Antibiogram of Urinary Escherichia coli isolated in Sir Salimullah Medical College Mitford Hospital, Dhaka.

2013 ◽  
Vol 5 (2) ◽  
pp. 23-26
Author(s):  
Sanya Tahmina Jhora ◽  
Shikha Paul ◽  
Bilkis Ara Begum ◽  
Abul Quashem Chowdhury
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Antibiotic Sensitivity ◽  
Urine Samples ◽  
Medical College ◽  
Sensitivity Pattern ◽  
Highly Sensitive ◽  
Low Sensitivity ◽  
Tract Infections ◽  
Inpatient Department

Urinary tract infections (UTIs) are one of the most common infectious diseases & an important cause of morbidity in general population. More than 90% of all uncomplicated UTI s are caused by Esch. coli infection. The study was carried out in Department of Microbiology of Sir Salimullah Medical College & Mitford Hospital (SSMC& MH) Dhaka from October 2002 to September 2003. A total of 749 urine samples were studied of which 414 (55.27) showed significant growth. Among the 414 isolates, E sch. coli was the most predominant (82.61%) organism. Esch. coli was highly sensitive to Imipenem (95.02%) followed by Ceftriaxone (86.84%), Cefuroxime (67.54%), Gentamicin (66.08%), and Ceftazidime (55.84%) respectively. Low sensitivity patterns were shown against Nitrofurantoin (44.73%) & Ciprofloxacin (40.64%). The sensitivity to other antibiotics varied from 23.39% to as low as 2.63%. The aim of the present study was to observe the antibiotic sensitivity pattern of isolated Esch. coli from urine samples of patients admitted in inpatient department or visited the out patient department of Sir Salimullah Medical College & Mitford Hospital (SSMC& MH) Dhaka.DOI: http://dx.doi.org/10.3329/bjmm.v5i2.16934 Bangladesh J Med Microbiol 2011; 05 (02): 23-26

scholarly journals Pattern of antibiotic sensitivity of bacteria causing urinary tract infection in a private medical college hospital in Dhaka

2015 ◽  
Vol 14 (1) ◽  
pp. 70-74
Author(s):  
Shahin Sultana ◽  
Marium Khatun ◽  
Md Khoybar Ali ◽  
Nurunnahar Mawla ◽  
Nayareen Akhter
Keyword(s):  
Urinary Tract ◽  
Medical Science ◽  
Antibiotic Sensitivity ◽  
Urine Samples ◽  
Resistance Pattern ◽  
Medical College ◽  
Frequency Rate ◽  
Sensitivity Pattern ◽  
Tract Infections ◽  
Culture Positive

Background: Urinary tract infections (UTI), being the most common infections diagnosed in community and hospital, are to be treated scrupulously considering the type of infecting organism and its antibiotic sensitivity and resistance pattern. Aims and objectives: The aim of the present study was to observe the antibiotic sensitivity pattern of isolated uropathogens from urine samples of patients attending at Shahabuddin Medical College & Hospital, Dhaka, during the period of July 2008 to June 2009. Result: A total of 555 urine samples were studied; of which 84 (15.13%) were culture positive. Among 84 culture positive cases, 84 isolates were identified. Among the isolates, E.coli was the most predominant 61 (62.88%) followed by Enterococci 11 (11.34%), proteus 4 (4.13%) and Pseudomonas 3 (3.09%). Whereas Staphylococcus saprophyticus and Klebsiella showed frequency rate of 2 (2.06%) for each. However Gram positive cocci showed lowest frequency rate of 1 (1.03%). All of the isolates were sensitive to Netilmicin. The majority of isolates were sensitive to Imipenam (92.3%) followed by Amikacin (91.1%), Meropenam (83.3 %), Tetracycline (70%). Sensitivity & resistance rate were same (50%) in Vancomycin & Cefodoxime. Where complete (100%) resistance was shown to Ampicillin, Azithromycin and Cefoxitin. However all isolates were poorly sensitive to cotrimoxazole (35.7%), ciprofloxacin (43%) and nitrofurantoin (44.8%). Conclusion: So, routine urine culture and susceptibility before therapy should be encouraged and periodic evaluation of predominant organisms and their antimicrobial susceptibility pattern should be studied for appropriate selection of antibiotic for effective management of UTI cases.DOI: http://dx.doi.org/10.3329/bjms.v14i1.21562 Bangladesh Journal of Medical Science Vol.14(1) 2015 p.70-74

scholarly journals POLA DAN SENSITIVITAS KUMAN DI PENDERITA INFEKSI SALURAN KEMIH

2018 ◽  
Vol 12 (3) ◽  
pp. 110
Author(s):  
Samirah . ◽  
Darwati . ◽  
Windarwati . ◽  
Hardjoeno .
Keyword(s):  
Escherichia Coli ◽  
Retrospective Study ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Successful Treatment ◽  
Clinical Microbiology ◽  
Urine Samples ◽  
Resistance Pattern ◽  
Sensitivity Pattern ◽  
Tract Infections

The bacterial and sensitivity pattern towards antimicrobials on urinary tract infections (UTI) patients are very important to beknown by clinicians to get a successful treatment. The bacterial and sensitivity pattern towards antimicrobials will be changed in differentplace and time, so that those should be analyzed routinely. To evaluate the bacterial and antimicrobials resistance pattern on urinarytract infections patients. A retrospective study on 220 urinary samples in January until December 2004 at Clinical Microbiology subunit of Dr.Wahidin Sudirohusodo hospital . Of 99 samples of UTI, Prevalence of UTI in woman (54.5%) were higher than man (45.5%).Most of sample (28 samples) were found in 0 to 15 years group. The most bacteries in urine were Escherichia coli (39.4%) and Klebsiella(26.3%). Amikacin was sensitive to all bacteries, while amoxicilin and ampicilin were resistance. Prevalence of UTI in women werehigher than in men. Incidens of UTI was highest in children group. The most bacteries in urine samples were Escherichia coli. Amikacinwas sensitive to all bacteries, while Amoxicilin and Ampicilin were resistance.

scholarly journals Epidemiological and Bacteriological Profile of Urinary Tract Infection and the Antibiotic Sensitivity Pattern of Causative Organisms in National Medical College and Teaching Hospital - A Retrospective Cross-Sectional Study

Med Phoenix ◽  
2020 ◽  
Vol 5 (1) ◽  
pp. 40-45
Author(s):  
Sagar Ghimire ◽  
Sanjay Paudel ◽  
Shahrukh KC ◽  
Pragya Gautam ◽  
Vikash Paudel
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Teaching Hospital ◽  
Antibiotic Sensitivity ◽  
Cross Sectional ◽  
National Medical College ◽  
Medical College ◽  
National Medical ◽  
Bacteriological Profile ◽  
Sensitivity Pattern

Background: Urinary tract infections (UTIs) are one of the most common infectious conditions seeking treatment. There are varieties of microorganisms associated. The bacteriological investigations are incomplete without antibiotic sensitivity test of the isolate. Our aim is to determine age and sex distribution of UTI, bacteriological profile, and antibiotic sensitivity pattern of the organisms. Materials and Methods: A retrospective cross-sectional observational study of records of patients with clinically suspected UTI from Kartik 2076 to Magh 2076 was conducted at National Medical College and Teaching Hospital (NMCTH). It included both inpatient and OPD visit patients who submitted their clean-catch midstream urine sample for culture and antibiotic sensitivity at Microbiology lab of NMCTH. Result: Out of 385 patients, 103 (26.75%) showed bacterial growth. Escherichia coli (47.58 %) was the most common organism followed by Staphylococcus sps. (18.45%) and Klebsiella sps.(17.47%) respectively. There was female dominance (62.13%) but male were predominantly affected in children and older population. The most common age group for UTI was 21-30 years (mean age 25 years) and females were more affected than males. The most common pathogen was Escherichia coli, followed by Staphylococcal sps. and Klebsiella. All the organisms showed best sensitivity to tigecycline (100%). Conclusion: This study highlights the common pathogens causing UTI and their antibiotic sensitivity patterns which could help clinicians in starting rational empirical antibiotic therapy for such patients while awaiting urine culture reports.   

scholarly journals Isolation, identification and antibiotic sensitivity pattern of Escherichia coli isolated from various clinical sample in a tertiary care hospital, Jaipur, Rajasthan, India

2020 ◽  
Vol 8 (5) ◽  
pp. 1774
Author(s):  
Bitopan Das ◽  
Mrinmoy Sarma ◽  
Rohit Kumar ◽  
Palashi Borah ◽  
Sushama Sinha ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Bacterial Infections ◽  
Clinical Sample ◽  
Tertiary Care ◽  
Antibiotic Sensitivity ◽  
Resistant Bacteria ◽  
Care Hospital ◽  
Sensitivity Pattern ◽  
Tract Infections

Background: Escherichia coli is one of the most frequent causes of many bacterial infections, including Urinary Tract Infections (UTI), blood stream infections, otitis media, pneumonia, meningitis, traveler’s diarrhoea, enteric infections and systemic infections. This study was done with the aim to surveying antibiotic sensitivity pattern of isolated Escherichia coli in both sex attended in NIMS Hospital, Jaipur under the taken time period.Methods: In this cross-sectional study, 62 Escherichia coli were isolated from various clinical specimens of the patients attending both OPD and IPD. The strains were selected using the laboratory standard methods and culture-specific. The antibiotic susceptibility testing was performed using Kirby-Bauer disk diffusion method.Results: Out of total 62 isolates of Escherichia coli 26(41.93%) isolates were from male while 36(58.064%) from female patients. Maximum sensitivity were shown by Polymyxin B and Colistin i.c 100% followed by Nitrofuratonin 82.5% followed by Meropenem 79.03%, Aztreonam 72.58%, Piperacillin/ Tazobactam and Ciprofloxacin 61.30%, each Amikacin 56.45%, Imipenem 54.83%, Ofloxacin 45.16%, Cefepime 43.54%, Ceftazidime 38.71%, Gentamycin and Ceftriaxone 37.09% each, Cefotaxime 30.64%, Norfloxacin 27.5%. Maximum resistance shown against Norfloxacin 72.5%, followed by Gentamycin and Ceftriaxone 62.90%, Ceftazidime 61.30%.Conclusions: Escherichia coli infected more in urinary tract infection as compare to other sample in human, and it is common in female than male. Regular monitoring of antimicrobial susceptibility for E.coli is recommended to improve treatment. A changing trend in antibiotic sensitivity profile of the isolates need to be monitored as there is limited availability of newer drugs and the emergence of resistant bacteria far exceeds the rate of new drug development.

scholarly journals A study on catheter associated urinary tract infections (CAUTI) and antibiotic sensitivity pattern of uropathogens causing CAUTI from a tertiary care hospital

2021 ◽  
Vol 8 (3) ◽  
pp. 196-199
Author(s):  
Archana Rao K ◽  
Vishwajith ◽  
Ritika Sahkare ◽  
Sangeetha S
Keyword(s):  
Urinary Tract ◽  
Infection Control ◽  
Urinary Tract Infections ◽  
Tertiary Care ◽  
Clinical Signs ◽  
Antibiotic Sensitivity ◽  
Urine Samples ◽  
Care Hospital ◽  
Sensitivity Pattern ◽  
Tract Infections

Catheter-associated urinary tract infections (CAUTI), remains the commonest hospital-acquired infection (HAI). This emphasizes the need to implement and monitor effective infection control programs to reduce the risk of CAUTI. Aim of the present study was to determine the etiology with antibiotic susceptibility and also to calculate CAUTI rate. The Patients admitted in intensive care unit (ICU), Rajarajeshwari Medical College and Hospital who were on urinary catheter insertion for >48 hours from 1 August, 2019 to 30 September, 2019 were included in the study. Under aseptic conditions urine samples were collected from clinically suspected cases of CAUTI, the samples were processed in the department of Microbiology, as per standard protocols. Uropathogens were isolated, identified and subjected to antibiotic sensitivity test. CAUTI rate was calculated and results were noted. Among 460 patients on catheter in ICU, 28(6%) patients developed clinical signs or symptoms of UTI. Of 28 urine samples cultured, 4(14%) yielded growth of single organis [Escherichia coli (3), Klebsiella (1)] and 24(86%) showed no evidence of growth. 2300 catheter days were obtained of 460 patients on indwelling catheter in ICU. Thus CAUTI rate was 1.74 per 1000 catheter days over a 2 month period.CAUTI remained a great burden to patient safety and a challenge to the infection control team. Implementation of proper care bundles and continuous education to health care workers plays a key role in reducing the CAUTI rates, thereby decreasing the morbidity and hospital stay to the patients.

scholarly journals Urinary Tract Infection and Antibiotic Susceptibility at Nepalgunj Medical College and Teaching Hospital, Kohalpur

2018 ◽  
Vol 14 (2) ◽  
pp. 34-37
Author(s):  
Binod Mahaseth ◽  
Madhuri Srivastava ◽  
C. R. Das ◽  
Durga Rawat
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Teaching Hospital ◽  
Antibiotic Sensitivity ◽  
Pathogenic Microorganism ◽  
Medical College ◽  
Microbial Profile ◽  
Number Of Patients ◽  
Sensitivity Pattern ◽  
Tract Infections

Introduction: In developing countries, urinary tract infections (UTIs) are one of the most commonly diagnosed diseases among the patient seeking medical service and are treated with empirical antibiotics which does not provides cure and causes resistance.Objective: To find out the incidence of urinary tract infections and antibiotics sensitivity pattern among bacterial pathogens isolated in patients attending Nepalgunj Medical College and Teaching Hospital, Kohalpur.Methodology: All patients (both male and female) were included in the study with the clinical suspicion of UTI . They had their urine culture done. Incidence of UTI and spectrum of pathogens with their sensitivity were recorded.Result: A total number of 1445 patients were clinically suspected for UT. They had their urine cultura and sensitivity done Total number of patients with culture positive was 391(27.05%). The majority of isolates were from female patients comprising of 314(80.3%) patients. The most common pathogenic microorganism isolated was E.coli (73.65%). Second most common organism was Klebsiella (19.9%), it was followed by Acinetobacter (3.5%), Enterobacter (3.06%), Pseudmonas and Proteus (0.76%) each, Staphylococcus (0.05%) salmonella (0.02%). The isolated microorganisms showed maximum sensitivity to Nitrofurantin and Amikacin. The isolated microorganism demonstrated resistance to cefpodoxime and Cefotaxime.Conclusion: Urinary tract infections is a commonly encountered case in general practice Females are more commonly affected than men. The microbial profile and the antibiotic sensitivity pattern must be taken into account while planning for the management. Regular supervision of the sensitivity pattern of pathogenic microorganism is mandatory for effective treatment.JNGMC, Vol. 14 No. 2 December 2016, Page: 34-37

scholarly journals Trend of Sensitivity Pattern of Uropathogenic Escherichia coli: Five Year Experience at a Tertiary Care Hospital in Dhaka

2013 ◽  
Vol 5 (2) ◽  
pp. 103-105
Author(s):  
Most. Fahmida Begum ◽  
Abu Syed Md. Mosaddek ◽  
Kawser Perveen ◽  
Rezina Karim ◽  
Nurun Nahar Begum
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Bacterial Infections ◽  
Tertiary Care ◽  
Care Hospital ◽  
College Hospital ◽  
Medical College ◽  
Sensitivity Pattern ◽  
Study Population ◽  
Tract Infections

Background: Urinary tract infections are among the most common bacterial infections caused by pathogens with a decreasing susceptibility to several classes of antimicrobials.Objective: The purpose of the present study was to see the trend of sensitivity pattern of Escherichia coli (E. coli) isolated from the urinary tract patients.Methodology: This retrospective study was conducted at Uttara Adhunik Medical College Hospital, Dhaka from 2008 to 2012 for a period of 5(five) years. All patients were within ages 1 month to 80 years, comprising of both male and female, either out or in patients were included as study population. Urine sample was collected and Escherichia coli was isolated and identified as well as the antimicrobial susceptibility patterns was determined.Results: A total number of 16,666 urine samples were collected. No significant changes of susceptibility pattern of Escherichia coli was found to ciprofloxacin, cephradine, ceftriaxone, levofloxacin,  nalidixic  acid,  imipenem  and  meropenem;  however,  significant  change  was  detected  to amoxicillin, amoxiclav, cefixime, trimethoprim-sulfamethoxazole, amikacin, ceftazidime and mecillinam between 2008 and 2012.Conclusion: Trend of sensitivity pattern of Escherichia coli is changing to few important antibiotics.DOI: http://dx.doi.org/10.3329/jssmc.v5i2.20766J Shaheed Suhrawardy Med Coll, 2013;5(2):103-105

scholarly journals Antibiotic Sensitivity Pattern of the Isolated of Urinary Pathogens at Dhaka National Medical College & Hospital

2012 ◽  
Vol 18 (1) ◽  
pp. 4-6
Author(s):  
Md Badrul Islam ◽  
Munir Hasan
Keyword(s):  
Urinary Tract ◽  
Antibiotic Sensitivity ◽  
College Hospital ◽  
National Medical College ◽  
Medical College ◽  
National Medical ◽  
Sensitivity Pattern ◽  
Tract Infections ◽  
Common Infection ◽  
Klebsiella Spp

Urinary tract infection is the most common infection causing illness in children and adults. This study was aimed to identify the uropathogens and their antibiotic sensitivity pattern. This study was done in Microbiology Department at Dhaka National Medical College & Hospital, Dhaka, during January, 2010 to December, 2010. A total of 1874 samples of urine were collected from suspected cases of urinary tract infections, from Dhaka National Medical College & Hospital. Among them, 290 (15.48%) showed significant bacterial growth. The most common uropathogens isolated were E.coli 229 (78.97%), Staph. saphrophyticus 15 (5.18%), Coliform 12 (4.13%), Klebsiella spp. 10 (3.44%), Enteococous 10 (3.44%), Staph. aureus 05 (1.72%), Streptococcus spp. 05 (1.72%) and Pseudomonas spp. 04 (1.38%). E.coli is the most common urupathogen and showed sensitivity pattern to Imipenem 84.28%, Amikacin 83.41%, Nitrofurantoin 73.80%, Gentamycin 66.88%, Ciprofloxacin 41.48%, Doxycycline 36.30%, Ceftazidime 34.50%, Ceftriaxone 33.62%, Cefexime 31.0%, Cotrimoxazole 32.31%, Nalidixic acid 24.01%, Cephradine 17.47% and Ampicillin 11.35%. DOI: http://dx.doi.org/10.3329/jdnmch.v18i1.12223 J. Dhaka National Med. Coll. Hos. 2012; 18 (01): 4-6

Viability and survival capability of quinolone-resistant uropathogenic Escherichia coli

2010 ◽  
Vol 5 (6) ◽  
pp. 827-830
Author(s):  
Georgi Slavchev ◽  
Nadya Markova
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Expression System ◽  
Antibiotic Sensitivity ◽  
Uropathogenic Escherichia Coli ◽  
Resistant Bacteria ◽  
E Coli ◽  
Serum Bactericidal Assay ◽  
Tract Infections ◽  
Macrophage Killing

AbstractUropathogenic strains of E. coli isolated from urine of patients with urinary tract infections were tested for antibiotic sensitivity using bio-Merieux kits and ATB-UR 5 expression system. The virulence of strains was evaluated by serum bactericidal assay, macrophage “killing” and bacterial adhesive tests. Survival capability of strains was assessed under starvation in saline. The results showed that quinolone-resistant uropathogenic strains of E. coli exhibit significantly reduced adhesive potential but relatively high resistance to serum and macrophage bactericidity. In contrast to laboratory strains, the quinolone-resistant uropathogenic clinical isolate demonstrated increased viability during starvation in saline. Our study suggests that quinolone-resistant uropathogenic strains are highly adaptable clones of E. coli, which can exhibit compensatory viability potential under unfavorable conditions. The clinical occurrence of such phenotypes is likely to contribute to the survival, persistence and spread strategy of resistant bacteria.

scholarly journals Determination of nitrofurantoin and fosfomycin susceptibility among urinary Escherichia coli isolates

2020 ◽  
Vol 8 (9) ◽  
pp. 3274
Author(s):  
Rachana Kanaujia ◽  
Amit Kumar ◽  
Malay Bajpai
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Urine Samples ◽  
E Coli ◽  
Tract Infections ◽  
Therapeutic Alternatives ◽  
Micro Organisms ◽  
Staphylococcus Spp

Background: Urinary tract infections (UTIs) are one of the most common infections. For treatment of UTIs, there are limited antibiotics due to increased resistance among uropathogens. Two older antibiotics; Nitrofurantoin and Fosfomycin have become novel oral therapeutic options against uropathogens. Aim of the study was to identify UTI causing micro-organisms and evaluate in-vitro activity of nitrofurantoin and fosfomycin against most common isolated organism (E. coli).Methods: Results of urine samples culture and susceptibility testing over a period of 1 year were analysed and included in this study.Results: Micro-organisms were isolated from 568 urine samples. Most commonly isolated organism was Escherichia coli (40.50%), followed by Klebsiella spp. (20.07%) and Staphylococcus spp. (17.07%). Susceptibility of E. coli to nitrofurantoin and fosfomycin was 91.74% and 65.65% respectively. Conclusion: Good activity of nitrofurantoin and fosfomycin against E. coli indicates that these two drugs are potential therapeutic alternatives for urinary tract infections.

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