Melaleuca spp. essential oil and its medical applicability.  A Brief Review

Medicinal plants have long been used as an alternative in the treatment of diseases, whether using extracts, essential oils and / or bioactive components. Thus, the use of medicinal plants, with popularly known effects for the treatment of infections, has gained prominence, in research related to extracts and essential oils of medicinal plants, in an attempt to discover and future application of new molecules with antimicrobial and / or effect coadjuvant molecules to antimicrobials on the market. Studies with species of Melaleuca spp., Demonstrate wide application of its essential oil, without treating skin infections, microbial infections, herpes, diseases associated with pathogenic microorganisms of the oral cavity. The emerging microbial resistance to the drugs currently available on the market, has been affected by both researchers and the general population, so that the research experimented with was conducted revealing a high synergistic potential between drugs and natural drugs, present in drugs. In view of the above, this study aimed to present, through a bibliographic survey, a use of medicinal plants in the face of microbial resistance, as well as medicinal therapy based on the use of essential oils from alternative tea tree, leucadendron tea tree and quinquenervia tea tree, already inclusion in the literature.

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The Volatile Phytochemistry of Seven Native American Aromatic Medicinal Plants

Plants ◽

10.3390/plants10061061 ◽

2021 ◽

Vol 10 (6) ◽

pp. 1061

Author(s):

Sims K. Lawson ◽

Prabodh Satyal ◽

William N. Setzer

Keyword(s):

Native American ◽

Medicinal Plants ◽

Essential Oil ◽

Essential Oils ◽

Palmitic Acid ◽

Methyl Salicylate ◽

Chromatographic Techniques ◽

Germacrene D ◽

First Time ◽

Gaultheria Procumbens

As part of our evaluation of essential oils derived from Native American medicinal plants, we have obtained the essential oils of Agastache foeniculum (Pursch) Kuntze (Lamiaceae), Gaultheria procumbens L. (Ericaceae), Heliopsis helianthoides (L.) Sweet (Asteraceae), Liatris spicata (L.) Willd. (Asteraceae), Pycnanthemum incanum (L.) Michx. (Lamiaceae), Smallanthus uvedalia (L.) Mack. ex Mack. (Asteraceae), and Verbena hastata L. (Verbenaceae) by hydrodistillation. The essential oils were analyzed by gas chromatographic techniques. The essential oil of A. foeniculum was dominated by estragole (88–93%), while methyl salicylate (91%) dominated the G. procumbens essential oil. Germacrene D was the major component in H. helianthoides (42%) and L. spicata (24%). 1,8-Cineole (31%) and α-terpineol (17%) were the main compounds in P. incanum essential oil. The essential oil of S. uvedalia showed α-pinene (24%), perillene (15%), and β-caryophyllene (17%) as major components. Verbena hastata essential oil was rich in 1-octen-3-ol (up to 29%) and palmitic acid (up to 22%). Four of these essential oils, H. helianthoides, L. spicata, P. incanum, and V. hastata, are reported for the first time. Additionally, the enantiomeric distributions of several terpenoid components have been determined.

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Chemical composition, antimicrobial activity and biological properties of essential oils

International Journal of Life Sciences ◽

10.3126/ijls.v9i2.12043 ◽

2015 ◽

Vol 9 (2) ◽

pp. 9-13 ◽

Cited By ~ 2

Author(s):

Amir Hossein Saeidnejad ◽

Peyman Rajaei

Keyword(s):

Chemical Composition ◽

Medicinal Plants ◽

Essential Oil ◽

Essential Oils ◽

Antimicrobial Properties ◽

Biological Properties ◽

Antioxidant Agents ◽

Ancient Times ◽

High Concentrations ◽

Oil Repellent

Essential oils constitute a heterogeneous collection of chemical compounds. Their main characteristics are that they all synthesized by plants and are volatile and mostly soluble in ethanol. They have traditionally been obtained from plants and they have been widely used for insecticidal, medicinal and cosmetic purposes. Essential oils contains about 20–60 components at quite different concentrations and they are characterized by two or three major components at fairly high concentrations. Lately, the essential oils and various extracts of plants have gained special interest as sources of natural antimicrobial and antioxidant agents because of the resistance to antibiotics that some microorganisms have acquired and the possible toxicities of the synthetic antioxidants. Spices consumed daily in different types of food to improve flavors, since ancient times, are well known for their antioxidant and antimicrobial properties. During recent decades, numerous numbers of plants have been monitored for their possible role as repellents and insecticides. In this review, the chemical composition profile of some important medicinal plants was evaluated, then antimicrobial properties of a number of essential oils was compared. Antioxidant activity of some essential oils was also considered. Finally, essential oil repellent properties an an important characteristics was evaluated. Further investigation for available data related to the other biological properties of medicinal plants essential oil is recommended.DOI: http://dx.doi.org/10.3126/ijls.v9i2.12043 International Journal of Life Sciences 9 (2) : 2015; 9-13

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Development of bioactive/active additives based on essential oils: A review

Medicinal Plant Communications ◽

10.37360/mpc.20.3.4.12 ◽

2020 ◽

Vol 3 (4) ◽

pp. 60-67

Author(s):

Jessica Alarcón-Moyano ◽

◽

Silvia Matiacevich ◽

Keyword(s):

Medicinal Plants ◽

Essential Oil ◽

Essential Oils ◽

Freeze Drying ◽

The Other ◽

Wall Material ◽

Oil Oxidation ◽

Active Additive ◽

Wall Materials ◽

Selection For

The use of bioactive/active additives has been increasing in recent years, especially those derived from medicinal plants such as essential oils. However, due to essential oil oxidation it is necessary to protect it by encapsulation techniques such as: emulsion, spray- and/or freeze-drying as the most economical techniques. On the other hand, an important factor is to determine the appropriate wall material to obtain a prolonged or controlled release in the food or in the organism. Therefore, several factors affect the release of the compounds such as the type, amount of wall material and/or combination of wall materials. Therefore, the knowledge of all the aforementioned factors is important in order to make an adequate selection for the development of a bioactive/active additive based on essential oils.

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Selection of the optimal composition of vegetable oil and chlorophyllipt oil components

Ukrainian Journal of Veterinary and Agricultural Sciences ◽

10.32718/ujvas2-3.03 ◽

2019 ◽

Vol 2 (3) ◽

pp. 11-14

Author(s):

R. M. Sachuk ◽

Ya. S. Stravsky ◽

YU. V. Horyuk ◽

O. A. Katsaraba ◽

S. V. Zhyhalyuk

Keyword(s):

Essential Oil ◽

Essential Oils ◽

High Efficiency ◽

Skin Diseases ◽

Antimicrobial Properties ◽

Optimal Composition ◽

Tea Tree ◽

E Coli ◽

Siberian Pine ◽

Oily Solution

Investigate the antimicrobial properties of various concentrations of vegetable essential oils in combination with an oil solution of chlorophyllipt as possible ingredients for ointments for wounds. Microbiological tests were performed according to standard methods using E. coli test cultures, S. aureus, Str. agalactiae and P. fluorescens. The results of studies of antibacterial activity of both individual ingredients and their combinations are presented, namely: 4 % essential oil of Siberian pine, 2 % essential oil of eucalyptus, 1.5 % essential oil of cloves, 1.5 % of essential oil of cedar, 2.0 % tea tree essential oil and 1.0 % chlorophyllipt oil solution. Bacteria, which are usually typical agents of wound infections, have been found to be quite sensitive to the drugs tested. High activity of essential oils and oily solution of chlorophyllipt with respect to E. coli and S. aureus was revealed. In particular, a 1.0 % oily solution of chlorophyllipt caused staphylococcal growth retardation zones whose diameters were 1.4 times larger than the antibiotic clindamycin. It was determined that representatives of gram-negative microflora were more sensitive to the investigated essential oils and chlorophyll. The optimal composition of the experimental drug called “Ointment for wounds” is offered. The results of preclinical testing showed a sufficiently high efficiency compared to traditional means. The results obtained with regard to antimicrobial activity indicate the prospect of using preparations based on the essential oil of Siberian pine, eucalyptus, carnation, cedar, tea tree and oil solution of chlorophyllipt for the treatment of skin diseases in animals. This data will help to develop new effective and safe veterinary treatments for wound care.

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In Vitro Antimicrobial Activity of Frankincense Oils from Boswellia sacra Grown in Different Locations of the Dhofar Region (Oman)

Antibiotics ◽

10.3390/antibiotics9040195 ◽

2020 ◽

Vol 9 (4) ◽

pp. 195 ◽

Cited By ~ 1

Author(s):

Vita Di Stefano ◽

Domenico Schillaci ◽

Maria Grazia Cusimano ◽

Mohammed Rishan ◽

Luay Rashan

Keyword(s):

Essential Oil ◽

Essential Oils ◽

Volatile Components ◽

Clinical Settings ◽

Antifungal Effect ◽

Microbial Infections ◽

Grade 3 ◽

The Comparative Study ◽

Boswellia Sacra

Frankincense essential oils from Boswellia sacra have been commonly used to treat microbial infections from as early as the 11th century. The main feature of the plant is its gum resin, from which it is possible to obtain essential oils. In the present study, we focused on the comparative study of the oils extracted from the resins of three different Boswellia sacra cultivars (Najdi, Sahli and Houjri). From each of frankincense resin three successive essential oil samples (Grade 1, Grade 2, Grade 3) were obtained. Houjri gum resin gave the lowest percentage (5%) of total essential oil content but showed the maximum number of volatile components in all three grades. Najdi Grade 2 essential oil showed a minimum inhibitory concentration (MIC) of 52 mg/mL toward relevant pathogens Staphylococcus aureus and Pseudomonas aeruginosa, and samples from Grade 2 of Sahily and Houjiri were particularly active against a dermatological strain Propionibacterium acnes, displaying MIC values of 0.264 and 0.66 mg/mL, respectively. Data obtained from in vitro studies showed that all essential oils had a significant antifungal effect against Candida albicans and Malassezia furfur, showing MIC values ranging from 54.56 to 0.246 mg/mL. This work aims to increase the number of substances available in the fight against pathogens and to combat the phenomenon of antibiotic resistance, encouraging the use of alternative resources, especially in non-clinical settings (farms, food processing, etc.).

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Researches on the capitalization of some medicinal plants to obtain essential oils by using the performant innovative installation EUV 2x1000 type

E3S Web of Conferences ◽

10.1051/e3sconf/201911203012 ◽

2019 ◽

Vol 112 ◽

pp. 03012

Author(s):

Ion Grigore ◽

Andreea Iulia Grigore ◽

Laurentiu-Constantin Vlăduţoiu ◽

Mario Cristea ◽

Elena Sorica ◽

...

Keyword(s):

Medicinal Plants ◽

Essential Oil ◽

Essential Oils ◽

Water Vapour ◽

Experimental Research ◽

Volatile Components ◽

Research Results ◽

Family Associations

The article includes research on the production of essential oils from medicinal plants by applying water vapour distillation, the method most commonly used for the extraction of essential oils from plants. The results consist of extracting the essential oil from 2 types of medicinal plants: lavender and mint with the help of the EUV installation. The paper highlights the important aspects of obtaining quality products, on economically advantageous terms, addressing both specialists, farmers in larger farms and family associations. The article presents the experimental research results on obtaining essential oils from medicinal plants. Oils obtained by this method contain only volatile components, while wax and volatile resins are not found in the finished product.

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Review: Inhibition of bacterial quorum sensing by plant extracts

Israel Journal of Plant Sciences ◽

10.1080/07929978.2015.1067076 ◽

2015 ◽

Vol 62 (4) ◽

pp. 294-297 ◽

Cited By ~ 2

Author(s):

Ludmila Yarmolinsky ◽

Moshe Bronstein ◽

Jonathan Gorelick

Keyword(s):

Quorum Sensing ◽

Medicinal Plants ◽

Cell Communication ◽

Antibiotic Development ◽

Promising Target ◽

Microbial Infections ◽

Bacterial Quorum Sensing ◽

The Face ◽

Bacterial Quorum ◽

New Treatments

Bacterial quorum sensing (QS) is a form of cell-to-cell communication which is vital to the pathogenicity of many bacteria, and therefore a promising target for the development of new treatments for microbial infections. While many medicinal plants possess antibacterial activity, only a few plants have been shown to target quorum sensing. In the face of increased microbial resistance to existing antibiotics coupled with the decline in novel antibiotic development, QS inhibitors from medicinal plants is a promising direction for new antibacterial treatments,. The purpose of this review is to summarize the verified data on the anti-QS properties of medicinal plants and the various mechanisms of their actions.

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Volatile Oil Composition of Some Commercial Medicinal Plants Sold in Konya, Turkey

Asian Plant Research Journal ◽

10.9734/aprj/2019/v2i126588 ◽

2019 ◽

pp. 1-5

Author(s):

Eray Tulukcu

Keyword(s):

Medicinal Plants ◽

Essential Oil ◽

Essential Oils ◽

Oil Content ◽

Local Community ◽

Volatile Oil ◽

Essential Oil Composition ◽

Oil Composition ◽

Thyme Essential Oil ◽

The Difference

This study was conducted to determine the essential oil composition of some medicinal plants from herbalists that local community have interest in; The research was carried out in the Medicinal Plants Laboratory of Konya, in 2014 – 2015. The medicinal plants used in the research were supplied by herbalists and wholesalers who supply medicinal plants in Konya. At the end of this study, essential oil composition of medicinal plants ranged from 0.71 % (Daphne) to 5% (Thyme). The lavender essential oil composition ranged between 2% and 5%, while the composition of thyme essential oil ranged between 1% and 5%. There are several reasons for the change observed in the essential oil content of medicinal plants. In general, the effect of difference in the proportion of essential oils of the medicinal plants used in the study was as a result of the difference in regions, domestically and abroad where these plants were collected.

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The application of tea tree essential oil in dentistry

Stomatoloski glasnik Srbije ◽

10.2298/sgs0702106m ◽

2007 ◽

Vol 54 (2) ◽

pp. 106-114

Author(s):

D. Markovic ◽

B. Mirkovic ◽

T. Jovanovic ◽

A. Knezevic ◽

T. Nastovski

Keyword(s):

Essential Oil ◽

Essential Oils ◽

Fusobacterium Nucleatum ◽

Viral Diseases ◽

Prevotella Intermedia ◽

Tea Tree Oil ◽

Melaleuca Alternifolia ◽

Tea Tree ◽

Plant Substances

Essential oils are widely used in medicine, dentistry and cosmetology as flavour and odour corrigents in various substances for oral hygiene. The aim of this study was to present comprehensively the possibilities for application of Melaleuca Alternifolia essential oil in dentistry based on the analysis of contemporary scientific and professional publications. The application of Tea tree essential oil in the treatment of periodontal, fungal and viral diseases is very efficient. The study of antimicrobial potential of ten different essential oils confirmed the efficiency of Tea tree oil against numerous Gram+ and Gram- bacteria. In vitro studies of bacteriostatic, bactericidal and fungicidal effect of Tea tree oil solution against ten different microorganisms confirmed sensitivity of the following microorganisms: Actinobacillus actinomycetemcomitans, Fusobacterium nucleatum and Porphyromonas gingivalis, and slightly weaker effect against Streptococcus Mutans and Prevotella intermedia. Tea tree is very effective in the treatment of various diseases and is an introduction and momentum for the application of plant substances in the treatment of numerous diseases in dentistry. .

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Characterization and Chemical Composition Analysis of Tea Tree (Meleuca alternifolia) Leaf Hydrosols Growing on Lombok Island

Jurnal Penelitian Pendidikan IPA ◽

10.29303/jppipa.v8i1.1239 ◽

2022 ◽

Vol 8 (1) ◽

pp. 119-123

Author(s):

Baiq Riyankati ◽

Surya Hadi ◽

Sri Seno Handayani

Keyword(s):

Chemical Composition ◽

Essential Oil ◽

Essential Oils ◽

Composition Analysis ◽

Distilled Water ◽

Tree Leaves ◽

Tea Tree ◽

Chemical Composition Analysis ◽

By Products ◽

Lombok Island

Tea tree is an essential oil-producing plant from Australia which is also found growing in several parts of Indonesia, including the island of Lombok. So far, tea tree essential oil producers on the island of Lombok do not utilize by-products in the form of hydrosol (distilled water) produced in the process of making essential oils. In this study, the characterization and analysis of the chemical composition of the hydrosol of tea tree leaves growing on the island of Lombok was carried out. The characteristic aroma of hydrosol is similar to that of tea tree essential oil. The results of the GC-MS analysis also showed that the hydrosol of tea tree leaves also had similarities with the essential oil, composed of major compounds in the form of trans-caryophyllene (28.58%), limonene (13.98%) and terpinen-4-ol (16.27%). Other compounds detected were -pinene (4.14%), -pinene (6.50%), -myrcene (8.09%), -terpineol (10.10%) and -terpinene (5.77%).

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