scholarly journals Human cortical prostheses: lost in translation?

2009 ◽  
Vol 27 (1) ◽  
pp. E5 ◽  
Author(s):  
Stephen I. Ryu ◽  
Krishna V. Shenoy

Direct brain control of a prosthetic system is the subject of much popular and scientific news. Neural technology and science have advanced to the point that proof-of-concept systems exist for cortically-controlled prostheses in rats, monkeys, and even humans. However, realizing the dream of making such technology available to everyone is still far off. Fortunately today there is great public and scientific interest in making this happen, but it will only occur when the functional benefits of such systems outweigh the risks. In this article, the authors briefly summarize the state of the art and then highlight many issues that will directly limit clinical translation, including system durability, system performance, and patient risk. Despite the challenges, scientists and clinicians are in the desirable position of having both public and fiscal support to begin addressing these issues directly. The ultimate challenge now is to determine definitively whether these prosthetic systems will become clinical reality or forever unrealized.

2019 ◽  
Vol 8 (1) ◽  
pp. 221-235 ◽  
Author(s):  
Daniella De Paula Chiesa ◽  
Mário Antônio Sanches ◽  
Daiane Priscila Simão-Silva

O estudo do Planejamento familiar, no contexto da bioética, abre-se para diversas perspectivas, entre elas a valorização dos seus diferentes atores. Situado neste contexto o artigo tem como objetivo identificar o perfil de gênero na produção científica sobre Planejamento Familiar no Brasil, entre 2000 e 2014, assim como a área de formação e especialização dos autores. Foram utilizadas metodologias que permitiram mapear o estado da arte do tema estudado, a partir de uma revisão da literatura. O resultado da pesquisa identifica que a produção científica sobre Planejamento Familiar no Brasil se compõe de perfil destacadamente feminino (71,76%). Dos 73 artigos analisados, 42 (57,53%) o foco do tema está direcionado à mulher assim como evidencia-se a área de ciências da saúde com maior concentração das publicações do tema.  Este aspecto da pesquisa abre para uma realidade complexa onde se buscam criticamente as razões para a pesquisa em Planejamento Familiar ter ênfase na mulher e ser um tema de relevância nas ciências da saúde.Palavras-chave: Produção científica, Planejamento Familiar, Gênero.  ABSTRACT: The study of Family Planning, in the context of bioethics, opens to diverse perspectives, among them the appreciation of their different agents. Situated in this context the article aims to identify the profile of gender in scientific literature on Family Planning in Brazil, between 2000 and 2014, as well as the area of training and specialization of the authors. Methodologies were used which allowed to map the State of the art of the subject studied, from a review of the literature. The results found identify that the scientific production on Family Planning in Brazil is formed with a outstandingly female profile (71,76%). Of the 73 articles examined, 42 (57.53%) the focus of the topic is directed to women as well as showing the health sciences area with highest concentration of publications. This aspect of the research opens to a complex reality where we seek critically the reasons for Research in Family Planning have emphasis on woman and be a topic of relevance in health sciences.Keywords: Scientific Production, Family Planning, Gender.


Author(s):  
Muhammad Yousaf ◽  
Petr Bris

A systematic literature review (SLR) from 1991 to 2019 is carried out about EFQM (European Foundation for Quality Management) excellence model in this paper. The aim of the paper is to present state of the art in quantitative research on the EFQM excellence model that will guide future research lines in this field. The articles were searched with the help of six strings and these six strings were executed in three popular databases i.e. Scopus, Web of Science, and Science Direct. Around 584 peer-reviewed articles examined, which are directly linked with the subject of quantitative research on the EFQM excellence model. About 108 papers were chosen finally, then the purpose, data collection, conclusion, contributions, and type of quantitative of the selected papers are discussed and analyzed briefly in this study. Thus, this study identifies the focus areas of the researchers and knowledge gaps in empirical quantitative literature on the EFQM excellence model. This article also presents the lines of future research.


Author(s):  
Admink Admink

Аналізується тематичний ряд наукових статей, надісланих до фахового, науко-метричного збірника «Українська культура: минуле, сучасне, шляхи розвитку», Вип. 30 («мистецтвознавство»), виявляється проблематика, що є предметом наукового зацікавлення дослідників.Ключові слова: науковий пошук, культурно-мистецьке життя, сучасність, історична ретроспектива, міжкультурний вимір. The thematic number of scientific articles is sent to the professional, scientific and metric digest «Ukrainian Culture: Past, Present, Ways of Development» (vol.30, "Art Studies") and analyzed. The issues, which are the subject of scientific interest of researchers, are revealed. Key words: scientific search, cultural and artistic life, modernity, historical retrospective, intercultural dimension. Key words: scientific search, cultural and artistic life, modernity, historical retrospective, intercultural dimension.  


Polymers ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 1977
Author(s):  
Lorenzo Vallan ◽  
Emin Istif ◽  
I. Jénnifer Gómez ◽  
Nuria Alegret ◽  
Daniele Mantione

Certainly, the success of polythiophenes is due in the first place to their outstanding electronic properties and superior processability. Nevertheless, there are additional reasons that contribute to arouse the scientific interest around these materials. Among these, the large variety of chemical modifications that is possible to perform on the thiophene ring is a precious aspect. In particular, a turning point was marked by the diffusion of synthetic strategies for the preparation of terthiophenes: the vast richness of approaches today available for the easy customization of these structures allows the finetuning of their chemical, physical, and optical properties. Therefore, terthiophene derivatives have become an extremely versatile class of compounds both for direct application or for the preparation of electronic functional polymers. Moreover, their biocompatibility and ease of functionalization make them appealing for biology and medical research, as it testifies to the blossoming of studies in these fields in which they are involved. It is thus with the willingness to guide the reader through all the possibilities offered by these structures that this review elucidates the synthetic methods and describes the full chemical variety of terthiophenes and their derivatives. In the final part, an in-depth presentation of their numerous bioapplications intends to provide a complete picture of the state of the art.


Nutrients ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2653
Author(s):  
Matilde Roda ◽  
Natalie di Geronimo ◽  
Marco Pellegrini ◽  
Costantino Schiavi

Nutritional optic neuropathy is a cause of bilateral, symmetrical, and progressive visual impairment with loss of central visual acuity and contrast sensitivity, dyschromatopsia, and a central or centrocecal scotoma. The clinical features are not pathognomonic, since hereditary and toxic forms share similar signs and symptoms. It is becoming increasingly common due to the widespread of bariatric surgery and strict vegetarian or vegan diets, so even the scientific interest has recently increased. In particular, recent studies have focused on possible pathogenetic mechanisms, and on novel diagnostic and therapeutic strategies in order to prevent the onset, make a prompt diagnosis and an accurate nutritional supplementation, and to avoid irreversible optic nerve atrophy. Nowadays, there is clear evidence of the role of cobalamin, folic acid, thiamine, and copper, whereas further studies are needed to define the role of niacin, riboflavin, and pyridoxine. This review aims to summarize the etiology, diagnosis, and treatment of nutritional optic neuropathy, and it is addressed not only to ophthalmologists, but to all physicians who could come in contact with a patient with a possible nutritional optic neuropathy, being a fundamental multidisciplinary approach.


1985 ◽  
Vol 19 (1) ◽  
pp. 9-33 ◽  
Author(s):  
J. L. Berggren

In Recent Years, many discoveries in the history of Islamic mathematics have not been reported outside the specialist literature, even though they raise issues of interest to a larger audience. Thus, our aim in writing this survey is to provide to scholars of Islamic culture an account of the major themes and discoveries of the last decade of research on the history of mathematics in the Islamic world. However, the subject of mathematics comprised much more than what a modern mathematician might think of as belonging to mathematics, so our survey is an overview of what may best be called the “mathematical sciences” in Islam; that is, in addition to such topics as arithmetic, algebra, and geometry we will also be interested in mechanics, optics, and mathematical instruments.


Author(s):  
Tatiana V. Chernigovskaya ◽  

The paper discusses semiotic aspects of higher human functions and a possibility and relevance of traditional search for their neurophysiological basis. The state of the art on the subject is reviewed and the lack of data on anthropological specificity for reasoning, thinking, language and its AI modeling is highlighted. Experimental neuroscience presumes that if we know the characteristics of neu­rons and their connections, we automatically understand what mind and con­sciousness are. However, it is evident that such a paradigm does not allow us to get relevant answers to the main questions. I argue that the problem should be dealt with not only within the field of neurophysiology proper. Rather, such re­search should involve exploring the 'archeology' of mental processes as they are revealed in arts as well as in other symbolic spaces. The paper discusses the ade­quacy of physiological methodology when it is employed to demonstrate brain mechanisms of higher functions. Besides, I explore the relevance of juxta­posing similar data from other biological and artificial intelligent systems. I view language processing, mind and reasoning and 1st person experience (qualia) as human specific features, and questions the possibility of direct testing these phenomena. The paper links genetic, anthropological and neurophysio­logical data to semiotic activity and semiosphere formation as the basis for com­munication. The paper discusses the place of humans in the changing world in the context of new cognitive dimensions.


2015 ◽  
Vol 58 (1) ◽  
pp. 191-209 ◽  
Author(s):  
Joana Castro Pereira

Is it possible to talk about the rise of a new global (dis)order founded on the challenges posed by environmental issues? Through the review of the state of the art on the subject, this article analyzes the growing importance of the environment, and natural resources in particular, in international relations; and aims to raise awareness among International Relations scholars to the potential positive impact of the development of the discipline in integration with global environmental change studies.


1967 ◽  
Vol 71 (677) ◽  
pp. 344-348
Author(s):  
J. V. Connolly

During the past two years, there has been a sharp acceleration to the interest which industry has displayed in the subject of management education. This can be attributed to these factors: —(a) A more widespread realisation of the gap developing between the UK and a number of foreign economies, as manifested by diverging rates of the major economic indicators.(b) The attainment of top-management responsibilities by a younger generation of managers, many of whom had been given some earlier training and who were more conscious of its value than the incumbents of the job from earlier generations.(c) The publication of the Franks, Robbins and (in the aerospace industry) the Plowden reports.(d) The impact of the Industrial Training Boards making it manifest, in terms of serious levies, that training was an economic necessity and therefore must be investigated thoroughly.Notwithstanding the widespread awakening of interest, it is very belated and sets numerous problems. The problems are in two areas—scale and quality.


1979 ◽  
Vol 17 (1) ◽  
pp. 171-184
Author(s):  
A Orte

The scientific interest in Commission 31 topics and their applicability to new and practical fields is exponentially growing, pushing towards the recognition of new problems and subsequent research. In some cases as in Primary Standards the state of the art seems to be rather close to the actual and imagined needs. In other cases as in worldwide precise and accurate synchronization, we have to recognize that we still are far from the goals.


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