scholarly journals Profile of Patients with Stroke in Western Region of Nepal: A Hospital based Retrospective Study

2020 ◽  
Vol 3 (1) ◽  
pp. 239-243
Author(s):  
Buddhi Sagar Lamichhane ◽  
Surya Bahadur Hamal Thakuri ◽  
Rabi Mohan Dhakal ◽  
Tulsi Dhakal ◽  
Gopal Khanal

Background: Stroke is one of the most common cause of morbidity and mortality worldwide. Approximately 50-85 percent of strokes are due to ischemic cerebral infarction and 7-27 percent to intracerebral hemorrhage. Since the incidence of stroke is increasing in our country, the study aims to identify various factors associated with stroke. Materials and Methods: This is a retrospective study of 86 patients admitted in A & B International Hospital, which is a private hospital located in Pokhara ,Nepal from 1st January 2018 to 31st December 2019.The case notes were taken from hospital record section and relevant data extracted and analyzed. Approval from the hospital management was taken prior to collecting the case notes. Patients below 18 years of age, stroke due to trauma were excluded. The data were collected, and were analyzed using SPSS version 20.0 software Results: Of the total 86 patients studied, the age range was from 36 years to 94 years with mean age of 64.3 years. Mean age in ischemic stroke was 66.7 years and in hemorrhagic stroke was 54.8 years. Stroke is more common in men than female (2.3:1 ratio) .Ischemic stroke accounted for 80.2 percent of cases and hemorrhagic stroke for 19.2 percent. Most common presentation included limb weakness, facial deviation and speech abnormality. Most common vascular territory involved was MCA territory infarction and small vessel strokes. Conclusion: Stroke is prevalent in our country and the incidence rises with age. Ischemic stroke is more prevalent than hemorrhagic stroke. Mean age of hemorrhagic stroke is lower than that of ischemic stroke and hypertension is most commonly associated risk factor for both types of stroke.

2020 ◽  
Vol 1 (2) ◽  
Author(s):  
Jeremia A. Tombeng ◽  
Corry N. Mahama ◽  
Mieke A. H. M. Kembuan

Abstract: Stroke is the most common cause of seizures in elderly population. The higher the number of stroke patients, the higher the predicted level of likelihood of the prevalence of post-stroke seizures. This study was aimed to obtain the profile of post-stroke seizures among hospitalized patients from July 2018 to June 2019 at Prof. Dr. R. D. Kandou Hospital Manado. This was a descriptive and retrospective study. The results showed 24 patients who met the inclusion criteria. Post-stroke seizures were more common in males than in females. Based on age, most patients with post-stroke seizures were in the age range of 45-54 years. Many post-stroke seizure patients worked as housewives. Most post-stroke seizure patients suffered from focal seizures with impaired awareness. Among patients with post-stroke seizures, the number of patients with ischemic stroke type was higher than of patients with hemorrhagic stroke type. In conclusion, the majority of patients were males, aged 45-54 years, had focal seizures and impaired awareness, as well as ischemic stroke. The most common job of the patients was housewifery.Keywords: stroke, seizures, post-stroke seizures Abstrak: Stroke merupakan penyebab kejang yang paling umum pada populasi lansia. Semakin tinggi data yang menunjukkan jumlah pasien stroke, maka tingkat kemungkinan prevalensi terjadinya kejang pasca stroke juga diprediksi akan meningkat. Penelitian ini bertujuan untuk mengetahui profil kejang pasca stroke pada pasien rawat inap periode Juli 2018-Juni 2019 di RSUP Prof. Dr. R. D. Kandou Manado. Jenis penelitian ialah deskriptif retrospektif. Hasil penelitian memperoleh 24 pasien yang memenuhi kriteria inklusi. Jumlah pasien kejang pasca stroke lebih banyak pada laki-laki dibandingkan perempuan. Berdasarkan usia pasien kejang pasca stroke terbanyak berada dalam rentang usia 45-54 tahun. Berdasarkan pekerjaan, pasien kejang pasca stroke terbanyak bekerja sebagai ibu rumah tangga. Sebagian besar pasien kejang pasca stroke mengalami kejang fokal dengan kesadaran terganggu. Jumlah pasien kejang pasca stroke dengan tipe stroke iskemik lebih banyak dibandingkan tipe stroke hemoragik. Simpulan penelitian ini ialah mayoritas pasien dengan kejang pasca stroke berjenis kelamin laki-laki, berusia 45-54 tahun, tipe kejang fokal dengan kesadaran terganggu, dan tipe stroke iskemik. Pekerjaan yang terbanyak didapatkan ialah ibu rumah tangga.Kata kunci: stroke, kejang pasca stroke


2018 ◽  
Vol 14 (2) ◽  
pp. 53-55
Author(s):  
Sanjib Kumar Shah ◽  
Sunil Shah ◽  
Sujeet Kumar Shah ◽  
Shyam B.K.

 Background: Stroke is the major public health burden and the second major cause of death worldwide. This disease is common in old age persons, however the disease can also be seen in young persons. Identifying the modifiable risk factors of stroke may have contribution in prevention.Objective: The retrospective study was done to study risk factors of stroke in adult patients.Method and Material: This is a hospital based retrospective study conducted in Department of Medicine, Nepalgunj Medical College and st th Teaching Hospital, Kohalpur from the period of 1 January 2015 to 30 October 2016. A total of 119 patients were involved in this study. The diagnosis was confirmed using CT scan after taking history and performing clinical examination. Patients were then evaluated for the presence of both non-modifiable as well as modifiable risk factors. The data analysis was done using SPSS 13.0.Results: The mean age of the patient was 59.76±11.22. Among the collected patients, the higher percentage were male in comparison to female. Ischemic Stroke was more common than hemorrhagic stroke in our study. Other conventional risk factors were as follows: Alcohol use75(63%),cigarette smoking 70(58.8%), hypertension 60 (50.4%),diabetes 11(9.2%),previous vascular event 9(7.6%), heart disease 4(3.4%).Conclusions: Ischemic stroke was more common than hemorrhagic stroke; with alcohol use followed by smoking, hypertension and diabetes mellitus being the most common modifiable risk factors. Incidence of stroke increases with the age and the early recognition and management of the risk factors might reduce this major public burden. JNGMC,  Vol. 14 No. 2 December 2016, Page: 53-55


2021 ◽  
Vol 12 ◽  
Author(s):  
Bum Joon Kim ◽  
Yang-Ha Hwang ◽  
Man-Seok Park ◽  
Joon-Tae Kim ◽  
Kang-Ho Choi ◽  
...  

Background: Ischemic stroke with atrial fibrillation (AF) may recur despite appropriate treatment. It may be AF-related or AF-unrelated. We compared the factors associated with AF-related and AF-unrelated recurrences among ischemic stroke patients with AF.Methods: Patients with ischemic stroke and AF were enrolled from 11 centers in Korea. Ischemic stroke recurrence was classified as AF-related if the lesion pattern was compatible with cardioembolism without significant stenosis or as AF-unrelated if the lesion was more likely due to small vessel disease or arterial stenosis. Factors associated with stroke recurrence (AF-related and AF-unrelated) were investigated.Results: Among the 2,239 patients, 115 (5.1%) experienced recurrence (75 AF-related and 40 AF-unrelated). Factors independently associated with any stroke recurrence included AF diagnosed before stroke, small subcortical infarctions, and small scattered lesions in a single vascular territory. Type of AF was associated with the type of stroke recurrence, with persistent AF being associated with AF-related stroke [hazard ratio (HR) = 2.94, 95% confidence interval (CI) 1.69–5.26; p < 0.001]. By contrast, paroxysmal AF (HR = 3.76, 95% CI 1.56–9.04; p = 0.003), AF diagnosed before stroke (HR = 2.38, 95% CI 1.19–4.55; p = 0.014), small scattered lesions in a single vascular territory (reference: corticosubcortical lesion, HR = 3.19, 95% CI 1.18–8.63; p = 0.022), and the use of antiplatelet agents (HR = 2.11, 95% CI 1.11–4.03; p = 0.024) were independently associated with AF-unrelated stroke.Conclusion: Persistent AF was more associated with AF-related stroke recurrence, whereas paroxysmal AF was more associated with AF-unrelated stroke recurrence. A scattered lesion in a single vascular territory may predict AF-unrelated stroke recurrence.


2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Alcivan Batista de Morais Filho ◽  
Thiago Luis de Holanda Rego ◽  
Letícia de Lima Mendonça ◽  
Sulyanne Saraiva de Almeida ◽  
Mariana Lima da Nóbrega ◽  
...  

Abstract Hemorrhagic stroke (HS) is a major cause of death and disability worldwide, despite being less common, it presents more aggressively and leads to more severe sequelae than ischemic stroke. There are two types of HS: Intracerebral Hemorrhage (ICH) and Subarachnoid Hemorrhage (SAH), differing not only in the site of bleeding, but also in the mechanisms responsible for acute and subacute symptoms. This is a systematic review of databases in search of works of the last five years relating to the comprehension of both kinds of HS. Sixty two articles composed the direct findings of the recent literature and were further characterized to construct the pathophysiology in the order of events. The road to the understanding of the spontaneous HS pathophysiology is far from complete. Our findings show specific and individual results relating to the natural history of the disease of ICH and SAH, presenting common and different risk factors, distinct and similar clinical manifestations at onset or later days to weeks, and possible complications for both.


Author(s):  
Pushpinder S. Khera ◽  
Pawan K. Garg ◽  
Sarbesh Tiwari ◽  
Narendra Bhargava ◽  
Taruna Yadav ◽  
...  

Abstract Introduction Retrograde transvenous obliteration (RTO) with the assistance of a balloon (BRTO) or a vascular plug (PARTO) is an established method for treating gastric varices (GVs) secondary to portal hypertension. Most of the available studies on RTO have used lipiodol along with sclerosing agents like ethanolamine oleate or sodium tetradecyl sulfate (STS). We evaluated the safety and efficacy of RTO for treating GVs using STS as a sclerosant without lipiodol. Materials and Methods Sixteen patients (nine men, age range 16–74 years) were included in this retrospective study. Twelve patients presented with acute bleeding, two with chronic bleeding, one with large varices without bleeding, and one with refractory hepatic encephalopathy (HE). BRTO was attempted in 14 patients and PARTO in 2 patients. The technical and clinical success and complications of RTO were studied. Results The RTO procedure was technically successful in 14 (14/16, 87.5%) patients, with 13 (13/14, 93%) obtaining clinical success. One patient died due to the early recurrence of bleeding. Three patients had minor intraprocedural complications. Conclusion Retrograde gastric variceal obliteration using STS is safe and technically feasible with high technical and clinical success and low complication rate.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hai-fei Jiang ◽  
Yi-qun Zhang ◽  
Jiang-xia Pang ◽  
Pei-ning Shao ◽  
Han-cheng Qiu ◽  
...  

AbstractThe prominent vessel sign (PVS) on susceptibility-weighted imaging (SWI) is not displayed in all cases of acute ischemia. We aimed to investigate the factors associated with the presence of PVS in stroke patients. Consecutive ischemic stroke patients admitted within 24 h from symptom onset underwent emergency multimodal MRI at admission. Associated factors for the presence of PVS were analyzed using univariate analyses and multivariable logistic regression analyses. A total of 218 patients were enrolled. The occurrence rate of PVS was 55.5%. Univariate analyses showed significant differences between PVS-positive group and PVS-negative group in age, history of coronary heart disease, baseline NIHSS scores, total cholesterol, hemoglobin, anterior circulation infarct, large vessel occlusion, and cardioembolism. Multivariable logistic regression analyses revealed that the independent factors associated with PVS were anterior circulation infarct (odds ratio [OR] 13.7; 95% confidence interval [CI] 3.5–53.3), large vessel occlusion (OR 123.3; 95% CI 33.7–451.5), and cardioembolism (OR 5.6; 95% CI 2.1–15.3). Anterior circulation infarct, large vessel occlusion, and cardioembolism are independently associated with the presence of PVS on SWI.


Author(s):  
Brystana G. Kaufman ◽  
Nirosha Mahendraratnam ◽  
Thuy-vi Nguyen ◽  
Laura Benzing ◽  
Jessica Beliveau ◽  
...  

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Chun-Hsiang Lin ◽  
Oswald Ndi Nfor ◽  
Chien-Chang Ho ◽  
Shu-Yi Hsu ◽  
Disline Manli Tantoh ◽  
...  

Abstract Background Alcohol consumption is one of the modifiable risk factors for intracerebral hemorrhage, which accounts for approximately 10–20% of all strokes worldwide. We evaluated the association of stroke with genetic polymorphisms in the alcohol metabolizing genes, alcohol dehydrogenase 1B (ADH1B, rs1229984) and aldehyde dehydrogenase 2 (ALDH2, rs671) genes based on alcohol consumption. Methods Data were available for 19,500 Taiwan Biobank (TWB) participants. We used logistic regression models to test for associations between genetic variants and stroke. Overall, there were 890 individuals with ischemic stroke, 70 with hemorrhagic stroke, and 16,837 control individuals. Participants with ischemic but not hemorrhagic stroke were older than their control individuals (mean  ±  SE, 58.47 ± 8.17 vs. 48.33 ± 10.90 years, p  <  0.0001). ALDH2 rs671 was not associated with either hemorrhagic or ischemic stroke among alcohol drinkers. However, the risk of developing hemorrhagic stroke was significantly higher among ADH1B rs1229984 TC  +  CC individuals who drank alcohol (odds ratio (OR), 4.85; 95% confidence interval (CI) 1.92–12.21). We found that the test for interaction was significant for alcohol exposure and rs1229984 genotypes (p for interaction  =  0.016). Stratification by alcohol exposure and ADH1B rs1229984 genotypes showed that the risk of developing hemorrhagic stroke remained significantly higher among alcohol drinkers with TC  +  CC genotype relative to those with the TT genotype (OR, 4.43, 95% CI 1.19–16.52). Conclusions Our study suggests that the ADH1B rs1229984 TC  +  CC genotype and alcohol exposure of at least 150 ml/week may increase the risk of developing hemorrhagic stroke among Taiwanese adults.


Sign in / Sign up

Export Citation Format

Share Document