crude prevalence rate of stroke is high (963/100,000 inhabitants), and the incidence of stroke annually is approximately 150 000 to 210 000. The official national statistics indicate that diseases of the circulatory system, including stroke, are the primary cause of death in Egypt, where stroke accounts for 6.4% of all deaths and ranks third after cardiovascular and gastrointestinal diseases. Although the number of deaths attributed to stroke have declined in many countries, in Egypt, it was relatively unchanged in the past 10 years.

scholarly journals Characteristics of patients with psoriatic arthritis treated with ustekinumab. Evidence from real-life clinical practice

2021 ◽  
pp. 274-283
Author(s):  
Yu. L. Korsakova ◽  
E. Yu. Loginova ◽  
E. E. Gubar ◽  
T. V. Korotaeva
Keyword(s):  
Psoriatic Arthritis ◽  
Clinical Laboratory ◽  
Real Life ◽  
Circulatory System ◽  
Latent Tuberculosis ◽  
Endocrine System ◽  
Gastrointestinal Diseases ◽  
Good Tolerability ◽  
Viral Hepatitis C ◽  
Circulatory System Diseases

Introduction. Psoriatic arthritis (PsA) is a chronic immunoinflammatory disease characterised by involvement of the skin, nail plates, joints, spine and entheses in the inflammatory process. The IL-12/IL-23 inhibitor ustekinumab (UST) is increasingly being used in psoriasis (Ps) and PsA.Aim of the study. To analyze patients with PsA who were under inpatient treatment in the V.A. Nasonova Scientific Research Institute of Rheumatology and Radiology and who were prescribed UST during the period from 2018 to 2020.Material and methods. UST was administered to 17 patients with PsA (9 women and 8 men), mean age was 46.4 ± 11.3 years. Duration of PsA course was 11 ± 10.5 years. Patients underwent clinical, laboratory and instrumental examination, BSA and PASI, DAPSA and BASDAI indices were determined.Results. Patients predominantly had widespread Ps (BSA 18.2 ± 15.9%). Erosive arthritis was present in 94.1% of patients, and sacroiliitis was detected in 100% of patients. PsA activity was high (DAPSA = 44.9 ± 20.9, BASDAI = 6.2 ± 1.5).94% of patients had two or more comorbidities. Circulatory system diseases were observed in 82.4% of patients, liver diseases in 29.5%, gastrointestinal diseases in 47%, endocrine system diseases in 17.6%, viral hepatitis C in 23.5%, latent tuberculosis infection in 17.6%, and joint surgery was performed in 11.2% of patients. The clinical example presented in the article demonstrates good tolerability of UST in a patient with PsA with a number of comorbidities and the possibility to increase the dose of UST from 45 to 90 mg in case of ineffective therapy.Conclusions. The safety profile of UST is good, and it can be administered to patients with cardiovascular diseases, obesity, various infections, including latent tuberculosis, etc. 

scholarly journals Sudden death from diseases of the system of the blood circulation in workers of enterprises of various industries of the economy of the Republic of Bashkortostan

2021 ◽  
Vol 100 (4) ◽  
pp. 327-332
Author(s):  
Lilya K. Karimova ◽  
Zulfiya F. Gimaeva ◽  
Tatyana N. Astrelina ◽  
Nadezhda A. Muldasheva ◽  
Akhat B. Bakirov ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Sudden Death ◽  
Cause Of Death ◽  
Working Conditions ◽  
Circulatory System ◽  
Republic Of Bashkortostan ◽  
Circulatory System Diseases ◽  
The Republic ◽  
Medical Examinations

Introduction. In Russia and abroad, there has been a clear trend towards an increase in cases of sudden death in the workplace from circulatory system diseases over the past decade. Materials and methods. During the study, the databases of the State Labor Inspectorate in the Republic of Bashkortostan for 2014-2018 were studied, including accident investigation reports, information on a special assessment of working conditions, medical examinations, forensic medical examinations, and other materials. Results. The leading cause of sudden death in the workplace in more than 90% of cases were circulatory system diseases (CSD). The maximum number of cases of sudden death from CSD was recorded in the age group of 56-60 years. Working condit ions represented the overwhelming majority of the deceased - 82.8%. In 13.7% of cases, they were drivers of transport. The vast majority of deaths occurred in the morning (from 6 to 12) and daytime (from 12 to 18). The working conditions of workers from deceased CSD in most cases (59.8%) corresponded to the permissible class (class 2); under harmful conditions (subclass 3.1-3.3), 24.9% worked. Most often, some form of acute coronary heart disease (CHD) was mentioned as the immediate cause of death (64.0%). Among acute forms of coronary heart disease in medical documents, in more than 50% of cases, code I 24.8 “Other forms of acute coronary heart disease” was established. “Acute myocardial infarction” was verified in 11.1% of patients and was the leading cause of death in men. In the group “Cerebrovascular Diseases,” “Intracerebral hemorrhage” was most often diagnosed. Conclusion. The obtained results substantiate the need to develop measures to prevent sudden death in the workplace, aimed primarily at preventing the development, progression, and early diagnosis of diseases of the circulatory system.

scholarly journals The adult mortality profile by cause of death in 10 Latin American countries (2000–2016)

2020 ◽  
Vol 44 ◽  
pp. 1 ◽  
Author(s):  
Júlia Almeida Calazans ◽  
Bernardo Lanza Queiroz
Keyword(s):  
Cause Of Death ◽  
Latin American ◽  
Causes Of Death ◽  
Circulatory System ◽  
Adult Mortality ◽  
World Health ◽  
Epidemiological Transition ◽  
Circulatory System Diseases ◽  
Health Organization ◽  
Latin American Countries

Objective. To investigate the adult mortality profile from eight causes of death in 10 Latin American countries (Argentina, Brazil, Chile, Colombia, Costa Rica, Ecuador, Mexico, Paraguay, Peru, and Uruguay) from 2000 to 2016. Methods. The cause of death effect in adult mortality was calculated as the hypothetical gain in the average number of years lived in adulthood (15 to 60 years old), in a cause-deleted life table. Mortality information by cause, sex, and age group came from the World Health Organization. Results. Although the adult mortality levels are very different among the 10 countries, the pattern of mortality by cause of death is very similar. All the countries are in the intermediate stages of the epidemiological transition, with chronic degenerative diseases being predominant. Among males, circulatory system diseases and external causes are the most important causes of death in terms of the average number of years lived in adulthood. Among females, the leading causes are circulatory system diseases and neoplasms. Conclusions. Some studies have pointed out that Latin America exhibits severe difficulties in moving through some epidemiological transition phases, given the continuing high mortality from chronic diseases and violent deaths. However, between 2000 and 2016, there was a convergence among the 10 analyzed countries around the theoretical limit in the average number of years lived in adulthood. Countries that include Brazil, Colombia, Ecuador, Mexico, Paraguay, and Peru are still further away from this limit, but they have an enormous potential to increase the number of years lived in adulthood in the future.

Aged Population Disability Processes Analysis In The Republic Of Kazakhstan

2013 ◽  
Vol 5 ◽  
Author(s):  
Akmaral Abikulova ◽  
Kazbek Tulebaev ◽  
Aikan Akanov ◽  
Botagoz Turdalieva ◽  
Sundetgali Kalmahanov ◽  
...  
Keyword(s):  
Causal Structure ◽  
Circulatory System ◽  
Malignant Neoplasms ◽  
Urogenital System ◽  
Metabolic Disturbances ◽  
Endocrine Diseases ◽  
Aged Population ◽  
Circulatory System Diseases ◽  
Disability Status ◽  
Blood Circulatory System

Background:We have analyzed the aged population disability processes to establish specifics and regularities of the causal structure of disability among the working and non-working aged population.Methods:In total, 1208 examination reports of the Medical & SocialExpert Commission have been subjected to excerption in Almaty.  Results:Persons having the second disability status prevail in the working aged contingent – 4,4%, which is much higher than the ratios for the first and second disability statuses (0,4%and 0,6%, respectively). Among the non-working population, persons having the second disability status largely prevail too - 8,1% (3,1%and 1,1%, respectively). The casual structure of disability among the non-working disabled persons includes as follows: blood circulatory system diseases (40%), malignant neoplasms (27,2%), and diseases of the eye and its appendages (10,2%). They are followed by endocrine diseases, nutritional and metabolic disturbances (7,6%), bodily injuries (3%),and urogenital system diseases with musculoskeletal system ones - 2,3% each.The data collection for the working aged populationcontingent has found out blood circulatory system diseases (47%) and malignant neoplasms (34,4%). Alongside with that, the distinctive feature among the said aged populationcohort is a substantial predominance of bodily injuries (7,4%), endocrine diseases, nutritional and metabolic disturbances (2,3%), and only 1,4% is accounted for diseases of the eye and its appendages. 

scholarly journals Sustainability in transformation of maternal mortality by interaction based approach in Dairi, Indonesia

2021 ◽  
Author(s):  
Henry Manik ◽  
Rika Subarniati Triyoga ◽  
M. Fidel G. Siregar ◽  
R. Kintoko Rochadi ◽  
Sandeep Poddar
Keyword(s):  
Mixed Methods ◽  
Mortality Rate ◽  
Maternal Mortality ◽  
Pregnant Women ◽  
Cause Of Death ◽  
Health Workers ◽  
Contributing Factors ◽  
Maternal Mortality Rate ◽  
Build Systems ◽  
Health And Mortality

Introduction: Health and mortality problems are closely related to the maternal mortality rate (MMR). Efforts to reduce MMR have been carried out by many countries, including the Indonesian government. Materials and Methods: This research was conducted using two approaches, namely quantitative and qualitative or mixed methods and 149 respondents and 26 informants, to reduce MMR in Dairi Regency. This study was also carried out to determine the dominant variable that affects mother's behavior in an effort to reduce MMR in accordance with the existing theory. Result: Mother's intention to contribute to the reduction of MMR in this study was influenced by the good factor directly or indirectly. This is indicated by the score p<0.005. The study also shows that it is very important for the health workers to be able to communicate well with individuals and communities. Conclusion: The present study will help to reduce maternal fatalities, and will help to build systems and processes that will allow control the behaviour of the pregnant women and determine the cause of death as well as its contributing factors.

scholarly journals Regional features of pregnant women's health

2021 ◽  
pp. 21-28
Author(s):  
Y.G. Antypkin ◽  
T.F. Tatarchuk ◽  
R.V. Marushko ◽  
O.O. Dudina
Keyword(s):  
Pregnant Women ◽  
Women’S Health ◽  
Women's Health ◽  
Objective Assessment ◽  
Circulatory System ◽  
Health Indicators ◽  
Genitourinary System ◽  
Regional Characteristics ◽  
Circulatory System Diseases ◽  
Integral Assessment

Purpose of the study: to determine the regional characteristics of the health indicators of pregnant women on the basis of integral assessment of extragenital pathology, complications and adverse consequences of pregnancy. Materials and methods. A comprehensive retrospective analysis of regional characteristics and dynamics of the main indicators of pregnant women’s health in Ukraine for the period 2010–2019 was carried out. According to the Center for Medical Statistics of Ukraine integral assessment (IA) of pregnant women’s health was carried out according to the generally accepted calculation method using integral indicators of the extragenital pathology frequency, pregnancy complications and its adverse consequences.Results. Health of pregnant women remains unsatisfactory with multidirectional trends in the frequency of individual pathologies in recent years. Simultaneously with a downward trend against the background of a high level of anemia and genitourinary system diseases (24.73 and 14.38 per 100 pregnant women in 2019, the rate of decline was 6.29% and 1.74%), gestosis, preeclampsia and eclampsia (6.57, 2.11 and 1.2%, 9.48%), not carrying a pregnancy, delivering a dead fetus (5.84, 0.43 and 15.92%, 9.3%), the incidence of circulatory system diseases and thyroid gland dysfunctions (7.61, 9.88, growth rate 18.7%, 2.33%) is increasing. Incidence of diabetes in pregnant women in Ukraine rapid increases in 10.4 times (0.17 per 100 pregnant women in 2010 and 0.77 in 2019). High regional differences in the frequency of different pathologies of pregnant women were revealed. The difference between the highest and lowest rates of circulatory system diseases in 2019 was 23.9 times, diabetes mellitus – 12.6 times, thyroid diseases – 5.4 times, genitourinary system diseases – 4.3 times, anemia in pregnant women – 3.4 times, and complications and adverse effects of pregnancy – 2.4–4.7 times. The analysis of the IA of the health status of pregnant women according in 2019 revealed that the level of health was higher than the average in Ukraine in Ivano-Frankivsk (65.5%), Zaporizhzhya (72.82%), Odesa (75.5%), Zakarpattia (76.5%), Lviv (81.1%), Sumy (81.3%), Luhansk (84.3%) and Ternopil (84.4%) regions, and low than the average level in Dnipropetrovsk (132.35%), Poltava (123.1%), Chernivtsi (118.0%), Chernihiv (111.7%) regions and Kyiv (117.1%). Conclusions. Developed toolkit for the IA of pregnant women’s health makes it possible to provide an objective assessment of pregnant women’s health in general and for individual components in the context of regions as a means of timely identification of problems that require intervention and effective management decisions to minimize risk factors that cause impaired health in pregnant women.

scholarly journals Assessment of medical and losses due to socially significant diseases in the East Kazakhstan Region

2020 ◽  
pp. 543-549
Keyword(s):  
Circulatory System ◽  
Economic Loss ◽  
World Health ◽  
Malignant Neoplasms ◽  
Years Of Life Lost ◽  
Study Region ◽  
Active Population ◽  
Circulatory System Diseases ◽  
East Kazakhstan ◽  
Health Organization

AIMS. The aim of the research was assessment of the medical and social losses due to socially significant diseases (malignant neoplasms and diseases of the circulatory system) in population living in the ecologically unfavorableregion of Kazakhstan (East Kazakhstan Region (EKR)). MATERIALS AND METHODS.The materials for the research were provided by the Department of Statistics, the Republican Center of Electronic Health Care and the Regional Oncology Center for 5 years depth (2011-2015 yy.). Statistical data of the entire population of the region was analyzed. Years of Life Lost (YLL), YLL due to death integral indicators were calculated according to the standardized methodology recommended by the World Health Organization (WHO). RESULTS AND CONCLUSION. Significant premature loss of years due to socially significant diseases in the study region was observed in the research group of 45-69 years with a gender prevalence in male. The fraction of direct economic loss as a result ofhealth losses due to circulatory system diseases and malignant neoplasms averaged about 5% of the Gross Domestic Product (GDP). The medical and social losses of years depend on a number of social and economic factorsin the region (environmental pollution, population income, centralized water supply and the fraction of economically active population).

Quantifying Pregnant Women’s Knowledge of Educational Components of Antenatal Care in Lesotho

2019 ◽  
Vol 21 (1) ◽  
Author(s):  
Tabeta Seeiso ◽  
Mamutle M. Todd-Maja
Keyword(s):  
Antenatal Care ◽  
Maternal Mortality ◽  
Pregnant Women ◽  
Rural Areas ◽  
Geographic Location ◽  
Sub Saharan Africa ◽  
World Health ◽  
Cross Sectional ◽  
Danger Signs ◽  
In Pregnancy

Antenatal care (ANC) literacy is particularly important for pregnant women who need to make appropriate decisions for care during their pregnancy and childbirth. The link between inadequate health literacy on the educational components of ANC and maternal mortality in sub-Saharan Africa (SSA) is undisputable. Yet, little is known about the ANC literacy of pregnant women in SSA, with most studies inadequately assessing the four critical components of ANC literacy recommended by the World Health Organization, namely danger signs in pregnancy; true signs of labour; nutrition; and preparedness for childbirth. Lesotho, a country with one of the highest maternal mortality rates in SSA, is also underexplored in this research area. This cross-sectional study explored the levels of ANC literacy and the associated factors in 451 purposively sampled women in two districts in Lesotho using a structured questionnaire, making recourse to statistical principles. Overall, 16.4 per cent of the participants had grossly inadequate ANC literacy, while 79.8 per cent had marginal levels of such knowledge. The geographic location and level of education were the most significant predictors of ANC literacy, with the latter variable further subjected to post hoc margins test with the Bonferroni correction. The participants had the lowest scores on knowledge of danger signs in pregnancy and true signs of labour. Adequate ANC literacy is critical to reducing maternal mortality in Lesotho. Improving access to ANC education, particularly in rural areas, is recommended. This study also provides important recommendations critical to informing the national midwifery curriculum.

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