scholarly journals Antimicrobial Sensitivity Pattern of the isolated Uropathogens at a Teaching Hospital

2020 ◽  
Vol 17 (2) ◽  
pp. 42-45
Author(s):  
Md. Badrul Islam ◽  
Md. Abdullah Yusuf ◽  
Munir Hassan ◽  
Shimul Akter

Background: Urinary tract infection is the most common infection occurs in both male and female. Objective: This study was aimed to identify the uropathogens and their antimicrobial sensitivity pattern. Methodology: This study was carried out in the Department of Microbiology at Dhaka National Medical College & Hospital, Dhaka from January 2018 to December 2018. Result: A total of 1686 samples of urine were collected from suspected cases of urinary tract infections from Dhaka National Medical College & Hospital. Among them, 292 (17.32%) specimens showed significant bacterial growth. The most common uropathogens isolated were Escherichia coli. Conclusion: In conclusion Gram negative bacteria is the commonest uropathogens isolated. Journal of Science Foundation July 2019;17(2):42-45

2012 ◽  
Vol 18 (1) ◽  
pp. 4-6
Author(s):  
Md Badrul Islam ◽  
Munir Hasan

Urinary tract infection is the most common infection causing illness in children and adults. This study was aimed to identify the uropathogens and their antibiotic sensitivity pattern. This study was done in Microbiology Department at Dhaka National Medical College & Hospital, Dhaka, during January, 2010 to December, 2010. A total of 1874 samples of urine were collected from suspected cases of urinary tract infections, from Dhaka National Medical College & Hospital. Among them, 290 (15.48%) showed significant bacterial growth. The most common uropathogens isolated were E.coli 229 (78.97%), Staph. saphrophyticus 15 (5.18%), Coliform 12 (4.13%), Klebsiella spp. 10 (3.44%), Enteococous 10 (3.44%), Staph. aureus 05 (1.72%), Streptococcus spp. 05 (1.72%) and Pseudomonas spp. 04 (1.38%). E.coli is the most common urupathogen and showed sensitivity pattern to Imipenem 84.28%, Amikacin 83.41%, Nitrofurantoin 73.80%, Gentamycin 66.88%, Ciprofloxacin 41.48%, Doxycycline 36.30%, Ceftazidime 34.50%, Ceftriaxone 33.62%, Cefexime 31.0%, Cotrimoxazole 32.31%, Nalidixic acid 24.01%, Cephradine 17.47% and Ampicillin 11.35%. DOI: http://dx.doi.org/10.3329/jdnmch.v18i1.12223 J. Dhaka National Med. Coll. Hos. 2012; 18 (01): 4-6


2012 ◽  
Vol 17 (1) ◽  
pp. 18-21 ◽  
Author(s):  
Belal Ahmed ◽  
Prof Wanaiza ◽  
Mursheda Akhter ◽  
Munir Hasan ◽  
Md Khorshed Alam

Urinary tract infections (UTIs) are some of the most common infections experienced by human. It is also the most common cause of nosocomial infections in adults. The aim of this study was to determine the bacteriological pattern and their sensitivity to commonly used antimicrobial drugs in urinary tract infection in Bangladesh. This was a prospective study conducted in Microbiology department of Dhaka National Medical College, a tertiary level teaching hospital in Dhaka, Bangladesh. A total of 216 culture positive urine samples were examined. Female patient were found to be more 65.7% than male 34.3%. Maximum patients were from 20-35 yrs. age group. The most common isolate was E.coli 84.3%. These E.coli is more sensitive to Imipenem 93.98%, Amikacin 90.52%, Nitrofurantoin 78.88% Ceftazidim 78.26%, Ciprofloxacin 70.67%, Cefuroxime 65.49%,Ofloxacin 60.83%, Ceftriaxone 59.03% and Cephradin 56.96%. Resistance is more in case of amoxicillin 82.41%, Doxycycline 72.42%, Cefixime 58.70% and Nalidixic Acid 57.02%. DOI: http://dx.doi.org/10.3329/jdnmch.v17i1.12186 J. Dhaka National Med. Coll. Hos. 2011; 17 (01): 18-21


Med Phoenix ◽  
2020 ◽  
Vol 5 (1) ◽  
pp. 40-45
Author(s):  
Sagar Ghimire ◽  
Sanjay Paudel ◽  
Shahrukh KC ◽  
Pragya Gautam ◽  
Vikash Paudel

Background: Urinary tract infections (UTIs) are one of the most common infectious conditions seeking treatment. There are varieties of microorganisms associated. The bacteriological investigations are incomplete without antibiotic sensitivity test of the isolate. Our aim is to determine age and sex distribution of UTI, bacteriological profile, and antibiotic sensitivity pattern of the organisms. Materials and Methods: A retrospective cross-sectional observational study of records of patients with clinically suspected UTI from Kartik 2076 to Magh 2076 was conducted at National Medical College and Teaching Hospital (NMCTH). It included both inpatient and OPD visit patients who submitted their clean-catch midstream urine sample for culture and antibiotic sensitivity at Microbiology lab of NMCTH. Result: Out of 385 patients, 103 (26.75%) showed bacterial growth. Escherichia coli (47.58 %) was the most common organism followed by Staphylococcus sps. (18.45%) and Klebsiella sps.(17.47%) respectively. There was female dominance (62.13%) but male were predominantly affected in children and older population. The most common age group for UTI was 21-30 years (mean age 25 years) and females were more affected than males. The most common pathogen was Escherichia coli, followed by Staphylococcal sps. and Klebsiella. All the organisms showed best sensitivity to tigecycline (100%). Conclusion: This study highlights the common pathogens causing UTI and their antibiotic sensitivity patterns which could help clinicians in starting rational empirical antibiotic therapy for such patients while awaiting urine culture reports.   


2017 ◽  
Vol 2 (1) ◽  
pp. 134-137 ◽  
Author(s):  
Binita Pradhan ◽  
SB Pradhan

IntroductionIn developing countries, urinary tract infections (UTIs) are one of the most commonly diagnosed diseases among the patient seeking medical service and being treated with empirical antibiotics which causes resistance.ObjectiveTo find out the prevalence of urinary tract infection and sensitivity pattern of antibiotics among bacterial pathogens isolated in patients attending Kathmandu Medical College Teaching Hospital, Duwakot.MethodologyAll the patients with the clinical suspicion of UTI were sent for urine culture. Prevalence of UTI and urinary pathogens isolated with antimicrobial profile was correlated.ResultA total number of 1735 clinically suspected as UTI cases were sent for urine culture sensitivity. Total culture positive were 239 (13.8%). The majority of isolates were from female patients comprising 180 (75%). The most common pathogenic microorganism isolated was E.coli (79.1%). Second most common organism was Klebsiella (11.7%) followed by Citrobacter (3.34%) and Proteus (2.92%). The isolated microorganism showed maximum number of sensitivity with the antibiotics Ofloxacin and Ciprofloxacin. The isolated microorganism demonstrated resistance with Nalidixic Acid and Co-Trimoxazole. ConclusionUrinary tract infection is a commonly encountered case in general practice. Females are commonly affected than men. The microbiological profile and the antibiotic sensitivity pattern while initiating empirical treatment must be taken into account while planning for the management. Regular supervision of the sensitivity pattern of pathogenic microorganism is mandatory for effective treatment.Birat Journal of Health Sciences Vol.2/No.1/Issue 2/ Jan - April 2017, Page: 134-137


Author(s):  
Nikhil S. Yadav ◽  
Swanand S. Pathak

Background: Urinary tract infections are commonly seen in febrile children, high incidence of Vesico Ureteral Reflux (VUR) is frequently seen in paediatric patient which is of concern as it may lead to renal scarring. Despite presence of established clinical guidelines there is disparity amongst physician in the diagnosis and treatment of UTI, some physician prescribes taking into consideration the symptoms, some prescribe on the basis of smell and colour and some rely on urine culture and sensitivity report. There is dearth of studies in many tertiary health care centers regarding antimicrobial use. Authors conducted this study to evaluate antimicrobial sensitivity pattern, efficacy and cost effectiveness of antimicrobials used for UTI in children.Methods: Patients of urinary tract infection <13 years of age were included in the study. Symptoms of patient i.e. pain in abdomen, haematuria, increased frequency of urination and degree of fever were recorded. Efficacy was measured through calculating degree of defervescence per hour. Cost effective model was prepared by calculating cost effective ratio i.e. dividing cost of antimicrobial required to bring down the fever and degree through which fever came down.Results: E. coli was the most common pathogen isolated from urine positive culture (69.07%). Nitrofurantoin has shown highest sensitivity to all uropathogens (72.73%). Cotrimoxazole, ciprofloxacin and nitrofurantoin were found to be most cost effective.Conclusions: In this current study authors found E coli is the most common uropathogen isolated. Ceftriaxone, cefixime, cotrimoxazole and amikacin were found to be most efficacious. Cotrimoxazole, ciprofloxacin and nitrofurantoin were found to be most cost effective.


2018 ◽  
Vol 5 (11) ◽  
pp. 3527
Author(s):  
Prabhubhai R. Tandel ◽  
Himanshu R. Patel ◽  
Kiran U. Patel

Background: The urinary tract obstruction occurs due to several causes. one of the most important cause of obstruction is urinary calculus. urinary calculi are the third most common affliction of the urinary tract exceeded only by urinary tract infection and pathology of prostate. Improvement of the medical facility and increased health consciousness has resulted in more patients presenting with early urinary tract obstruction due stone.Methods: This is prospective study. It was conducted from July 2017 to August 2018 at GMERS medical college Valsad. A Study of 50 cases was carried out, after thorough clinical examination and necessary investigations, patients were subjected to x ray KUB, ultrasonography, intravenous pyelography. The samples were cultured & Antimicrobial sensitivity determined.Results: Escherichia coli is the commonest urinary pathogen causing 60 -90 % of infection, but in this study 72% of patient came infected with Escherichia coli 16% came infected with Klebsiella. Infection of anterior urinary tract (Urethritis) is mainly caused by N. Gonrrhoeae, staphylococci and chlamydia. Gentamicin is found to be most effective drug (78% sensitivity) in present series this is followed by Gatifloxacin (60% sensitivity), Septran (36% sensitivity) & Cefotaxime (34% sensitivity).Conclusions: It is concluded that most of the urinary tract infections in human are caused by Escherichia coli with more sensitivity to Gentamicin.


2019 ◽  
Vol 5 (2) ◽  
pp. 61-64
Author(s):  
Md Badrul Islam ◽  
Md Abdullah Yusuf ◽  
Samia Afrin ◽  
Md Abul Bashar

Objectives: This study was carried out to detect extended spectrum B-lactamases (ESBLs) among Gram negative bacteria isolated from hospitalized patients and community patients (OPD) by double disc synergy test and phenotypic confirmatory test. Methodology: This cross-sectional, prospective study was carried out in the Department of Microbiology. Dhaka National Medical College, over a period of 1 (one) year 2016. Urine samples were collected from patients. Urine samples were from hospitalized patients and community patients. Samples were collected from in-patient and outpatient department of Dhaka National Medical College Hospital having clinical symptoms of microbial infection. Samples were collected from both sexes and different age groups. Result: Total 220 urine samples were collected from suspected cases of urinary tract infection. Total 132 (60%) Gram negative bacteria were isolated from these patients as causative agents. Among the isolates, 88 (75.86%) in hospitalized patients and 44 (42.31%) in community patients were isolated. Out of 132 Gram negative bacteria, 31 (23.48%) were ESBL producers. The percentage of ESBL producing bacteria was (31.81%) in hospitalized patients and (6.82%) in community patients. Conclusion: In the present study, it was observed that considerable numbers of ESBL producing bacteria were detected from urinary tract infection cases. These cases indicate ESBLs will be major threat for antibiotic therapy. Bangladesh Journal of Infectious Diseases, December 2018;5(2):61-64


2011 ◽  
Vol 5 (1) ◽  
pp. 21-25 ◽  
Author(s):  
Sanya Tahmina Jhora ◽  
Shikha Paul

The present study was conducted to observe the antibiotic sensitivity pattern of isolated S. saprophyticus from urine samples of patients admitted in inpatient department or visited the out patient department of Sir Salimullah Medical College & Mitford Hospital (SSMC& MH) Dhaka from October 2002 to September 2003. Among the isolates, Esch.coli was the most predominant (82.61%) urinary pathogens followed by S. saprophyticus (7.01%). 93.10% S.saprophyticus was isolated from females of which highest (44.82%) rate of isolation was among female of 18- 45 years age group. Rate of isolation was also high (41.38%) among female of <18 years age group. All strains of S.saprophyticus (100%) were sensitive to Imipenem. High sensitivity was also observed to gentamicin (86.20%) andceftriaxone (72.41%). Ciprofloxacin was found to be sensitive against 68.96% isolates. Sensitivity of ceftazidime, cephalexin and cloxacillin were 65.51%, 55.17% and 55.17% respectively. However, most of the S. saprophyticus are resistant to ampicillin, nalidixic acid and cotrimoxazole. So, the present study illustrates that physicians and microbiologists must be aware that S. saprophyticus is an important cause of UTIs in young women and there is a need for continuous evaluation of common antibiotics used in the therapy of uropathogens.DOI: http://dx.doi.org/10.3329/bjmm.v5i1.15817 Bangladesh J Med Microbiol 2011; 05 (01): 21-25


2019 ◽  
Vol 3 (1) ◽  
pp. 21-23 ◽  
Author(s):  
Prakash Sah ◽  
Komal Raj Rijal ◽  
Bikash Shakya ◽  
Bishnu Raj Tiwari ◽  
Prakash Ghimire

Nasal carriage of S. aureus has been identified as a risk factor for community-acquired and nosocomial infections. Healthyhospital personnel may carry pathogenic hospital strains in their nose and skin and may spread these pathogens to thecommunity leading to more dreadful condition. This study was carried out at National Medical College & Teaching Hospitalwith the objective to study the nasal carriage of Staphylococcus aurues among the staffs at the hospital. A total of 54 nasalswabs were taken from the hospital staff. All the samples were processed following standard microbiological method. Grampositive cocci that were mannitol fermenting, catalase positive and coagulase positive isolates were considered as S. aureus.Nasal carriage rate of S. aureus among hospital staff was found to be 20.37%. Carriage among male and female staff was19% and 21.2% respectively (p>0.05). All nasal S. aureus isolates were sensitive to Amikacin and Vancomycin. Methicillinresistance rate was found to be 45.5%. High rate of nasal carriage of S. aureus indicates need for standard infection controlpractices to prevent transmission. Key words: Hospital staff, Nasal Carriage, S. aureus


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