Association of Obesity with Chronic Idiopathic Urticaria at Birat Medical College and Teaching Hospital

2020 ◽  
Vol 5 (2) ◽  
pp. 1087-1090
Author(s):  
Dilip Choudhary ◽  
Sabrina Yamu Shrestha

Introduction: A frequent association between metabolic syndrome with chronic idiopathic urticaria has been suggested by many studies but thorough investigations about the influence of obesity and overweight on chronic spontaneous urticaria has not been done.  Objectives: To find out the association of obesity with chronic idiopathic urticaria.  Methodology: Patients with chronic idiopathic urticaria were assessed for the body weight, height, body mass index, age of disease onset and duration of the disease.  Results: A total of 151 patients were enrolled in the study and among them 64 % were females as compared to 26 % males. The age of the patients included ranged from 17 years to 77 years. Among the patients included in study, 69 % of the patients suffering from CIU were found to be overweight and obese. The body mass index of the patient included ranged from 16.7 to 34.2 with mean of 24.3+/-4.3.  Conclusion: There is a relatively high incidence of urticaria among the people who are obese and overweight. 

2017 ◽  
pp. 57-61
Author(s):  
O.A. Dyndar ◽  

The problem of obesity and metabolic syndrome among the female population of Ukraine is extremely important, given the current trend toward increasing age of realization of reproductive function,. The prevalence of metabolic syndrome among women of reproductive age is 6–35%, fertility problems are found in 30-35% of women. The objective: to study the characteristics of metabolic disorders and hormonal condition of the reproductive system in women with obesity and the metabolic syndrome on pregravidarity stage depending on the body mass index and severity of metabolic syndrome. Patients and methods. We examined a total of 124 women with obesity and metabolic syndrome that appealed on pregravidar stage and 53 women who had no history of somatic and gynecological pathology. Antropometric studies, determination of blood pressure, examination of carbohydrate and lipid metabolism, evaluation of the endocrine status of the reproductive system, ultrasound examination of small pelvis organs were done. Results. In women of reproductive age, we observed increase of total cholesterol, triglycerides, low-density lipoproteins and decrease high-density lipoproteins, with a predominance of IIb and IV types of dyslipidemia. Insulin resistance was diagnosed in 28.3% of women And 47.4% – II and in 69.7% with III degree of obesity. Metabolic syndrome was diagnosed in 79.2% of patients with obesity of I, in 94.7% – II 100% III. The number of components of metabolic syndrome correlate directly proportional to the severity of obesity. The index of fertility with III degree of obesity increased to 2.7, hypoestrogenia marked with And hyperestrogenia from 50.7% of women in II and III degree of obesity, progesterona failure identified at 66.9%, hyperandrogenism in 58.8%, reduced sex-binding globulin in 83.0% of the observations. Conclusion. Pathological changes of the hormonal status of the female reproductive system on prepregnansy stage is directly proportional to depend on the body mass index number of components of metabolic syndrome and dysmetabolic disorders. Key words: obesity, metabolic syndrome, pregnancy planning.


2014 ◽  
Vol 48 (2) ◽  
pp. 236-241 ◽  
Author(s):  
Nyagra Ribeiro de Araújo ◽  
Raul Amaral de Araújo ◽  
Simone Maria Muniz da Silva Bezerra

This is a descriptive, retrospective study with cross-sectional quantitative approach, which aimed to relate the body mass index with events in the postoperative period of the myocardial revascularization surgery with use of extracorporeal circulation. The data collection period was between April and June/2012. Patients were divided according to the body mass index and classified as without excess of weight, overweight or obese. The data analysis was based on the descriptive statistics. The patients without excess of weight had more complications, especially those related to the lungs. Among overweight and obese individuals, the cardiovascular complications stood out. The obese subjects had the worse prognostic. Obesity and overweight did not have statistically significant association with a higher frequency of postoperative complications, in spite of the occurrence of cardiovascular complications in this group. The patients without excess of weight had higher risks of developing neurological events.



2018 ◽  
Vol 25 (1) ◽  
pp. 37-46 ◽  
Author(s):  
Hayat Didaoui ◽  
Méghit Boumediene Khaled

Abstract Background and aims: The aim of the current study was to assess the impact of environmental factors; food, socio-economic, and physical activity, on a group of obese children living in Ain-Defla (Center Algeria) and Sidi-Bel-Abbes (West Algeria). Material and methods: The protocol was carried out on a cohort of 125 school children aged of 5 to 11 years, including 64 boys and 61 girls, and 139 school children, including 93 boys and 46 girls in Ain Defla and Sidi-Bel-Abbes respectively. Concerning the classification of obesity and overweight, we referred to the International Obesity Task Force and the French References' curves. Results: Regarding dietary intake our results showed that 34% of students from both regions took their breakfast, compared to 66% who did not take. Furthermore, 73% of students skipped at least one meal, however 23% respected meals frequency i.e. 4 meals a day. Regarding socio-economic factors and physical activity, our findings showed that obesity rates were high (36%) among children whose fathers are workers. However, for mothers who are housewives, obesity increases among their children (88%). The relationship was reversed between the parents' education level and the Body Mass Index. We found an opposite relationship between Body Mass Index and physical activity, and investigated children use screen devices for long time periods. Conclusions: Our study showed a positive relationship between obesity and overweight and environmental factors.


2011 ◽  
Vol 57 (4) ◽  
pp. 7-12
Author(s):  
G V Katsiia ◽  
N P Goncharov ◽  
N A Chagina

We have studied steroid hormone profiles in young men with normal body mass index suffering obesity and metabolic syndrome. They showed a consistent tendency toward a shift in blood aldosterone level to the upper normal level and beyond. It was higher in patients with metabolic syndrome than with obesity. The testosterone levels displayed the downward trend from normal through obesity to metabolic syndrome values. The main predictors of testosterone dynamics in the course of development of obesity and metabolic syndrome were insulin concentration and BMI. Dynamics of dehydroepiandrosterone levels followed that of testosterone. It significantly decreased in men with metabolic syndrome compared with health subjects. Young men presenting with obesity and metabolic syndrome did not experience changes in morning and evening cortisol levels in peripheral blood. The study revealed the relationship between aldosterone levels and the development of metabolic syndrome mediated through the body mass index and the direct relationship between metabolic syndrome and testosterone dynamics.


2019 ◽  
Vol 5 (2) ◽  
Author(s):  
Yenni Zulhamidah ◽  
Ahmad Rafi Faiq ◽  
Etty Widayanti

The prevalence of obesity and overweight increase in this recent decades, and leading to a decrease in quality of life and various health problems. Some studies found that the sedentary behavior is correlated with obesity and overweight. However, sedentary behavior is as an indicator of high fat mass in several studies. The aim of this study was to investigate the relationship between sedentary behavior and body mass index to medical students of YARSI University in first and second year of their education. The research design used correlation study with the Cross Sectional approach, and a questionnaire instrument to determine sedentary behaviour of respondents in daily activities. Body mass index was classified into four categories. Data was analyzed using Pearson Chi Square tests. The results of this study showed significantly between sedentary behavior in daily activities and the body mass index


2020 ◽  
Vol 28 (1) ◽  
pp. 11-16
Author(s):  
AHM Mostafa Kamal ◽  
Khadeza Khatun ◽  
Shakil Shams ◽  
Begum Dilruba Kazi ◽  
Kazi Afzalur Rahman ◽  
...  

Context: Adequate knowledge about nutritional status of a community is necessary to have a comprehensive idea about its development process, as under-nutrition is one of the major health problems in developing countries. As an individual’s height and weight can be readily and inexpensively measured, body mass index (BMI) has become a popular heuristic approximation for body fatness in epidemiology and clinical practice. The BMI is the most common surrogate measure of obesity as well as nutritional assessment for individual. For this reasons an attempt has been taken to assess the nutritional status through the body mass index (BMI) among first year students of MBBS and B sc nursing course of government medical education institutes in Dhaka. Material and Methods: This descriptive type of analytic study was conducted in the Anatomy Department of Dhaka Medical College, Dhaka. The study sample was 177 individuals of first year students of MBBS and B.Sc nursing course admitted in the session of 2017-2018 in the Dhaka Medical College & Dhaka Nursing College, Dhaka. Body Mass Index (BMI) was calculated as student’s weight in kilograms divided by the square of the student’s height in meters (kg/m2). The warning sign of poor nutritional health was calculated according to the checklist adapted by the Nutrition Screening Initiative, American Academy of Family Physicians July 2001. With the help of statistical software SPSS-20 comparisons between the two groups were done. Result: The mean (±SD) height (meter), weight (kg) and BMI of groups MBBS and B Sc nursing were 1.63±0.09, 61.65±11.22, 23.11±3.53 and 1.56±0.07, 49.05±9.42, 20.15±3.47 respectively. Good nutritional health status was found 61.80% in MBBS and 53.30% in B Sc nursing groups. Conclusion: The present study showed that the BMI of first year students of MBBS course is higher than first year students of B Sc nursing course. J Dhaka Medical College, Vol. 28, No.1, April, 2019, Page 11-16


2020 ◽  
Vol 9 (6) ◽  
pp. 1646 ◽  
Author(s):  
Giorgio Radetti ◽  
Antonio Fanolla ◽  
Fiorenzo Lupi ◽  
Alessandro Sartorio ◽  
Graziano Grugni

(1) Objective: To compare the accuracy of different indexes of adiposity and/or body composition in identifying metabolic syndrome (MetS) in adult patients suffering from Prader‒Willi syndrome (PWS). (2) Study Design: One hundred and twenty PWS patients (69 females and 51 males), aged 29.1 ± 9.4 years, body mass index (BMI) 36.7 ± 9.9, were evaluated. The following indexes were assessed in each subject: body mass index (BMI), fat-free mass index (FFMI), fat mass index (FMI), tri-ponderal mass index (TMI), waist-to-height ratio (WtHR) and the body mass fat index (BMFI), which adjusts the BMI for the percentage of body fat and waist circumference. Thereafter, a threshold value adjusted for age and sex, which could identify MetS, was calculated for each index. (3) Results: A significant correlation was found among all indexes (p < 0.0001 for all). However, when the area under the curve (AUC) was compared, BMFI performed better than FMI (p < 0.05) and BMI better than TMI (p < 0.05), but only in females. (4) Conclusions: Besides small differences, all the indexes taken into consideration seem to have the same ability to identify MetS in adults with PWS. Consequently, the most easily calculated index, i.e., BMI, should be considered as the best choice. The use of thresholds appropriate for sex and age can further improve its accuracy.


2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
J. Cordes ◽  
G. Regenbrecht ◽  
M.W. Agelink ◽  
J. Zielasek ◽  
K.G. Kahl

In this naturalistic observational study carried out in an inpatient treatment setting we as yet surveyed the parameters of the metabolic syndrome. A weekly monitoring procedure was implemented. The analysis included data of 350 patients over a time of 12 weeks. The last observation carried forward method was applied. Additionally we are evaluating the informative value of visceral body fat percentage as measured by a body composition analyzer. The patients showed a weight increase over the first 12 weeks (mean increase: 0.87 kg, p < .001) as well as an increase of the body mass index (mean increase: 0.45 kg/m2, p < .001). Accordingly, waist circumference (mean increase: 1.06 cm, p = .007) and visceral fat index (mean increase: 0.19, p = .007) increased. No worsening of fasting glucose and blood lipid concentrations was detected. Spearmens coefficient indicated correlations between visceral fat index and body mass index (ρ = .77; p < .001), waist circumference (ρ = .70; p < .001), and triglyceride concentrations (ρ = .39; p < .001). Correlations between visceral fat index and fasting glucose (ρ = .18; p = .019), and visceral fat index and total cholesterol (ρ = .16; p = .049) were weak but also significant. In contrast, the HDL cholesterol showed a negative relation with ρ < -.39 at each point in time (p < .001).We conclude that psychiatric patients are at increased risk for the development of metabolic alterations during inpatient treatment. The possible underlying mechanisms of this interaction are discussed.


2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1353.1-1353
Author(s):  
K. Zhigulina ◽  
S. Spitsina

Background:Gout is an inflammatory and metabolic disease. Hyperuricemia can contribute to inflammation, hypertension and cardiovascular disease, adipogenesis and lipogenesis, impaired insulin and glucose metabolism, and the development of liver disease. In turn, non-alcoholic fatty liver disease is the most common chronic liver disease worldwide; is closely related to obesity, type 2 diabetes mellitus, dyslipidemia and other metabolic risk factors included in metabolic syndrome (MS). Interest in the problem of MS has not faded for many years, which is associated with its extremely rapid spread in the world.Objectives:To assess the cytokine status in patients with gouty arthritis (GA) in combination with metabolic syndrome (MS).Methods:There were 60 patients with reliable GA under observation. Among the surveyed men and women accounted for 60% and 40%, respectively, with an average age of 54 years, an average duration of the disease of 8 years. A family history of gout was present in 42% of patients. The onset of gouty arthritis was observed at 35.6 ± 10 years. Hypouricemic therapy was prescribed in 70% of patients. Thirty-six patients were diagnosed with the tofus form, 24 had no tofus. Patients were included in the study during arthritis remission. Blood samples were taken for general clinical and biochemical analyzes (ESR according to Westergren and uric acid levels were estimated), as well as for determination of serum concentrations of TNF-alpha and IL-6 by enzyme immunoassay.Results:The patients were divided into two groups: group 1 - 40 people with GA without signs of MS, group 2 - 20 patients with GA and MS. Patient groups were matched by sex, age, form and severity of the disease. In the 1st group, the body mass index ranged from 28.00 to 34.25 kg / m2, in the 2nd group - from 29.05 to 49.39 kg / m2. In patients with isolated gout, the waist in men averaged 96 cm, in women - 86.5 cm; in the 2nd group: in men - 98 cm, in women - 88 cm. Among the criteria for MS, in addition to abdominal obesity, in the 2nd group, arterial hypertension (in 64%), dyslipidemia (mainly types IIa and IIb) were significantly more frequent, violation of carbohydrate metabolism (fasting glycemic level 8.0 + 2.0 mmol / l), a higher level of uricemia (from 397.8 to 660.5 mmol / l) compared with the 1st group. The average level of IL-6 in the serum of patients in group 1 was 1.46 pg / ml, in group 2 - 14.03 pg / ml, the average level of TNF-alpha in group 1 was 0.51 pg / ml, in group 2 - 1.28 pg / ml.Conclusion:In GA patients with signs of MS, there is a significant increase in the production of key proinflammatory cytokines, namely IL-6, TNF-alpha. It was found that with a combination of MS and GA, the concentrations of IL-6, on average, 9.6 times, and TNF-alpha - 2.5 times, exceed the parameters of patients without signs of MS. A direct relationship was established between the expression of IL-6 and TNF-alpha with body mass index, as well as with insulin resistance and fluctuations in blood pressure. Thus, the cytokine imbalance is associated with increased risks of both cardiometabolic complications and the progressive course of GA.Disclosure of Interests:None declared.


2012 ◽  
Vol 13 ◽  
pp. 6-13 ◽  
Author(s):  
M. J. Müller ◽  
M. Lagerpusch ◽  
J. Enderle ◽  
B. Schautz ◽  
M. Heller ◽  
...  

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