scholarly journals Peculiarities of age-related morphological changes in the dermal-hair cover of the Pamir yak ecotype bred in the mountain zone of Northern Tajikistan

Author(s):  
A. R. Mukhiddinov ◽  
N. Sh. Kamolov

In the process of animal adaptation to changing environmental conditions, the hair cover, which is known to perform a heat-protective function primarily, plays a significant role. The hair cover of animals undergoes changes depending on the season of the year and the natural and climatic zone in which the animals live. It has its peculiarities in different species (breeds). The nature and features of the hair cover of animals are often used by scientists to compile zoological systematics, assess the health and constitution types of animals, their acclimatisation ability, etc. In this article, the authors reviewed age-related changes in weight, size, thickness and tightness of animal skins (changes in skin thickness from the ridge to the floor) and features of the hair cover of the skin’s yaks of Northern Tajikistan. The authors also noted that in all animals, the weight of hides increases in proportion to the rise in live body weight. The absolute importance of skins, up to the age of half a year of yaks, is almost two times higher than cattle. In yaks at one- and three years old, the thick- ness of skins at the standard point in these animals is somewhat comparable. But the thickness of the pelts in the collar and area of hiding yak next to the floor remains higher by about 25-40%. Yaks are known to have three main categories of hair: long hairs (in the abdominal region of the hide and on the tail), short hairs (on the rump, neck and back) and down inches (in all parts of the animal’s fur). Long coats are also the thickest. The hair length of newborn yaks is 187.60±2.66 mm, of one-year-old yaks 452.50±2.52 mm, and of six-year-old yaks, it reaches 475 mm. The authors determined the total amount of hair of different categories in the three topographic parts of the body: in the rump, the sum of hair is 1545 hair units; in the collar part, the sum of hair is 1590 hair units; in the abdominal area of the body the sum of hair is 1770 hair units. The collar and rump do not have long hairs, unlike the abdomen. Downy hairs are characteristic of all parts of the hide but predominate in the scruff and collar. The dynamics of age-related changes in the hair cover of yaks have been determined.

1997 ◽  
Vol 85 (3_suppl) ◽  
pp. 1263-1271 ◽  
Author(s):  
Toshiaki Yanagida ◽  
Takaaki Asami

We investigated age-related changes in the distribution of body weight on soles of feet in 878 healthy subjects ranging from 5 to 80 years of age. By modifying Morton's Staticometer, we constructed an instrument for measuring body-weight distribution over three areas of soles of the feet, the big toe (inner forefoot), the other four toes combined (outer forefoot) and the heels for both feet, thus a total of six areas. The weights in the six areas were recorded at the completion of nine selected actions and postures. We observed that for inhaling and exhaling standing postures, generally younger subjects had a ratio close to 1:2:3 for weights recorded for the inner toe:outer toes:heels as observed by Morton, but elderly subjects had a smaller value than 3 for the heel. The body-weight distribution tended to shift from heels to outer toes across age groups, which was more distinctly observed in women than in men.


The aim of the study was to investigate the effects of Moringa oleifera aqueous seed extract on live body weight, gonadal and extragonadal dimensions and sperm reserves of Yankasa rams. Twenty five apparently healthy Yankasa rams aged 1-2 years and weighing 19.0 ± 2.1 Kg were used for the study. The rams were randomly selected into five groups: A, B, C, D and E with five rams in each group as treatment and control groups respectively. Groups A - D were given oral dose of Moringa oleifera aqueous seed extract at a dose rate of 1000, 2000, 3000, 4000 (mg/kg), respectively while group E was given 10 ml/kg water orally, daily for five months. Live body weight, gonadal and extragonadal reserves were determined according to standard techniques. The results showed a significant increase in live body weight in the months of April to June among rams treated with different doses of Moringa oleifera aqueous seed extract compared with the control group. The control group showed no significant differences in the body weight, gonadal and extragonadal dimensions and sperm reserves. In conclusion, the treatment of Yankasa rams with Moringa oleifera aqueous seed extract increased live body weight, but had no significant effects on gonadal and extragonadal dimensions and sperm reserves in Yankasa rams. Therefore, it is recommended that M. oleifera aqueous seed extract can be used at doses of 2000mg/kg to 3000mg/kg in Yankasa rams for optimum gain in live body weight.


Author(s):  
В. П. Бердник ◽  
О. О. Бублик ◽  
Т. М. Марченко ◽  
В. І. Щербак ◽  
О. Г. Трирог

Наведені результати випробування на 537 курчатах-бройлерах (635 контрольних) в умовах господарства препарату, виготовленого на основі розчину  полтавського бішофіту. У  курчат, яким давали препарат внутрішньо з водою,  порівняно з контролем, була більшою середня жива масса тіла у  43-добовому віці на 50 г, 73-добовому  – на 128 г і 111-добовому – на  103 г. До 43-добового віку загинуло із розрахунку від  початкової загальної кількості 16 (2,9 %) курчат-бройлерів  у дослідній групі і 30 (4,72 %) у контрольній. На контрольних  курчатах-бройлерах, порівняно із дослідними, мали економію на препараті, який не застосовували, і меншій кількості  використаних  кормів, але одержано значно більше збитків   через нижчі прирости живої маси тіла та більшу кількість загиблих. Економічна  вигода  від застосування препарату лише  до 43-добового віку курчат становить 5,8 гривень на  вкладену 1 гривню. Given results of test on 537 chickens-broilers (635 of control) in terms of economy drug produced on the basis of the solution of Poltava bishofit (SPB). Drug was given chickens-broilers of 5-day age group method internally with water in 3 cycles of 24-hour intervals over 7 times in each cycle and 7-day interval between cycles. The chicks, which were given the drug, compared with the control, had a greater average live weight of the body in 43-day age of 50 g, 73-day – 128 g and 111-day – 103 g it shows its positive effect on organisms of chicks up to 2,5 months (time of observations) after the last application in 38-th days of their lives. The drugs based on the SPB will have greater efficiency in the application of the repair chicks and adult hens, i.e. those who live more than 2,5 months. The 43-day age 16 broiler died of the calculation of the initial total number (2,9 %) in experimental group and 30 (4,72 %) in the control. On control broilers, compared with research, savings on the drug, which is not used, and smaller amounts of used feed, but we received much more losses due to lower increases in live body weight and more fatalities. The total value of the economic benefits of the drug only to 43-day age of chicks is 5,8 UAH on each invested 1 UAH.


1970 ◽  
Vol 8 (1) ◽  
pp. 10-12
Author(s):  
Meherunnessa Begum ◽  
Uttam Kumar Paul ◽  
Md Jahangir Alam

Context: Thymus is intimately related to the immuno regulatory mechanism of the body, its weight in general as well as at different age in a particular population might also be related to the overall immune status of that population. Thus the knowledge of the weight of the thymus at different ages may be helpful in planning of the medical and surgical treatment of thymus related problem as well as dealing patients from immunologic aspects Objective: To measure the age related changes in weight of the thymus gland of Bangladeshi people Study design: A descriptive type of study Place and period of study: The study was carried out in the Department of Anatomy, IPGMR Dhaka from October 1996 to March 1997. Materials: 40 (forty) thymuses from Bangladeshi cadaver of either sex were taken for this study. Method: The collected samples were divided into four age groups ranged from still born to sixty years old individuals and comparative studies were done between different age groups. Result: The thymuses increased significantly in weight steadily through the increasing age groups from the still born babies to <16yrs and then declines through the age still higher. Conclusion: In the present study the weight of the thymus increases through the increasing age groups and then declined. Key words: Thymus; Weight DOI: 10.3329/bja.v8i1.6101 Bangladesh Journal of Anatomy January 2010, Vol. 8 No. 1 pp. 10-12


2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Marguerite B. Vigliani

This paper presents two cases of women who had extensive vaginal adenosis from prenatal DES exposure, extending almost halfway down the vaginal canal. Both women were followed for decades with annual exams and Pap smears until after menopause. Clinical examination in both cases initially showed an absent pars vaginalis of the cervix, vaginal adenosis, and shallowness of the fornices. Several decades of annual exams showed these stigmata of DES exposure gradually disappear as the upper vagina progressively contracted. After menopause the upper vagina in both cases transformed into what appeared to be a normal cervix with all adenosis involuted into a normal endocervical canal. A timeline was created to show the morphological changes that were observed over time. This timeline illustrates how severe vaginal stenosis above the level of the squamocolumnar junction developed in middle age and was followed in the postmenopause by fusion of the upper vaginal walls in the midline resulting in the appearance of a normal, but prolapsed, cervix.


Author(s):  
M. Ibnelbachyr ◽  
I. Boujenane ◽  
A. Chikhi

SummaryThe Moroccan goat livestock is characterized by the existence of different phenotypes distributed among diverse geographic locations. The objective of this study was to analyse the morphometric traits that differentiate the Draa breed from the other local populations raised in areas close to its cradle zone. Eight morphometric measurements were taken on 287 goats in South-eastern and Southern Morocco. The variance analysis, fitting a model that included the random effect of animal and the fixed effects of population, gender and age of animal, was used. Mahalanobis distances were calculated between identified populations and an Unweighted Pairs Group Method Analysis tree was built. Draa goats had the highest height at withers (61.5 cm), heart girth (74.4 cm), body length (64.6 cm) and live body weight (27.2 kg). These morphometric traits varied significantly among populations as well as the age and the gender of animal. The most discriminating traits between the identified populations were the body length, the heart girth, the hair length, the horn length, the ear length and the live body weight. Draa animals had the largest genetic distances from the other populations and appeared more distinguished from them. This differentiation can contribute in defining the phenotypic standard of the breed and in orienting its genetic improvement programs in the future.


2020 ◽  
pp. 57-61
Author(s):  
V. M. Chertok ◽  
V. A. Nevzorova ◽  
A. K. Savchenko ◽  
O. V. Miroshnichenko ◽  
A. V. Laryushkina

Objective: Analysis of age-related changes of microcirculatory bed of bulbar conjunctiva.Methods: 46 individuals of both sexes, divided into 5 age groups according to WHO recommendations, were examined. Biomicroscopy of bulbar conjunctiva was performed using a non-mydriatic retinal camera TOPCON TRC-NW8F (Japan); the obtained images were processed with a mea‑ suring device of automated analysis system ImageScope (Leica, Germany).Results: The average diameter of arterioles, arterioleto-venule ratio (AVR) and specific density of capillaries were the largest, and the diameter of venules was the smallest among the subjects aged 18–44 years. The most sensitive indicators of the state of microcirculatory bed were AVR and the specific density of capillaries, the values of which in the group of 45–59-year-olds were 10–11% lower than in people aged 18–24 and 25–44 years. Differences in other indicators between people aged 18-24 and 45–59 years were not significant. Between the groups of 60–74 and 75–86-year-old participants of the study, pronounced differences (about 18%) were found only in the specific density of capillaries: compared with 18–24 and 45–59-year-olds, this indicator decreased by almost 1.5 times, AVR – only by a third, and changes in the average diameter of arterioles and venules did not exceed 9–12%. Elderly people more often demonstrated arteriolar spasm, their uneven caliber, avascular fields and other disorders of the structure of the micro‑ circulatory bed.Conclusions: As the body ages, in the microcirculatory bed of the bulbar conjunctiva, the number of atypical vascular formations increases, the diameter of the arterioles decreases, the AVR and the specific density of capillaries decrease, the diameter of the venules increases. 


2021 ◽  
Vol 10 (3) ◽  
pp. 108-111
Author(s):  
I. G. Pashkova

The aim of the study was to investigate age-related changes in bone mineralization indicators in the lumbar vertebrae in women with normal body weight living in the conditions of the Northern region.Material and methods. A complex somatometric examination and quantitative assessment of the bone tissue mineral density in the lumbar vertebrae were performed according to dual-energy X-ray absorptiometry of a group of Slavic women (n=127) with a normal body weight (BMI values from 18.5 to 24.9 kg/m2) aged 20 to 87 years, permanently residing in the Republic of Karelia. Statistical processing of the material was performed using the program "STATISTICA 6.0".Results. The BMI values in women increased significantly every decade of life. Direct correlations of mineral bone density (MBD) with the body length (r=0.46, p<0.001), with the body surface area (r=0.46, p<0.001), with absolute muscle mass (MM) (r=0.39, p<0.001), and with body mass (r=0.29, p<0.001) were revealed. No significant correlation with the adipose mass was found. The incidence of low MBD of the lumbar vertebrae was 48%: osteopenia was in 29%, osteoporosis was in 19% of women. The analysis of the component composition of the body in women with different levels of bone mass showed significant differences in the absolute content of muscle mass.Conclusion. In women with a normal BMI, body weight and muscle mass play an essential role in maintaining lumbar vertebrae bone mineral density.


BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Lingbi Jiang ◽  
Mingming Yang ◽  
Shihui He ◽  
Zhengyang Li ◽  
Haobin Li ◽  
...  

Abstract Background Colorectal cancer is a malignant gastrointestinal cancer, in which some advanced patients would develop cancer cachexia (CAC). CAC is defined as a multi-factorial syndrome characterized by weight loss and muscle loss (with or without fat mass), leading to progressive dysfunction, thereby increasing morbidity and mortality. ApcMin/+ mice develop spontaneous intestinal adenoma, which provides an established model of colorectal cancer for CAC study. Upon studying the ApcMin/+ mouse model, we observed a marked decrease in weight gain beginning around week 15. Such a reduction in weight gain was rescued when ApcMin/+ mice were crossed with MMP12−/− mice, indicating that MMP12 has a role in age-related ApcMin/+-associated weight loss. As a control, the weight of MMP12−/− mice on a weekly basis, their weight were not significantly different from those of WT mice. Methods ApcMin/+; MMP12−/− mice were obtained by crossing ApcMin/+ mice with MMP12 knockout (MMP12 −/−) mice. Histological scores were assessed using hematoxylin-eosin (H&E) staining. MMP12 expression was confirmed by immunohistochemistry and immunofluorescence staining. ELISA, protein microarrays and quantitative Polymerase Chain Reaction (qPCR) were used to investigate whether tumor could up-regulate IL-6. Cell-based assays and western blot were used to verify the regulatory relationship between IL-6 and MMP12. Fluorescence intensity was measured to determine whether MMP12 is associated with insulin and insulin-like growth factor 1 (IGF-1) in vitro. MMP12 inhibitors were used to explore whether MMP12 could affect the body weight of ApcMin/+ mice. Results MMP12 knockout led to weight gain and expansion of muscle fiber cross-sectional area (all mice had C57BL/6 background) in ApcMin/+ mice, while inhibiting MMP12 could suppress weight loss in ApcMin/+ mice. MMP12 was up-regulated in muscle tissues and peritoneal macrophages of ApcMin/+ mice. IL-6 in tumor cells and colorectal cancer patients is up-regulation. IL-6 stimulated MMP12 secretion of macrophage. Conclusions MMP12 is essential for controlling body weight of Apc Min/+ mice. Our study shows that it exists the crosstalk between cancer cells and macrophages in muscle tissues that tumor cells secrete IL-6 inducing macrophages to up-regulate MMP12. This study may provide a new perspective of MMP12 in the treatment for weight loss induced by CAC.


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