scholarly journals Risk Communication in Earthquake Vulnerability in District Bagh, Azad Jammu And Kashmir: Review of Literature and Pilot Study

2018 ◽  
Vol 2 (2) ◽  
pp. 58-101
Author(s):  
Kamran Azam ◽  
Keyword(s):  
Pilot Study ◽  
Risk Communication ◽  
Residential Buildings ◽  
Global Scale ◽  
The Body ◽  
Jammu And Kashmir ◽  
Prime Concern ◽  
Earthquake Vulnerability ◽  
The Impact

This study is mainly concerned to assess the role of Risk Communication in Earthquake Vulnerability and its impacts on Building Resilience in District Bagh Azad Jammu and Kashmir. Disaster resilience is gaining attention from all over the world. More specifically, seismic resilience in buildings is of prime concern among governmental bodies of developed as well as developing countries. This is partially due to the fact that the collapsing of vulnerable structures contribute to a great proportion of the number of fatalities in the wake of increasing Seismicity. Secondly, the recurrence of earthquakes on a global scale is increasing with increase in its magnitude. This study was focused to assess the impact and role of risk communication in earthquake vulnerability in district Bagh, Azad Jammu and Kashmir in enhancing resilience of residential buildings and also its moderating role between Earthquake Vulnerability and resilience of residential buildings in study area. In fact there is great gape; people in the vulnerable areas do not get required information about various hazards. For this study District Bagh of Azad Jammu and Kashmir was selected due to the facts, it suffered a lot during 2005 Earthquake and still it is prone to more damages due to lack of implementation of building codes and requisite information on the vulnerability. An exploratory type of study has been conducted. For pilot study 50 respondents were approached for collection of data with the help of questionnaires in different areas of District Bagh. Findings of the pilot study along with recommendations for policy makers, managers and target readers have been given in detail. Contribution to the body of knowledge and future call is also jotted down. If people are educated well about various hazards they can reduce the vulnerability to a great extent. Nevertheless, through better integration of risk communication means and enhancing level of awareness would prove instrumental in overcoming the lapses Keywords: Risk communication, Earthquake vulnerability and Resilience.

scholarly journals Erythrocytes: Central Actors in Multiple Scenes of Atherosclerosis

2021 ◽  
Vol 22 (11) ◽  
pp. 5843
Author(s):  
Chloé Turpin ◽  
Aurélie Catan ◽  
Olivier Meilhac ◽  
Emmanuel Bourdon ◽  
François Canonne-Hergaux ◽  
...  
Keyword(s):  
Iron Homeostasis ◽  
The Body ◽  
Diabetic Patients ◽  
Special Focus ◽  
Plaque Progression ◽  
Cell Dysfunction ◽  
Circulating Cells ◽  
The Impact ◽  
Progression Of Atherosclerosis

The development and progression of atherosclerosis (ATH) involves lipid accumulation, oxidative stress and both vascular and blood cell dysfunction. Erythrocytes, the main circulating cells in the body, exert determinant roles in the gas transport between tissues. Erythrocytes have long been considered as simple bystanders in cardiovascular diseases, including ATH. This review highlights recent knowledge concerning the role of erythrocytes being more than just passive gas carriers, as potent contributors to atherosclerotic plaque progression. Erythrocyte physiology and ATH pathology is first described. Then, a specific chapter delineates the numerous links between erythrocytes and atherogenesis. In particular, we discuss the impact of extravasated erythrocytes in plaque iron homeostasis with potential pathological consequences. Hyperglycaemia is recognised as a significant aggravating contributor to the development of ATH. Then, a special focus is made on glycoxidative modifications of erythrocytes and their role in ATH. This chapter includes recent data proposing glycoxidised erythrocytes as putative contributors to enhanced atherothrombosis in diabetic patients.

scholarly journals The confidence delusion: A sociological exploration of participants’ confidence in sport-for-development

2018 ◽  
Vol 55 (4) ◽  
pp. 383-398
Author(s):  
David S Scott
Keyword(s):  
Personal Development ◽  
The Body ◽  
Individual Interviews ◽  
Everyday Lives ◽  
Sport For Development ◽  
Development Capacity ◽  
The Social ◽  
Ethnographic Methodology ◽  
The Impact

Although sport is widely utilised as a tool for personal development, capacity building, and fostering peace, there are still numerous theoretical gaps in our knowledge about how sport influences individuals’ identities, and how this translates into their everyday lives. Within the academic literature there has been seemingly little focus placed upon participants’ emotional and embodied accounts of their sport-for-development (SfD) experiences. This paper uses phenomenologically-inspired theory to explore individuals’ lived experiences of a SfD course, and their descriptions of the social interactions and feelings of confidence they encountered, in order to address this lack of experiential data. An ethnographic methodology was used to collect data through four sports leadership course observations, and cyclical interviews over 4–10 months with eleven course attendees, plus individual interviews with five tutors. Participants’ understandings of their course experiences and the subsequent influence these understandings had on their lives were described through their use of the term confidence. A further phenomenological and sociological interrogation of this term enabled confidence to be seen as being experienced as a ‘frame’ and ‘through the body’ by participants. This study provides original conceptualisations of confidence in relation to participants’ SfD experiences, as well as important discussions regarding the role of emotions and embodiment in understanding the impact of SfD on participants’ everyday lives.

The Impact of the Global, Extensible Electronic Health Record

2011 ◽  
pp. 3-13 ◽  
Author(s):  
David W. Forslund ◽  
David G. Kilman
Keyword(s):  
Electronic Health Records ◽  
Negative Impact ◽  
Global Scale ◽  
Global Perspective ◽  
Health Records ◽  
Technological Advances ◽  
The World ◽  
Electronic Health ◽  
The Impact

With the arrival of the “World Wide Web,” we have witnessed a transition toward a truly global perspective with respect to electronic health records. In recent years, much more discussion has focused on the potential for international virtual electronic health records and what is required for them to become a reality in the world today (Kilman & Forslund, 1997). As the Internet becomes more ubiquitous and Web-enabled, we see access to electronic health records using these technologies becoming more commonplace. Even so, these Web-enabled health records still remain technologically isolated from other medical records in the distributed continuum of care; much of the standardization challenge still stands before us. We have witnessed startling technological advances, but we still face considerable obstacles to the goal of having globally standardized electronic health records. In this chapter we describe some of the issues associated with Web-enabled health records, the role of standards in the evolution of Web-enabled health records, and some of the barriers to the development of globally accessible electronic health records. We discuss possible ways to overcome these barriers and the kinds of benefits and opportunities that global health records will help provide. The global scale perspective makes more evident the very real and potentially tragic consequences of prolonged and unnecessary delays in deploying these technologies. Therefore, in an effort to promote a fuller consciousness of health safety, the chapter concludes with a comparative look at the negative impact of impediments in the movement toward global extensible electronic health records.

scholarly journals Racism, racial life events and mental ill health

2001 ◽  
Vol 7 (5) ◽  
pp. 343-349 ◽  
Author(s):  
Dinesh Bhugra ◽  
Oyedeji Ayonrinde
Keyword(s):  
Psychiatric Disorders ◽  
Life Events ◽  
Common Mental Disorders ◽  
The Body ◽  
Mental Illnesses ◽  
Positive Life Events ◽  
Minority Ethnic Groups ◽  
Different Cultures ◽  
The Impact

The association of life events with the onset of various psychiatric disorders is well-known. The body of evidence has highlighted the impact of negative or positive life events on the genesis of common mental disorders, especially depression. These findings have been replicated across different cultures, although the impact of different life events varies between cultures. In addition, the roles of chronic difficulties (defined in Life events and psychiatric disorders, below) and resulting ongoing chronic stress have been shown to contribute to vulnerability to certain mental illnesses. However, data on the impact of life events, especially those perceived as racial, on members of minority ethnic groups are rather sparse. The questions that need to be addressed concern the perception of life events as racial, the role of pervasive and perceived institutional and individual racism, and chronic difficulties.

scholarly journals A Conceptual Model Proposal: Universities as Culture Change Agents for Sustainable Development

2020 ◽  
Vol 12 (11) ◽  
pp. 4635 ◽  
Author(s):  
Małgorzata Dzimińska ◽  
Justyna Fijałkowska ◽  
Łukasz Sułkowski
Keyword(s):  
Sustainable Development ◽  
Literature Review ◽  
Conceptual Model ◽  
Culture Change ◽  
Change Agents ◽  
The Body ◽  
Quality Culture ◽  
The University ◽  
The Impact

This paper aims to propose a conceptual model that synthesizes the existing findings concerning universities as culture change agents for sustainable development. The model could serve as a guidance on how universities might get involved in the pro-SD activities. It also underlines the prerequisite of the quality culture that should be introduced within all the activities of universities to successfully act as culture change agents for SD. This paper builds upon the holistic and inter-disciplinary approach to demonstrate that SD does not happen in isolation and that the role of universities in its creation is significant. This study includes a literature review to contextualize the impact of universities on culture and their potential role in SD. The conclusions stemming from the literature review materialize in the proposal of the conceptual model of the university as the culture change agent for SD. The elaborated framework responds to the need for greater clarity, ordering and systematization of the role of universities in the processes of initiating, promoting and modelling the SD-oriented changes while appreciating the role of culture as an enabler, means of social change and a result of SD-focused interventions. The paper contributes to the body of knowledge by offering a novel perspective on the assumed interrelations between university, its quality culture, university main operations such as education, research and engagement with the society as well as the culture and the agency of stakeholders in the context of meeting the world’s current demands without compromising the needs of future generations.

scholarly journals How Pro-Environmental Legal Regulations Affect the Design Process and Management of Multi-Family Residential Buildings in Poland

Energies ◽  
2020 ◽  
Vol 13 (20) ◽  
pp. 5449
Author(s):  
Miłosz Raczyński ◽  
Radosław Rutkowski
Keyword(s):  
Design Process ◽  
Energy Supply ◽  
Residential Buildings ◽  
Design Phase ◽  
Legal Regulations ◽  
Extensive Experience ◽  
Number Of Factors ◽  
The Impact

This article addresses issues related to the quality of design and subsequent management of multi-family residential buildings in the context of their energy supply. The framework of the analysis carried out here are pro-environmental legal regulations currently in force in Poland. This article describes the impact of these regulations on the design process and the role of the designer. The requirements have been defined and the constraints have been identified. A number of factors directly related to the nature and parameters of the designed buildings and their location have been taken into consideration. On the basis of this study, the impact of legal regulations both on the method of energy supply in the buildings and on their later use and management have been presented. Positive and negative aspects of the analyzed regulations have been indicated and directions for their evaluation and optimization have been proposed. The research was carried out using real buildings, both completed and in the design phase. This article is based on the authors’ extensive experience in designing multi-family residential buildings in Poland.

Recent advances in the analysis of nanoparticle-protein coronas

Nanomedicine ◽  
2020 ◽  
Vol 15 (10) ◽  
pp. 1037-1061
Author(s):  
Muhammad Ovais ◽  
Susheel Kumar Nethi ◽  
Saleem Ullah ◽  
Irshad Ahmad ◽  
Sudip Mukherjee ◽  
...  
Keyword(s):  
Protein Corona ◽  
Recent Decade ◽  
The Body ◽  
Pharmacokinetics And Pharmacodynamics ◽  
Physiological Factors ◽  
Characterization Methods ◽  
Biological Fate ◽  
Circulation Distribution ◽  
The Impact

In spite of radical advances in nanobiotechnology, the clinical translation of nanoparticle (NP)-based agents is still a major challenge due to various physiological factors that influence their interactions with biological systems. Recent decade witnessed meticulous investigation on protein corona (PC) that is the first surrounds NPs once administered into the body. Formation of PC around NP surface exhibits resilient effects on their circulation, distribution, therapeutic activity, toxicity and other factors. Although enormous literature is available on the role of PC in altering pharmacokinetics and pharmacodynamics of NPs, understanding on its analytical characterization methods still remains shallow. Therefore, the current review summarizes the impact of PC on biological fate of NPs and stressing on analytical methods employed for studying the NP-PC.

scholarly journals What goes up must come down Biomechanical impact analysis of jumping locusts

2017 ◽  
Author(s):  
Simon V. Reichel ◽  
Susanna Labisch ◽  
Jan-Henning Dirks
Keyword(s):  
Impact Analysis ◽  
Schistocerca Gregaria ◽  
Impact Damage ◽  
Landing Site ◽  
The Body ◽  
Adhesive Pads ◽  
Degree Of Control ◽  
Free Falling ◽  
The Impact

AbstractMany insects are able to precisely control their jumping movements. Previous studies have shown that many falling insects have some degree of control of their landing-orientation, indicating a possible significant biomechanical role of the exoskeleton in air righting mechanisms. Once in the air, the properties of the actual landing site are almost impossible to predict. Falling insects thus have to cope mostly with the situation at impact. What exactly happens at the impact? Do locusts actively ‘prepare for landing’ while falling, or do they just ‘crash’ into the substrate?Detailed impact analyses of free falling Schistocerca gregaria locusts show that most insects typically crashed onto the substrate. There was no notable impact-reducing behaviour (protrusion of legs, etc.). Independent of dropping angle, both warm and cooled locusts mostly fell onto head and thorax first. Our results also show that alive warm locusts fell significantly faster than inactive or dead locusts. This indicates a possible tradeoff between active control vs. reduced speed. Looking at the morphology of the head-thorax connection in locusts, we propose that the anterior margin of the pronotum might function as a ‘toby collar’ structure, reducing the risk of impact damage to the neck joint. Interestingly, at impact alive insects also tended to perform a bending movement of the body.This biomechanical adaptation might reduce the rebound and shorten the time to recover. The adhesive pads also play an important role to reduce the time to recover by anchoring the insect to the substrate.

scholarly journals Consequences of accelerated Global Warming on nature and economy and the remedies for Global Green Economy

2013 ◽  
Vol 3 (1) ◽  
Author(s):  
Navneet Gera
Keyword(s):  
Global Warming ◽  
Human Resource ◽  
Co2 Emission ◽  
Global Scale ◽  
Green Economy ◽  
Oil Consumption ◽  
Root Cause ◽  
Global Issue ◽  
The Impact

Abstract: Global warming is the problem of 21st century for the globe. The root cause of problem is heavy oil consumption, deforestation, CO2 emission due to human and industrial activities and the rising threats of globalization like terrorism etc. This paper will address the impact of global warming on the Industries, human resource and the flora and fauna. The human resource has made a significant change in the current environment with the collective use of industries and the other GHG (Green House Gases) causing disturbance in the environment. In addition, the human resource is thinking on this issue, as it has become a global issue. There have been initiatives taken on Global Scale when Kyoto protocol agreement was signed which is in continuation till 2012. There have been further initiatives when the Ministers from across the global met at Copenhagen but at the end of the end there have been no discrete plans for Global Warming. Though it is a problem but how certainly can we manage this is more important. Global warming solutions can reduce the amount of heat-trapping gases that we emit into the atmosphere. Among the solutions, is a model G2I3 addressed in this paper and the role of every Individual which can make a great impact on the environmental problems.

scholarly journals Integrated Bioinformatics Data Analysis and Experimental Studies Reveals Prognostic Significance of ALDH Family in Endometria Cancer

2021 ◽  
Author(s):  
Zhou-Tong Dai ◽  
Yuan Xiang ◽  
Xing-Hua Liao
Keyword(s):  
Cell Lines ◽  
Cox Regression ◽  
Prognostic Significance ◽  
Experimental Studies ◽  
Female Reproductive Tract ◽  
The Body ◽  
Mouse Tumor ◽  
The Impact

Abstract Background Uterine Corpus Endometrial Cancer (UCEC) is one of the three common malignant tumors of the female reproductive tract. According to reports, the cure rate of early UCEC can reach 95%. Therefore, the development of prognostic markers will help UCEC patients to find the disease earlier and develop treatment earlier. The ALDH family was first discovered to be the essential gene of the ethanol metabolism pathway in the body. Recent studies have shown that ALDH can participate in the regulation of cancer. Methods We used the gene profile data of 33 cancers in the TCGA database to analyze the expression and survival of the ALDH family. GO, KEGG, PPI multiple functional analysis was used to predict the regulatory role of ALDH family in cancer. In addition, using CCK-8, colony formation, nude mouse tumor formation and other methods, the in vitro function of UCEC cancer cell lines was tested to further confirm the key role of ALDH2 expression in the proliferation of UCEC cell lines. Finally, Lasso and Cox regression methods were used to establish an overall survival prognosis model based on ALDH2 expression. Result In our research, we explored the expression of ALDH family in 33 cancers. It was found that ALDH2 was abnormally expressed in UCEC. Besides, in vivo and in vitro experiments were conducted to explore the effect of ALDH2 expression on the proliferation of UCEC cell lines. Meanwhile, the change of its expression is not due to gene mutations, but is regulated by miR-135-3p. At the same time, the impact of ALDH2 changes on the survival of UCEC patients is deeply discussed. Finally, a nomogram for predicting survival was constructed, with a C-index of 0.798 and AUC of 0.764. Conclusion This study suggests that ALDH2 may play a crucial role in UCEC progression and has the potential as a prognostic biomarker of UCEC.

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