scholarly journals Histomorphological Spectrum of Ovarian Masses in a Tertiary Centre of Eastern Nepal

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Oshan Shrestha ◽  
Reetu Baral ◽  
Shipra Shrestha
Keyword(s):  
Germ Cell Tumors ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Tertiary Centre ◽  
Neoplastic Lesions ◽  
Malignant Lesions ◽  
Serous Tumors ◽  
Sex Cord Stromal Tumors ◽  
Ovarian Masses

Aims: To analyze the trends of ovarian masses in a tertiary centre in eastern Nepal. Methods: This was a retrospective cross sectional study conducted in Department of Pathology at Nobel Medical College and teaching hospital, Biratnagar, Nepal. Database of two years from April 2019 to April 2021 was searched. Gross and microscopic findings of cases including demographic details of patients with ovarian mass were analyzed and presented by descriptive parameters. Results: Out of 127 cases of ovarian masses studied, 95 (74.8%) were neoplastic. The common types were Germ cell tumors were (47; 37%), epithelial tumors (43; 33.9%) and endometriotic cyst (23; 18.1%). Mean age was 38.1 (range: 17-77) years in benign, 47.1 (30 – 70) years in malignant and 36.9 (21-53) years in non-neoplastic tumors; 11 cases were malignant and 63.6% were solid; and 23.8% of serous tumors were bilateral. Conclusions: Benign neoplastic lesions were the most common lesions and presented earlier than borderline and malignant lesions. Endometriotic cysts comprised the most common non- neoplastic lesions. The non-neoplastic lesions were predominantly cystic and the malignant lesions were predominantly solid. Most of the benign lesions were solid-cystic. Most mucinous tumors and all the sex-cord stromal tumors were unilateral while the seromucinous tumor and a significant number of serous tumors were bilateral.

scholarly journals The prevalence of Diabetic Retinopathy in a Tertiary Centre in Western Region, Nepal

2020 ◽  
Vol 13 (2) ◽  
pp. 140-143
Author(s):  
Chandra Bahadur Pun ◽  
Sarita Tuladhar ◽  
Tirtha Lal Upadhyaya ◽  
Jamuna Gurung ◽  
Durga Dhungana
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Cross Sectional Study ◽  
Study Data ◽  
Diabetic Patients ◽  
Multisystem Disease ◽  
Cross Sectional ◽  
Medical College ◽  
Tertiary Centre ◽  
Diabetes Retinopathy

Background: Diabetes mellitus is a multisystem disease. It has multiple complications like retinopathy, neuropathy, nephropathy, diabetes ketoacidosis, and stroke. Diabetes retinopathy (DR) is one of the blinding complications of diabetes. This study was done to find out the prevalence of diabetic retinopathy among diabetic patients attending in the outpatient department (OPD) of internal medicine, Gandaki Medical College and Teaching Hospital (GMCTHRC), Pokhara, Nepal. Materials and Methods: A hospital based cross-sectional study was performed among the 200 diabetes mellitus patients attending in the medicine OPD from 15th December 2017 to 15thDecember 2018. They were referred to eye OPD of GMC. The detailed eye examination including fundus evaluation under mydriasis was done to all the patients. The diagnosis of DR was graded using the Early Treatment Diabetic Retinopathy Study classification (ETDRS). Patients having hypertension and other retinal diseases were excluded from the study. Data analysis was done using statistical package for social sciences (SPPS) version 11.20. Results: The mean age of the patients was 63.02 ±11.8 years. In our study 60.5% of the patients were male and 39.5% were female. Diabetes retinopathy was seen in 29.5% patients, of which non proliferative diabetes retinopathy (NPDR) was present in 19.5%, proliferative diabetes retinopathy (PDR) in 9.5% and 0.5% had diabetes maculopathy. Conclusion: The prevalence of DR is quite significant in the people with diabetes. Early diagnosis and management of retinopathy will help to avoid blindness due to the diabetic retinopathy.  

scholarly journals CLINICOPATHOLOGICAL CORRELATION OF OVARIAN TUMORS IN DARBHANGA MEDICAL COLLEGE AND HOSPITAL, LAHERIASARAI, BIHAR

2020 ◽  
pp. 52-55
Author(s):  
Megha Jha ◽  
Hari Shankar Mishra ◽  
Ajit Kumar Chaudhary ◽  
Debarshi Jana
Keyword(s):  
Germ Cell Tumors ◽  
Disease Process ◽  
Serous Cystadenoma ◽  
Ovarian Tumors ◽  
Histopathological Study ◽  
Histopathological Diagnosis ◽  
Medical College ◽  
Serous Cystadenocarcinoma ◽  
Malignant Lesions ◽  
Sex Cord Stromal Tumors

Introduction and Objective: Ovary is one of the complex organs in terms of its embryology, histology, steroidogenesis and tumor incidence. The present study highlights the correlation between the clinical and pathological features of neoplastic lesions of ovary in order to arrive at a better understanding of the disease process. The objective of study is to assess the overall incidence of various histological types of ovarian neoplasm, the pattern of occurrence of ovarian tumors in relation to age, parity and modes of presentations and to study the histopathological findings of various ovarian tumors. Materials and Methods: Biopsies received at the Department of Pathology, Darbhanga Medical College and Hospital, Laheriasarai, Biharwere subjected for histopathological study. Specimens were then fixed in 10% formalin for 24-48 hour, processed and embedded in paraffin blocks. Sections of 4-6 microns thickness were taken and stained with routine haematoxylin and eosin and studied. IHC was done whenever necessary. Result: Out of 92 cases of ovarian tumors 68 cases were benign, 3 were borderline and 21 were malignant. Serous cystadenoma formed the majority (38%) among benign lesions and among malignant lesions serous cystadenocarcinoma (5.4%) were common. Majority were surface epithelial tumors and constituted 64.13% (59 cases) with germ cell tumors 26% (24 cases) and sex cord stromal tumors 8.6% (8 cases). Conclusion: The correct histopathological diagnosis of ovarian tumor is of prime importance in view of their behavioural predictability, clinical correlation and the proper management of patient.

scholarly journals Spectrum of Exfoliative Cytology at Birat Medical College and Teaching Hospital

2019 ◽  
Vol 4 (2) ◽  
pp. 734-737
Author(s):  
Shilpi Shaukin ◽  
Satosh U Kafle ◽  
Mrinalini Singh
Keyword(s):  
Teaching Hospital ◽  
College Teaching ◽  
Cost Effective ◽  
Cross Sectional Study ◽  
Exfoliative Cytology ◽  
Cross Sectional ◽  
Medical College ◽  
Important Diagnostic Tool ◽  
Breast Fluid ◽  
Malignant Lesions

Introduction: Exfoliative cytological study of body fluids is easy, simple, rapid, cost effective and patient compliant investigation that helps in characterizing the disease into their varying subtypes. These presumptive and sometimes definitive diagnoses are in most cases the cornerstone which helps in staging and prognosis of the patient Objective: To determine the spectrum of malignant and non-malignant lesions in exfoliative cytology Methodology: This was a quantitative retrospective cross sectional study conducted at Birat Medical College Teaching Hospital from 24th December 2014 to 24th December 2018. All the exfoliative samples received at the lab were accepted in our study. Results: Of the 300 samples received, the maximum number were those of sputum followed by pleural fluid and ascitic fluid. Peritoneal fluid, Cerebrospinal fluid, synovial fluid, fluid from suspected abscess and breast fluid were also received. Malignancy was found in 1.67% of the samples studies. Conclusion: A study of different cytomorphological features of exfoliative cytology samples will help in establishing the role of cytology as an important diagnostic tool in improving the effectiveness of diagnosis , treatment & prognosis of the patient in the medical field.  

scholarly journals Histopathology of Sinonasal and Nasopharyngeal Neoplastic Lesions in a Tertiary Care Center of Western Nepal: A Descriptive Cross-sectional Study

2021 ◽  
Vol 59 (239) ◽  
Author(s):  
Sudeep Regmi ◽  
Arnab Ghosh ◽  
Dilasma Gharti Magar ◽  
Sushma Thapa ◽  
Krishna Prasad Koirala ◽  
...  
Keyword(s):  
Care Center ◽  
Benign Lesion ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Tertiary Care Center ◽  
Sectional Study ◽  
Cross Sectional ◽  
Neoplastic Lesions ◽  
Malignant Lesions ◽  
Nasopharyngeal Masses

Introduction: Sinonasal and nasopharyngeal regions harbor diverse clinical conditions including many non-neoplastic and neoplastic lesions presenting with nasal obstruction, facial pain and swelling, rhinorrhea, epistaxis, and other oral, ear, and orbital symptoms. Histopathology of excised lesions is the mainstay for the definitive diagnosis and management of neoplastic lesions. The aim of this study is to find out the prevalence of neoplastic lesions among sinonasal and nasopharyngeal masses. Methods: This was a descriptive cross-sectional study conducted among sinonasal and nasopharyngeal masses in the Department of Pathology of a tertiary care center of western Nepal with primary data of 20 years from January 2001 to May 2020. Ethical approval was taken from the Institutional Review Committee. Convenience sampling method was used. Data management and statistical analysis were done using Statistical Package for Social Sciences. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage. Results: Out of 395 sinonasal and nasopharyngeal lesions, 134 (33.92%) (29.26-38.58 at 95% Confidence Interval) were neoplastic lesions. The malignant lesions were found to be 60 (44.77%). Inverted papilloma was the most common benign lesion comprising 28 (20.89%) of cases, and squamous cell carcinoma and nasopharyngeal carcinoma were the most common malignant lesions comprising 12 (8.95%) cases each. Conclusions: This study observed a variety of neoplastic lesions. The most common benign lesion was nasal polyp and squamous cell carcinoma and nasopharyngeal carcinoma were the most common malignant lesions.

Side Effects of Chemotherapy and Cancer Treatment in Tertiary Care Teaching Hospital

2016 ◽  
Vol 2 (1) ◽  
pp. 62-78
Author(s):  
. Hemraj ◽  
Raj Kumar ◽  
Sourabh Kosey ◽  
Amit Sharma ◽  
Nalini Negi
Keyword(s):  
Side Effects ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Informational Needs ◽  
Cross Sectional ◽  
Clinical Pharmacists ◽  
Medical College ◽  
Related Information ◽  
The Common ◽  
Chemotherapy Patients

To determine the most common physical side effects experienced by local chemotherapy patients. Their perceptions of these side effects and informational needs from clinical pharmacists were also evaluated. This was a single center, observational cross-sectional study conducted at department of General Surgery, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab. A face to face interview was conducted. Information collected included chemotherapy related side effects after last chemotherapy experience, the most worrisome side effects, overlooked by healthcare professionals and the preferred method, amount and source of receiving related information. In this study, hundred patients were enrolled out of them 48 were male and 52 were female. When differential calculations was done, common side effects or adverse effects of chemotherapy in the patients of breast, lung cancer, Ovarian Cancer, Colon cancer, Prostate cancer, Lymphoma Cancer, Cervix cancer where there is much irregular medicine intake 57.4% may be due to common problem of joint pain reported by all the patients under study, with the consecutive problem of nausea and vomiting. The high prevalence of chemotherapy related side effects among local patients is a major concern and findings of their perceptions and informational needs may serve as a valuable guide for clinical pharmacists and physicians to help in side effect management. This study shows the common problems reported by the patients when they are suffering from cancer condition, according to their incidence perceptions as experienced by the patient, this will allow the physician and clinical pharmacist to effectively counsel and manage the common symptoms as reported prior to its occurrence in the patient, so that withdrawal can be checked.

Rapid detection of Rotavirus antigen in stool sample of acute diarrheic children

2012 ◽  
Vol 6 (1) ◽  
pp. 11-13
Author(s):  
Sushmita Roy ◽  
S.M. Shamsuzzaman ◽  
K.Z. Mamun
Keyword(s):  
Stool Sample ◽  
Rapid Detection ◽  
Cross Sectional Study ◽  
Rapid Diagnosis ◽  
Age Group ◽  
College Hospital ◽  
Cross Sectional ◽  
Rotavirus Infection ◽  
Medical College ◽  
Stool Samples

Rotavirus is one of the leading causes of pediatric diarrhea globally. Accurate and rapid diagnosis of Rotavirus diarrhea should reduce unnecessary use of antibiotics and ultimately reduce drug resistance. Study was designed for rapid diagnosis of Rotavirus antigen in stool sample by ICT (Immunochromatographic test) as well as to observe the seasonal variation of rotavirus infection. This cross sectional study was carried out in the department of Microbiology, Dhaka Medical College from January 2011 to December 2011. Eighty stool samples were collected from Dhaka Shishu Hospital and Dhaka Medical College Hospital. All samples were tested for rotavirus antigen by ICT. Among 80 patients, 42 (52.5%) samples were positive for rotavirus antigen. Among these 42 positive samples, 30 (71.43%) were from 0-12 months of age group, 10 (23.81%) from 13 to 24 months of age group and rest 2 (4.76%) from 25 to 36 months of age group. Rotavirus Ag was detected in stool samples from January to April and another peak episode from October to December. Considering the importance of Rotavirus associated diarrhea, rapid detection of Rotavirus infection in human is substantially needed and should be routinely practiced.DOI: http://dx.doi.org/10.3329/bjmm.v6i1.19354 Bangladesh J Med Microbiol 2012; 06(01): 11-13

Suicidal Death Autopsy Analysis at Dhaka Medical College

1970 ◽  
Vol 40 (1) ◽  
pp. 18-21 ◽  
Author(s):  
MN Hossain ◽  
Z Rahman ◽  
S Akhter
Keyword(s):  
Forensic Medicine ◽  
Causes Of Death ◽  
Cross Sectional Study ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Autopsy Report ◽  
Common Causes ◽  
Suicidal Death

A cross sectional study was carried out at the department of Forensic Medicine in Dhaka Medical College during the period of January 2008 to December 2009. Data were collected from 3rd copy of the post mortem reports which were preserved in the department of Forensic Medicine with the verbal consent of the doctors who performed autopsy report. During this period total 5114 autopsies were conducted. Out of this 970 cases (19%) were suicidal in nature. It was noticed that all suicidal deaths occurred from 10 years to all age group respectively, but top amongst age group of suicidal deaths occurred in between 21 to 30 years of people. Suicidal deaths are more common in female than male. Suicidal deaths due to hanging is highest, next common causes of death due to organophosphorus compund poisoning. Suicidal deaths by hanging is more in female than male but in poisoning cases male are more lvictimised than female. Objectives of our study are to see the occurrence and methods of suicidal death. DOI: http://dx.doi.org/10.3329/bmj.v40i1.9957 BMJ 2011; 40(1): 18-21

Comparison of Heffner Criteria and Light Criteria in Differentiating Exudative and Transudative Pleural Effusion

2020 ◽  
Vol 22 (3) ◽  
pp. 141-145
Author(s):  
Krishna Chandra Devkota ◽  
S Hamal ◽  
PP Panta
Keyword(s):  
Pleural Effusion ◽  
Cross Sectional Study ◽  
Pleural Space ◽  
Sectional Study ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
Medical College ◽  
The Common ◽  
The Mean ◽  
Exudative Pleural Effusion

Pleural effusion is present when there is >15ml of fluid is accumulated in the pleural space. It can be divided into two types; exudative and transudative pleural effusion. Tuberculosis and parapneumonic effusion are the common cause of exudative pleural effusion whereas heart failure accounts for most of the cases of transudative pleural effusion. This study was a hospital based cross sectional study performed at Nepal Medical College during the period of January 2016-December 2016. A total of 50 patients who fulfilled the inclusion criteria were enrolled. Pleural effusion was confirmed by clinical examination and radiology. After confirmation of pleural effusion, pleural fluid was aspirated and was analysed for protein, LDH, cholesterol. The Heffner criteria was compared with Light criteria to classify exudative or transudative pleural effusion. Among 50 patients, 30 were male and 20 were female. The mean age of patient was 45.4±21.85 years. The sensitivity and specificity of using Light criteria to detect the two type of pleural effusion was 100% and 90.9%, whereas using Heffner criteria was 94.87%, 100% respectively(P<0.01). There are variety of causes for development of pleural effusion and no one criteria is definite to differentiate between exudative or transudative effusion. In this study Light criteria was more sensitive whereas Heffner criteria was more specific to classify exudative pleural effusion. Hence a combination of criteria might be useful in case where there is difficulty to identify the cause of pleural effusion.

Perceptions of Final Year Medical Students about Family Medicine as A Career Choice in Pakistan

2020 ◽  
Author(s):  
Dur-e- Nishat
Keyword(s):  
Medical Students ◽  
Family Medicine ◽  
Medical Profession ◽  
Healthcare Services ◽  
Developed Countries ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Medical College ◽  
Chi Square Test

Background: Family medicine is a field in which complete and detailed set of healthcare services are provided to the patients and their families. In developed countries, freshly graduated students choose family medicine as a priority for their career. However, in Pakistan it is not the case. The present study is undertaken to determine the perceptions of final year medical students’ about Family Medicine as a viable career. Methods: A total number of 504 students participated in the study. This was a cross-sectional study. The study participants were in their final year of medical college. Data was collected using a preapproved questionnaire. Data was entered and analyzed via SPSS version 17 and Chi-Square test was used post-stratification. Results: Only 14.3% (n=72) medical students had heard about Family Medicine. Only 18% (n=92) would select family medicine as a profession. The most frequent rationale for choosing the field of Family Medicine was the variety of patients seen in general practice (55.4% n=51). Conclusion: There is a dire need to focus on increasing awareness about the field of family medicine among medical students. The students should be counseled on the advantages along with the disadvantages of choosing this field as a medical profession.

To Study the Clinical Profile and Management of Cellulitis of Lower Limb in Northern India

2021 ◽  
pp. 153473462098667
Author(s):  
Tripta S. Bhagat ◽  
Luv Kumar ◽  
Prakhar Garg ◽  
Apoorv Goel ◽  
Amit Aggarwal ◽  
...  
Keyword(s):  
Bacterial Infection ◽  
Lower Limb ◽  
Surgical Intervention ◽  
Significant Risk ◽  
Cross Sectional Study ◽  
Common Complication ◽  
Cross Sectional ◽  
Medical College ◽  
Northern India ◽  
Working Age

Cellulitis is a bacterial infection of the dermis and subcutaneous tissues occupying a large proportion of hospital beds. This study was conducted for analysis of patients with cellulitis according to their demographics and clinical presentation and to examine their comorbidities, complications, and its management. This observational cross-sectional study was conducted in the Department of Surgery at Santosh Medical College and Hospitals involving a total of 60 cases having cellulitis and other soft tissue infections of lower limb. Analysis of their demographic profile, management, and complications was done. Cellulitis is seen commonly in males, 46 (76.6%). The mean age of patients affected by cellulitis in the study was 36.4 ± 1.23 years. The most common site affected is leg involving more people in field jobs. The most common risk factor was trauma in 46.6%, and other factors were diabetes mellitus and smoking, while abscess formation was the most common complication observed in 36.6% of cases. A total of 56.6% cases were managed conservatively, while 43.3% cases required surgical intervention. Mean hospital stay in this study was 5.02 ± 0.23 days. It was concluded that cellulitis is subcutaneous, spreading bacterial infection is more common in males, and its incidence is highest in working age group population. Lower limb is commonly involved. Trauma, smoking, and diabetes are significant risk factors for development of cellulitis. Abscess is the most common complication. About 50% patients with cellulitis can be managed conservatively and the rest require surgical intervention.

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