scholarly journals Diagnosis of Functional Dyspepsia on the basis of Rome III clinical diagnostic criteria in a tertiary care hospital: A cross-sectional observational study

2018 ◽  
Vol 9 (1) ◽  
pp. 55-60
Author(s):  
Kaushik Biswas ◽  
Rajdip Hazra ◽  
Sisir Chakraborty ◽  
Rajarshi Bose ◽  
Swadesh Garain

Background: Though functional dyspepsia (FD) is often a diagnosis of exclusion, whether minor mucosal gut pathology represents organic disease or FD, it still remains controversial.Aims and Objectives: The present study has been conducted to determine the accuracy of symptom based diagnosis of FD based on Rome III diagnostic criteria in a tertiary care center.Materials and Methods: Total 140 patients aged between 18-55 years of both sexes with upper abdominal symptoms without known or post investigational organic diseases, were included in this study. Patients fulfilling the Rome III criteria were diagnosed as FD and undergone upper GI endoscopy (UGIE). Those devoid of organic lesions were confirmed as ‘true FD’.Results: Out of 140 study patients, 100 patients fulfilled Rome III criteria (clinical FD) out of which 77 were confirmed as ‘true FD’ after UGIE with an accuracy of 83.57 %.Conclusion: Rome III clinical criteria can be applied to diagnose FD in a tertiary care center with some limitations. The authors suggest some modification of Rome III criteria.Asian Journal of Medical Sciences Vol.9(1) 2018 55-60

2018 ◽  
Vol 41 (3) ◽  
pp. 159-164 ◽  
Author(s):  
Madhabi Baidya ◽  
Mahfuza Shirin ◽  
Liton Chandra Saha

Background: Adequate neonatal transport is a key component of care of the sick newborns who require referral to tertiary care center. Poor transportation is one of the iatrogenic factors associated with greater neonatal mortality. Neonatal transport is the greatest challenge faced today in our country. The purpose of this study was to find out characteristics of transport of referred neonates and to idention the factors that contribute to mortality.Methodology: This cross sectional study was conducted in Dhaka Shishu (Children) Hospital from June 2013 to November 2013. Both term and preterm neonates who were referred within first seven days of life were included and those with gross congenital abnormalities and left against medical advice were excluded from the study. After enrollment, data were collected using a structured questionnaire including birth details, interventions before transportation, reasons for referral, and details of transportation. Outcome & duration of hospital stay were also recorded. Neonates who were expired considered as group I and who were survived considered as group II. The study variables were analyzed for their association with immediate outcome by applying chi square test and t test. P value <0.05 was considered significant.Results: This study found that out of 332 neonates 181 were expired with 54.5% mortality rate. One eighty one neonates who were expired, considered as group I and one fifty one neonate were survived, considered as group II. The mortality was significantly high in male neonates [RR 0.80 (0.66-0.97)] and neonates those delivered at home [RR 1.34(1.10-1.64)] (p<0.05). Perinatal asphyxia, pre-term low birth weight, neonatal sepsis were the main causes of referral. It was found that transportation without any referral note [RR 1.40 (1.14- 1.71)], no advice regarding maintenance of airway[RR 1.50(1.17- 1.92)]and keeping warm [RR 1.51(1.17-1.950], resuscitation on admission [RR 1.63(1.23-2.17)] and transportation required > 3hours [RR 1.36(1.09-1.69)] were associated with significantly higher mortality among referred transported neonates(p<0.05).Conclusions: This study found that male neonates, home delivery, transportation without any referral note, no advice regarding maintenance of airway and keeping warm, resuscitation needed on admission and prolonged transportation time were significantly associated with mortality of referred transported neonates.Bangladesh J Child Health 2017; VOL 41 (3) :159-164


Author(s):  
Priya Somu ◽  
Sakthi Narmatha D.

Background: Maternal mortality rate and Infant mortality rate remains high in India when compared to several other countries. Understanding and being aware about the basic care provided during pregnancy is an important factor to make the pregnant woman to utilize the antenatal care. Hence this study was planned to assess the existing knowledge of primi gravid mothers attending the tertiary health care center about the various antenatal care services provided.Methods: This cross-sectional study was conducted among the primi gravid females attending the outpatient department of Obstetrics and Gynecology in Sri Muthukumaran Medical College Hospital and Research Institute, Chennai during months of June 2018 to May 2019. A total of 280 primi gravid mothers were included in the study. Data was collected through one to one interview and analyzed using statistical package for social sciences (SPSS) version 17.Results: In this study 82.9%, 70.4%, 80.7% of the mothers were aware about consumption of IFA tablets, TT injection and adequate ANC visits, respectively. PNDT act was known to 76.1% of the participants. Only 12.5% of the primi mothers were aware about Janani Suraksha Yojna (JSY) scheme and 91.8% of the mothers were aware about Dr. Muthulakshmi Maternity Benefit scheme.Conclusions: Knowledge about ANC services was found to be fair among the primi mothers but not sufficient, which shows the need for the healthcare professionals to educate young woman even from adolescent age itself.


2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
S. Gautam ◽  
N. R. Bhattarai ◽  
K. Rai ◽  
A. Poudyal ◽  
B. Khanal

Background. Carbapenem resistance among Gram-negative isolates caused by the production of the metallo-β-lactamase (MBL) enzyme is being increasingly reported worldwide. One of the newly emerged metallo-β-lactamases is New Delhi metallo-β-lactamase. Data regarding its occurrence in hospital setting and percentage prevalence among different Gram-negative bacterial isolates are lacking in our part. This study has been undertaken for determining the presence of the bla NDM-1 gene among the clinical isolates of imipenem-resistant Gram-negative bacteria in a tertiary care center in Dharan, Nepal. Methods. A total of 75 imipenem-resistant Gram-negative isolates were studied. These were screened for metallo-β-lactamase (MBL) production by phenotypic assays such as double-disc synergy test (DDST) and combined disc diffusion test (CDDT). PCR was performed for the molecular detection of gene NDM-1. Ten-disc method was performed to detect the presence of ESBL, AmpC, carbapenamase, and K1 β-lactamase production. Results. Using the molecular method, bla NDM-1 was detected in 36% of the isolates. Phenotypically, double-disc synergy test (DDST) and combined disc diffusion test (CDST) detected MBL production in 38.7% and 37.3% of the isolates, respectively. Ten-disc method detected ESBL in 26.6% of the isolates, but none of the isolates was found to be AmpC, carbapenamase, and K1 β-lactamase producers. Conclusion. A high percentage of the NDM-1 producer was noted among imipenem-resistant GNB. Apart from performing only antimicrobial sensitivity test, phenotypic and molecular screening should be employed to find out the actual number of metallo-β-lactamase producers and the existence of the resistance gene.


2020 ◽  
Vol 3 (1) ◽  
pp. 26-31
Author(s):  
Ashish Thapa ◽  
Anugya Amatya ◽  
Roshan Parajuli

Introduction: Nearly half of people with diabetes don’t know they have it. It is often not diagnosed until complications appear. The aim of the study was to determine the prevalence of diabetes mellitus and prediabetes in patients presenting to the Emergency Department with incidental hyperglycemia, because the duration of hyperglycemia is a predictor of adverse outcomes, and there are effective interventions to prevent disease progression and to reduce complications. Methods: It was an observational cross-sectional study, 720 patients from Emergency Department of Kathmandu Medical College, Sinamangal were screened from December 2018 to March 2019 and a total of 128 patients with incidental hyperglycemia (>140mg/dl) were included. Patients with a previous diagnosis of diabetes, unstable patients and pregnant patients were excluded. Incidental hyperglycemia, fasting blood sugar, 2 hours postprandial blood sugar and HbA1c were noted, data entry was done in Microsoft Excel and analysis was done using the SPSS 24. Results: Total of 128 patients were enrolled for the study.10% of the patients had hyperglycemia and 34% among the hyperglycemic had the finding in the absence of history of diabetes. Incidental hyperglycemia ranged from 150-500 mg/dl. Among the incidental hyperglycemic, 29% and 36% had prediabetes and diabetes respectively. Incidental hyperglycemia was divided into four groups; <159, 160-179, 180-199 and >200 mg/dl, and each group was analyzed with the diagnostic criteria and the final outcome. It was found that each group correlated well with the diagnostic criteria and final outcome and was found to be statistically significant with p<0.0001 based on the Chi square test. Conclusions: Following the patients with incidental hyperglycemia in the Emergency Department, a significant number of undiagnosed diabetes or prediabetes can be diagnosed, early intervention can be started that can prevent progression from prediabetes to diabetes and risk of complications can be reduced.


2019 ◽  
Vol 6 (5) ◽  
pp. 2108
Author(s):  
A. Dharmalingam ◽  
Chandru Bhaskar ◽  
N. S. Raghupathy

Background: The knowledge and practice of exclusive breastfeeding has been prejudiced by demographic, social, cultural, biophysical, and psychosocial factors. About two-thirds of under-five deaths in India are associated with inappropriate infant feeding practices. Objective of this study was to assess the awareness, knowledge and practice of breastfeeding among the mothers attending to the tertiary care institute at Puducherry, India.Methods: This hospital-based, cross-sectional study was carried out among 150 postnatal mothers who attended immunization clinics, post-natal and paediatric wards at the tertiary care hospital at Puducherry collecting data about breastfeeding knowledge and practices using a structured interview.Results: The breastfeeding practices were significantly poorer in terms of initiation, feeding colostrums, timing and frequency of feeding and inclusion of pre-lacteal feeds among obese women compared to the normal weighted mothers. The breastfeeding knowledge and attitude was healthy among the mothers as depicted by the awareness of nutritive value of breast milk by majority (84%) of mothers.Conclusions: The mothers had poor knowledge regarding initiation of breastfeeding and administration of colostrum. There was a positive attitude about exclusive breastfeeding, frequency of feeding and social aspects of breastfeeding.


2021 ◽  
Vol 59 (238) ◽  
Author(s):  
Suman Thapa ◽  
Anupam Bista ◽  
Prashant Subedi ◽  
Aaradhana Adhikari ◽  
Sunil Pokharel

Introduction: Tuberculosis has high burden in developing countries like Nepal. This study aims to determine the prevalence of tuberculosis among patients admitted in the department of medicine of a tertiary hospital. Methods: A descriptive cross-sectional study of all the patients admitted to the tertiary care hospital from 1st January 2017 to 31st December 2019 was done. Ethical approval was obtained from Institutional Review Committee (Ref: drs2006181387). Convenience sampling method was used. A descriptive analysis of demographic, clinical and laboratory profile of patients was made using Microsoft Excel version 2016. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Results: Among 6829 patients admitted to the department of medicine, 209 (3.06%) (2.65-3.47 at 95% CI) patients were diagnosed with tuberculosis. Among them, 147 (70.33%) were males and the mean age was 49.77 years. Pulmonary and extra-pulmonary tuberculosis were present in 153 (73.20%) and 56 (26.79%) patients, respectively. Bacteriological confirmation was limited to 107 (70%) of pulmonary tuberculosis and 3 (5%) of extrapulmonary tuberculosis. Fever was the commonest presentation in 166 (79.42%) followed by cough in 164 (78.46%), anorexia in 108 (51.67%), weight loss 104 (49.76%), and others. Conclusions: The study showed that the prevalence of tuberculosis among admitted patients was higher than national prevalence.


2021 ◽  
Vol 19 (2) ◽  
pp. 44-48
Author(s):  
Sushil Paudel ◽  
Niraj Parajuli ◽  
Sudip Dahal ◽  
Sudarshan Paudel

Introduction: Sexually transmitted infections (STIs) are the diseases that are transmitted by sexual contact if a partner is infected with agent known to cause infection of genitalia. This group of diseases pose a huge public health problem. This study aims to provide an insight on the prevalence of STIs in a tertiary care center dedicated to civil servants. Methods: This is a retrospective cross-sectional study. All patients diagnosed with STI in a dermatology out-patient of Civil Service Hospital, a tertiary care hospital situated in Kathmandu over a period of two years from January 1 2018 to December 30 2019 were included in the study. The diagnosis was made by clinical and laboratory investigations. Results: The total number 157 cases of STIs were enrolled in this study, of which 119 (75.8%) were males and 38(24.2%) were females. The mean age of patients was 27.8±8.8 years, ranging from 15 to 60 years. Seventy three (46.5%) patients were married, while 81 (51.6%) patients were unmarried. Unmarried males were significantly more vulnerable to acquire STIs (p=0.005). Males were having significantly more premarital or extramarital sexual exposures as compared to females (p<0.001). The most common presentation was condyloma acuminata in 84(53.5%) patients. Consistent use of condom was reported only in 3 (2.5%) males and 1 (2.6%) females in this study. No association was noted between the education level attained to the practice of safe sexual methods (p=0.535). Conclusion: The proportion of males was higher than females in our study which might be due to the reluctances of female to see doctor for sexual problems. The level of education did not seem to make people aware of practicing safe sex. Sexual education seems must in all level of education.


Author(s):  
Priya Paari ◽  
Sindhuja T. P. ◽  
Shanthi Dhinakaran ◽  
Christina Mary P. Paul

Background: Asymptomatic bacteriuria (ASB) in pregnancy is a treatable risk factor for preterm delivery. India accounts for the highest preterm birth incidence in the world according to the WHO census released in November 2016. This study was aimed at finding the prevalence of asymptomatic bacteriuria, the spectrum of bacteria involved and the susceptibility pattern for the antimicrobials in the antenatal women attending a tertiary care hospital in urban Southern India.Methods: One hundred and eighty ante-natal patients without symptoms of ongoing urinary tract infection were enrolled to this study. Clean midstream urine sample was collected in a wide mouthed container and sample was analyzed by standardized microbiological testing techniques.Results: Out of the 180 ante-natal women included in the study, 11(6.1%) patients were found to have insignificant bacteriuria and 38(21.1%) had a significant bacteriuria. E. coli was the most frequently isolated organism and about 95% of the organisms were sensitive to Nitrofurantoin.Conclusions: More than a fifth of all pregnant women have ASB and E. coli is the most frequent pathogen encountered.


2021 ◽  
Vol 51 (2) ◽  
Author(s):  
Tatiana Noemí Uehara ◽  
Harumi Hashimoto ◽  
Federico Bazán ◽  
Adriana Tévez ◽  
Gladys Bravo ◽  
...  

Background and aims. The appropriate diagnosis of irritable bowel syndrome is critical due to its association with impaired quality of life and high health care costs. We aim to explore the proportion of subjects with irritable bowel syndrome by the Rome IV criteria at a tertiary care hospital and compare them with previous diagnostic criteria. Material and methods. We conducted a cross-sectional descriptive study in a tertiary care hospital located in Buenos Aires. There were included to the consecutive adult patients who consulted for abdominal disorders and in whom an organic pathology had been excluded. Subjects completed a gastrointestinal symptom questionnaire and the proportion of patients with IBS, according to Roma IV criteria, was compare with the proportion of those who met the previous criteria (Manning, Rome I, II and III). Results. Of 178 patients included, 58% met the diagnosis criteria for IBS using the Rome IV criteria. Of these, 98% were also Rome III positive, 76.7% IBS Rome II positive, 93% IBS Rome I positive and 99% IBS Manning positive. The agreement was very good with Rome III (kappa = 0.87), good with Rome I (kappa = 0.76) and good, but lower with Rome II (kappa = 0.73) and Manning (kappa = 0.66). Conclusions. Good diagnostic agreement was established between Rome IV and the previous IBS criteria, except with Rome II and Manning, which were lower.


Author(s):  
Attia Bari ◽  
Izza Imran ◽  
Nasir Ali Nawaz ◽  
Rizwana Kamran ◽  
Iqbal Bano ◽  
...  

Abstract Objective: To determine the awareness of postgraduate residents and nurses working in a tertiary care hospital about hand hygiene. Method: The cross-sectional study was conducted in October 2018 at The Children’s Hospital and the Institute of Child Health, Lahore, Pakistan, and comprised postgraduate residents and nurses. Data was collected using a 31-item self-administered inventory. Data analysis was done using SPSS 21. Results: Of the 360 subject, 152(%) were postgraduate residents and 208(%) were nurses. Overall score of knowledge 202(56%) was low compared to attitude 260(72%) and practice 283(78.6%). The combined score of all three domains was 245(68%), indicating moderate awareness. Postgraduate residents had significantly better knowledge 98(64%) compared to nurses 104 (50%) (p=0.01), while nurses had better attitude score 159(76.4%) compared to the residents 103(68%) (p<0.05). The practice subscale score was not significantly different between the groups (p>0.05). Conclusion: Both postgraduate residents and nurses showed moderately satisfactory knowledge, attitude and practice towards hand hygiene. Key Words: Hand hygiene, Healthcare-associated infections, Postgraduate residents, Nurses, Knowledge, Practices. Continuous...


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