scholarly journals Profile of Organophosphorus Poisoning

KYAMC Journal ◽  
2018 ◽  
Vol 9 (3) ◽  
pp. 133-135
Author(s):  
Joya Debnath ◽  
Arpan Kumar Basak ◽  
Md Zubaidur Rahman ◽  
Anujit Saha

Background : Self poisoning with organophosphate pesticides is a major health problem in world wide. Organophosphorus compound poisoning is a very common toxicological emergency encountered at Mirzapur in Tangail. It is particularly common among the rural agricultural worker's which comprise a substantial group of the population of this region.Objective: The objective of this study was to find out the incidence, frequency, pattern of poisoning, outcome and aetiological aspect of Organo phosphorus poisoning patient admitted in Kumudini Women's Medical college Hospital.Methods: A total 366 cases of OPC poisoning were analysed during 1 year from January 2015 to December 2015. The emphasis was given on age, sex, socio-economic status, occupation, motive of poisoning, types of compound consumed its quality, place, distance from referral place and the ultimate outcome.Results: Young population of rural background, particularly agricultural workers were the commonest patients (51.91%). The most common motive of poisoning was with a suicidal intent, both in males (27.59%) and females (66.39%). Financial crisis was one of the most common reasons analysed as the motive behind the poisoning (54.20%). Three hundred forty four Patients recovered and 22 were expired. The major cause of death in these cases was respiratory failure followed by multi-organ failure.Conclusion : Strict of the pesticide act and involving a new policy by the government to educate the public and youth in large about the dangerous, life threatening effects of Organophosphorus compound could help amelerioating the harmful effects of such poisoning.KYAMC Journal Vol. 9, No.-3, October 2018, Page 133-135

2017 ◽  
Vol 12 (04) ◽  
pp. 238-248
Author(s):  
Mario Torres ◽  
Hazel Luyon-Tabo ◽  
Steven Salibay ◽  
Cristina Cabanacan-Salibay

AbstractThis article aims to discuss the issues about Schistosoma japonicum infection in the Philippines based on the research findings of previous studies. This includes reviews about the nature of schistosomiasis, with emphasis on its effects on children. The review also discusses the mode of transmission of the parasite, etiology, and epidemiology, and relates these factors to the persistence of S. japonicum as a major health problem in the Philippines. The efforts, preventive measures, and recommended actions of the government are also mentioned and have been taken into consideration in strengthening the eradication measures against S. japonicum. This review further analyzes the risk factors associated with the infected individuals. Some measures and practices that may contribute to the prevention of S. japonicum infection are highlighted.


Author(s):  
Nikhil Gupta ◽  
RS Maniram ◽  
Garima Vijayvergiya

Background: Malaria is a major health problem all over the globe. WHO recorded that 228 million people suffered and 405000 died due to malaria in 2018. Severity of malaria is known to be the cause of serious morbidity and mortality in poor population. Understanding of its current symptoms and associated complication can help in early diagnosis. Aims and objectives: To study the malarial complications among the adult patients. Materials and Methods: Hundred malaria patients were studied at Gandhi Medical College and associated with Hamidia Hospital from Jan 2019 to Dec 2019. For all the subjects’ medical history, demographic details and medical complications were recorded. Results: Major symptoms at the time of admission were fever, nausea and headache. Major complications in SM patients were severe anemia, prostration, hyperpyrexia (9%) respiratory distress in (6%), thrombocytopenia (70%), low leukocyte count (21%), and cerebral malaria was recorded in 4%. No mortality was recorded during this study. Conclusion: Severe anemia, prostration, hyperpyrexia, ARDS, thrombocytopenia and low leukocyte count are the major complications of SM. Keywords: nausea, anemia, prostration, hyperpyrexia, thrombocytopenia


Author(s):  
Dr. Ajay Kumar Mishra ◽  
Dr. Prabhat Kumar Budholia

Obesity is a major health problem of excessive adipose tissue accumulation in body which leads to problem in Asian countries like India as a result of rapidly changing life style which involves consumption of calorie rich food with lack of physical activities. While the complication of obesity such as cardiovascular disease, diabetes and osteoarthritis are well known, but less emphasis is traditionally placed on the effects of obesity on the respiratory system. Obesity is responsible for lessening the lung volume and capacities by reducing both lung and chest wall acquiescence and also there is an increase in resistance to outflow of air through the airways. Purpose of present study is to establish a relationship between Forced Vital Capacity and Body Mass Index (BMI). The present study was undertaken in department of Physiology in Netaji Subhash Chandra Bose Medical College, Jabalpur MP in year 2018. The subjects comprised of both male and female 50 individuals came to Physiology department for Pulmonary function test from other departments of the college. After explaining and training the subjects Spirometry of all individuals was done by Computerised Spirometer in well ventilated room, after written consent in Department of Physiology. Tools used in present study were chi square, t-test etc.


Anaemia during pregnancy is a major health problem throughout the world. The prevalence of anaemia in pregnancy is 41.8% globally and 46% in Bangladesh. It affects both the mother and the baby simultaneously. Women often become anaemic during pregnancy because the demand for iron is increased due to the physiological need for pregnancy. This cross-sectional study was carried out in Savar Gonoshasthaya Kendra project area in Dhaka district. Ninety-Five pregnant women of different gestational ages were selected purposively. Haemoglobin level was estimated by cyanomeath haemoglobin method in the laboratory of Gonoshasthaya Samaj Vittik Medical College Hospital, Savar. Among 95 pregnant women, 41.1% was in 20-24 years age group. The mean age of the respondents was 23.74 years. In terms of socio-economic status, 54.7% of the respondents came from lower middle-class family. 7.4% of the respondents had no formal education, 54.7% had primary level education and only 6.3% had higher education. Maximum of the respondents (88.4%) were housewife. This study revealed that the prevalence of anaemia among pregnant women was 51.6%. Among 51.6 % of the anaemic respondents, 23.2% were mildly anaemic, 26.3% were moderately anaemic and 2.1% were severely anaemic.


2021 ◽  
Vol 4 (2) ◽  
Author(s):  
Chengxin Xu ◽  
Yixin Liu

Associating a life-threatening crisis with a geographic locality can stigmatize people from that area. However, such a strategy may reduce the public blame attributed to the government because the perceived foreign threat establishes a scapegoat, which transfers that blame. In the context of the COVID-19 pandemic, we investigated whether the “Chinese Virus” label placed on COVID-19 has elicited opposition to Chinese immigrants and reduced public blame attributed to the federal government. We used a survey experiment during the COVID-19 pandemic, and a list experiment to measure perceived threat. The descriptive analysis suggested a negative attitude toward Chinese immigrants overall, in which conservatives expressed stronger negative attitudes than did liberals and moderates. While labelling COVID-19 as the “Chinese Virus” did not make a difference overall, our exploratory results shows that it led to a significant increase in liberals’ perception that Chinese immigrants are a threat. However, the “Chinese Virus” label showed no effect overall in reducing the extent to which either liberals or conservatives’ attributed blame to the federal government.


Healthcare ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 1175
Author(s):  
Ramalingam Shanmugam ◽  
Lawrence Fulton ◽  
Zo Ramamonjiarivelo ◽  
José Betancourt ◽  
Brad Beauvais ◽  
...  

COVID-19 (otherwise known as coronavirus disease 2019) is a life-threatening pandemic that has been combatted in various ways by the government, public health officials, and health care providers. These interventions have been met with varying levels of success. Ultimately, we question if the preventive efforts have reduced COVID-19 deaths in the United States. To address this question, we analyze data pertaining to COVID-19 deaths drawn from the Centers for Disease Control and Prevention (CDC). For this purpose, we employ incidence rate restricted Poisson (IRRP) as an underlying analysis methodology and evaluate all preventive efforts utilized to attempt to reduce COVID-19 deaths. Interpretations of analytic results and graphical visualizations are used to emphasize our various findings. Much needed modifications of the public health policies with respect to dealing with any future pandemics are compiled, critically assessed, and discussed.


Author(s):  
Arvind Singh Kushwaha ◽  
Anshika Kushwaha ◽  
Neha Kushwaha

Background: Giving colostrum to a newborn has been called the “first immunisation” of the child. Colostrum and breast milk have definite anti-infective properties and have shown to have an impact on reducing specific morbidity and mortality rates among infants. The objectives of the study were to determine the level of knowledge about early initiation of breast feeding amongst mothers and to study determinants of initiation of breast feeding.Methods: Cross-sectional analytical study was carried out at a tertiary care hospital of a medical college in Pune. Systematic random sampling method was used.Results: The subjects came predominantly from joint families, urban area, Hindu by religion and Class II Socio economic status (Kuppuswamy classification). Majority of (84.23%) mothers responded that they initiated breast feeding within 1 hour after birth. Most (95.25%) of the mothers agreed for giving colostrums. About half of the mothers interviewed believed that breast milk is more nutritious (49.5%) while 28% mothers said that feeding babies with breast milk protects them against infections.Conclusions: All doctors and paramedical personnel in the Government and private institutions ensure that lactation begins immediately after birth and prelacteal feeds are withheld.


2018 ◽  
Vol 17 (4) ◽  
pp. 481
Author(s):  
Rakul Nambiar ◽  
Dae Dalus ◽  
Anjali Srikumar

Hoarseness is a common clinical condition with underlying causes which can vary from reversible and benign to life-threatening and malignant. Cardiovocal syndrome may cause hoarseness secondary to left recurrent laryngeal nerve palsy when the recurrent laryngeal nerve is mechanically affected due to enlarged cardiovascular structures. We report a 28-year-old male who presented to the Government Medical College, Thiruvananthapuram, India, in 2013 with hoarseness. He had undergone irregular treatment for pulmonary tuberculosis (TB) two years previously. Fiber-optic laryngoscopy indicated left vocal cord palsy and a computed tomography scan of the chest revealed features of pulmonary hypertension with extensive enlargement of the pulmonary arteries. An echocardiogram confirmed severe pulmonary arterial hypertension with severe tricuspid regurgitation. He was diagnosed with left recurrent laryngeal palsy secondary to cardiovocal syndrome. Although reports exist of recurrent laryngeal palsy in TB, this case appears to be the first to report cardiovocal syndrome in a patient treated for pulmonary TB.


2019 ◽  
Vol 9 (1) ◽  
pp. 1453-1456
Author(s):  
Niraj Nepal ◽  
Prabesh Kumar Choudhary ◽  
Nirajan Mainali

Background: Malaria is a major health problem especially in developing countries. It is a major causeof morbidity and mortality especially in the tropics. There are several hematological changes in thisparticular disease, which includes thrombocytopenia, anemia , atypical lymphocytosis and infrequentlyintravascular coagulation. The aim of the study is to detect and compare the severity of varioushematological changes, especially thrombocytopenia in the particular type of malaria.Materials and Methods: This was an observational study done on the patients attending the outpatientand inpatient departments clinically suspected for malaria in Nobel Medical College, Biratnagar, Nepal.Thick and thin slides were made and stained with Leishman’s stain for malarial parasites and also antigentests were included wherever necessary. Other tests included were, complete blood counts.Results: Amongst the included 800 patients with suspicion of malaria, 135 (17%) patients demonstratedmalarial parasites on peripheral blood film. Male predominance in male to female predominance of 3.5:1was observed. Total number of 120 out of 135 had thrombocytopenia. Thrombocytopenia was observedhigher in P. Vivax (79.3%) followed by Mixed infection (17%) and P. falciparum (3.7%) respectively.Conclusion: Anemia with mainly thrombocytopenia was mainly seen in P. Vivax type followed by P.Falciparum. Since thrombocytopenia is associated with malaria, which is demonstrated in our study,treating physicians should keep malaria as one of the differential diagnosis in patients with fever and lowplatelets.


Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2304
Author(s):  
Lais Pessanha de Carvalho ◽  
Andrea Kreidenweiss ◽  
Jana Held

Malaria is one of the most life-threatening infectious diseases and constitutes a major health problem, especially in Africa. Although artemisinin combination therapies remain efficacious to treat malaria, the emergence of resistant parasites emphasizes the urgent need of new alternative chemotherapies. One strategy is the repurposing of existing drugs. Herein, we reviewed the antimalarial effects of marketed antibiotics, and described in detail the fast-acting antibiotics that showed activity in nanomolar concentrations. Antibiotics have been used for prophylaxis and treatment of malaria for many years and are of particular interest because they might exert a different mode of action than current antimalarials, and can be used simultaneously to treat concomitant bacterial infections.


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