scholarly journals Study of microbial flora in indwelling catheter, drains, CIVP lines and endotracheal tubes

2013 ◽  
Vol 3 (6) ◽  
pp. 469-471
Author(s):  
SB Pradhan ◽  
R Dhakhwa ◽  
CD Shrestha

Background: The use of indwelling devices like Urinary catheter, Drain tubes, Central intravascular catheter, endotracheal tubes has become routine practice in the medical field. Localized or systematic infection are frequent complications associated with extensive use of these devices, requiring its removal or may even be associated with life threatening consequences. Materials and Methods: Microbiological study was carried out among all the indwelling device samples received from 20th April 2011 to 19th April 2012 at Clinical Microbiology Laboratory, Department of Pathology, Kathmandu Medical College Teaching Hospital. Results: Out of total 205 samples (125 Foley’s catheters, 31 drain tubes, 29 central intravascular catheter lines and 20 endotracheal tubes) received during this study period, 38.4% urinary catheters, 23.33% drain tubes, 6.9% central intravascular catheter lines and 40.0% endotracheal tubes were found to have significant growth. Escherichia coli and Klebsiella were found to be the commonest organisms. Conclusion: The infection rates of indwelling devices used for various reasons are found to be very high. These infections have increased the morbidity and mortality of the hospitalized patients and also increased the duration of hospital stay. Thus aseptic measurements during insertion of these devices periodic change of these devices may help to overcome these complications. DOI: http://dx.doi.org/10.3126/jpn.v3i6.8995   Journal of Pathology of Nepal (2013) Vol. 3, 469-471

2018 ◽  
Vol 10 (2) ◽  
pp. 21-26 ◽  
Author(s):  
S Neupane ◽  
B Basnet

Background: Cutaneous adverse drug reactions (CADRs) range from minor reactions to several life threatening complications. Objectives: To study the clinical spectrum of cutaneous adverse drug reactions, determine the causative drugs responsible for the reactions and to assess the preventability.Methods: The study was carried out in the Department of Dermatology of Gandaki Medical College Teaching Hospital from June 2011 to June 2015. All the patients attending the Dermatology Outpatient Department and the patients admitted in the wards with suspected cutaneous adverse drug reactions to systemic drugs were included in the study. A detailed clinical history, including the history of drug intake was noted. Each case was assessed for its causality by using the WHO definitions. Data analysis was done using SPSS software.Results: There were 102 patients in total. The mean age of the patient was 32 ±15.7 years. Maximum patients belonged to the 21 to 30 years age group. There were 59 female patients and 43 male patients. Severe type of cutaneous adverse drug reactions was noted in 7.8% of patients. Antibiotics were responsible for most of the cutaneous adverse drug reactions. Cefixime was the most commonly incriminated drug. Exanthematous drug reaction was the most common type seen in 45%. Stevens-Johnson syndrome was the commonest type noted among the serious adverse drug reactions. Drug preventability was noted in 6% of patients.Conclusions: The commonest type of CADR noted was exanthematous type. Antibiotics were the commonest drug group involved in CADR. Six percent of CADR were preventable. J-GMC-N | Volume 11 | Issue 01 | January-June 2018, Page: 21-26


2017 ◽  
Vol 2 (1) ◽  
pp. 106-109
Author(s):  
Bhanubhakta Neupane ◽  
GMS Karki ◽  
P Dahal ◽  
SB Karki

IntroductionEctopic pregnancy is the most life threatening emergency in first trimester of pregnancy. Laparoscopic methods for treating ectopic pregnancy have made it preferred surgical technique over laparotomy. Most of the ectopic pregnancies can now be treated by laparoscopy.ObjectiveTo study outcome of laparoscopic management of ectopic pregnancy. MethodologyA hospital based cross-sectional study was conducted at Birat Medical College and Teaching hospital from May 2013 to April 2016. The informed consent was taken from patients. The collected data was entered in Microsoft Excel and analyzed SPSS.ResultsAll 89 cases of ectopic pregnancies were managed by laparoscopy. All were tubal pregnancies. Salpingectomy was done in 88 cases and salpingostomy in one case without any significant postoperative complications. There was no maternal mortality and no conversion to laparotomy  ConclusionTreatment of ectopic pregnancy by laparoscopy is effective with decreased postoperative morbidity.Birat Journal of Health Sciences Vol.2/No.1/Issue 2/ Jan - April 2017, page: 106-109


2013 ◽  
Vol 1 (2) ◽  
pp. 76-79 ◽  
Author(s):  
SB Pradhan ◽  
CD Shrestha

INTRODUCTION: Hospital acquired infections (HAI) are serious problems in the patient care and management despite antimicrobial therapy and advances in supportive care in developing countries. Regular cleaning following institutionalized guidelines of infection control policies can minimize the possibility of contamination and prevent the HAI so that the morbidity and mortality related to HAI will be reduced. MATERIALS AND METHODS: Descriptive analysis of the culture growth of the samples from different sites of the Kathmandu Medical College Teaching Hospital (KMCTH) environment from 4th March, 2011 to 4th April, 2012 was done. The swabs were taken before and after fumigation and disinfection and number of colonies grown were used to monitor the effectiveness of the intervention. The cultures and Gram staining were performed as per standard microbiological procedures in Clinical Microbiology Laboratory, Department of Pathology, Kathmandu Medical College Teaching Hospital. RESULTS: Almost all the floors of the hospital wards swabbed were contaminated with the bacteria. The bacteria that grew from the environment ranged from 50 to 140 colonies in Medical Intensive Care Unit and Special High Care Unit respectively. Common contaminants were Staphylococci spp., Gram negative diplococcic, and Gram positive. The Staphylococci spp. contaminated air in most of the wards. The number of colonies after fumigation and disinfection were drastically decreased from no growth to 15 colonies. CONCLUSIONS: Environment was contaminated with microorganisms. Even after regular cleaning and disinfection, bacterial growth was seen. To prevent any contamination prior HAI develops, hospital needs to develop programmes for the implementation of good infection control practices. DOI: http://dx.doi.org/10.3126/ijim.v1i2.7410 Int J Infect Microbiol 2012;1(1):76-79


2020 ◽  
Vol 9 (2) ◽  
pp. 45-49
Author(s):  
Pramod Sharma Gautam ◽  
Uday Chandra Prakash ◽  
Subreena Dangol

Background: The eye and vision related problems that results from continuous use of computers and other visual display terminals for extended period of time leads to computer vision syndrome. Due to rapid digitalization in human life, the risk of developing it has also increased in many folds. So, with an aim of determining the prevalence and level of awareness of computer vision syndrome among computer users along with their attitude and practices to prevent it, this study was conducted in the office employees who use computer for a considerable period of time. Materials and Methods: A hospital based observational descriptive study was conducted in the out-patient department of Ophthalmology in Nobel Medical College and Teaching Hospital, Biratnagar, where 105 employees working in different work stations of same institution were enrolled. A questionnaire and the clinical findings were used to collect data. Results: About 80% of the employees were using computer for about (8-11) hours per day. Prevalence of computer vision syndrome noted was (92.4%) with low level of knowledge (85.7%) about it. About 45% of them wore glasses for their refractive errors but attitude and practices in work place to prevent the bad effects of using visual display terminals were found to be lacking (53.3%). Burning sensation in the eye, headache, ocular irritation and itching and neck, shoulder or back pain were the common symptoms. Around (60-70)% of the eyes tested positive for dry eye. Conclusion: Lack of awareness of computer vision syndrome and lack of personal protective measures were associated with its high level of prevalence.  


KYAMC Journal ◽  
2018 ◽  
Vol 9 (3) ◽  
pp. 133-135
Author(s):  
Joya Debnath ◽  
Arpan Kumar Basak ◽  
Md Zubaidur Rahman ◽  
Anujit Saha

Background : Self poisoning with organophosphate pesticides is a major health problem in world wide. Organophosphorus compound poisoning is a very common toxicological emergency encountered at Mirzapur in Tangail. It is particularly common among the rural agricultural worker's which comprise a substantial group of the population of this region.Objective: The objective of this study was to find out the incidence, frequency, pattern of poisoning, outcome and aetiological aspect of Organo phosphorus poisoning patient admitted in Kumudini Women's Medical college Hospital.Methods: A total 366 cases of OPC poisoning were analysed during 1 year from January 2015 to December 2015. The emphasis was given on age, sex, socio-economic status, occupation, motive of poisoning, types of compound consumed its quality, place, distance from referral place and the ultimate outcome.Results: Young population of rural background, particularly agricultural workers were the commonest patients (51.91%). The most common motive of poisoning was with a suicidal intent, both in males (27.59%) and females (66.39%). Financial crisis was one of the most common reasons analysed as the motive behind the poisoning (54.20%). Three hundred forty four Patients recovered and 22 were expired. The major cause of death in these cases was respiratory failure followed by multi-organ failure.Conclusion : Strict of the pesticide act and involving a new policy by the government to educate the public and youth in large about the dangerous, life threatening effects of Organophosphorus compound could help amelerioating the harmful effects of such poisoning.KYAMC Journal Vol. 9, No.-3, October 2018, Page 133-135


2019 ◽  
Vol 12 (1) ◽  
pp. 25-30
Author(s):  
B Parajuli ◽  
G Pun ◽  
S Ranabhat ◽  
S Poudel

Objective: To study the spectrum of histopathological diagnosis of endometrial lesions and their distribution according to age. Methods: All the endometrium samples obtained by the procedure of dilatation and curettage and hysterectomy sent for histopathological examination at Pathology Department of Gandaki Medical College Teaching Hospital, Pokhara, Nepal. The study duration was total 12 months ranging from July 2016 to June 2017. All the endometrial samples were processed, sectioned at 4 - 6 μm and stained with routine H & E stain. Patient’s data including age, sex, procedure of the biopsy taken and histopathological diagnosis were noted. A pathologist, using Olympus microscope, reported the slides. Cases were reviewed by a second pathologist whenever necessary. Results: A total of 128 cases were studied. The most common histopathological diagnosis was proliferative endometrium (28.9%) followed by disorder proliferative endometrium (15.65%). Most of the patients were in age group 36 - 45 years comprising 32.03%. Hydatidiform mole comprised of 7.03% and among Hydatidiform mole, partial mole was more common. Dilatation and curettage (82.8%) was the common procedure in compare to hysterectomy for the evaluation of endometrial lesions. Conclusions: In this study, we observed a variety of endometrial lesions. Most of them are benign; among benign, proliferative endometrium was the common histopathological diagnosis followed by disorder proliferative endometrium. Most common presenting age group was found to be at 36 - 45 years. In evaluation of hydatidiform mole, partial mole was more frequent in compare to complete mole. Conventional dilatation and curettage is the preferred method in developing countries with limited resource to screen endometrial lesion and therefore biopsy should be sent for histopathological examination. Thus histopathological examination of routinely stained hematoxylin and eosin is readily available and widely accepted standard technique for evaluation of the endometrial lesions.


2017 ◽  
Vol 6 (1) ◽  
pp. 40-47
Author(s):  
M Lopchan ◽  
G Gurung ◽  
L Rajbanshi ◽  
C Osti ◽  
A Baniya

Nosocomial infections (NIs) are one of the most important health issues, particularly in developing countries, because these infections cause high mortality and morbidity, and economic and human resource loss as a consequence Nosocomial infections can be defined as those occurring within 48 hours of hospital admission, 3 days of discharge or 30 days of an operation. Many studies have examined risk factors of nosocomial infections. However, knowledge of frontline workers (attendants) in infection prevention have been reported rarely in developing countries. The aim of this study was to investigate the knowledge of attendants working in different wards and OPDs about infection prevention. S: Data were collected from 100 attendants in Chitwan Medical College Teaching Hospital. Regarding the knowledge on hand washing, gloving and personal accessories for Infection Prevention, majority of the respondents had good knowledge ranging from 94-100%. Though hospital has established Infection Prevention Committee and regular training on infection prevention is provided to all the staffs, the data indicated that only 68% respondents were benefitted by the infection prevention training and proper use of virex solution to disinfect the equipment’s was found unsatisfactory. Infection control is the responsibility of all Health Care Facility (HCF) personnel. The goal of the infection control policies are to identify and reduce risks of acquiring and transmitting infections among patients, staff, students, volunteers, contract service workers, and visitors Although significant effort has been made to reduce the Nosocomial infections, regular training as well as monitoring supervision will enhance the capacity of the health care providers and front line workers for cleaning services they are our valued respondents.DOI: http://dx.doi.org/10.3126/jcmc.v6i1.55069


Author(s):  
Iqbal Ahmad ◽  
Ummer Farooq Raina ◽  
Muhammad Yousaf ◽  
Liaqat Jalal ◽  
Samia Saeed ◽  
...  

2021 ◽  
pp. 9-9
Author(s):  
Neelkamal Gupta ◽  
Mangtani Jitendra K ◽  
Khandelwal Dheeraj K

INTRODUCTION:Apeptic ulcer is a defect in the upper gastrointestinal mucosa that extends through the muscularis mucosa into deeper layers of the gut wall. Non-steroidal anti-inammatory drugs (NSAIDs) are the major risk factors for peptic ulcer disease.Long-term use of NSAIDs, however, can cause gastrointestinal (GI) ulcers and potentially life-threatening ulcer complications. MATERIALAND METHOD: The present study was conducted on 100 patients of peptic ulcer of either sex in Department of Surgery, Mahatma Gandhi Medical College & Hospital, Jaipur. History of any other co morbid illness and any drug being taken with its time duration were recorded in detail. RESULT AND DISCUSSION: From this study, it was observed that among the 69 patients of duodenal perforation, 73.91% were taking NSAID. Similarly among the 31 patients of gastric perforation 80.64% were taking NSAID. Overall total 76% patients were taking these drugs. CONCLUSION: It is concluded from this study that a strong statistical correlation was found between use of NSAIDs and peptic ulcer perforation.


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